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Direct Photolithography of WO_(x)Nanoparticles for High‑Resolution Non‑Emissive Displays

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Nano-Micro Letters 2025年第3期17卷 297-309页

作者： Chang Gu Guojian Yang Wenxuan Wang Aiyan Shi Wenjuan Fang Lei Qian Xiaofei Hu Ting Zhang Chaoyu Xiang Yu‑Mo Zhang Laboratory of Optoelectronic Information Technology and Devices Ningbo Institute of Materials Technology and EngineeringChinese Academy of SciencesNingbo 315201People’s Republic of China Hangzhou Bay Laboratory of Advanced Nano‑Optoelectronic Materials and Devices Qianwan Institute of CNITECHNingbo 315336People’s Republic of China Smart Materials for Architecture Research Lab Innovation Center of Yangtze River DeltaZhejiang UniversityJiaxing 314100People’s Republic of China University of Science and Technology of China Hefei 230026People’s Republic of China State Key Lab of Supramolecular Structure and Materials College of ChemistryJilin UniversityChangchun 130012People’s Republic of China

High-resolution non-emissive displays based on electrochromic tungsten oxides(WOx)are crucial for future near-eye virtual/augmented reality interactions,given their impressive attributes such as high environmental stability,ideal outdoor readability,and low energy ***,the limited intrinsic structure of inorganic materials has presented a significant challenge in achieving precise patterning/pixelation at the micron ***,we successfully developed the direct photolithography for WOx nanoparticles based on in situ photo-induced ligand *** strategy enabled us to achieve ultra-high resolution efficiently(line width3600 cycles),as well as promising applications in electronic logos,pixelated displays,flexible electronics,*** success and advancements presented here are expected to inspire and accelerate research and development(R&D)in high-resolution non-emissive displays and other ultra-fine micro-electronics.

关键词： Electrochromic Direct photolithography WOx nanoparticles In situ photo-induced ligand exchange High-resolution displays

Single-cell technologies: current and near future

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Science China Life Sciences 2025年第1期68卷 1-4页

作者： Chenfei Wang Qi Liu Xiaohui Fan Tieliu Shi Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration Ministry of EducationOrthopedics DepartmentTongji HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Frontier Science center for Stem Cells School of Life Sciences and TechnologyTongji University Translational Medical center for Stem Cell Therapy and Institute for Regenerative Medicine Shanghai East HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Research Institute of Intelligent Computing Zhejiang Lab Pharmaceutical Informatics Institute College of Pharmaceutical SciencesZhejiang University National Key Laboratory of Chinese Medicine Modernization Innovation Center of Yangtze River DeltaZhejiang University center for Bioinformatics and Computational Biology Shanghai Key Laboratory of Regulatory Biologythe Institute of Biomedical Sciences and School of Life SciencesEast China Normal University Key Laboratory of Advanced Theory and Application in Statistics and Data Science (MOE) School of StatisticsEast China Normal University

Single-cell technologies enable the indepth exploration of multiple biological hierarchies at the scale of individual cells,which have deepened our knowledge of cellular diversity, tissue organization, and overall organism function(Sun et al.,2024). In 2009, single-cell RNA sequencing(sc RNA-seq) was first developed as a powerful tool to dissect gene expression and uncover transcriptional *** the rapid advancement of technology, single-cell approaches have expanded to encompass other omics, such as genomics, epigenomics, proteomics,and metabolomics.

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Single-cell omics: experimental workflow, data analyses and applications

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Science China Life Sciences 2025年第1期68卷 5-102页

作者： Fengying Sun Haoyan Li Dongqing Sun Shaliu Fu Lei Gu Xin Shao Qinqin Wang Xin Dong Bin Duan Feiyang Xing Jun Wu Minmin Xiao Fangqing Zhao Jing-Dong J.Han Qi Liu Xiaohui Fan Chen Li Chenfei Wang Tieliu Shi Department of Clinical Laboratory the Affiliated Wuhu Hospital of East China Normal University (The Second People's Hospital of Wuhu City) Pharmaceutical Informatics Institute College of Pharmaceutical SciencesZhejiang University Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration (Tongji University) Ministry of EducationOrthopaedic DepartmentTongji HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Frontier Science center for Stem Cells School of Life Sciences and TechnologyTongji University Translational Medical center for Stem Cell Therapy and Institute for Regenerative Medicine Shanghai East HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Research Institute of Intelligent Computing Zhejiang Lab Shanghai Research Institute for Intelligent Autonomous Systems center for Single-cell Omics School of Public HealthShanghai Jiao Tong University School of Medicine National Key Laboratory of Chinese Medicine Modernization Innovation Center of Yangtze River DeltaZhejiang University center for Bioinformatics and Computational Biology Shanghai Key Laboratory of Regulatory Biologythe Institute of Biomedical Sciences and School of Life SciencesEast China Normal University Beijing Institutes of Life Science Chinese Academy of Sciences Peking-Tsinghua center for Life Sciences Academy for Advanced Interdisciplinary StudiesCenter for Quantitative Biology (CQB)Peking University Zhejiang Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases Women's HospitalZhejiang University School of Medicine Key Laboratory of Advanced Theory and Application in Statistics and Data Science-MOE School of StatisticsEast China Normal University

