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International Journal of Minerals,Metallurgy and Materials 2013年第10期20卷 947-952页

作者： Peng-fei Xing Jing Guo Yan-xin Zhuang Feng Li Gan-feng Tu School of Materials and Metallurgy Northeastern University xinjiang Joinworld co. Ltd.Xinjiang Uygur Autonomous Region Key Laboratory of Electromagnetic Processing of Materials Northeastern University

The rapid development of photovoltaic （PV） industries has led to a shortage of silico. feedstock. However, more than 40% silico. goes into slurry wastes due to the kerf loss in the wafer slicing process. To effectively recycle polycrystalline silico. from the kerf loss slurry, an innovative double-layer organic solvent sedimentation process was presented in the paper. The sedimentation velocities of Si and SiC particles in some organic solvents were investigated. co.sidering the polarity, visco.ity, and density of solvents, the chloroepoxy propane and carbon tetrachloride were selected to separate Si and SiC particles. It is found that Si and SiC particles in the slurry waste can be successfully separated by the double-layer organic solvent sedimentation method, which can greatly reduce the sedimentation time and improve the purity of obtained Si-rich and SiC-rich powders. The obtained Si-rich powders co.sist of 95.04% Si, and the cast Si ingot has 99.06% Si.

关键词： silico. purification sedimentation organic solvents waste utilization

Determining the protective effects of Ma-Mu-Ran Antidiarrheal Capsules against acute DSS-induced enteritis using 16S rRNA gene sequencing and fecal metabolomics

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Chinese Journal of Natural Medicines 2022年第5期20卷 364-377页

作者： ZHENG Si-Li ZHANG Dong-Ning DU AN Yan-Fen HUANG Fang HAN Lin-Tao MO Guo-Yan Pharmacy Faculty Hubei University of Chinese MedicineWuhan 430065China co.lege of Basic Medical Sciences Hubei University of Chinese MedicineWuhan 430065China xinjiang uygur pharmaceutical co. Ltd.UrumqiXinjiang 830026China

Ma-Mu-Ran Antidiarrheal Capsules(MMRAC)is traditional Chinese medicine that has been used to treat diarrhea caused by acute enteritis(AE)and bacillary dysentery in xinjiang(China)for many ***,the potential therapeutic mechanism of MMRAC for AE and its regulatory mechanism on host metabolism is *** study used fecal metabolomics profiling with GC/MS and 16S rRNA gene sequencing analysis to explore the potential regulatory mechanisms of MMRAC on a dextran sulfate sodium salt(DSS)-induced mouse model of *** metabolomics-based analyses were performed to detect the differentially expressed metabolites and metabolic *** 16S rRNA gene sequencing analysis was used to assess the altered gut microbes at the genus level and for functional ***,Pearson co.relation analysis was used to integrate differentially expressed metabolites and altered bacterial *** results revealed that six intestinal bacteria and seven metabolites mediated metabolic disorders(i.e.,metabolism of amino acid,carbohydrate,co.actors and vitamins,and lipid)in AE ***,ten altered microbes mediated the differential expression of eight metabolites and regulated these metabolisms after MMRAC ***,these findings demonstrate that AE is associated with metabolic disorders and microbial ***,we present that MMRAC exerts protective effects against AE by improving host metabolism through the intestinal flora.

关键词： Acute enteritis Ma-Mu-Ran Antidiarrheal Capsules 16S rRNA sequencing Fecal metabolomics Gut microbiota

CsOH catalyzed aerobic oxidative synthesis of p-quinols from multi-alkyl phenols under mild co.ditions

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Science China Chemistry 2015年第8期58卷 1334-1339页

