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SCATTERING OF SOUND FROM A PAIR OF FINITE CYLINDERS——A PRELIMINARY STUDY APPLICABLE TO SOUND INTENSITY TECHNIQUE

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Chinese Journal of Acoustics 1989年第3期8卷 261-271页

作者： Lin Mingliang univ of kentucky United States

In this paper, it is studied that the scattering effect is caused by microphones itself, on both wave magnitude and phase. The experimental method was found difficult to do this. We will apply the Boundary Element Method(BEM) to the problem and explain the results obtained. The numerical method seems to be a powerful tool in this situation.

关键词： SCATTERING OF SOUND FROM A PAIR OF FINITE CYLINDERS A PRELIMINARY STUDY APPLICABLE TO SOUND INTENSITY TECHNIQUE

Keyhole Double-Sided Arc Welding Process

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Journal of Materials Science & Technology 2001年第1期17卷 159-160页

作者： Yuming ZHANG Shaobin ZHANG and bang JIANG Welding Research Laboratory, Center for Robottes and Manufacturing Systems, university of kentucky, Lexington, kentucky 40506, USA. Lin WU National Key Laboratory for Advanced Welding Production Technology, Harbi Cent. for Robotics Univ. of Kentucky Lexington KY 40506 United States

In the proposed method, the current/arc is guided through the keyhole so that the energy of the plasma jet is compensated while it is consumed in heating the workpiece along the keyhole. As a result, deep narrow penet... 详细信息

关键词： Arc Keyhole Double-Sided Arc Welding Process Zhang

Plasma-Jet Forming of Sheet Metal Shapes

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Journal of Materials Science & Technology 2001年第1期17卷 115-116页

作者： A.T.Male Y.W.Chen P.J.Li C.Pan and Y.M.Zhang Center for Robottes and Manufacturing Systems, university of kentucky, Lexington, KY 40506-0108, USA Cent. for Robotics. and Manuf. Sys. Univ. of Kentucky Lexington Ky 40506-0108 United States

Plasma-jet forming is a newly proposed flexible sheet metal forming process. A non-transferred arc plasma torch is used as a controllable heat source to produce internal stress in sheet metals, causing plastic deformation without the necessity of hard tooling. This method has potential for rapid prototyping of sheet metal parts by reducing development costs and lead times. A robotic system has been used to perform simple linear bends in several different alloys. In order to develop a controllable process and to improve the forming accuracy, the effects of various process parameters on the obtained shape changes and on the resulting structure and properties have been studied. The overall goal is to understand the roles of the forming parameters and their inter-relationship in optimizing the forming procedure-a high forming speed without damage to the material structure or properties.

关键词： CIRP Plasma-Jet Forming of Sheet Metal Shapes Chen

Security and Privacy in the Computer Forensics Context

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Security and Privacy in the Computer Forensics Context

Serum M2-pyruvate kinase: A promising non-invasive biomarker for colorectal cancer mass screening

2006 10th International Conference on Communication Technology（ICCT 2006）

作者： S.Srinivasan Professor of Computer Information Systems Director Center for Information Assurance University of Louisville Louisville Kentucky 40292 USA

ISBN: (纸本)1424408016;9781424408016

Today computers are used in numerous day-to-day activities as a communications tool. In this regard several different applications are used to generate and store important documents. These documents contain vital data to the user and at times to an investigator in the event a crime is committed using that computer. The user would expect reasonable security precautions to be in place to protect the data on the computer, especially when the computer is connected to the Internet. The user with deceptive goals in mind would want to hide information where as a Computer Forensics investigator would want to find out the hidden information for evidence. In this paper we examine several security features that are commonly used and how such precautions are thwarted by Computer Forensics tools and their impact on privacy.

