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Long-term monitoring of cycles in Clethrionomys rutilus in the Yukon boreal forest

Integrative Zoology 2024年第1期19卷 27-36页

作者： Charles J.KREBS Alice J.KENNEY B.Scott GILBERT Rudy BOONSTRA department of Zoology University of British ColumbiaVancouverBritish ColumbiaCanada Renewable Resources Management Program Yukon UniversityWhitehorseYukonCanada department of Biological sciences University of Toronto ScarboroughTorontoOntarioCanada

Baseline studies of small rodent populations in undisturbed ecosystems are *** report here 50 years of mon-itoring and experimentation in Yukon of a dominant rodent species in the North American boreal forest,the red-backed vole Clethrionomys *** voles breed in summer,weigh 20–25 g,and reach a maximum density of 20 to 25 per *** populations have shown consistent 3–4-year cycles for the last 50 years with the only change being that peak densities averaged 8/ha until 2000 and 18/ha since that *** the last 25 years,we have measured food resources,predator numbers,and winter weather,and for 1-year social interactions,to estimate their contribution to changes in the rate of summer increase and the rate of overwinter *** these potential limiting factors could contribute to changes in density,and we measured their relative contributions statistically with multiple *** rate of winter decline in density was related to both food supply and winter *** rate of summer increase was related to summer berry crops and white spruce cone *** measure of predator numbers was related to winter or summer changes in vole *** was a large signal of climate change effects in these *** is no density dependence in summer population growth and only a weak one in winter population *** of our results provide a clear understanding of what generates 3–4-year cycles in these voles,and the major missing piece may be an understanding of social interactions at high density.

关键词： boreal forest climate change density dependence population cycles predation winter severity

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Investigating low dispersion isotope dissolution Lu-Hf garnet dates via in situ Lu-Hf geochronology,Kanchenjunga Himal

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Geoscience Frontiers 2024年第3期15卷 137-145页

作者： Kyle P.Larson John M.Cottle Mark Button Brendan Dyck Iva Lihter Sudip Shrestha department of Earth Environmental and Geographic SciencesUniversity of British ColumbiaOkanaganKelownaCanada department of Earth Science University of CaliforniaSanta BarbaraUSA Fipke Laboratory for Trace Element Research University of British ColumbiaOkanaganKelownaCanada

Re-examination of three specimens from the Kanchenjunga Himal of Nepal via in situ Lu-Hf garnet geochronology yields evidence of multiple garnet growth *** analyses from grain cores in two specimens define Paleozoic regressions whereas analyses from grain rims in the same specimens define low-precision regressions consistent with the timing of Himalayan *** dates contrast with previously published low dispersion,ca.290 Ma isotope dissolution(ID)Lu-Hf garnet dates for the same *** of Lu and spot age distribution in representative grains from the specimens examined yields calculated dates that approximate the Permian-age regressions through the original ID *** findings demonstrate that it is possible to generate low dispersion ID Lu-Hf data from multigenerational garnet with significantly different-age growth events when approximately equal proportions of the different age reservoirs are included in multi-component aliquots.

关键词： Lu-Hf geochronology In situ Lu-Hf geochronology Kanchenjunga Himal

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Evolution of biomass particles during pelletization process

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Particuology 2024年第3期86卷 182-187页

作者： Hamid Rezaei Maryam Tajilrou Jun Sian Lee Kanages Singaraveloo Anthony Lau Shahab Sokhansanj Biomass and Bioenergy Research Group Department of Chemical and Biological EngineeringUniversity of British ColumbiaVancouverCanada

Pulverizing is an essential unit operation in co-firing biomass with *** are only compatible with pellet forms of fibrous biomass materials and crush them down to their original forming particle *** is why the data on the size distribution of the particles forming a biomass pellet is crucial to achieving optimum combustion *** current study determines the internal particle size distribution of pellets after wet disintegration,following Iso 17830 standard,and aims to suggest improvements to the mentioned standard based on new measured *** were carried out on white wood pellets(no bark)and brown wood pellets containing bark at four water temperatures:20,40,60,and 95℃,with or without *** particle size distribution of the pre-pelletizer wood particles was also measured and compared with particles in the formed *** water temperature of 20℃ was found to be adequate for the complete disintegration of pellets,and no mechanical stirring was *** 30% of particles in the disintegrated pellets were 0.5-1.0 *** changes the particle size distribution to smaller *** disintegrated bark pellets contained more fines than white pellets.