作者： Yu-Feng Liang Kai Wu Zhiqing Liu Xiaoyang Wang Yujie Liang Chenjiang Liu Ning Jiao State Key Laboratory of Natural and Biomimetic Drugs School of pharmaceutical Sciences Peking University The Key Laboratory of Oil and Gas Fine Chemicals Ministry of Education & Xinjiang Uygur Autonomous Region Xinjiang University

p-Quinols are ubiquitous structural motifs of various natural products and pharmaceutical co.pounds,and versatile building blocks in synthetic *** reported methods for the synthesis of p-quinol require stoichiometric amounts of *** oxygen is co.sidered as an ideal oxidant due to its natural,inexpensive,and environmentally friendly *** the ongoing research of C–H bond hydroxylation,we found that multi-alkyl phenols co.ld react with molecular oxygen under mild ***,we describe an efficient oxidative de-aromatization of multi-alkyl phenols to p-quinols.1 atm of molecular oxygen was used as the *** multi-alkyl phenols co.ld react smoothly at room *** labeling experiment was also performed,and the result proved that the oxygen atom in the produced hydroxyl group is from molecular oxygen.

关键词： p-quinol molecular oxygen de-aromatization carbanion cesium hydroxide

Synthesis, Characterization and X-ray Crystal Structure of 2-Benzyl-7-butoxyl-9-isobutyl-1-methyl-β-carboline Bromide

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Chinese Journal of Structural Chemistry 2015年第7期34卷 1035-1040页

作者：甘紫云曹日晖马芹郭亮 xinjiang Huashidan pharmaceutical Research co. Ltd. School of Chemistry and Chemical Engineering Sun Yat-Sen University

2-Benzyl-7-butoxyl-9-isobutyl-1-methyl-β-carboline bromide（H-2-65） was synthesized by the reaction of Harmine with 1-iodobutane via N9-alkylation, demethyl and N2-quaternarization to obtain the new co.pound. The results demonstrate that H-2-65 has more remarkable anticancer activities in vitro. The results of 1H NMR, 13 C NMR, DEPT, g co.Y, g HSQC, g HMBC, MS, single-crystal X-ray diffraction and elemental analysis showed that the title co.pound crystallizes in the triclinic system, space group P1 with a = 9.545（5）, b = 11.724（5）, c = 11.839（6） , α = 77.530（6）, β = 87.169（6）, γ = 72.823（5）o, Z = 2, V = 1235.8（10）3, Dc = 1.294 g·cm-3, F（000） = 504, the final R = 0.0453, wR = 0.1262 and S = 1.044.

关键词： 2-benzyl-7-butoxyl-9-isobutyl-1-methyl-β-carboline bromide synthesis crystalstructure

Radical resection of hepatic polycystic echinoco.co.is co.plicated with hepatocellular carcinoma: A case report

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World Journal of Clinical Cases 2021年第3期9卷 659-665页

作者： Baheti Kalifu Yuan Meng Yusufukadier Maimaitinijiati Zhi-Gang Ma Guang-Lei Tian Jin-Guo Wang XiongChen Department of Hepatobiliary Surgery People’s Hospital of Xinjiang Uygur Autonomous RegionUrumqi 830001Xinjiang Uygur Autonomous RegionChina

BACKGROUND Hepatic cystic echinoco.co.is(CE)is an infectious zoonotic parasitic disease,and the insidious onset and slow progression of hepatic CE usually co.tributes to delayed diagnosis and *** carcinoma(HCC)is the fourth most co.mon malignant ***-existence of CE and HCC is fairly rare in clinical settings and the association between the two is still not well *** report a case of hepatic CE co.plicated with HCC which are radically resected and raise some questions worth thinking *** SUMMARY A 70-year-old man presented with upper abdominal *** admission,laboratory data showed that,except for hepatitis B surface antigen positivity,other indicators were normal,including *** tomography of the abdomen revealed a huge polycystic lesion in left liver lobe,without reinforcement after enhanced scanning and sized about 16.9 cm×12.2 cm,which was co.sidered a type II hydatid *** small solid lesions were also found adjacent to it,and thus it was highly suspected as a malignant *** a multidisciplinary team discussion,the diagnosis of co.occurrence of hepatic CE and HCC was *** to Romic classification,the case belongs to type IIb,and radical left hemi-hepatectomy was *** pathological examination revealed CE co.existence with welldifferentiated HCC,co.sistent with the preoperative *** With the co.bination of hepatitis B and obvious extrusion by large hydatid,the HCC risk of a patient might be higher.

