检索结果-南通市图书馆

维普期刊数据库

Probiotic bacteria attenuates cisplatin-induced nephrotoxicity through modulation of oxidative stress, inflammation and apoptosis in rats

在线全文

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Biomedicine 2019年第3期9卷 116-122页

作者： Emin Sengul Sevda Ur?ar Gelen Serkan Y?ld?r?m Fikret ?elebi Ali ??nar Department of Physiology Faculty of Veterinary Ataturk University Department of Food hygiene and Technology Faculty of Veterinary Ataturk University Department of Pathology Faculty of Veterinary Ataturk University

Objective: To investigate the effects of probiotic bacteria on cisplatin(CP)-induced nephrotoxicity. Methods: In the present study, 50 Sprague-Dawley rats were used and randomly divided into five groups including control, CP, probiotic bacteria treatment groups with different doses(0.5 and 1 mL) and only probiotic bacteria group. After CP and probiotic administration on seven days, rats sacrificed under anesthesia on the eighth day. The serum urea, creatinine, and blood urea nitrogen levels were analyzed. In renal tissue, malondialdehyde levels, superoxide dismutase and glutathione activity, interleukin-8, interleukin-1β and tumor necrosis factor-alpha levels were determined and histopathological and immunohistochemical changes were also examined. Results: According to results, urea, creatinine and blood urea nitrogen levels as well as kidney weights increased in CP group. Also, CP induced inflammation, oxidative stress, DNA damage and apoptosis in kidney tissue and caused histopathological changes. Administration of the high dose of probiotic bacteria could prevent these changes and damages. Conclusions: This study reveals that probiotic bacteria has protective effects on CP-induced renal damage in rats.

关键词： Apoptosis Cisplatin Nephrotoxicity Probiotic Rat

From mice to humans:a need for comparable results in mammalian neuroplasticity

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第2期20卷 464-466页

作者： Marco Ghibaudi Enrica Boda Luca Bonfanti Neuroscience Institute Cavalieri Ottolenghi OrbassanoItaly Department of veterinary Sciences University of TurinTurinItaly Department of Neuroscience Rita Levi-Montalcini University of TurinTurinItaly

Brain plasticity-A universal tool with many variations:The study of brain plasticity has been gaining interest since almost a century and has now reached a huge amount of information(>80,000 results in PubMed).Overall,different types of plasticity,including stem cell-driven genesis of new neurons(adult neurogenesis),cells in arrested maturation(dormant neurons),neuro-glial and synaptic plasticity,can coexist and contribute to grant plastic changes in the brain,from a cellular to system level(Benedetti and Couillard-Despres,2022;Bonfanti et al.,2023).

关键词： plasticity al. arrest

维普期刊数据库

Changes in expression of inhibitory substances in the intramural neurons of the stomach following streptozotocininduced diabetes in the pig

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2017年第33期23卷 6088-6099页

作者： Michal Bulc Katarzyna Palus Lukasz Zielonka Magdalena Gajecka Jaroslaw Całka Department of Clinical Physiology Faculty of veterinary Medicine University of Warmia and Mazury Department of veterinary Prevention and Feed hygiene Faculty of Veterinary MedicineUniversity of Warmia and Mazury in Olsztyn