关键词： Wood pellets Particle sizes distribution Wet disintegration Stirring Water temperature

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Monogenic features of urolithiasis: A comprehensive review

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Asian Journal of Urology 2024年第2期11卷 169-179页

作者： Kyo Chul Koo Abdulghafour Halawani Victor K.F.Wong Dirk Lange Ben H.Chew department of Urology Yonsei University College of MedicineSeoulRepublic of Korea department of Urology King Abdulaziz UniversityJeddahSaudi Arabia department of urological sciences University of British ColumbiaStone Centre at Vancouver General HospitalVancouverBritish ColumbiaCanada

Objective: Urolithiasis formation has been attributed to environmental and dietary factors. However, evidence is accumulating that genetic background can contribute to urolithiasis formation. Advancements in the identification of monogenic causes using high-throughput sequencing technologies have shown that urolithiasis has a strong heritable ***: This review describes monogenic factors implicated in a genetic predisposition to urolithiasis. Peer-reviewed journals were evaluated by a PubMed search until July 2023 to summarize disorders associated with monogenic traits, and discuss clinical implications of identification of patients genetically susceptible to urolithiasis ***: Given that more than 80% of urolithiases cases are associated with calcium accumulation, studies have focused mainly on monogenetic contributors to hypercalciuric urolithiases, leading to the identification of receptors, channels, and transporters involved in the regulation of calcium renal tubular reabsorption. Nevertheless, available candidate genes and linkage methods have a low resolution for evaluation of the effects of genetic components versus those of environmental, dietary, and hormonal factors, and genotypes remain undetermined in the majority of urolithiasis ***: The pathophysiology underlying urolithiasis formation is complex and multifactorial, but evidence strongly suggests the existence of numerous monogenic causes of urolithiasis in humans.

关键词： Gene Genetic expression Inheritance pattern Urolithiasis

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Rapid growth in a large Cambrian apex predator

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National Science Review 2024年第3期11卷 128-136页

作者：吴雨 Stephen Pates Daniel Pauly 张兴亮傅东静 State Key Laboratory of Continental Dynamics and Shaanxi Key Laboratory of Early Life and Environment Department of Geology Northwest University department of Zoology University of Cambridge Institute for the Oceans and Fisheries University of British Columbia Nanjing Institute of Geology and Palaeontology Chinese Academy of Sciences

Despite the importance of ontogenetic data on early diverging euarthropods to our understanding of the ecology and evolution of past life, the data are distinctly lacking, as reconstructing life histories of fossil animals is often challenging. Here we report the growth trajectory of frontal appendages of the apex predator Amplectobelua symbrachiata, one of the most common radiodont arthropods from the early Cambrian Chengjiang biota(c. 520 Ma) of China. Analysis of 432 specimens(9.1–137.1 mm length; 1.3–25.6 mm height) reveals that appendages grew isometrically, with an estimated maximum size of the whole animal of c. 90 cm. Individuals grew rapidly compared to extant arthropods, as assessed using the electronic length-frequency analysis(ELEFAN) approach. Therefore, we show that the Cambrian apex predator A. symbrachiata was an extremely fast-growing arthropod, with an unusual life history strategy that formed as part of the escalatory ‘arms race’ that shaped the Cambrian explosion over 500 Ma.

关键词： stem-group Euarthropoda Radiodonta post-embryonic development growth dynamics Cambrian Explosion

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HDPairFinder:A data processing platform for hydrogen/deuterium isotopic labeling-based nontargeted analysis of trace-level amino-containing chemicals in environmental water

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Journal of Environmental sciences 2024年第2期136卷 583-593页

作者： Tingting Zhao Kristin Carroll Caley B.Craven Nicholas J.P.Wawryk Shipei Xing Jian Guo Xing-Fang Li Tao Huan department of Chemistry Faculty of ScienceUniversity of British ColumbiaVancouver Campus2036 Main MallVancouverBritish ColumbiaV6T 1Z1Canada Division of Analytical and Environmental Toxicology Department of Laboratory Medicine and PathologyFaculty of Medicine and DentistryUniversity of AlbertaEdmontonAlberta T6G 2G3Canada

