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Involvement of GnRH and Gonadotropin Genes in Oocyte Development of Blue Gourami Females (<i>Trichogaster trichopterus</i>)

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Advances in Biological Chemistry 2014年第3期4卷 197-202页

作者： Gad Degani School of Science and Technology Tel-Hai Academic College Tel Hai Israel

The goal of this study was to gain a fundamental understanding of RnRH 1 and 3, as well as FSH and LH action, in ovarian follicles during oocyte growth by examining changes in ovarian gene transcription in blue gourami females (Trichogaster trichopterus). The levels of target ovarian mRNAs were determined by quantitative real-time PCR. GnRH1 mRNA levels were higher in oocytes at the previtellogenic stage compared to the vitellogenic and follicular oocytes maturation (FOM) stages. No significant differences in GnRH3 mRNA levels were detected among oocytes during the different stages of development. βLH and βFSH mRNA levels were lower in oocytes at the vitellogenic stage compared to the previtellogenic stage. The high transcription of GnRH 1 and 3 in the brain and of FSH and LH in the pituitary of blue gourami as was found in previous studies in our laboratory, compared to mRNA levels changed in ovary during oogenesis, supporting the hypothesis that differences exist between the function of endocrine and autocrine/paracrine of these hormones.

关键词： GnRH and Gonadotropin Genes Blue Gourami Females

Metal ion metabolism and osteoporosis:possible implications for pharmaceutical biotechnology and tissue engineering

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Science China(Life Sciences) 2024年第8期67卷 1763-1765页

作者： Huaqiang Tao Qiufei Wang Kai Chen Pengfei Zhu Ye Gu Dechun Geng Department of Orthopedics The First Affiliated Hospital of Soochow UniversitySuzhou 215000China Department of Orthopedics Changshu Hospital Affiliated to Soochow UniversityFirst People’s Hospital of Changshu CityChangshu 215506China Department of Orthopedics Hai’an People’s HospitalHai’an 226600China

Osteoporosis(OP)is a systemic metabolic bone disease characterized by low bone mass,damage to bone microstructure and increased bone *** imbalance of functional coupling between osteoblasts and osteoclasts contributes to the pathological progression of the disease(Rachner et al.,2011).The pathogenesis of OP is precisely controlled by the complex regulatory network of the bone *** elements,although present in small amounts in the body,are essential for their influence on the physiological activities of *** ions act as effective catalysts and have applications in all stages of cell biochemical evolution(Qian et al.,2021).Bone tissue contains various metal elements,and metal ions play indispensable roles in bone metabolism at the molecular and cellular levels(Luo et al.,2023).However,it is important to note that these metal ions can also contribute to the progression of OP by influencing multiple cellular pathways either directly or indirectly.

关键词： metabolism biotechnology indispensable

Primary pancreatic lymphoma: Report of six cases

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World Journal of Gastroenterology 2006年第31期12卷 5064-5067页

作者： hai Lin Shu-De Li Xian-Gui Hu Zhao-Shen Li Department of Gastroenterology Zhejiang Qu-Hua Hospital Quzhou 324004 Zhejiang Province China Department of Gastroenterology Changhai Hospital Second Military Medical University Shanghai 200433 China Department of Surgery Changhai Hospital Second Military Medical University Shanghai 200433 China

AIM： To heighten recognition of primary pancreatic lymphoma （PPL） in clinical practice. METHODS： A retrospective review of the clinical presentation, imaging characteristics and pathological features of PPL patients were presented, as well as their diagnosis and treatment, in combination with literature review. RESULTS： Histological diagnosis was made in four patients by surgery and in two patients by EUS-FNA. The six PPL patients （5 males and 1 female; age range, 16-65 years; mean age, 46 years） had the duration of symptoms for two weeks to three months. The primary presenting symptoms, though not characteristic, were abdominal pain, abdominal masses, weight loss, jaundice, nausea and vomiting. One of the patients developed acute pancreatitis. In one patient, the level of serum CA19-9 was 76.3 μg/L. Abdominal CT scan showed that three of the six tumors were located in the head of pancreas, two in the body and tail, and one throughout the pancreas. Diameter of the tumors in the pancreas in four cases was more than 6 cm, with homogeneous density and unclear borders. Enhanced CT scan showed that only the tumor edges were slightly enhanced. The pancreatic duct was irregularly narrowed in two cases whose tumors were located in the pancreatic head and body, in which endoscopic retrograde cholangiopancreatography （ERCP） showed that the proximal segment was slightly dilated. Two patients underwent Whipple operation, one patient underwent pancreatectomy, and another patient underwent operative biliary decompression. PPL was in stage Ⅰ E in 2 patients and in stage Ⅱ E in 4 patients according to the Ann Arbor classification system. The diagnosis of B-cell non-Hodgkin＇s lymphoma was made in all patients histopathologically. All six patients underwent systemic chemotherapy, one of whom was also treated with gamma radiometry. One patient died two weeks after diagnosis, two patients lost follow-up, two patients who received chemotherapy survived 49 and 37 mo, and the remaining pa