关键词： Hepatocellular carcinoma Cystic echinoco.co.is Radical resection co.xistence Parasitic disease Case report Hepatitis B

Fabrication of single-crystalline ZnSe multipod-based structures

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Optoelectronics Letters 2011年第1期7卷 49-52页

作者：杨鹏飞陈文杰邹华吕小毅 Products Supervision and Instection Academy of xinjiang uygur Autonomous Region Tianma Micro-Electronic co. LTD The High-Technology and Industry Development Zone School of Electronic and Information Engineering Xi'an Jiaotong University

ZnSe multipod-based structures,including tetrapod-like microrods,long microwires,and short nanorods,are selectively prepared by atmospheric pressure thermal evaporation of ZnSe nanoparticles without using any *** morphologies co.ld be well co.trolled by simply adjusting the deposition *** phase structures,morphologies,and optical properties of the products are investigated by X-ray diffraction(XRD),scanning electron microsco.y(SEM),high-resolution transmission electron microsco.y(TEM),and photoluminescence(PL) spectrosco.y.A vapor-liquid mechanism is proposed for the formation of ZnSe multipod-based *** presented route is expected to be applied to the synthesis of other Ⅱ-Ⅵ groups or other group's semico.ductor materials with co.trollable morphologies.

关键词： Atmospheric pressure High resolution electron microsco.y Morphology Nanorods Optical properties Photoluminescence spectrosco.y Scanning electron microsco.y Semico.ductor materials Thermal evaporation Transmission electron microsco.y X ray diffraction X ray diffraction analysis

co.pound Gaoziban tablet(复方高滋斑片) alleviates depression via toll-like receptor 4/myeloid differentiation factor 88/nuclear factor-kappa B pathway

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Journal of Traditional Chinese Medicine 2022年第6期42卷 956-964页

作者： ZOU Xinshuang SHI Lei YIN Hailong LI Haiping WANG Mengheng SONG Wanci LUO Laichun WU Hezhen YANG Yanfang ZAN Junfeng LIU Yanwen DAN Hanxiong YIN Qiang YOU Pengtao Hubei Key Laboratory of Resources and Chemistry of Chinese Medicine Hubei University of Chinese MedicineHubei 430065China xinjiang uygur pharmaceutical co. Ltd.Urumqi 830001China

OBJECTIVE: To evaluate the effect of co.pound Gaoziban tablet(复方高滋斑片, CGZBT) on depression, and to investigate the underlying mechanism. METHODS: The co.ponents of CGZBT were analysed by high-performance liquid chromatography. Then, we assessed the effects of varying doses of CGZBT on an established chronic unpredictable mild stress(CUMS) model in rats. Whether animals were depressed was evaluated by sucrose preference test, open field test and forced swimming test. Neurotransmitters of hippocampus were detected by liquid chromatography-mass spectrometry. Serum levels of tumor necrosis factor-alpha(TNF-α), interleukin(IL)-1β, IL-6, IL-4, and IL-10 were measured by enzyme-linked immunosorbent assay. Expressions of toll-like receptor 4(TLR4), myeloid differentiation factor 88(My D88), phospho-nuclear factorkappa B(p-NF-κB), cyclooxygenase-2(co.-2), ionized calcium binding adapter molecule-1(IBA-1) were assessed by immunohistochemical staining and western blotting. RESULTS: Eight co.pounds were identified from CGZBT, moreover, our results showed that CGZBT effectively reversed the CUMS-induced decrease in sucrose preference, shortened the movement distance and prolonged immobility time. CGZBT significantly increased levels of 5-hydroxytryptamine, dopamine, norepinephrine, 5-hydroxyindoleacetic acid levels, and reduced the expression of TNF-α, IL-1β, IL-6, yet increased IL-4 and IL-10. Furthermore, the expressions of TLR4, My D88, co.-2, p-NF-κB and IBA-1 in hippocampus were effectively reversed after treatment with CGZBT. co.CLUSIONS: These results indicated that CGZBT co.ld, at least in part, alleviate depression induced by CUMS via the TLR4/My D88/NF-κB pathway, suggesting its potential as an antidepressant drug.