The combination of hydrogen/deuterium(H/D)formaldehyde-based isotopic methyl labeling with solid-phase extraction and high-performance liquid chromatography–high resolution mass spectrometry(HPLC-HRMS)is a powerful analytical solution for nontargeted analysis of trace-level amino-containing chemicals in water *** the huge amount of chemical information generated in HPLC-HRMS analysis,identifying all possible H/Dlabeled amino chemicals presents a significant challenge in data *** address this,we designed a streamlined data processing pipeline that can automatically extract H/D-labeled amino chemicals from the raw HPLC-HRMS data with high accuracy and ***,we developed a cross-correlation algorithm to correct the retention time shift resulting from deuterium isotopic effects,which enables reliable pairing of H-and D-labeled ***,we implemented several bioinformatic solutions to remove false chemical features generated by in-source fragmentation,salt adduction,and natural13C ***,we used a data mining strategy to construct the AMINES library that consists of over 38,000 structure-disjointed primary and secondary amines to facilitate putative compound ***,we integrated these modules into a freely available R program,*** rationale of each module was justified and its performance tested using experimental H/D-labeled chemical standards and authentic water *** further demonstrated the application of HDPairFinder to effectively extract N-containing contaminants,thus enabling the monitoring of changes of primary and secondary N-compounds in authentic water *** is a reliable bioinformatic tool for rapid processing of H/D isotopic methyl labeling-based nontargeted analysis of water samples,and will facilitate a better understanding of N-containing chemical compounds in water.

关键词： Isotope labeling Nontargeted analysis Reactive N-compounds HPLC-HRMS Source water

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Giant panda(Ailuropoda melanoleuca)neonates use broadband calls to communicate with their mothers

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Integrative Zoology 2024年第2期19卷 277-287页

作者： Lin ZHAO Jianbin CHENG Wen ZENG Bo YANG Guiquan ZHANG Desheng LI Hemin ZHANG Christina DBUESCHING Dingzhen LIU Ministry of Education Key Laboratory of Biodiversity Science and Ecological EngineeringCollege of Life SciencesBeijing Normal UniversityBeijingChina Key Laboratory of State Forestry and Grassland Administration on Conservation Biology of Rare Animals in The Giant Panda National Park China Conservation and Research Center for the Giant PandaDujiangyanSichuan611830China department of Biology Irving K.Barber Faculty of ScienceUniversity of British ColumbiaOkanaganKelownaBritish ColumbiaCanada

Infant call structure should have evolved to elicit maximum maternal attention and *** of giant pandas produce three types of vocalizations reported to be vitally important in the context of mother–infant ***,how cubs,0–15 days old,communicate with their mothers to elicit maternal care remains *** analyzed 12 different call parameters of 3475 squawks,1355 squalls,and 491 croaks from 11 captive giant panda(Ailuropoda melanoleuca)neonates from age 0 to 15 *** playback experiments,we also tested whether mothers could detect *** results show that neonates use broadband calls with ultrasonic frequencies up to 65 kHz to convey information about their physiological needs and to attract maternal *** playback experiments,we tested if mothers reacted differently to broadband calls(BBC)than to artificially altered calls that included only frequencies20 kHz(USC).Playback confirmed that,although adult females responded significantly less often to USC,BBC than to or AUDC,they could detect USC,BBC and generally made appropriate behavioral responses,indicating a potential benefit for neonates to utilize ultrasonic and broadband *** findings provide a new insight into mother–infant communication in giant pandas and will be helpful for reducing the mortality of cubs,younger than 1 month old,in captivity.

关键词： acoustic communication broadband calls maternal care neonates ultrasonic frequencies

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Is there hybridization between 2 species of the same genus in sympatry?——The genetic relationships between Anoplophora glabripennis,Anoplophora chinensis,and putative hybrids

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Insect Science 2024年第2期31卷 633-645页

作者： Haiwen Qin Huachao Xu Arnaud Capron Ilga Porth Mingming Cui Melody A.Keena Xiaofang Deng Juan Shi Richard C.Hamelin Sino-French Joint Laboratory for Invasive Forest Pests in Eurasia Department of ForestBejing Forestry UniversityBejingChina department of Forest and Conservation sciences The University of British ColumbiaVancouverCanada College of Forestry and Biotechnology Zhejiang A&F UniversityHangzhouChina department of Wood and Forest sciences Laval UniversityQuebecCanada 5 Department of AgricultureNorthern Research StationUSDA Forest ServiceHamdenConnecticutUSA Changchun Landscape Plant Conservation Station Bureau of Forestry and Landscaping of ChangchunChangchunChina

