检索结果-南通市图书馆

Sorption of Perfluorooctane sulfonate(PFOS) including its isomers on hydrargillite as a function of pH,humic substances and Na2SO4

引用

Journal of Environmental Sciences 2022年第1期34卷 263-272页

作者： Jean-Noel Uwayezu Leo W.Y.Yeung Mattias Bäckström Man-Technology-Environment Research Centre(MTM) Örebro University70182ÖrebroSweden

Perfluorooctane sulfonate(PFOS)is a persistent organic pollutant(POP)and emergent contaminant that are widespread in the *** the mechanisms controlling the distribution of PFOS and its isomers between hydrargillite and the water phase is important in order to study their redistribution and mobility in the *** study investigated the effects of pH,humic acid,fulvic acid and Na_(2)SO_(4) on sorption of PFOS isomers to hydrargillite.A mixture of PFOS isomers was spiked into water and hydrargillite was added to the system and shaken for one day;the system was tested with different aqueous *** of PFOS isomers in the aqueous phase were quantified using an ultra-performance liquid chromatograph coupled to a triple quadrupole mass *** results showed that the distribution coefficients of PFOS isomers were found to be 0.76,0.71,0.93 and 0.90 at pH 6.5,for 3-/4-/5-PFOS,6-/2-PFOS,L-PFOS and total PFOS *** distribution coefficients increased at lower pH and decreased at alkaline *** presence of humic substances(HS)increased the sorption slightly at the environmental pH of 6.5,although a competition effect was observed during acidic conditions.A tendency of PFOS distribution to hydrargillite in the presence of Na_(2)SO_(4) was like its behavior in the presence of HS although the mechanisms behind the sorption were interpreted *** study revealed that L-PFOS was readily sorbed when no other chemicals were added or in 20 mg/L FA or 100 mg/L Na_(2)SO_(4).We suggest that an increase in PFOS sorption in the presence of HS may be due to hydrophobic mechanisms while Na_(2)SO_(4) contributed to increased sorption through ionic strength effects.

关键词： Hydrargillite Perfluorooctane sulfonate Sorption Humic substances Electrostatic,Ionic strength

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Diagnosis and management of microscopic colitis

引用

World Journal of Gastroenterology 2008年第48期14卷 7280-7288页

作者： Curt Tysk Johan Bohr Nils Nyhlin Anna Wickbom Sune Eriksson Department of Medicine Division of Gastroenterology rebro University Hospital and School of Health and Medical Sciences rebro University Department of Pathology rebro University Hospital

Microscopic colitis, comprising collagenous and lymphocytic colitis, is characterized clinically by chronic watery diarrhea, and a macroscopically normal colonic mucosa where diagnostic histopathological features are seen on microscoplc incidence of each disorder examination. The annual is 4-6/100000 inhabitants, with a peak incidence in 60-70-year-old individuals and a noticeable female predominance for collagenous colitis. The etiology is unknown. Chronic diarrhea, abdominal pain, weight loss, fatigue and fecal incontinence are common symptoms, which impair the health-related quality of life of the patient. There is an association with other autoimmune disorders such as celiac disease, diabetes mellitus, thyroid disorders and arthritis. Budesonide is the best-documented shortterm treatment, but the optimal long-term strategy needs further study. The long-term prognosis is good and the risk of complications including colonic cancer is low.

关键词： Microscopic colitis Collagenous colitis Lymphocytic colitis Chronic diarrhea Budesonide

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A short P-wave duration is associated with incident heart failure in the elderly: a 15 years follow-up cohort study

引用

Journal of Geriatric Cardiology 2022年第9期19卷 643-650页

作者： Bozena Ostrowska Lars Lind Elena Sciaraffia Carina Blomström-Lundqvist Department of Medical Sciences Uppsala UniversityUppsalaSweden School of Medical Science Faculty of Medi-cine and HealthÖrebro UniversityÖrebroSweden