Cells are the fundamental units of biological systems and exhibit unique development trajectories and molecular features. Our exploration of how the genomes orchestrate the formation and maintenance of each cell, and control the cellular phenotypes of various organismsis, is both captivating and intricate. Since the inception of the first single-cell RNA technology, technologies related to single-cell sequencing have experienced rapid advancements in recent years. These technologies have expanded horizontally to include single-cell genome, epigenome,proteome, and metabolome, while vertically, they have progressed to integrate multiple omics data and incorporate additional information such as spatial sc RNA-seq and CRISPR screening. Single-cell omics represent a groundbreaking advancement in the biomedical field,offering profound insights into the understanding of complex diseases, including cancers. Here, we comprehensively summarize recent advances in single-cell omics technologies, with a specific focus on the methodology section. This overview aims to guide researchers in selecting appropriate methods for single-cell sequencing and related data analysis.

关键词： single-cell sequencing genome epigenome proteomics metabolomics multimodal spatial transcriptomics CRISPR screening

Degradation of dichloromethane by an isolated strain Pandoraea pnomenusa and its performance in a biotrickling filter

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Journal of Environmental Sciences 2014年第5期26卷 1108-1117页

作者： Jianming Yu Wenji Cai Zhuowei Cheng Jianmeng Chen Collaborative Innovation center of yangtze river delta Region Green Pharmaceuticals Zhejiang University of Technology College of Biological and Environmental Engineering Zhejiang University of Technology

A strain Pandoraea pnomenusa LX-1 that uses dichloromethane （DCM） as sole carbon and energy source has been isolated and identified in our laboratory. The optimum aerobic biodegradation of DCM in batch culture was evaluated by response surface methodology. Maximum biodegradation （5.35 mg/（***）） was achieved under cultivation at 32.8℃, pH 7.3, and 0.66% NaC1. The growth and biodegradation processes were well fitted by Haldane＇s kinetic model, yielding maximum specific growth and degradation rates of 0.133 hr^-1 and 0.856 hr^-1, respectively. The microorganism efficiently degraded a mixture of DCM and coexisting components （benzene, toluene and chlorobenzene）. The carbon recovery （52.80%-94.59%） indicated that the targets were predominantly mineralized and incorporated into cell materials. Electron acceptors increased the DCM biodegradation rate in the following order： mixed 〉 oxygen 〉 iron 〉 sulfate 〉 nitrate. The highest dechlorination rate was 0.365 mg C1-/（*** biomass）, obtained in the presence of mixed electron acceptors. Removal was achieved in a continuous biotrickling filter at 56%-85% efficiency, with a mineralization rate of 75.2%. Molecular biology techniques revealed the predominant strain as P. pnomenusa LX-1. These results clearly demonstrated the effectiveness of strain LX-1 in treating DCM-containing industrial effluents. As such, the strain is a strong candidate for remediation of DCM coexisting with other organic compounds.

关键词： dichloromethane Pandoraea pnomenusa biodegradation characteristics removal performance carbon balance

Exact solutions of non-Hermitian chains with asymmetric long-range hopping under specific boundary conditions

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Chinese physics B 2022年第1期31卷 81-86页

作者： Cui-Xian Guo Shu Chen Beijing National Laboratory for Condensed Matter physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100049China yangtze river delta physics Research center Liyang 213300China

We study the one-dimensional general non-Hermitian models with asymmetric long-range hopping and explore how to analytically solve the systems under some specific boundary *** the introduction of long-range hopping terms prevents us from finding analytical solutions for arbitrary boundary parameters,we identify the existence of exact solutions when the boundary parameters fulfill some constraint relations,which give the specific boundary *** analytical results show that the wave functions take simple forms and are independent of hopping range,while the eigenvalue spectra display rich model-dependent ***,we find the existence of a special point coined as pseudo-periodic boundary condition,for which the eigenvalues are the same as those of the periodical system when the hopping parameters fulfill certain conditions,whereas the eigenstates display the non-Hermitian skin effect.