关键词： Computer security Privacy Forensics Data security Information security Context Application software Computer crime Protection Internet

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World Journal of Gastrointestinal Oncology 2012年第6期4卷 145-151页

作者： Wen Meng Hong-Hong Zhu Ze-Feng Xu Shan-Rong Cai Qi Dong Qiang-Rong Pan Shu Zheng Su-Zhan Zhang Zhejiang univ Canc Inst Key Lab Canc Prevent & Intervent China Natl Minist EducKey Lab Mol Biol Med Sci Hangzhou 310009 Zhejiang Peoples R China Zhejiang univ Affiliated Hosp 2 Sch Med Hangzhou 310009 Zhejiang Peoples R China Hangzhou First Peoples Hosp Dept Cardiothorac Surg Hangzhou 310006 Zhejiang Peoples R China Capella univ Sch Publ Serv Leadership Dept Hlth Adm Publ Hlth & Gerontol Minneapolis MN 55403 USA St Louis univ Sch Publ Hlth Dept Community Hlth St Louis MO 63104 USA Western kentucky univ Coll Hlth & Human Serv Dept Publ Hlth Bowling Green KY 42101 USA

AIM: To explore the value of serum M2-pyruvate kinase (M2-PK) in colorectal cancer (CRC) mass screening. METHODS: We conducted a molecular epidemiology study in Hangzhou, China, from year 2006 to year 2008. Serum samples were collected from 93 CRC, 41 advanced adenomas, 137 adenomas, 47 non-adenomatous polyps, and 158 normal participants in a community setting. Serum M2-PK and carcinoembryonic antigen (CEA) were measured using Enzyme-linked immunosorbent assay. SPSS 16.0 software was used to perform data analysis. Area under the receiver operating characteristic curve (AUC), sensitivity, and specificities were estimated for serum M2-PK in diagnosis of colorectal lesions and compared with CEA. RESULTS: Average serum M2-PK value among 158 normal people was 2.96 U/mL and not affected by gender (P = 0.47) or age (P = 0.59). Average serum M2-PK (U/mL) was 14.75 among stage III and 13.10 among stage?I?and II CRC patients, about 4 times higher than that among normal people. Average serum M2-PK was 8.58, 6.70, 5.13 and 2.51 U/mL among advanced adenoma, adenomas, non-adenomatous polyps, and inflammatory bowel disease patients, respectively. AUC for serum M2-PK was greater than that for CEA among all colorectal lesions. AUC for serum M2-PK was 0.89 (0.84, 0.94) (95% confidence interval), higher than that for CEA [0.70 (0.62-0.79)] in CRC stage?I?and II, 0.89 (0.84-0.94) vs 0.73 (0.63-0.83) in CRC stage III, 0.81 (0.74-0.86) vs 0.63 (0.53 - 0.73) in advanced adenomas, 0.69 (0.64-0.76) vs 0.54 (0.47-0.60) in adenomas, and 0.69 (0.62-0.78) vs 0.58 (0.48-0.68) in non-adenomatous polyps. The diagnostic sensitivity for all colorectal lesions increased with decrease in the cut-off value of serum M2-PK. The diagnostic sensitivity (%) of serum M2-PK was 100.00 for CRC, 95.12 advanced adenoma, 82.48 adenoma, and 82.98 non-adenomatous polyp. There were no CRC cases missed and 40.51% of unnecessary colonoscopies were avoided when the cut-off value was 2.00 U/mL. CONCLUSION: Serum M2-PK c

关键词： Serum M2-pyruvate kinase Colorectal cancer screening Serum biomarker Carcinoembryonic antigen

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老年F344大鼠黑质中铁沉积的研究

神经解剖学杂志 2003年第3期19卷 283-288页

作者：张进禄蔡青徐群渊 Y.Ai G.Bing Z.Zhang D.M.Gash 首都医科大学北京神经科学研究所北京100054 Department of Anatomy and Neurobiology Univ.of KentuckyCollege of Medicinelexingtonky40536

