多次经直肠电射精对精子参数及卵母细胞单精子显微注射结果的影响

作     者：Giulini S. Pesce F. Madgar I. 朱晓明 

作者机构：Department of Gynaecological Obstetric and Paediatric Scienc esUniv. of Modena and Reggio Emilia Modena Italy Dr. 

出 版 物：《世界核心医学期刊文摘（妇产科学分册）》 (Core Journal in Obstetrics/Gynecology)

年 卷 期：2005年第1卷第1期

页      面：35-35页

学科分类：1002[医学-临床医学] 100211[医学-妇产科学] 10[医学] 

主　　题：精子参数 显微注射 电射精 卵母细胞 经直肠 辅助生殖 脊髓损伤 临床妊娠 儿科学 精子活动力 

摘      要：Objective To compare semen parameters and intracytoplasmic sperm inje ction (IC SI) outcome in spinal cord-injured subjects who underwent single (group 1) or m ultiple (group 2) electroejaculations before ICSI. Design Prospective, randomize d, controlled study. Setting Department of gynecology, obstetrics, and pediatric science in a reproductive medicine unit at a major Italian university. Patient( s) Thirty-four healthy women with a male partner with SCI who were seeking assi sted reproduction services. Intervention(s) Transrectal electroejaculation, cont rolled ovarian hyperstimulation, and ICSI. Main outcome measure(s) Sperm concent ration, morphology, and motility and fertilization and pregnancy rates after ICS I. Result(s) Sperm was successfully retrieved in 94.1%of cases. In male subject s who underwent multiple electroejaculations, statistically significant improvem ents in sperm concentration and total sperm motility rate were observed. The ove rall fertilization rate was 63.6%. The number of oocytes retrieved and injected was comparable between the two groups. A total of nine clinical pregnancies wer e achieved. The pregnancy rate was statistically significantly higher in group 2 (n = 6/16; 37.5%) than in group 1 (n = 3/16; 18.75%). Conclusion(s) These dat a suggest that multiple electroejaculation has a positive effect on semen parame ters and ICSI outcome.