检索结果-南通市图书馆

Smoothness of invariant manifolds and foliations for in nite dimensional random dynamical systems--Dedicated to Professor Shantao Liao

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Science China Mathematics 2020年第9期63卷 1877-1912页

作者： Jun Shen Kening Lu Weinian Zhang Department of Mathematics Sichuan UniversityChengdu 610064China Department of Mathematics Brigham Young UniversityProvoUT 84602USA

In this paper,we investigate the smoothness of invariant manifolds and foliations for random dynamical systems with nonuniform pseudo-hyperbolicity in Hilbert *** discuss on the effect of temperedness and the spectral gaps in the nonuniform pseudo-hyperbolicity so as to prove the existence of invariant manifolds and invariant foliations,which preserve the CN,τ;(ω)Holder smoothness of the random system in the space variable and the measurability of the random system in the sample ***,we also prove that the stable foliation is CN-1;(ω)in the base point.

关键词： random dynamical system invariant manifold invariant foliation pseudo-hyperbolicity measurability

The evolving landscape of prostate cancer stem cell: Therapeutic implications and future challenges

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Urology 2016年第4期3卷 203-210页

作者： Eun-Jin Yun U-Ging Lo Jer-Tsong Hsieh Department of Urology UT Southwestern Medical CenterDallasTXUSA

Prostate cancer(PCa)is the most common cause of malignancy in males and the second leading cause of cancer mortality in United *** treatments for PCa include surgery,radiotherapy,and androgen-deprivation ***,PCa relapses to an advanced castration-resistant PCa(CRPC)that becomes a systematic disease and ***,identifying cellular components and molecular mechanisms that drive aggressive PCa at early stage is critical for disease prognosis and therapeutic *** potential strategy for aggressive PCa is to target cancer stem cells(CSCs)that are identified by several unique characteristics such as immortal,self-renewal,and ***,CSC is believed to be a major factor contributing to resistance to radiotherapy and conventional ***,CSCs are thought to be the critical cause of metastasis,tumor recurrence and cancer-related death of multiple cancer types,including *** this review,we discuss recent progress made in understanding prostate cancer stem cells(PCSCs).We focus on the therapeutic strategies aimed at targeting specific surface markers of CSCs,the key signaling pathways in the maintenance of self-renewal capacity of CSCs,ATP-binding cassette(ABC)transporters that mediate the drug-resistance of CSCs,dysregulated microRNAs expression profiles in CSCs,and immunotherapeutic strategies developed against PCSCs surface markers.ª2016 Editorial Office of Asian Journal of *** and hosting by Elsevier *** is an open access article under the CC BY-NC-ND license(http://***/licenses/by-nc-nd/4.0/).

关键词： Prostate cancer Cancer stem cell Normal stem cell

Muscle force and movement variability before and after total knee arthroplasty: A review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Orthopedics 2014年第2期5卷 69-79页

作者： Jessica W Smith Jesse C Christensen Robin L Marcus Paul C LaStayo Department of Bioengineering University of Utah Salt Lake City UT 84108-1290 United States Department of Physical Therapy University of Utah Salt Lake City UT 84108-1290 United States Department of Orthopedics University of Utah Salt Lake City UT 84108-1290 United States Department of Exercise and Sport Science University of Utah Salt Lake City UT 84108-1290 United States

Variability in muscle force output and movement variability are important aspects of identifying individuals with mobility deficits, central nervous system impairments, and future risk of falling. This has been investigated in elderly healthy and impaired adults, as well as in adults with osteoarthritis(OA), but the question of whether the same correlations also apply to those who have undergone a surgical intervention such as total knee arthroplasty(TKA) is still being investigated. While there is a growing body of literature identifying potential rehabilitation targets for individuals who have undergone TKA, it is important to first understand the underlying post-operative impairments to more efficiently target functional deficits that may lead to improvedlong-term outcomes. The purpose of this article is to review the potential role of muscle force output and movement variability in TKA recipients. The narrative review relies on existing literature in elderly healthy and impaired individuals, as well as in those with OA before and following TKA. The variables that may predict longterm functional abilities and deficits are discussed in the context of existing literature in healthy older adults and older adults with OA and following TKA, as well as the role future research in this field may play in providing evidence-based data for improved rehabilitation targets.

关键词： Osteoarthritis Elderly Total knee arthroplasty Movement variability

Analytic time-of-flight positron emission tomography reconstruction: threedimensional case

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Visual Computing for Industry,Biomedicine,and Art 2020年第1期3卷 39-52页

作者： Gengsheng L.Zeng Ya Li Qiu Huang Department of Engineering Utah Valley University800 West University ParkwayOremUT 84058USA Department of Radiology and Imaging Sciences University of Utah729 Arapeen DriveSalt Lake CityUT 84108USA Department of Mathematics Utah Valley University800 West University ParkwayOremUT 84058USA School of Biomedical Engineering Shanghai Jiaotong UniversityShanghai 200240China

In a positron emission tomography(PET)scanner,the time-of-flight(TOF)information gives us rough event position along the line-of-response(LOR).Using the TOF information for PET image reconstruction is able to reduce image *** state-of-the-art TOF PET image reconstruction uses iterative *** study introduces an analytic TOF PET algorithm that focuses on three-dimensional(3D)*** proposed algorithm is in the form of backprojection filtering,in which the backprojection is performed first by using a time-resolution profile function,and then a 3D filter is applied to the backprojected *** the list-mode data,the backprojection is carried out in the event-by-event fashion,and the timing resolution determined weighting function is used along the projection *** simulations are carried out to verify the feasibility of the proposed algorithm.

