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High order aberration and straylight evaluation after cataract surgery with implantation of an aspheric,aberration correcting monofocal intraocular lens

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International Journal of Ophthalmology(English edition) 2015年第4期8卷 736-741页

作者： Florian T A Kretz Tamer Tandogan Ramin Khoramnia Gerd U Auffarth International vision Correction Research Centre & David J Apple International Laboratory for Ocular Pathology of the Department of Ophthalmology University Hospital Heidelberg International vision Correction Research Network (***) Augenklinik Ahaus-Raesfeld-Rheine Gerl Group

·AIM: To evaluate the quality of vision in respect to high order aberrations and straylight perception after implantation of an aspheric, aberration correcting,monofocal intraocular lens(IOL).·METHODS: Twenty-one patients(34 eyes) aged 50 to83 y underwent cataract surgery with implantation of an aspheric, aberration correcting IOL(Tecnis ZCB00,Abbott Medical Optics). Three months after surgery they were examined for uncorrected(UDVA) and corrected distance visual acuity(CDVA), contrast sensitivity(CS)under photopic and mesopic conditions with and without glare source, ocular high order aberrations(HOA, Zywave II) and retinal straylight(C-Quant).· RESULTS: Postoperatively, patients achieved a postoperative CDVA of 0.0 log MAR or better in 97.1% of eyes. Mean values of high order abberations were +0.02±0.27(primary coma components) and-0.04 ±0.16(spherical aberration term). Straylight values of the C-Quant were 1.35±0.44 log which is within normal range of age matched phakic patients. The CS measurements under mesopic and photopic conditions in combination with and without glare did not show any statistical significance in the patient group observed(P ≥0.28).· CONCLUSION: The implantation of an aspherical aberration correcting monofocal IOL after cataractsurgery resulted in very low residual higher order aberration(HOA) and normal straylight.

关键词： cataract aberrations intraocular lens

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Large-scale particle tracking velocimetry with multi-channel CCD cameras

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International Journal of Sediment Research 2013年第1期28卷 103-110页

作者： Dan-xun LI Qiang ZHONG Ming-zhong YU Xing-kui WANG State Key Laboratory of Hydroscience and Engineering Tsinghua University Beijing Reco vision Technology Co. LTD

This paper presents a large-scale particle tracking velocimetry(LSPTV) system for measuring surface velocity in vast unsteady *** system consists of a flexible number of one-computer-six- camera working units connected via local network or the *** zero-tilting cameras are used to increases the field of view with minimum perspective *** synchronization of video outputs of all cameras facilitates uninterrupted image acquisition within the *** and efficiency of the multi-channel LSPTV are enhanced by optimizing illumination,flow seeding, image acquisition and correction,tracer identification,particle matching,and *** capacity of the LSPTV was demonstrated in the measurement of physical model flows for the Three Gorges Project.

关键词： Particle tracking velocimetry(PTV) Camera Unsteady flow Velocity

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Photobiomodulation for the treatment of retinal diseases: a review

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International Journal of Ophthalmology(English edition) 2016年第1期9卷 145-152页

作者： Ivayla I.Geneva Department of Ophthalmology State University of New York Upstate Medical University Center for Vision Research

Photobiomodulation（PBM）,also known as low level laser therapy,has recently risen to the attention of the ophthalmology community as a promising new approach to treat a variety of retinal conditions including agerelated macular degeneration,retinopathy of prematurity,diabetic retinopathy,Leber’s hereditary optic neuropathy,amblyopia,methanol-induced retinal damage,and possibly *** review evaluates the existing research pertaining to PBM applications in the retina,with a focus on the mechanisms of action and clinical *** available literature until April 2015 was reviewed using Pub Med and the following keywords：＂photobiomodulation AND retina＂,＂low level light therapy AND retina＂,＂low level laser therapy AND retina＂,and＂FR/NIR therapy AND retina＂.In addition,the relevant references listed within the papers identified through Pub Med were *** literature supports the conclusion that the low-cost and noninvasive nature of PBM,coupled with the first promising clinical reports and the numerous preclinical-studies in animal models,make PBM well-poised to become an important player in the treatment of a wide range of retinal ***,large-scale clinical trials will be necessary to establish the PBM therapeutic ranges for the various retinal diseases,as well as to gain a deeper understanding of its mechanisms of action.