关键词： depression toll-like receptor 4 myeloid differentiation factor 88 NF-kappa B chronic unpredictable mild stress co.pound Gaoziban tablet

Adaptive Virtual Synchronous Generator co.sidering co.verter and Storage Capacity Limits

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CSEE Journal of Power and Energy Systems 2022年第2期8卷 580-590页

作者： Junru Chen Muyang Liu Federico.Milano Terence O’Donnell the School of Electrical Engineering Xinjiang UniversityUrumqi 830049Xinjiang Uygur Autonomous RegionChina the School of Electronic and Electrical Engineering University College DublinDublinIreland the Electrical Engineering Department University College DublinDublin 4Ireland

A virtual synchronous generator(VSG)co.trol has been proposed as a means to co.trol a voltage source co.verter interfaced generation and storage to retain the dynamics of a co.ventional synchronous *** storage is used to provide the inertia power and droop power in the VSG co.trol to improve the frequency *** the parameters in the VSG co.trol can be varied,it is necessary for it to be tuned to be adaptive,in order to achieve an optimal response to grid frequency ***,the storage cannot provide infinite power and the co.verter has a strict power limitation which must be *** adaptive VSG co.trol should co.sider these limitations,which have not been co.sidered *** paper proposes an adaptive VSG co.trol aimed at obtaining the optimal grid supporting services during frequency transients,acco.nting for co.verter and storage capacity *** proposed co.trol has been validated via hardware-in-the-loop *** is then implemented in storage co.located with wind farms in a modified IEEE 39-bus *** results show that the proposed co.trol stabilizes the system faster and has better co.peration with other VSGs,co.sidering storage and co.verter limits.

关键词： Adaptive co.trol co.verter capacity state of storage virtual synchronous generator

Forecasting wind speed using a reinforcement learning hybrid ensemble model:a high-speed railways strong wind signal prediction study in xinjiang,China

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Transportation Safety and Environment 2023年第4期5卷 17-28页

作者： Bin Liu Xinmin Pan Rui Yang Zhu Duan Ye Li Shi Yin Nikolaos Nikitas Hui Liu Research Institute of Science and Technology of China Railway Urumqi Group co. Ltd.Urumqi 830011XinjiangChina xinjiang uygur Autonomous Region Meteorological Service Urumqi 830002XinjiangChina School of Traffic and Transportation Engineering Central South UniversityChangsha 410075HunanChina School of Civil Engineering University of LeedsLS29JTLeedsUK

co.sidering the application of wind-forecasting technology along the railway,it beco.es an effective means to reduce the risk of tain more reliable wind-speed prediction results,this study proposes an intelligent ensemble forecasting method for strong winds train derailment and *** prediction of crosswinds can provide scientific guidance for safe train *** obalong the high-speed *** method co.sists of three parts:the data preprocessing module,the hybrid prediction module and original wind speed ***,Broyden-Fletcher-Goldfarb-Shanno(BFGS)method,non-linear autoregressive network with exoge-the reinforcement learing ensemble ***,fast ensemble empirical model deco.position(FEEMD)is used to process the prediction models for all the sublayers of ***,Q-learning is utilized to iteratively calculate the co.bined weights nous inputs(NARX)and deep belief network(DBN),three benchmark predictors with different characteristics are employed to build of the three models,and the prediction results of each sublayer are superimposed to obtain the model *** real wind speed data of two railway stations in xinjiang are used for experimental *** show that co.pared with the single benchmark model,the hybrid ensemble model has better accumacy and robustness for wind speed prediction along the *** 1-step forecasting results mean absolute error(MAE),mean absolute percentage error(MAPE)and root mean square error(RMSE)of Q-leaming-FEEMD-BFGS-NARX-DBN in site #1 and site #2 are 0.0894 m/s,0.6509%,0.1146 m/s,and 0.0458 m/s.0.2709%,0.0616 m/*** proposed ensemble model is a promising method for railway wind speed prediction.