关键词： Pancreatic malignant tumor Lymphoma non-Hodgkin's lymphoma Diagnosis

Alkaloids from stems of Ervatamia yunnanensis

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Chinese Chemical Letters 2007年第6期18卷 697-699页

作者： Xin Gen Luo hai Sheng Chen Shuang Liang Mao Huang Wei Dong Xuan Li Jin College of Pharmacy Second Military Medical University Shanghai 200433 China Department of Pharmacy Guangzhou Military General Hospital Guangzhou 510010 China Center of New Drug Evaluation Institute of Basic Medical Sciences Second Military Medical University Shanghai 200433 China

Six indole alkaloids were isolated from the stems of Ervatamia yunnanensis. Among them, yunnanensine (I) is new. The other five are known alkaloids, namely: 19,20-E-vallesamine (II), 19s-heyneanine (III), ibogaine (IV... 详细信息

关键词： Ervatamia yunnanensis Indole alkaloids

The Nam hai,占婆古国的小小新诗

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缤纷 2009年第10期 102-105页

作者：黄梦斯 The Nam hai

会安古城,是享有美誉的旅行目的地,也是探访古老占婆文明的必经之地。古城内的旅舍客栈各具风情,论大气与格调,当属The Nam hai。

关键词：安古城占婆 The Nam hai 会安越南中部福布斯室内设计师南中国海二海发展时期

Quantum entanglement of the binomial field interacting with a cascade three-level atom beyond the rotating wave approximation

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Science China(Physics,Mechanics & Astronomy) 2011年第9期54卷 1625-1630页

作者： PEN XueZao CONG HongLu WANG XuWen XIA JianPing School of Science Southwest University of Science and Technology Mianyang 621010 China Physics Group Beijing Jiaotong University Hai Bin College Huanghua 061100 China

In this paper, the quantum entanglement between a single mode binomial field and a cascade three-level atom is calculated mechanically without the rotating wave approximation. The numerical results indicate that the quantum entanglement at the first few periods is reduced notably due to the fact that the atom is initially in the superposition state. With increasing field parameter 17, the period of the entanglement evolution becomes obvious and the quantum decoherence phenomenon emerges in a short time.

关键词： binomial state field quantum entanglement field entropy

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自适应量子储层计算与多任务学习

Science Bulletin 2023年第20期68卷 2321-2329,M0004页

作者：夏威邹杰邱型泽陈锋朱兵李春贺邓东灵李晓鹏 State Key Laboratory of Surface Physics Key Laboratory of Micro and Nano Photonic Structures(MOE)and Department of PhysicsFudan UniversityShanghai 200433China School of Physics Science and Engineering Tongji UniversityShanghai 200092China Institute of Science and Technology for Brain-Inspired Intelligence Fudan UniversityShanghai 200433China Hong Kong and Shang hai Banking Corporation Laboratory Hong Kong and Shang Hai Banking Corporation Holdings PLCGuangzhou 511458China Shanghai Center for Mathematical Sciences and School of Mathematical Sciences Fudan UniversityShanghai 200433China Center for Quantum Information IIISTsinghua UniversityBeijing 100084China Shanghai Qi Zhi Institute AI TowerShanghai 200232China Shanghai Research Center for Quantum Sciences Shanghai 201315China