关键词： photobiomodulation low level lasertherapy age-related macular degeneration retinopathy ofprematurity far-red to near-infrared retinal degeneration amblyopia retinitis pigmentosa methanol toxicity

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Traffic System Reliability Comparison Between Digital Driving and Conventional Driving

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Journal of Beijing Institute of Technology 2009年第4期18卷 412-415页

作者：王武宏沈中杰刘皓姚丽亚池内克史 School of Mechanical Engineering Beijing Institute of Technology Computer vision Laboratory The University of Tokyo

Driver behavior modeling is becoming increasingly important in the study of traffic safety and devel- opment of cognitive vehicles. An algorithm for dealing with reliability for both digital driving and conventional driving has been developed in this paper. Problems of digital driving error classification, digital driving error probability quantification and digital driving reliability simulation have been addressed using a comparison re- search method. Simulation results show that driving reliability analysis discussed here is capable of identifying digital driving behavior characteristics and achieving safety assessment of intelligent transportation system.

关键词： driving behavior digital driving characteristics cognitive vehicle intelligent transportation system

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Evaluation of the iridocorneal angle with accommodation using optical coherence tomography

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International Journal of Ophthalmology(English edition) 2017年第10期10卷 1614-1616页

作者： Daniel Monsálvez-Romín Antonio Del águila-Carrasco Teresa Ferrer-Blasco José J.Esteve-Taboada Robert Montés-Micó Optics and Optometry and vision Sciences Department University of Valencia

The changes in the iridocorneal angle structure during accommodation are assessed by means of anterior segment optical coherence *** right eyes were included in the *** device used for the measurement was the Visante？omni *** stimuli were set up at different vergences（0.0 D,-1.5 D,and-3.0 D）.The angle opening distance 500 and 750,the trabecular iris space area 500 and 750,and the scleral spur angle parameters were assessed at the nasal and temporal *** results in the iridotrabecular angle comparing the three accommodative states of the eye did not yield any statistically significant difference at nasal or temporal angle *** light of our results and in the conditions of our study,the structures of the iridocorneal angle are not significantly changed with accommodation.

关键词： iridocorneal angle accommodation optical coherence tomography anterior segment

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The effect of stochastic acceleration and delay probability on the velocity and the gap between vehicles in traffic flow

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Chinese Physics B 2009年第8期18卷 3347-3354页

作者：盛鹏赵树龙王俊峰唐鹏高琳 School of Computer Science Sichuan University Key Laboratory of Fundamental Synthetic vision Graphics and Image Science for National Defense Sichuan University

This paper proposes a new combined cellular automaton （CA） model considering the driver behavior of stochastic acceleration and delay with the velocity of the preceding vehicle and the gap between the successive vehicles based on the WWH model and the noise-first NaSch model. It introduces the delay probability varying with the gap, adds the anticipation headway and increases the acceleration with a certain probability. Through these simulations, not only can the metastable state and start-stop wave be obtained but also the synchronized flow which the wide moving jam results in. Moreover, the effect of stochastic acceleration and delay on traffic flow is discussed by analyzing the correlation of traffic data. This indicates that synchronized flow easily emerges in the critical area between free flow and synchronized flow when acceleration and delay are synchronized or their probability is close to 0.5.

关键词： traffic flow noise-first NaSch model synchronized flow long-range correlation

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SRNET:A Shallow Skip Connection Based Convolutional Neural Network Design for Resolving Singularities

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Journal of Computer Science & Technology 2019年第4期34卷 924-938页

作者： Robail Yasrab Computer vision Laboratory School of Computer ScienceUniversity of NottinghamNottinghamNG8-1BBU.K.

Convolutional neural networks(CNNs)have shown tremendous progress and performance in recent *** emergence,CNNs have exhibited excellent performance in most of classification and segmentation ***,the CNN family includes various architectures that dominate major vision-based recognition ***,building a neural network(NN)by simply stacking convolution blocks inevitably limits its optimization ability and introduces overfitting and vanishing gradient *** of the key reasons for the aforementioned issues is network singularities,which have lately caused degenerating manifolds in the loss *** situation leads to a slow learning process and lower *** this scenario,the skip connections turned out to be an essential unit of the CNN design to mitigate network *** proposed idea of this research is to introduce skip connections in NN architecture to augment the information flow,mitigate singularities and improve *** research experimented with different levels of skip connections and proposed the placement strategy of these links for any *** prove the proposed hypothesis,we designed an experimental CNN architecture,named as Shallow Wide ResNet or SRNet,as it uses wide residual network as a base network *** have performed numerous experiments to assess the validity of the proposed ***-10 and CIFAR-100,two well-known datasets are used for training and testing *** final empirical results have shown a great many of promising outcomes in terms of performance,efficiency and reduction in network singularities issues.