BACKGROUND Early identification of patients at risk of congestive heart failure(HF)may alter their poor *** aim was therefore to test whether simple electrocardiographic variables,the P-wave and PR-interval,could predict incident *** The PIVUS(Prospective Investigation of the Vasculature in Uppsala Seniors)study(1016 individuals all aged 70 years,50%women)was used to identify predictors of *** with prevalent HF,QRS duration≥130 ms,atrial tachyar-rhythmias,implanted pacemaker/defibrillator,second-and third-degree atrioventricular block or delta waves at baseline were *** proportional hazard analysis was used to relate the PR interval,P-wave duration(Pdur)and amplitude(Pamp),measured in lead V1,to incident *** was performed for gender,RR-interval,beta-blocking agents,systolic blood pressure,body mass index and *** Out of 836 subjects at risk,107 subjects were diagnosed with HF during a follow-up of 15 *** the multivariate analysis,there was a strong U-shaped correlation between Pdur in lead V1 and incident HF(P=0.0001)which was significant for a Pdur<60 ms[HR=2.75;95%CI:1.87-4.06,at Pdur 40 ms]but not for prolonged *** was no significant relationship between incident HF and the PR-interval or the Pamp.A Pdur<60 ms improved discrimination by 3.7%when added to the tradi-tional risk factors including sex,RR-interval,beta-blocking agents,systolic blood pressure,BMI and smoking(P=0.048).CONCLUSIONS A short Pdur,an easily measured parameter on the ECG,may potentially be a useful marker of future HF,enabling its early detection and prevention,thus improving outcomes.

关键词： prevention incident wave

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Why do fish school？

引用

Current Zoology 2012年第1期58卷 116-128页

作者： Larsson, Matz The Cardiology Clinic Örebro University Hospital SE -701 85 Örebro Sweden The Institute of Environmental Medicine Karolinska Institute SE-171 77 Stockholm Sweden

Synchronized movements （schooling） emit complex and overlapping sound and pressure curves that might confuse the inner ear and lateral line organ （LLO） of a predator. Moreover, prey-fish moving close to each other may blur the elec- tro-sensory perception of predators. The aim of this review is to explore mechanisms associated with synchronous swimming that may have contributed to increased adaptation and as a consequence may have influenced the evolution of schooling. The evolu- tionary development of the inner ear and the LLO increased the capacity to detect potential prey, possibly leading to an increased potential for cannibalism in the shoal, but also helped small fish to avoid joining larger fish, resulting in size homogeneity and, accordingly, an increased capacity for moving in synchrony. Water-movements and incidental sound produced as by-product of locomotion （ISOL） may provide fish with potentially useful information during swimming, such as neighbour body-size, speed, and location. When many fish move close to one another ISOL will be energetic and complex. Quiet intervals will be few. Fish moving in synchrony will have the capacity to discontinue movements simultaneously, providing relatively quiet intervals to al- low the reception of potentially critical environmental signals. Besides, synchronized movements may facilitate auditory grouping of ISOL. Turning preference bias, well-functioning sense organs, good health, and skillful motor performance might be important to achieving an appropriate distance to school neighbors and aid the individual fish in reducing time spent in the comparatively less safe school periphery. Turning preferences in ancestral fish shoals might have helped fish to maintain groups and stay in for- mation, reinforcing aforementioned predator confusion mechanisms, which possibly played a role in the lateralization of the ver- tebrate brain [Current Zoology 58 （1）： 116-128, 2012].

关键词： Group synchrony Hearing in fish Lateral line Electro-sensory system Sensory reafference Lateralization

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Colorectal cancer in patients with inflammatory bowel disease:Can we predict risk?

引用

World Journal of Gastroenterology 2012年第31期18卷 4091-4094页

作者： Vibeke Andersen Jonas Halfvarson Ulla Vogel Medical Department Sygehus Sφnderjylland AabenraaDK-6200 AabenraaDenmark Institute of Regional Health Services Research University of Southern DenmarkDK-5000 OdenseDenmark Department of Internal Medicine rebro University Hospitalrebro Universityrebro 70185Sweden National Research Centre for the Working Environment DK-2100 CopenhagenDenmark