脑内一些区域的胶质细胞中铁过多沉积和由铁介导的“氧化应激反应”可能与 Parkinson病 (PD)等神经退行性疾病的发病有关。但目前对老年 F 3 44大鼠中脑黑质铁沉积的亚细胞结构研究报道还不多。本研究选用老年 (2 4个月 ) Fischer (F3 ... 详细信息

脑内一些区域的胶质细胞中铁过多沉积和由铁介导的“氧化应激反应”可能与 Parkinson病 (PD)等神经退行性疾病的发病有关。但目前对老年 F 3 44大鼠中脑黑质铁沉积的亚细胞结构研究报道还不多。本研究选用老年 (2 4个月 ) Fischer (F3 44)大鼠 ,采用免疫组织化学、激光共聚焦显微镜、透射电子显微镜及电子探针元素能量微分析等技术 ,对中脑黑质部位铁的沉积进行了形态学观察。结果显示 :在光镜下 ,作为铁的主要储存形式 -铁结合蛋白在黑质网状部有明显增加并伴有小胶质细胞的增加 ;激光共聚焦显微镜观察到它们很少存在于多巴胺神经元及星形胶质细胞而主要存在于小胶质细胞中 ;利用电子探针检测显示游离铁元素主要存在于星形胶质细胞的胞浆内 ,也在小胶质细胞、少突胶质细胞及部分神经元的胞浆内发现有铁元素沉积。本文作者认为 :随年龄的增长 ,黑质中小胶质细胞增加可能是铁在黑质中沉积的原因之一 ,后者引起的自由基化增加所导致的老年神经系统的氧化损伤 ,可能是导致

关键词：铁氧化应激电子微探针黑质老年大鼠神经元

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Interview of Robert ***

Science China Chemistry 2011年第12期54卷 2018-2020页

作者： Xue, Ziling Grubbs, Robert H. univ Tennessee Knoxville TN 37996 USA CALTECH Pasadena CA 91125 USA Stanford univ Stanford CA 94305 USA

Robert H. Grubbs is a Nobel Laureate and the Victor and Eliza-beth Atkins Professor of Chemistry at the California Institute of Technology, USA. He grew up in the State of kentucky,

关键词：诺贝尔奖获得者采访加州理工学院肯塔基州

A novel long non-coding RNA Myolinc regulates myogenesis through TDP-43 and Filip1

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Journal of Molecular Cell Biology 2018年第2期10卷 102-117页

作者： Giuseppe Militello Mohammed Rabiul Hosen Yuliya Ponomareva Pascal Gellerts Tyler Weirick David John Sajedah Mahmoud Hindi Kamel Mamchaoui Vincent Mouly Claudia Doring Lidan Zhang Miki Nakamura Ashok Kumar So-ichiro Fukada Stefanie Dimmeler Shizuka Uchida Institute of Cardiovascular Regeneration Centre for Molecular Medicine Goethe University Frankfurt Frankfurt am Main 60590 Germany German Center for Cardiovascular Research Partner side Rhein-Main Frankfurt am Main 60590 Germany Department of Biosciences Goethe University Frankfurt Frankfurt am Main 60438 Germany Cardiovascular Innovation Institute University of Louisville Louisville KY 40202 USA Breast Cancer Now Toby Robins Research Centre Institute of Cancer Research London SW3 6JB UK Department of Anatomical Sciences and Neurobiology University of Louisville School of Medicine Louisville KY 40202 USA Sorbonne universites UPMC Univ Paris 06 INSERM UMRS974 CNRS FRE3617 Center for Research in Myology Paris 75013 France Dr. Senckenberg Institute of Pathology Goethe University Frankfurt Frankfurt am Main 60590 Germany Laboratory of Molecular and Cellular Physiology Graduate School of Pharmaceutical Sciences Osaka University Osaka 565-0871 Japan