关键词： convolutional neural network(CNN) wide residual network(WRN) dropout skip connection deep neural network(DNN)

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Meibomian gland dysfunction model induced with complete Freund’s adjuvant in C57BL/6 mice

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International Journal of Ophthalmology(English edition) 2020年第11期13卷 1705-1712页

作者： Yang Lu Yue Yin Lan Gong Department of Ophthalmology and vision Science Eye&ENT Hospital of Fudan UniversityShanghai 200031China

AIM:To establish a new inflammatory animal model of meibomian gland dysfunction(MGD)in C57BL/6 ***:C57BL/6 mice were randomly divided into complete Freund’s adjuvant(CFA)group(14 animals,14 eyes),naphthazolin hydrochloride(NH)group(14 animals,14 eyes)and control group(14 animals,14 eyes).In CFA group,CFA was used in eyelid conjunctiva injection;in NH group,NH eye drops were used twice a day;control group was injected with equal dose of saline at the same time point and same site with animals in CFA *** meibomian gland orifices score(MGOS)was evaluated on a scale of 0 to 3 in the middle five meibomian gland orifices of the upper and lower eyelid using slit *** the successful induction of each animal model,intense pulsed light(IPL)was introduced on each mouse in CFA and NH *** red O(ORO),hematoxylin and eosin(H&E)staining were performed before and after successful induction of CFA,NH and control ***:At 12wk after CFA injection,inflammatory cell infiltration and fiber necrosis was observed,with acinar density and duct dilatation significantly lower compared with control *** NH group,the meibomian gland acini were relatively smaller and deformed compared with control group,the number of meibomian gland acini was also slightly *** inflammatory cell or fiber necrosis was observed in NH *** three times of IPL treatment(5/10 mice in each group,and the other 5 mice served as non-IPL control),MGOS was significantly lower in IPL-treated mice in NH group(P<0.01).After three times of IPL treatment,the MGOS of NH group was significantly lower than that in the CFA group(P<0.01).CONCLUSION:We develop a novel animal model that studies the role of inflammation in the development of MGD and IPL *** model indicates that persistent inflammatory state may be the cause of MGD and weaken the therapeutic effect of IPL.

关键词： meibomian gland dysfunction complete Freund's adjuvant inflammation acinar atrophy intense pulsed light

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View on microRNAs as a potential tool to fight blindness: focus on Müller glia and gliosis

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Neural Regeneration Research 2022年第7期17卷 1501-1502页

作者： Stefanie Gabriele Wohl The State University of New York College of OptometryDepartment of Biological and Vision SciencesNew YorkNYUSA

The neural retina is a part of the central nervous *** it lacks regenerative capacity,in an event of injury or disease,neuronal loss leads to visual impairment and often to ***,Müller glia(MG),the predominant glia in the retina,undergo a variety of molecular and cellular changes and discontinue to carry out their important regular functions in the tissue(e.g.,maintaining tissue homeostasis and nurturing neurons).

关键词： homeostasis predominant carry

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An adaptive spatial clustering method for automatic brain MR image segmentation

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Progress in Natural Science:Materials International 2009年第10期19卷 1373-1382页

作者： Jingdan Zhang,Daoqing Dai Center for Computer vision and Department of Mathematics,Sun Yat-Sen(Zhongshan) University,Guangzhou 510275,China [a]Center for Computer vision and Department of Mathematics Sun Yat-Sen (Zhongshan) University Guangzhou 510275 China

In this paper,an adaptive spatial clustering method is presented for automatic brain MR image segmentation,which is based on a competitive learning algorithm-self-organizing map(SOM).We use a pattern recognition approach in terms of feature generation and classifier ***,a multi-dimensional feature vector is constructed using local spatial ***,an adaptive spatial growing hierarchical SOM(ASGHSOM) is proposed as the classifier,which is an extension of SOM,fusing multi-scale segmentation with the competitive learning clustering algorithm to overcome the problem of overlapping grey-scale intensities on boundary ***,an adaptive spatial distance is integrated with ASGHSOM,in which local spatial information is considered in the clustering process to reduce the noise effiect and the classification *** proposed method is validated by extensive experiments using both simulated and real MR data with varying noise level,and is compared with the state-of-the-art algorithms.

关键词： Self-organizing map Growing hierarchical SOM Adaptive spatial distance Image segmentation MR images

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