The inflammatory bowel diseases(IBD),Crohn's disease(CD) and ulcerative colitis(UC),may be complicated by colorectal cancer(CRC).In a recent populationbased cohort study of 47 347 Danish patients with IBD by Tine Jess and colleagues 268 patients with UC and 70 patients with CD developed CRC during 30 years of *** overall risk of CRC among patients with UC and CD was comparable with that of the general ***,patients diagnosed with UC during childhood or as adolescents,patients with long duration of disease and those with concomitant primary sclerosing cholangitis were at increased *** this commentary,we discuss the mechanisms underlying carcinogenesis in IBD and current investigations of genetic susceptibility in IBD *** advances will depend on the cooperative work by epidemiologist and molecular geneticists in order to identify genetic polymorphisms involved in IBD-associated *** ultimate goal is to incorporate genotypes and clinical parameters into a predictive model that will refine the prediction of risk for CRC in colonic *** challenge will be to translate these new findings into clinical practice and to determine appropriate preventive strategies in order to avoid CRC in IBD *** achieved knowledge may also be relevant for other inflammation-associated cancers.

关键词： Inflammatory bowel disease Crohn's dis-ease Ulcerative colitis Colorectal cancer Inflamma-tion-associated cancer Genetics Preventive strategies

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Contribution of precursor compounds to the release of per-and polyfluoroalkyl substances(PFASs) from waste water treatment plants(WWTPs)

引用

Journal of Environmental Sciences 2017年第11期29卷 80-90页

作者： Ulrika Eriksson Peter Haglund Anna K?rrman Man-Technology-Environment (MTM) Research Centre School of Science and Technology ?rebro University Department of Chemistry Umea University

Per-and polyfluoroalkyl substances（PFASs） are ubiquitous in sludge and water from waste water treatment plants, as a result of their incorporation in everyday products and industrial processes. In this study, we measured several classes of persistent PFASs,precursors, transformation intermediates, and newly identified PFASs in influent and effluent sewage water and sludge from three municipal waste water treatment plants in Sweden, sampled in 2015. For sludge, samples from 2012 and 2014 were analyzed as *** of precursors in sludge exceeded those of perfluoroalkyl acids and sulfonic acids（PFCAs and PFSAs）, in 2015 the sum of polyfluoroalkyl phosphoric acid esters（PAPs） were 15–20 ng/g dry weight, the sum of fluorotelomer sulfonic acids（FTSAs） was 0.8–1.3 ng/g,and the sum of perfluorooctane sulfonamides and ethanols ranged from non-detected to 3.2 ng/g. Persistent PFSAs and PFCAs were detected at 1.9–3.9 ng/g and 2.4–7.3 ng/g dry weight, respectively. The influence of precursor compounds was further demonstrated by an observed substantial increase for a majority of the persistent PFCAs and PFSAs in water after waste water treatment. Perfluorohexanoic acid（PFHxA）, perfluorooctanoic acid（PFOA）, perfluorohexane sulfonic acid（PFHxS）, and perfluorooctane sulfonic acid（PFOS）had a net mass increase in all WWTPs, with mean values of 83%, 28%, 37% and 58%,respectively. The load of precursors and intermediates in influent water and sludge combined with net mass increase support the hypothesis that degradation of precursor compounds is a significant contributor to PFAS contamination in the environment.

关键词： diPAPs FTSAs Waste water Daily discharge PFCA precursor

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Retinal pigment epithelium–Bruch’s membrane volume in grading of age-related macular degeneration

引用

International Journal of Ophthalmology(English edition) 2023年第11期16卷 1827-1831页

作者： Fabian Kananen Ilkka Immonen Department of Ophthalmology Örebro University HospitalÖrebro 70185Sweden Department of Ophthalmology and Otorhinolaryngology Helsinki UniversityHelsinki 00014Finland Department of Ophthalmology Helsinki University Central HospitalHelsinki 00014Finland