AIM Influence of chronic hyperglycemia on chemical coding of enteric neurons in stomach using pig as a model for human diabetic *** Ten pigs were divided into two groups: diabetic(D group,n = 5) and control(C group,n = 5). Pigs constituting the experimental group were given streptozotocin(150 mg/kg). Animals were euthanized six weeks after the induction of diabetes. The samples of stomach were collected from animals of both groups. The cryostat sections were processed for double immunofluorescence staining using primary antisera directed towards pan-neuronal marker(Hu C/D) proteins and/or neuronal isoform of nitric oxide synthase(n NOS),vasoactive intestinal peptide(VIP) and galanin(GAL). RESULTS In the control group in the myenteric ganglia(MG) of the corpus we have noted 22.28% ± 1.19% of n NOS positive neurons,while in diabetic group we have found 40.74% ± 2.22% of n NOS immunoreactive perikarya(increase by 82.85 %). In turn in the pylorus we have observed 15.91% ± 0.58% n NOS containing neurons in control animals and 35.38% ± 1.54% in the diabetes group(increase by 122.37%). In the MG of the antrum and submucosal ganglion(SG) in the corpus hyperglycemia did not cause statistically significant changes. With regard to VIP-positive cell bodies in the antrum MG in the control animals we have noted 18.38 ± 1.39% and 40.74% ± 1.77% in the experimental group(increase by 121.65%). While in the corpus we have observed 23.20% ± 0.23% in the control and 30.93% ± 0.86% in the diabetes group(increase by 33.31%). In turn in the pylorus VIP positive cells bodies constituted 23.64% ± 1.56% in the control group and 31.20% ± 1.10% in the experimental group(increase by 31.97%). In the submucosal ganglion in the corpus we have noted 43.61% ± 1.06% in the control animals and 37.00% ± 1.77% in the experimental group(decrease by 15.15%). Expression of GAL-positive perikarya showed statistically significant changes only in the MG of the antrum and pylorus. In the antr

关键词： Immunohistochemistry Inhibitory neurons Streptozotocin Hyperglycemia Pig

Diversity of livestock associated methicillin-resistant Staphylococcus aureus

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Medicine 2017年第9期10卷 929-931页

作者： Henok A.Tegegne Ivana Kolackova Renata Karpískova Department of Bacteriology Veterinary Research InstituteBrnoCzech Republic Faculty of veterinary hygiene and Ecology University of Veterinary and Pharmaceutical Sciences BrnoCzech Republic

Objective: To evaluate the diversity and molecular characteristics of livestock associated methicillin-resistant Staphylococcus aureus in livestock animals, food of animal origin and the environment in the Czech ***: After having been primarily enriched in buffered peptone water, the samples were cultured on Baird–Parker agar. Presumptive colonies were sub-cultured to blood agar and assessed morphologically. Furthermore, presumptive Staphylococcus aureus colonies were confirmed by MALDI-TOF. Multiplex PCR, spa-typing, and MLST have been used to characterize the strains. Each mec A-positive Staphylococcus aureus isolates were examined against 14 different antimicrobials by using disk diffusion ***: In this study, 13 different spa-types belonging to five sequence types(ST) were detected. Ninety four percent of tested strains belonged to CC/ST398 for which t011,t034, t2123 and t2346 were the vast major spa-types. In addition, non-ST398 clones such as CC1(t127), ST5(t3598), ST8(t064) and ST361(t315) were detected, which are known as human associated ***: The diversity of livestock associated methicillin-resistant Staphylococcus aureus has grown, and detecting lineages of human origin in animals and vice-versa becomes more common. Thus, livestock animal and its products will be a potential for the evolvement of methicillin-resistant Staphylococcus aureus in human *** of pigs as well as other food-producing animal species and their products is therefore recommended.

关键词： CC398 MLST PCR Spa-typing

High-solids anaerobic mono-digestion of riverbank grass under thermophilic conditions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2017年第2期29卷 29-38页

作者： Fetra J.Andriamanohiarisoamanana Nobuyuki Matsunami Takaki Yamashiro Masahiro Iwasaki Ikko Ihara Kazutaka Umetsu Graduate School of Animal and Food hygiene Obihiro University of Agriculture and Veterinary Medicine Graduate School of Agriculture Science Kobe University

