Detection,isolation,and characterization of a novel impurity from several folic acid products

作     者：Qirong SHEN Quan HE Yuanjiang PAN Cuirong SUN Qirong SHEN;Quan HE;Yuanjiang PAN;Cuirong SUN

作者机构：College of Pharmaceutical SciencesZhejiang UniversityHangzhou310058China Department of ChemistryZhejiang UniversityHangzhou310027China Hangzhou Qianyuan Pollen Pharmaceutical Co.Ltd.Hangzhou310018China 

出 版 物：《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 (浙江大学学报（英文版）B辑（生物医学与生物技术）)

年 卷 期：2022年第23卷第7期

页      面：597-606页

核心收录：

学科分类：0710[理学-生物学] 1007[医学-药学(可授医学、理学学位)] 1001[医学-基础医学(可授医学、理学学位)] 0836[工学-生物工程] 10[医学] 

基　　金：This work was supported by the National Basic Research Program(973)of China(No.2016YFF0200503) the National Natural Science Foundation of China(No.21876146). 

主　　题：belongs characterization synthesize 

摘      要：Folic acid belongs to the group of water-soluble B vitamins and naturally exists in multiple forms in a wide variety of foods such as legumes,vegetables,liver,and milk(Iyer and Tomar,2009;Lyon et al.,2020).It is involved in many biochemical reactions critical for cell division,such as purine and pyrimidine biosynthesis,DNA/RNA biosynthesis,and amino acid metabolism(Iyer and Tomar,2009).Mammals cannot synthesize folic acid and thus they must acquire it from food.Although folic acid is ubiquitous in foods.