AIM:To assess the agreement of optical coherence tomography(OCT)algorithm-based retinal pigment epithelium–Bruch’s membrane complex volume(RBV)with fundus photograph-based age-related macular degeneration(AMD)***:Digital color fundus photographs(CFPs)and spectral domain OCT images were acquired from 96 elderly *** were graded according to Age-Related Eye Disease Study(AREDS)*** image segmentation and RBV data calculation were done with OrionTM *** and multivariate analyses were performed to find out whether AMD lesion features associated with higher ***:RBV correlated with AMD grading(rs=0.338,P=0.001),the correlation was slightly stronger in early AMD(n=52;rs=0.432,P=0.001).RBV was higher in subjects with early AMD compared with those with no AMD lesions evident in fundus photographs(1.05±0.20 vs 0.96±0.13 mm3,P=0.023).In multivariate analysis higher RBVs were associated significantly with higher total drusen(β=0.388,P=0.027)and pigmentation areas(β=0.319,P=0.020)in fundus photographs,whereas depigmentation area(β=-0.295,P=0.015)associated with lower ***:RBV correlate with AMD grading status,with a stronger association in patients with moderate,non-late AMD *** effect is driven mostly by lesions with drusen or *** with depigmentation tend to have lower *** is more comprehensive measurement of the key area of AMD pathogenesis,compared to sole drusen volume *** measurements are independent on grader variations and offer a possibility to quantify early and middle grade AMD lesions in a research setting,but may not substitute fundus photograph-based grading in the whole range of AMD spectrum.

关键词： age-related macular degeneration drusen optical coherence tomography Bruch’s membrane

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Perception of Student Life as Promoting Mental Health and Well-Being. A Study of First-Year Students in a Norwegian University

引用

International Journal of Mental Health Promotion 2021年第4期23卷 487-497页

作者： Anne Skoglund Kari Bjerke Batt-Rawden Agneta Schröder Oyfrid Larsen Moen Norwegian University of Science and Technology Gjøvik2802Norway University Health Care Research Center Faculty of Medicin and HealthÖrebro UniversityÖrebroSE-70185Sweden

In Norway,300,000 people attend higher *** in Europe,student numbers are also *** Great Britain,1.9 million people attended higher education in the academic year 2018–*** is a substantial part of the population,and the mental health and well-being of students are of prime *** year as a university student is a transitional period characterized by significant changes and constitutes an essential fundament for students in their student life and *** increasing number of students report having mental health problems to various *** the variety of perceptions of what may promote mental health and well-being is therefore of *** study aims to explore whetherfirst year students in higher education perceive student life as promoting their mental health and *** students were interviewed(n=20).Phenomenographic analysis was used to reveal variation in the students’*** descriptive categories were constructed,“The need to belong”and“The need for support,”withfive conceptions:the importance of the sponsorship week,small groups as a place to belong,being patient,a supportive environment and the university as a *** a sense of belonging and a sense of support was achieved varied among the participants,and the solution for how to achieve this lies in the students themselves,the way the university organizes the programmes and how the students are met by the administration,lecturers and fellow students.

关键词： Mental health students university well-being

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Perfluoroalkane acids in human milk under the global monitoring plan of the Stockholm Convention on Persistent Organic Pollutants(2008-2019)

引用

Frontiers of Environmental Science & Engineering 2022年第10期16卷 91-104页

作者： Heidelore Fiedler Mohammad Sadia Thomas Krauss Abeer Baabish Leo W.Y.Yeung School of Science and Technology MTM Research Centre(O)rebro UniversitySE-70182(O)rebroSweden Funda(c)ao Oswaldo Cruz(FIOCRUZ) Instituto Nacional de Controle de Qualidade em Saúde(INCQS)Avenida Brasil4365-Manguinhos EP 21.040-900Rio de Janeiro-RJBrazil

Within the global monitoring plan(GMP)established by article 16 of the Stockholm Convention on Persistent Organic Pollutants,perfluorooctane sulfonic acid(PFOS),perfluorooctanoic acid(PFOA),and perfluorohexane sulfonic acid(PFHxS)are recommended for analysis in core matrices to assess occurrence and changes geographically and with *** 101 samples consisting of 86 national pools and 15 pools from States in Brazil obtained between 2008 and 2019,PFHxS was detected in 17%of the national pools and none in *** and PFOS had a detection frequency of 100%and 92%,*** perfluoroalkane substances(PFAS)had either low detection frequencies and median values of zero(carboxylic acids C4-C11;except PFOA)or could not be quantified in any sample(sulfonic acids,C4-C10,and long-chain carboxylic acids,C_(12)-C_(14)).Correlation between PFOA and PFOS was moderately(r=0.58).Whereas median values were almost identical(18.9 pg/g *** PFOS;18.6 pg/g *** PFOA),PFOS showed larger ranges(<6.2 pg/g f.w.-212 pg/g f.w.)than PFOA(<6.2 pg/g f.w.-63.4 pg/g f.w.).It was shown that wealthier countries had higher PFOA concentrations than poorer *** difference in concentrations was found for samples collected in countries having or not having ratified the Stockholm Convention amendments to list PFOS or *** goal to achieve 50%decrease in concentrations within ten years was met by Antigua and Barbuda,Kenya,and Nigeria for PFOS and by Antigua and Barbuda for *** a few cases,increases were observed;one country for PFOS,four countries for PFOA.

