Monkeypox:A comprehensive review of a multifaceted virus
作者机构:Deanery of Biomedical Sciences at Edinburgh Medical SchoolUniversity of EdinburghEdinburgh EH105HFUnited Kingdom Online Research Club(http://***)Nagasaki 852-8523Japan School of Public HealthImperial College LondonLondon SW72BXUnited Kingdom Global Clinical Scholars Research TrainingHarvard Medical SchoolBostonMA 02115USA Tata Memorial HospitalVaranasi 400012India DataQ HealthKarachi 75100Pakistan Department of Infection ControlBinh Dinh Provincial General HospitalBinh Dinh 55000Vietnam Faculty of MedicineZagazig UniversityZagazig 44519Egypt School of Tropical Medicine and Global HealthNagasaki UniversityNagasaki 852-8523Japan
出 版 物:《Infectious Medicine》 (感染医学(英文))
年 卷 期:2023年第2卷第2期
页 面:74-88页
学科分类:1001[医学-基础医学(可授医学、理学学位)] 100104[医学-病理学与病理生理学] 10[医学]
基 金:Abrar Fahad Mahbub Bangladesh Shishu Hospital & Institute Department of Paediatric Surgery
主 题:Monkeypox Orthopoxvirus Outbreak Smallpox
摘 要:In May 2022,the world witnessed the re-emergence of the zoonotic disease monkeypox.While this was not the first epidemic of this disease,what differentiated the outbreak was the rapid global spread and increase of cases,which led the WHO to declare monkeypox a global health emergency.Although the disease spreads mainly through inadequately cooked meat of various rodent species,this virus also shows droplet,respiratory,sexual,and even vertical transmission.Monkeypox further multiplies in lymphoproliferative organs and presents with a classical smallpox-like rash,fever,headache,and muscle aches.Diagnosis is confirmed with a polymerase-chain-reaction test and is managed largely supportively with possible usage of some antivirals and immunoglobulins.Moreover,some pre-exposure and postexposure prophylactic vaccines have been developed.This paper aims to conduct an in-depth review of the historical epidemics,transmission,pathophysiology,clinical presentation,and management of the monkeypox disease.