Chicken egg yolk antibodies (IgY) as non-antibiotic production enhancers for use in swine production： a review

作     者：Xiaoyu Li Lili Wang Yuhong Zhent Shuying Li Yongping Xu 

作者机构：School of Life Science and TechnologyDalian University of TechnologyDalian 116024China Ministry of Education Center for Food Safety of Animal OriginDalian 116620China Department of PharmacyDalian Medical UniversityDalian 116044China Dalian SEM Bio-Engineering Technology Co.LtdDalian 116620China 

出 版 物：《Journal of Animal Science and Biotechnology》 (畜牧与生物技术杂志（英文版）)

年 卷 期：2016年第7卷第1期

页      面：57-66页

核心收录：

学科分类：0905[农学-畜牧学] 09[农学] 

基　　金：supported by funds from the National Natural Science Foundation of China(31001053 30371053 30871806) 

主　　题：Diarrhea Disease control Egg yolk antibodies IgY Swine 

摘      要：In recent years, the use of in-feed antibiotics for growth and disease prevention in livestock production has been under severe scrutiny. The use and misuse of in-feed antibiotics has led to problems with drug residues in animal products and increased bacterial resistance. Chicken egg yolk antibodies （IgY） have attracted considerable attention as an alternative to antibiotics to maintain swine health and performance. Oral administration of IgY possesses many advantages over mammalian IgG such as cost-effectiveness, convenience and high yield. This review presents an overview of the potential to use IgY immunotherapy for the prevention and treatment of swine diarrhea diseases and speculates on the future of IgY technology. Included are a review of the potential applications of IgY in the control of enteric infections of either bacterial or viral origin such as enterotoxigenic Escherichia coil, Salmonella spp., rotavirus, porcine transmissible gastroenteritis virus, and porcine epidemic diarrhea virus. Some potential obstacles to the adoption of IgY technology are also discussed.