HPTLC-MS: an advance approach in herbal drugs using fingerprint spectra and mass spectroscopy
作者机构：Department of Pharmaceutical AnalysisISF College of PharmacyMoga 142001India Department of PharmacognosyISF College of PharmacyMoga 142001India
出 版 物：《Traditional Medicine Research》 (TMR传统医学研究)
年 卷 期：2023年第8卷第2期
页 面：21-35页
学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学]
主 题：chromatography herbal drug HPTLC-MS mass spectrometry quality control
摘 要：High-performance thin-layer chromatography-mass spectrometry(HPTLC-MS)is one of the most modern hyphenated analytical methods available ***-MS has recently been used to perform extensive analytical work using advanced features and still more analyses are in progress using these advanced *** medicines contain a wide range of bioactives that require proper identification for the activity and quality ***,herbal medicine identification and quality control have become increasingly popular using high-performance liquid chromatography mass *** aim of this paper is to provide a brief overview of recent method developments in analysis,15 most significant herbal drug applications with their chromatographic conditions,pharmacological actions,and solvents used in the present *** extensive literature search was performed incorporating several databases,notably,Web of Knowledge,PubMed and Google Scholar,and other relevant published *** previous research,HPTLC and its hyphenation with MS allowed for quantification of analytes in complex matrixes at nanogram and picogram *** a wide variety of analytes using these techniques has been extremely accurate,selective,and *** this review,the HPTLC-MS technique is discussed in relation to the quality control of herbal ***,15 herbal drugs were identified based on their RF values and m/z ratio by mass spectrometry by HPTLC-MS for the first *** this compilation,researchers can gain insights into HPTLC-MS techniques for resolving quality control issues with herbal drugs using their fingerprint ***,the application of HPTLC-MS methods could to be sufficiently precise and reproducible for established conditions and after validation may be used for routine quality control of herbal drugs/formulations in herbal industries.
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