Neutralization of the SARS-CoV-2 Delta variant after heterologous and homologous BNT162b2 or ChAdOx1 nCoV-19 vaccination

作     者：Swantje I.Hammerschmidt Berislav Bosnjak Günter Bernhardt Michaela Friedrichsen Inga Ravens Alexandra Dopfer-Jablonka Markus Hoffmann Stefan Pöhlmann Georg M.N.Behrens Reinhold Förster 

作者机构：Institute of ImmunologyHannover Medical SchoolHannoverGermany Department for Rheumatology and ImmunologyHannover Medical SchoolHannoverGermany Infection Biology UnitGerman Primate Center-Leibniz Institute for Primate ResearchGöttingenGermany Faculty of Biology and PsychologyGeorg-August-University GöttingenGöttingenGermany German Center for Infection Research(DZIF)Partner Site Hannover-BraunschweigHannoverGermany German Center for Lung Research(DZL)HannoverGermany Cluster of Excellence RESIST(EXC 2155)Hannover Medical SchoolHannoverGermany 

出 版 物：《Cellular & Molecular Immunology》 (中国免疫学杂志（英文版）)

年 卷 期：2021年第18卷第10期

页      面：2455-2456页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 100705[医学-微生物与生化药学] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1001[医学-基础医学(可授医学、理学学位)] 100103[医学-病原生物学] 100401[医学-流行病与卫生统计学] 10[医学] 

基　　金：The study was approved by the Internal Review Board of Hannover Medical School(institutional review board no.8973_BO-K_2020,amendment Dec 2020) All participants gave written informed consent.Supported by the German Center for Infection Research TTU 01.938(Grant No.80018019238 to GMNB and RF) the German Center for Lung Research(Grant 82DZL002B1) Deutsche Forschungsgemeinschaft,(DFG,German Research Foundation)Excellence Strategy EXC 2155‘RESIST’(Project ID39087428 to RF) funds of the State of Lower Saxony(14-76103-184 CORONA-11/20 to RF,14-76103-184,MWK HZI COVID-19 to SP) funds of the BMBF(NaFoUniMedCovid19 FKZ:01KX2021,Projects B-FAST to RF,Projects 01KI2006D,01KI20328A,01KI20396,01KX2021 to SP) Deutsche Forschungsgemeinschaft,SFB 900/3(Projects B1,158989968 to RF,Projects PO 716/11-1,PO 716/14-1 to SP) 

主　　题：Delta homologous campaign 

摘      要：Since the beginning of the COVID-19 pandemic,divergent variants of concern(VoCs)of SARS-CoV-2 have evolved and become the most prevalent SARS-CoV-2 variants in distinct locations at different ***,the Delta variant(B.1.617.2)dominates infection events in large parts of the *** campaigns,however,still use SARS-CoV-2 vaccines based on the spike(S)protein of the original Wuhan virus.