Myogenesis is a complex process required for skeletal muscle formation during embryonic development and for regeneration and growth of myofibers in adults. Accumulating evidence suggests that long non-coding RNAs （IncRNAs） play key roles in regulating cell fate decision and function in various tissues. However, the role of IncRNAs in the regulation of myogenesis remains poorly understood. In this study, we identifed a novel muscle-enriched IncRNA called ＇Myolinc （AK142388）＇, which we functionally characterized in the C2C12 myoblast cell line. Myolinc is predominately localized in the nucleus, and its levels increase upon induction of the differ-entiation. Knockdown of Myolinc impairs the expression of myogenic regulatory factors and formation of multi-nucleated myotubes in cultured myoblasts. Myolinc also regulates the expression of Filipl in a cis-manner. Similar to MyoUnc, knockdown of FiUpl inhi-bits myogenic differentiation. Furthermore, Myolinc binds to TAR DNA-binding protein 43 （TDP-43）, a DNA/RNA-binding protein that regulates the expression of muscle genes （e.g. Actal and MyoD）. Knockdown of TDP-43 inhibits myogenic differentiation. We also show that Myolinc-TDP-43 interaction is essential for the binding of TDP-43 to the promoter regions of muscle marker genes. Finally, we show that silencing of Myolinc inhibits skeletal muscle regeneration in adult mice. Altogether, our study identifies a novel IncRNA that controls key regulatory networks of myogenesis.

关键词： long non-coding RNA skeletal muscle myoblasts differentiation transcriptional regulation

Measurement of the integrated luminosity of the Phase 2 data of the Belle Ⅱ experiment

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Chinese Physics C 2020年第2期44卷 1-12页