关键词： Human biomonitoring Human breast milk LC-MS/MS analysis Lifestyle parameters

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Eosinophil associated genes in the inflammatory bowel disease 4 region:Correlation to inflammatory bowel disease revealed

引用

World Journal of Gastroenterology 2012年第44期18卷 6409-6419页

作者： Kristin Blom Jenny Rubin Jonas Halfvarson Leif Trkvist Anders Rnnblom Per Sangfelt Mikael Lrdal Ulla-Britt Jnsson Urban Sjqvist Lena Douhan Hkansson Per Venge Marie Carlson Department of Medical Sciences Clinical ChemistryUppsala University HospitalSE-75185 UppsalaSweden Division of Gastroenterology Department of Intestinal Medicinerebro University HospitalSE-70185 rebroSweden School of Health and Medical Sciences rebro UniversitySE-70185 rebroSweden IBD Clinical research group Karolinska University HospitalSE-17177 StockholmSweden Department for Clinical Science Intervention and TechnologyKarolinska University HospitalSE-17177 StockholmSweden Department of Medical Sciences Gastroenterology Research GroupUppsala UniversitySE-75185 UppsalaSweden Department of Medicine Karolinska InstitutetSE-17177 StockholmSweden

AIM： To study the association between inflammatory bowel disease （IBD） and genetic variations in eosinophil protein X （EPX） and eosinophil cationic protein （ECP）. METHODS： DNA was extracted from ethylene diamine tetraacetic acid blood of 587 patients with Crohn＇s disease （CD）, 592 with ulcerative colitis （UC） and 300 healthy subjects. The EPX405 （G 〉 C, rs2013109）, ECP434 （G 〉 C, rs2073342） and ECP562 （G 〉 C, rs2233860） gene polymorphisms were analysed, by the 5＇-nuclease allelic discrimination assay. For de- termination of intracellular content of EPX and ECP in granulocytes, 39 blood samples was collected and extracted with a buffer containing cetyltrimethylam- monium bromide. The intracellular content of EPX was analysed using an enzyme-linked immunosorbent as- say. The intracellular content of ECP was analysed with the UniCAP system as described by the manufacturer. Statistical tests for calculations of results were χ2 test, Fisher＇s exact test, ANOVA, Student-Newman-Keuls test, and Kaplan-Meier survival curve with Log-rank test for trend, the probability values of P 〈 0.05 were considered statistically ***： The genotype frequency for males with UC and with an age of disease onset of ≥ 45 years （n = 57） was for ECP434 and ECP562, GG = 37%, GC = 60%, CC = 4% and GG = 51%, GC = 49%, CC = 0% respectively. This was significantly different from the healthy subject＇s genotype frequencies of ECP434 （GG = 57%, GC = 38%, CC = 5%; P = 0.010） and ECP562 （GG = 68%, GC = 29%,CC = 3%; P = 0.009）. The genotype frequencies for females, with an age of dis- ease onset of ≥ 45 years with CD （n = 62）, was for the ECP434 and ECP562 genotypes GG = 37%, GC =52%, CC = 11% and GG = 48%, GC = 47% and CC = 5% respectively. This was also statistically different from healthy controls for both ECP434 （P = 0.010） and ECP562 （P = 0.013）. The intracellular protein concen- tration of EPX and ECP was calculated in μg/10^6 eosi- nophils and then correlated to the EPX 405 genotypes

关键词： Eosinophil derived neurotoxin RNase 2 RNase 3 Single nucleotide polymorphism Inflamma-tion bowel disease Crohn's disease Ulcerative colitis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：