The purpose of this study was to investigate the potential of high-solids anaerobic mono-digestion of riverbank grass under thermophilic conditions, focusing on the effects of the strength and the amount of inoculum. Ensiled grass was inoculated with three different inocula; inoculum from liquid anaerobic digester（LI）, inoculum from dry anaerobic digester（DI）, and mixture of LI and DI（MI）, at feedstock-to-inoculum ratio（FIR） of 1, 2 and 4. The ensiling process of riverbank grass reduced moisture content（p 〉 0.05）, while the hemicellulose content was significantly increased from 30.88% to 35.15%（p 〈 0.05）, on dry matter basis. The highest methane production was at an FIR of 2 with MI（167 L/kg VSadded）,which was significantly higher（p 〈 0.05） than with DI, but not significant compared to LI（p 〉 0.05）. At an FIR of 4, digesters inoculated with LI and DI failed to produce methane,whereas 135 LCH4/kg VSaddedwas obtained with MI. The kinetic studies showed that at an FIR of 1 with LI and MI, the inoculum had less of effects on the hydrolysis rate constant（0.269 day-1and 0.245 day-1） and methane production（135 versus 149 L/kg VSadded）; rather,it affected the lag phase. In a thermophilic HS-AD of riverbank grass, the mixture of inoculum with low and high total solids content（TS） helps increase the TS of inoculum and digestion process. An FIR of 2 was deducted to be the limit for a better startup time and higher volumetric productivity of methane.

关键词： Riverbank grass High-solids anaerobic digestion Inoculum Feedstock-to-inoculum ratio Thermophilic temperature

维普期刊数据库

Two perspectives of Listeria monocytogenes hazards in dairy products:the prevalence and the antibiotic resistance

在线全文

学校读者我要写书评

暂无评论

Food Quality and Safety 2019年第4期3卷 233-241页

作者： Beyza H.Ulusoy Kefyalew Chirkena Faculty of veterinary Medicine Department of Food Hygiene and TechnologyNear East UniversityNicosiaCyprus

Listeria monocytogenes is among the most food-borne *** has the ability to grow over a range of temperature,including refrigeration *** kept in refrigerator more than the prescribed period of time create an opportunity for the occurrence of Listeria *** this review shows,the prevalence of *** has more likely evident in pasteurized milk than other dairy products,such as raw *** temperature and faults in technology during pasteurization can be the disposing factors for the presence of the organism in dairy *** organism,on the other hand,has been found to be resistant to those commonly known antibiotics that have human and veterinary importance,namely,ampicillin,Tetracycline,and chloramphenicol,streptomycin,erytromycin,penicillin G.,and *** ability of the organism can be mediated by different natural and acquired resistance mechanisms,such as self-transferrable plasmids,mobilizable plasmids,and conjugative *** emergence and spread of antibiotic resistance of *** has serious public health and economic impacts at *** paper has reviewed the prevalence and the antibiotic resistance of *** isolates of dairy products and the strategic mechanisms of the organism develop resistance against the antibiotics.

关键词： Listeria monocytogenes prevalence antibiotic resistance dairy products

Detection of Salmonella typhimurium in retail chicken meat and chicken giblets

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Biomedicine 2013年第9期3卷 678-681页

作者： Doaa M Abd El-Aziz Department of Food hygiene Faculty of Veterinary MedicineAssiut University

Objective:To detect Salmonella typhimurium(***),one of the most frequently isolated serovars from food borne outbreaks throughout the world,in retail raw chicken meat and ***:One hundred samples of retail raw chicken meat and giblets(Liver,heart and gizzard)which were collected from Assiut city markets for detection of the organism and by using Duplex PCR amplification of DNA using rfbj andfliC ***:*** was detected at rate of 44%,40%and 48%in chicken meat,liver and heart,respectively,but not detected in ***:The results showed high incidence of *** in the examined samples and greater emphasis should be applied on prevention and control of contamination during processing for reducing food-borne risks to consumers.

关键词： Salmonella typhimurium Chicken meat Duplex PCR

Seroprevalence of Cryptosporidium and risks of cryptosporidiosis in residents of Sothern Egypt: A cross-sectional study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Medicine 2019年第5期12卷 232-238页

作者： Ismail Elshahawy Fatma AbouElenien Department of Parasitology,Faculty of veterinary Medicine,South Valley University Department of hygiene and Preventive Medicine,Kafrelsheikh University Department of Parasitology Faculty of Veterinary Medicine South Valley University Department of hygiene and Preventive Medicine Kafrelsheikh University