Anoplophora glabripennis(Asian longhorn beetle,ALB)and Anoplophora chinensis(Citrus longhorn beetle,CLB)are native forest pests in China;they have become important international quarantine *** are found using the same Salix aureopendula host tree of Cixi,Zhejiang province,*** this host tree,we collected additional beetles that appeared to be morphologically intermediate between ALB and *** using a stereoscope,we observed that there were several bumps on the base of the elytra,which was inconsistent with ALB,which typically has a smooth elytral base,but was more like CLB,which has numerous short tubercles on the elytral *** their sympatry and intermediate morphology,we hypothesized that these may represent ALB×CLB *** studied the genomic profiles for 46 samples(ALB,CLB,and putative hybrids)using genotyping-by-sequencing(GBS)providing a reduced representation of the entire *** principal component analyses on the 163 GBS-derived single nucleotide polymorphism data,we found putative hybrids tightly clustered with ALB,but genetically distinct from the CLB ***,our initial hybrid hypothesis was not supported by genomic ***,while mating experiments between adult ALB and CLB were successful in 4 separate years(2017,2018,2020,and 2021),and oviposition behavior was observed,no progeny was *** employed population genomic analysis and biological hybridization experiments,we conclude that the putative hybrids represent newly discovered morphological variants within *** approach further confirmed the advantage of genome-wide information for Anoplophora species assignment in certain ambiguous classification cases.

关键词： Anoplophora chinensis Anoplophora glabripenni sg enotyping-bysequencing invasive pest mating putative hybrid

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Role of practice standardization in outcome optimization for CDH

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World Journal of Pediatric Surgery 2024年第2期7卷 110-118页

作者： Alexandra Dimmer Robert Baird Pramod Puligandla Harvey E.Beardmore Division of Pediatric Surgery Department of Pediatric SurgeryMontreal Children's HospitalMontrealQuebecCanada Division of Pediatric General and Thoracic Surgery British Columbia Children's HospitalVancouverBritish ColumbiaCanada Harvey E.Beardmore department of Pediatric Surgery McGill UniversityMontrealQuebecCanada

Standardization of care seeks to improve patient outcomes and healthcare delivery by reducing unwanted variations in care as well as promoting the efficient and effective use of healthcare *** are many types of standardization,with clinical practice guidelines(CPGs),based on a stringent assessment of evidence and expert consensus,being the hallmark of high-quality *** article outlines the history of CPGs,their benefits and shortcomings,with a specific focus on standardization efforts as it relates to congenital diaphragmatic hernia management.

关键词： congenital clinical shortcomings

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A machine learning-guided design and manufacturing of wearable nanofibrous acoustic energy harvesters

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Nano Research 2024年第10期17卷 9181-9192页

作者： Negar Hosseinzadeh Kouchehbaghi Maryam Yousefzadeh Aliakbar Gharehaghaji Safoora Khosravi Danial Khorsandi Reihaneh Haghniaz Ke Cao Mehmet R.Dokmeci Mohammad Rostami Ali Khademhosseini Yangzhi Zhu Terasaki Institute for Biomedical Innovation Los AngelesCA 91367USA department of Textile Engineering Amirkabir University of Technology(Tehran Polytechnic)Hafez Avenue*** TehranIran department of Electrical and Computer Engineering University of British ColumbiaVancouverBC V6T1Z4Canada Chemical sciences Division Oak Ridge National LaboratoryOak RidgeTN 37831USA department of Computer Science University of Southern CaliforniaLos AngelesCA 90007USA

Nanofibrous acoustic energy harvesters(NAEHs)have emerged as promising wearable platforms for efficient noise-to-electricity conversion in distributed power energy systems and wearable sound amplifiers for assistive listening ***,their reallife efficacy is hampered by low power output,particularly in the low-frequency range(<1 kHz).This study introduces a novel approach to enhance the performance of NAEHs by applying machine learning(ML)techniques to guide the synthesis of electrospun polyvinylidene fluoride(PVDF)/polyurethane(PU)nanofibers,optimizing their application in wearable *** use a feed-forward neural network along with solving an optimization problem to find the optimal input values of the electrospinning(applied voltage,nozzle-collector distance,electrospinning time,and drum rotation speed)to generate maximum output performance(acoustic-to-electricity conversion efficiency).We first prepared a dataset to train the network to predict the output power given the input variables with high *** introducing the neural network,we fix the network and then solve an optimization problem using a genetic algorithm to search for the input values that lead to the maximum energy harvesting *** ML-guided wearable PVDF/PU NAEH platform can deliver a maximal acoustoelectric power density output of 829μW/cm^(3) within the surrounding noise *** addition,our system can function stably in a broad frequency(0.1-2 kHz)with a high energy conversion efficiency of 66%.Sound recognition analysis reveals a robust correlation exceeding 0.85 among lexically akin terms with varying sound intensities,contrasting with a diminished correlation below 0.27 for words with disparate semantic ***,this work provides a previously unexplored route to utilize ML in advancing wearable NAEHs with excellent practicability.

关键词： wearable electronics acoustic energy harvester machine learning piezoelectric nanogenerator electrospun nanofiber

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