Dietary fatty acids in gut health: Absorption, metabolism and function

作     者：E.Xu Chao Chen Jie Fu Luoyi Zhu Junlan Shu Mingliang Jin Yizhen Wang Xin Zong E.Xu;Chao Chen;Jie Fu;Luoyi Zhu;Junlan Shu;Mingliang Jin;Yizhen Wang;Xin Zong

作者机构：Key laboratory of animal geneticsbreeding and reproduction in the plateau mountainous regionministry of educationcollege of aniaml scienceguizhou university550025 guiyangchina Key laboratory of molecular animal nutritionministry of educationcollege of animal scienceszhejiang university310058 hangzhouchina Key laboratory of animal nutrition and feed science in eastern chinaministry of agriculturecollege of animal scienceszhejiang university310058 hangzhouchina 

出 版 物：《Animal Nutrition》 (动物营养（英文版）)

年 卷 期：2021年第7卷第4期

页      面：1337-1344页

核心收录：

学科分类：090601[农学-基础兽医学] 09[农学] 0906[农学-兽医学] 

基　　金：funded by Zhejiang Provincial Key R&D Program of China(2021C02008) the National Natural Science Foundation of China(Grant Nos.31630075,32002185,and 31860648) Zhejiang Provincial Natural Science Foundation of China(Grant No.LQ21C170002) 

主　　题：Fatty acids Gut Absorption Metabolism G protein coupled receptor 

摘      要：In biological responses,fatty acids(FA)are absorbed and metabolized in the form of substrates for energy *** molecular structures(number of double bonds and chain length)and composition of dietary FA impact digestion,absorption and metabolism,and the biological roles of ***,increasing evidence indicates that FA are essentially utilized as an energy source and are signaling molecules that exert physiological activity of gut microbiota and immune *** addition,FA could serve as natural ligands for orphan G protein-coupled receptors(GPCR),also called free fatty acid receptors(FFAR),which intertwine metabolic and immune systems via multiple *** present review explores the recent findings on FA absorption and its impact on gut health,particularly addressing the mechanism by which dietary FA potentially influences intestinal microbiota and epithelial ***,this work attempts to uncover research ideas for devising future strategies for manipulating the composition of dietary FA to regulate gut health and support a normal immune system for metabolic and immune disorders.