关键词： non-Hermitian physics exact solution topological physics long-range hopping

One-pot Multicomponent Synthesis of Highly Functionalized 1,4-Dihydropyridines Using Porcine Pancreatic Lipase

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Chemical Research in Chinese Universities 2019年第2期35卷 235-238页

作者： JIANG Ling YE Wenting SU Weike Collaborative Innovation center of yangtze river delta Region Green Pharmaceuticals Zhejiang University of TechnologyHangzhou 310014P.R.China

A series of highly timctionalized 1,4-dihydropyridines was synthesized via one-pot multicomponent reactions of aromatic aldehyde,malononitrile and N-methyl-1-(methylthio)-2-nitroethenamine using Porcine pancreatic lipase(PPL)as catalyst in *** protocol is featured by mild reaction conditions,simple operation and environmental acceptability.

关键词： Porcine pancreatic lipase Biocatalysis One-pot synthesis High functionalized 1,4-dihydropyridines

Recent advances of small-molecule fluorescent probes for detecting biological hydrogen sulfide

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Frontiers of Chemical Science and Engineering 2022年第1期16卷 34-63页

作者： Lei Zhou Yu Chen Baihao Shao Juan Cheng Xin Li Collaborative Innovation center of yangtze river delta Region Green Pharmaceuticals Zhejiang University of TechnologyHangzhou 310014China College of Pharmaceutical Sciences Zhejiang UniversityHangzhou 310058China

H_(2)S is well-known as a colorless,acidic gas,with a notoriously rotten-egg *** was recently revealed that H_(2)S is also an endogenous signaling molecule that has important biological functions,however,most of its physiology and pathology remains ***,the enthusiasm for H_(2)S research *** imaging technology is an important tool for H_(2)S biology *** development of fluorescence imaging technology has realized the study of H_(2)S in subcellular organelles,facilitated by the development of fluorescent *** probes reviewed in this paper were categorized according to their chemical mechanism of sensing and were divided into three groups:H_(2)S reducibility-based probes,H_(2)S nucleophilicity-based probes,and metal sulfide precipitation-based *** structure of the probes,their sensing mechanism,and imaging results have been discussed in ***,we also introduced some probes for hydrogen polysulfides.

关键词： hydrogen sulfide fluorescent probe reducibility nucleophilicity copper sulfide precipitate hydrogen polysulfides

High-Pressure Synthesis and Thermal Transport Properties of Polycrystalline BAs_x

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Chinese physics Letters 2020年第6期37卷 53-56页

作者： Lei Gao Qiulin Liu Jiawei Yang Yue Wu Zhehong Liu Shijun Qin Xubin Ye Shifeng Jin Guodong Li Huaizhou Zhao Youwen Long Beijing National Laboratory for Condensed Matter physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100049China State Key Laboratory of Heavy Oil Processing College of New Energy and MaterialsChina University of PetroleumBeijing 102249China yangtze river delta physics rearch center Liyang 213300China Songshan Lake Materials Laboratory Dongguan 523808China

Polycrystalline BAsx(x=0.80-1.10)compounds with different boron-to-arsenic elemental molar ratios were synthesized by a high-pressure and high-temperature sintering *** with other ambient-pressure synthesis methods,high pressure can significantly promote the reaction speed as well as the reaction *** the content of arsenic increases from x=0.91 to 1.10,the thermal conductivity of BAsx gradually increases from 53 to 65 W·m-1·***,the temperature dependence of thermal conductivities of these samples reveals an Umklapp scattering due to the increasing phonon *** work provides a highly efficient method for polycrystalline BAs synthesis.

关键词： synthesis. method. arsenic

The Centenary of the CPC:Evolving Economic Development Thought for New China

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China Economist 2021年第6期16卷 42-58页

作者： Hong Yinxing yangtze river delta Economics and Social Development Research center School of EconomicsNanjing UniversityNanjingChina

After the founding of People’s Republic of China in 1949,the economic development philosophies of the Communist Party of China(CPC)evolved over *** of this difficult journey of ideological change can not only shed light on the origin,but also better understand the theoretical contributions of Xi Jinping thought on China’s socialist economy in the new *** paper investigates China’s evolving economic development thoughts from six dimensions in three eras when the Chinese nation(i)independently established a basic industrial system from a blank sheet,(ii)sought prosperity through reform and opening up,and(iii)increased national *** six dimensions of this study include:(i)the tasks identified by the Party as essential for various stages of development;(ii)the different modes of economic development embraced based on development thoughts for various stages;(iii)the different modernization pathways to achieve the goals of socialist modernization;(iv)the adjustment of agricultural policy and development paths to close the urban-rural divide;(v)the different approaches for regulating the supply side and demand side of economic development with the emphasis changing across various stages;and(vi)the different emphasis to internal and external economic circulations across various stages.

关键词： New China the Communist Party of China economic development thoughts evolution