Objective: To identify the serological epidemiology of Cryptosporidium infections and to follow up on the changes in the infection profile in Southern Egypt in order to establish a suitable scheme for control and prevention of ***: A total of 1 912(960 from human and 952 from animals) stool specimens and sera were screened for Cryptosporidium species using modified Ziehl Neelsen technique and a newly-developed enzyme-linked immunosorbent assay(ELISA).Environmental risk factors and socioeconomic data were surveyed by questionnaire between September 2016 and December ***: Totally, 20.83% of the human subjects were positive for Cryptosporidium infection tested by *** seropositivity was positively correlated with *** prevalence of Cryptosporidium infections in females was significantly higher than in males(P<0.05).The sensitivity and specificity of ELISA for Cryptosporidium were 99.06% and 88.88%, ***, a high prevalence of Cryptosporidium in domestic animals(42.20%).Conclusions: The study observed that Cryptosporidium infections are common in the study area, with water sanitation, socioeconomic level; eating habits and hygienic status are considered the main risk factors for ***, environmental sanitation and health education will be useful in reducing the prevalence of infection.

关键词： Cryptosporidium Epidemiology ELISA test Risk factors Serum Egypt

Acute phase reactants, challenge in the near future of animal production and veterinary medicine

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2005年第10期6卷 941-947页

作者： GRUYS E. ,TOUSSAINT M.J.M. ,UPRAGARIN N. ,VAN EDEREN A.M. ,ADEWUYI A.A. ,CANDIANI D. ,NGUYEN T.K.A. ,SABECKIENE (BALCIUTE) J. Department of Pathobiology Faculty of veterinary Medicine Utrecht University Utrecht the Netherlands Department of Pathobiology Faculty of veterinary Medicine Utrecht University Utrecht the Netherlands Department of Pathobiology Faculty of veterinary Medicine Utrecht University Utrecht the Netherlands Department of Pathobiology Faculty of veterinary Medicine Utrecht University Utrecht the Netherlands Department of Pathobiology Faculty of veterinary Medicine Utrecht University Utrecht the Netherlands Department of Pathobiology Faculty of veterinary Medicine Utrecht University Utrecht the Netherlands Department of Pathobiology Faculty of veterinary Medicine Utrecht University Utrecht the Netherlands Department of Pathobiology Faculty of veterinary Medicine Utrecht University Utrecht the Netherlands Department of Farm Resources and Production Medicine Faculty of veterinary Medicine Kasetsart University Nakhon Pathom Thailand Department of veterinary Morphophysiology University of Torino Italy Department of Embryo Transfer and Reproduction the National Institute of Animal Husbandry Hanoi Vietnam Department of Infectious Diseases Lithuanian veterinary Academy Kaunas Lithuania)

The future of acute phase proteins (APPs) in science is discussed in this paper. Many functions and associated pathological processes of APPs are unknown. Extrahepatic formation in local tissues needs attention. Local serum amyloid A (SAA) formation may be involved in deposition of AA-amyloid induced by conformational change of SAA resulting in amyloid formation, having tremendous food safety implications. Amyloidogenesis is enhanced in mouse fed beta pleated sheet-rich pro- teins. The local amyloid in joints of chicken and mammary corpora amylacea is discussed. Differences in glycosylation of glycoproteins among the APPs, as has been shown for α1-acid glycoprotein, have to be considered. More knowledge on the reactivity patterns may lead to implication of APPs in the diagnostics and staging of a disease. Calculation of an index from values of several acute phase variables increases the power of APPs in monitoring unhealthy individuals in animal populations. Vaccinations, just as infections in eliciting acute phase response seem to limit the profitability of vaccines because acute phase reactions are contraproductive in view of muscle anabolism. Interest is focused on amino acid patterns and vitamins in view of dietary nutrition effect on sick and convalescing animals. When inexpensive methodology such as liquid phase methods (nephelometry, turbidimetry) or protein array technology for rapid APPs measurement is available, APPs have a future in routine diagnostics. Specific groups of patients may be screened or populations monitored by using APPs.

关键词： Acute phase protein Amino acid Joint Mammary gland Mastitis Serum amyloid A (SAA) Vitamin A