随着实验技术的快速发展,含噪声的中等规模量子(NISQ)设备的可编程性越来越高,人们能够更好地利用量子计算的优势.本文利用可编程的NISQ设备的复杂动力学来进行量子储层计算,并通过使用遗传算法来优化该过程.令人惊讶的是,单个自适应量... 详细信息

随着实验技术的快速发展,含噪声的中等规模量子(NISQ)设备的可编程性越来越高,人们能够更好地利用量子计算的优势.本文利用可编程的NISQ设备的复杂动力学来进行量子储层计算,并通过使用遗传算法来优化该过程.令人惊讶的是,单个自适应量子储层可以同时学习多个任务,包括振荡型基因网络、混沌型基因网络和分数阶蔡氏电路.通过自适应量子储层计算,这些任务的学习性能得到了显著提升,远远超过了经典储层计算的表现.此外,本文还将自适应量子储层计算应用于外汇市场,相较于经典储层计算,它能更准确地捕捉汇率的随机演化.通过与经典储层计算的比较,本文突出了量子相干性在量子储层计算中的重要性,并验证了量子相干性是实现卓越学习性能的关键.研究结果表明,自适应量子储层计算能够充分发挥NISQ设备的量子计算能力,并在通用人工智能的发展方面具有巨大潜力.

关键词：基因网络多任务学习量子计算量子相干性 NIS 遗传算法蔡氏电路外汇市场

Study on application value of HBV DNA, AFP and GP73 in diagnosis of chronic hepatitis B severity and liver fibrosis

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Journal of hainan Medical University 2019年第9期25卷 62-65页

作者： hai-Lin Bao Qun Xie Department of Clinical Laboratory Hai'an Hospital of Traditional Chinese MedicineHai'an226600China Department of Infectious Diseases Hai'an People's HospitalHai'an226600China

Objective: To explore the application of hepatitis B virus (HBV) DNA, alpha-fetoprotein (AFP), and Golgi transmembrane glycoprotein 73 (GP73) in the diagnosis of chronic hepatitis B (CHB) severity and liver fibrosis. Methods: A total of 160 patients with CHB were selected from August 2017 to August 2018. The severity of the disease was classified into mild, moderate, severe and hepatic failure according to the standard of the guidelines for the prevention and treatment of chronic hepatitis B. Fibrosis was classified according to Masson staining, and S2-S4 was fibrosis. The 40 healthy persons in the same period were selected as the control group. The levels of HBV DNA, AFP, and GP73 in peripheral blood of all patients were detected. The healthy person in the same period was selected as the control group. Results: The levels of AFP and GP73 in CHB patients were significantly higher than those in the control group (P<0.05). And with the increase of severity, the levels of AFP and GP73 also increased significantly (P<0.05). With the increase of liver fibrosis in CHB patients, the levels of HBV DNA, AFP and GP73 were significantly increased (P<0.05). There was a significant positive correlation between the severity of AFP, GP73, and CHB and degree of fibrosis (P<0.05). There was a positive correlation between HBV DNA and fibrosis (P<0.05). The AUC of AFP and GP73 on the severity of CHB were 0.711 and 0.729, respectively. The AUC of HBV DNA, AFP, and GP73 on CHB liver fibrosis were 0.534, 0.745, and 0.758, respectively. Conclusions:AFP, GP73, and CHB are positively correlated with severity and fibrosis, and they have certain diagnostic value for CHB disease and fibrosis. HBV DNA also has a certain value for the degree of liver fibrosis in patients with CHB.

关键词： Chronic hepatitis B Hepatitis B virus Alpha fetoprotein Golgi transmembrane glycoprotein

CLINICAL APPLICATION OF ACUPOINT RENYING(ST 9)

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Journal of Traditional Chinese Medicine 1993年第3期13卷 205-206页

作者：仲跻尚 hai'an Country Hospital of Traditional Chinese Medicine Jiangsu Province 226600

Acupoint Renying(St 9)pertains to theStomach Channel of ***-cient physicians used to take the pulse herefor diagnosis of diseases of internal *** has shown that acupuncture at thispoint produces relief in many ***-ing... 详细信息

关键词： acupuncture relief organs proximity needle ST 9 sensation nausea laryngeal throat