作者： F.Abudinén I.Adachi P.Ahlburg H.Aihara N.Akopov A.Aloisio F.Ameli L.Andricek N.Anh Ky D.M.Asner H.Atmacan T.Aushev V.Aushev T.Aziz K.Azmi V.Babu S.Baehr S.Bahinipati A.M.Bakich P.Bambade Sw.Banerjee S.Bansal V.Bansal M.Barrett J.Baudot A.Beaulieu J.Becker P.K.Behera J.V.Bennett E.Bernieri F.U.Bernlochner M.Bertemes M.Bessner S.Bettarini V.Bhardwaj F.Bianchi T.Bilka S.Bilokin D.Biswas G.Bonvicini A.Bozek M.Bračko P.Branchini N.Braun T.E.Browder A.Budano S.Bussino M.Campajola L.Cao G.Casarosa C.Cecchi D.Červenkov M.-C.Chang P.Chang R.Cheaib V.Chekelian Y.Q.Chen Y.-T.Chen B.G.Cheon K.Chilikin H.-E.Cho K.Cho S.Cho S.-K.Choi S.Choudhury D.Cinabro L.Corona L.M.Cremaldi S.Cunliffe T.Czank F.Dattola E.De La Cruz-Burelo G.De Nardo M.De Nuccio G.De Pietro R.de Sangro M.Destefanis S.Dey A.De Yta-Hernandez F.Di Capua S.Di Carlo J.Dingfelder Z.Doležal I.Domínguez Jiménez T.V.Dong K.Dort S.Dubey S.Duell S.Eidelman M.Eliachevitch T.Ferber D.Ferlewicz G.Finocchiaro S.Fiore A.Fodor F.Forti A.Frey B.G.Fulsom M.Gabriel E.Ganiev M.Garcia-Hernandez R.Garg A.Garmash V.Gaur A.Gaz U.Gebauer A.Gellrich J.Gemmler T.Geßler R.Giordano A.Giri B.Gobbo R.Godang P.Goldenzweig B.Golob P.Gomis P.Grace W.Gradl E.Graziani D.Greenwald C.Hadjivasiliou S.Halder K.Hara T.Hara O.Hartbrich K.Hayasaka H.Hayashii C.Hearty M.T.Hedges I.Heredia de la Cruz M.Hernández Villanueva A.Hershenhorn T.Higuchi E.C.Hill H.Hirata M.Hoek S.Hollitt T.Hotta C.-L.Hsu Y.Hu K.Huang T.Iijima K.Inami G.Inguglia J.Irakkathil Jabbar A.Ishikawa R.Itoh M.Iwasaki Y.Iwasaki S.Iwata P.Jackson W.W.Jacobs D.E.Jaffe E.-J.Jang H.B.Jeon S.Jia Y.Jin C.Joo J.Kahn H.Kakuno A.B.Kaliyar G.Karyan Y.Kato T.Kawasaki H.Kichimi C.Kiesling B.H.Kim C.-H.Kim D.Y.Kim S.-H.Kim Y.K.Kim Y.Kim T.D.Kimmel K.Kinoshita C.Kleinwort B.Knysh P.Kodyš T.Koga I.Komarov T.Konno S.Korpar D.Kotchetkov N.Kovalchuk T.M.G.Kraetzschmar P.Križan R.Kroeger J.F.Krohn P.Krokovny W.Kuehn T.Kuhr M.Kumar R.Kumar K.Kumara S.Kurz A.Kuzmin Y.-J.Kwon S.Lacaprara Y.-T.Lai C.La Licata K.Lalwani L.Lanceri J.S.Lange K.Lautenbach I.-S.Le Beihang university Beijing 100191 Brookhaven National Laboratory UptonNew York 11973 Budker Institute of Nuclear Physics SB RAS Novosibirsk 630090 Centro de Investigacion y de Estudios Avanzados del Instituto Politecnico Nacional Mexico City 07360 Faculty of Mathematics and Physics Charles University12116 Prague Chiba university Chiba 263-8522 Consejo Nacional de Ciencia y Tecnología Mexico City 03940 Deutsches Elektronen–Synchrotron 22607 Hamburg Duke university DurhamNorth Carolina 27708 Earthquake Research Institute University of TokyoTokyo 113-0032 Forschungszentrum Jülich 52425 Jülich Department of Physics Fu Jen Catholic UniversityTaipei 24205 Key Laboratory of Nuclear Physics and Ion-beam Application(MOE)and Institute of Modern Physics Fudan UniversityShanghai 200443 II.Physikalisches Institut Georg-August-Universität Göttingen37073 Göttingen Gifu university Gifu 501-1193 The Graduate university for Advanced Studies(SOKENDAI) Hayama 240-0193 Gyeongsang National university Jinju 52828 Department of Physics and Institute of Natural Sciences Hanyang UniversitySeoul 04763 High Energy Accelerator Research Organization(KEK) Tsukuba 305-0801 J-PARC Branch KEK Theory CenterHigh Energy Accelerator Research Organization(KEK)Tsukuba 305-0801 Indian Institute of Science Education and Research Mohali SAS Nagar140306 Indian Institute of Technology Bhubaneswar Satya Nagar 751007 Indian Institute of Technology Hyderabad Telangana 502285 Indian Institute of Technology Madras Chennai 600036 Indiana university BloomingtonIndiana 47408 Institute for High Energy Physics Protvino 142281 Institute of High Energy Physics Vienna 1050 Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049 Institute of Particle Physics(Canada) VictoriaBritish Columbia V8W 2Y2 Institute of Physics Hanoi Instituto de Fisica Corpuscular Paterna 46980 INFN Laboratori Nazionali di Frascati I-00044 Frascati INFN Sezione di Napoli I-80126 Napoli INFN Sezione di Padova I-35131 Padova INFN Sezione di Perugia I-06123 Perugia

From April to July 2018,a data sample at the peak energy of the T(4 S) resonance was collected with the Belle Ⅱ detector at the SuperKEKB electron-positron *** is the first data sample of the Belle Ⅱ *** Bhabha and digamma events,we measure the integrated luminosity of the data sample to be(496.3±0.3±3.0) pb-1,where the first uncertainty is statistical and the second is *** work provides a basis for future luminosity measurements at Belle Ⅱ.

关键词： luminosity Bhabha digamma Belle II