Single-cell technologies: current and near future

作     者：Chenfei Wang Qi Liu Xiaohui Fan Tieliu Shi 

作者机构：Key Laboratory of Spine and Spinal Cord Injury Repair and RegenerationMinistry of EducationOrthopedics DepartmentTongji HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Frontier Science Center for Stem CellsSchool of Life Sciences and TechnologyTongji University Translational Medical Center for Stem Cell Therapy and Institute for Regenerative MedicineShanghai East HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Research Institute of Intelligent ComputingZhejiang Lab Pharmaceutical Informatics InstituteCollege of Pharmaceutical SciencesZhejiang University National Key Laboratory of Chinese Medicine ModernizationInnovation Center of Yangtze River DeltaZhejiang University Center for Bioinformatics and Computational BiologyShanghai Key Laboratory of Regulatory Biologythe Institute of Biomedical Sciences and School of Life SciencesEast China Normal University Key Laboratory of Advanced Theory and Application in Statistics and Data Science (MOE)School of StatisticsEast China Normal University 

出 版 物：《Science China Life Sciences》 (中国科学:生命科学(英文版))

年 卷 期：2025年第68卷第1期

页      面：1-4页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 071009[理学-细胞生物学] 09[农学] 0901[农学-作物学] 090102[农学-作物遗传育种] 

摘      要：Single-cell technologies enable the indepth exploration of multiple biological hierarchies at the scale of individual cells,which have deepened our knowledge of cellular diversity, tissue organization, and overall organism function(Sun et al.,2024). In 2009, single-cell RNA sequencing(sc RNA-seq) was first developed as a powerful tool to dissect gene expression and uncover transcriptional *** the rapid advancement of technology, single-cell approaches have expanded to encompass other omics, such as genomics, epigenomics, proteomics,and metabolomics.