Increasing prevalence of asthma and allergy in Beijing pre-school children: Is exclusive breastfeeding for more than 6 months protective?

作     者：QU Fang WESCHLER Louise B. SUNDELL Jan ZHANG YinPing 

作者机构：Department of Building Science Tsinghua University 

出 版 物：《Chinese Science Bulletin》 (Chinese Science Bulletin)

年 卷 期：2013年第58卷第25期

页      面：4190-4202页

核心收录：

学科分类：1002[医学-临床医学] 100202[医学-儿科学] 10[医学] 

基　　金：supported by the National Natural Science Foundation of China(51136002,51076079) the 12th Five-year National Key Technology R&D Program(2012BAJ02B03) the National High Technology Researchand Development Program of China(2010AA064903) Tsinghua University Initiative Scientific Research Program(20121088010) China Postdoctoral Science Foundation funded project(2012M510459) 

主　　题：母乳喂养 保护作用 学前儿童 患病率 哮喘 过敏 北京 风险因素 

摘      要：This study evaluated the prevalence and risk factors for asthma,allergy and related symptoms;and breastfeeding patterns and durations for 5479 Beijing children aged 3–*** of children in randomly selected kindergartens wrote responses to a questionnaire used *** study aimed to evaluate trends in the prevalence of asthma and related illnesses,and to determine whethermorebreastfeeding,defined as exclusive,6 months,was associated with reduced *** has increased in this age group between 1990 and 2011,with the steepest increase in the last 2–3 *** the total,14.2%(779)children were breastfed exclusively for6 *** efficacy ofmorebreastfeeding was tested in a subset with two strong risk factors,positive family history(for asthma and/or allergy)and male gender.Morebreastfeeding was found to be significantly protective(aOR 0.42,P0.05)for this subset against Doctor-diagnosed asthma(D-asthma).Protection that did not reach statistical significance was also found for this subset against Wheeze ever,Cough at night,Rhinitis ever,Doctor-diagnosed rhinitis(D-rhinitis)and *** greatest protective effects were found for girls with no family history of asthma or allergy,reaching statistical significance for Wheeze ever(aOR 0.48,P0.01),Cough at night(aOR 0.47,P0.01),D-asthma(aOR 0.14,P0.01)and Rhinitis ever(aOR 0.67,P0.05).Morebreastfeeding was not consistently associated with either a protective or risk effect for Eczema.