磷脂DHPC和短杆菌肽D相互作用的DSC研究

作     者：王邦宁 谈夫 

作者机构：中国科学院化学研究所北京100080 

出 版 物：《物理化学学报》 (Acta Physico-Chimica Sinica)

年 卷 期：1998年第14卷第6期

页      面：548-551页

核心收录：

学科分类：0710[理学-生物学] 071010[理学-生物化学与分子生物学] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 

基　　金：国家自然科学基金 

主　　题：生物膜 磷脂 GD DSC DHPC 相互作用 短杆菌肽 

摘      要：Changes of the behavior of the thermotropic phase transitions of the phospholipid DHPC by the action of miniprotein gramicidin D (G.D) have been studied by differential scanning calorimetry. The experimental results demonstrated that G.D could not remove the pretransition of DHPC, but the pretransition peak and the main transition peak of DHPC were incorporated into a broad peak. The pretransition temperature and the main transition temperature of DHPC decreased to different ex-tent. The sums of the pretransition and main transition enthalpies of DHPC showed a lineally decreasing relationship with increasing the mole fraction x_g of gramicidin D.