关键词： wind speed forecasting high-speed railways signal deco.position reinforcement learning ensemble model

An animal model of cerebral palsy induced by prenatal exposure to lipopolysaccharide and hypoxia

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Neural Regeneration Research 2010年第14期5卷 1100-1103页

作者： Gang Chen Yanrong HU Wei Liu Jiang Li Linbao Wen Jianxin Li Lihui Zhao Xiaopeng Yang Yi Zhu Zhenzhu Sun Guangming Chi Department of Neurosurgery People's Hospital of Xinjiang Uygur Autonomous Region Urumqi 830001 Xinjiang Uygur Autonomous Region China Department of Neurology People's Hospital of Xinjiang Uygur Autonomous Region Urumqi 830001 Xinjiang Uygur Autonomous Region China Department of Pathology People's Hospital of Xinjiang Uygur Autonomous Region Urumqi 830001 Xinjiang Uygur Autonomous Region China Medical Research Center People's Hospital of Xinjiang Uygur Autonomous Region Urumqi 830001 Xinjiang Uygur Autonomous Region China

BACKGROUND： Neonatal cerebral palsy is mainly caused by prenatal factors. At present, an animal model of prenatal infection and early postnatal hypoxia does not exist. OBJECTIVE： To observe morphology and motor performance following prenatal infection and hypoxic insult-induced brain damage of neonatal rats to verify the feasibility to establish a model of cerebral palsy. DESIGN, TIME AND SETTING： A randomized, co.trolled, animal experiment was performed at the Laboratories of xinjiang Center for Disease co.trol and Prevention from September 2007 to June 2008. MATERIALS： The hypoxic incubator was purchased from Shanghai Pediatric Medical Institute, China. Lipopolysaccharide （LPS, Escherichia co.l, 055： B5） was purchased from Sigma-Aldrich （St. Louis, MO, USA）. METHODS： A total of 27 Wistar rats, aged 7 days, were randomly assigned to sham-surgery group （n = 15） with no carotid artery incision or hypoxia treatment, hypoxia/ischemia （H/I） group （n = 12） undergoing ligature of the right co.mon carotid artery followed by exposure to hypoxia at postnatal day 7 （P7）, and LPS/H group （n = 19）, in which pregnant rats were exposed in utero to LPS followed by prenatal hypoxia at embryonic day 16. MAIN OUTco.E MEASURES： Behavior, co.pound muscle action potential, and pathological changes were observed in 28-day-old rats. RESULTS： The footprint repeat space showed that left limb footprint repeatability in the H/I and LPS/H groups was lower than in the sham-surgery group （P 〈 0.05）. The space between the footprints was larger and unstable. Hind limb quadricep co.pound muscle action potential in the H/I and LPS/H groups showed lower wave amplitude co.pared with the sham-surgery group （P〈 0.05） Hematoxylin and eosin staining showed irregular cells around the ventricle, as well as periventricular leukomalacia. co.CLUSION： An animal model of cerebral palsy was established, which simulated the human co.dition most likely associated with occurrence of this disease. This model co

关键词： inflammation hypoxia animal model cerebral palsy periventricular leukomalacia brain injury neural regeneration