U-47700-Incidence of a Novel Psychoactive Substance in a Series of Medical Examiner Cases in Oakland County,MI

作     者：Lauren Aiello Emily Skwarek Daniel Isenschmidt Ljubisa J.Dragovic 

作者机构：Oakland County Medical Examiner's OfficePontiacMIUSA 

出 版 物：《Journal of Forensic Science and Medicine》 (法庭科学与法医学杂志（英文）)

年 卷 期：2020年第6卷第3期

页      面：105-109页

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

主　　题：Autopsy death investigation Michigan opioid overdose U-47700 

摘      要：U-47700 is one of many drugs that have been part of a group of compounds called novel psychoactive substances(NPS).U-47700 is a synthetic opioid agonist developed by Upjohn pharmaceuticals but never *** Oakland County Medical Examiner s Office in Pontiac,Michigan,began observing this compound in the fall of 2016,primarily in cases with other drugs of abuse and *** communication described 18 drug-related deaths in which U-47700 was *** U-47700 concentrations ranged from 0.37 to 370 ng/mL(mean 35 and median 4.9 ng/mL).Other opioids were detected in 83% of the *** drugs present in these cases are described as well as the scene *** only one death was likely due directly to U-47700,the cases described here demonstrate how NPS have become an important consideration in evaluating drug-related deaths today.