关键词： Positron emission tomography Time-of-flight Analytic reconstruction

维普期刊数据库

A study of solid ramjet fuel containing boron–magnesium mixtures

在线全文

学校读者我要写书评

暂无评论

Propulsion and Power Research 2017年第4期6卷 243-252页

作者： Eric T.Sandall Joseph Kalman John N.Quigley Scott Munro Trevor D.Hedman College of Science and Engineering Southern Utah UniversityCedar CityUT 84720USA Naval Air Warfare Center Weapons Division 1 Administration CircleChina LakeCA 93555USA

Solid fuel ramjets (SFRJ) are known for their operational simplicity and high specific impulse. The performance of the SFRJ propulsion system is directly tied to the energy density and combustion behavior of the fuel. A typical solid fuel used in a ramjet application is a collection of metal particles suspended in a polymeric binder. Boron is the ubiquitous candidate when considering metal additives for fuels due to an impressive 122.5 kJ/cm3 energy density. However, boron requires long residence times in combustors due to its high melting and boiling points. Magnesium appears to be a natural complement to boron;while possessing a lower energy density (42.1 kJ/cm3), it burns with a high flame temperature and readily reacts in combustion with a low melting point. In this study, several HTPB–boron–magnesium fuels are studied on a small scale to evaluate performance for ramjet application. Holography experiments are conducted, as well as laser ignition tests, to study particle behavior just above the fuel surface. Small, center-perforated fuel grains are examined in a direct-connect SFRJ test stand configuration to measure ignition temperatures and performance parameters. Combustion efficiency of the HTPB–boron–magnesium fuel is found to significantly increase for one of the fuels studied.

关键词： Boron Magnesium Holography Solid fuel ramjet Hydroxyl terminated polybutadiene

Epidemiology of age-related macular degeneration (AMD): associations with cardiovascular disease phenotypes and lipid factors

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Eye and Vision 2016年第1期3卷 263-282页

作者： Katie L.Pennington Margaret M.DeAngelis Department of Ophthalmology John A.Moran Eye CenterUniversity of UtahSalt Lake CityUTUSA

Age-related macular degeneration(AMD)is the leading cause of irreversible blindness in adults over 50 years ***,epidemiological,and molecular studies are beginning to unravel the intricate mechanisms underlying this complex disease,which implicate the lipid-cholesterol pathway in the pathophysiology of disease development and *** of the genetic and environmental risk factors associated with AMD are also associated with other complex degenerative diseases of advanced age,including cardiovascular disease(CVD).In this review,we present epidemiological findings associating AMD with a variety of lipid pathway genes,cardiovascular phenotypes,and relevant environmental *** a number of studies showing significant associations between AMD and these lipid/cardiovascular factors,results have been mixed and as such the relationships among these factors and AMD remain *** is imperative that researchers not only tease out the various contributions of such factors to AMD development but also the connections between AMD and CVD to develop optimal precision medical care for aging adults.

关键词： Atherosclerosis Hypertension Retina Statins Stroke Cholesterol Obesity BMI Antioxidants Genetic association

Calcium channels and their role in regenerative medicine

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Stem Cells 2021年第4期13卷 260-280页

作者： Nassem Ahamad Brij B Singh School of Dentistry UT Health Science Center San AntonioSan AntonioTX 78257United States

Stem cells hold indefinite self-renewable capability that can be differentiated into all desired cell *** on their plasticity potential,they are divided into totipotent(morula stage cells),pluripotent(embryonic stem cells),multipotent(hematopoietic stem cells,multipotent adult progenitor stem cells,and mesenchymal stem cells[MSCs]),and unipotent(progenitor cells that differentiate into a single lineage)*** bone marrow is the primary source of multipotent stem cells in adults,other tissues such as adipose tissues,placenta,amniotic fluid,umbilical cord blood,periodontal ligament,and dental pulp also harbor stem cells that can be used for regenerative *** addition,induced pluripotent stem cells also exhibit fundamental properties of self-renewal and differentiation into specialized cells,and thus could be another source for regenerative *** diseases including neurodegenerative diseases,cardiovascular diseases,autoimmune diseases,virus infection(also coronavirus disease 2019)have limited success with conventional medicine,and stem cell transplantation is assumed to be the best therapy to treat these ***,MSCs,are by far the best for regenerative medicine due to their limited immune modulation and adequate tissue ***,MSCs have the potential to migrate towards the damaged area,which is regulated by various factors and signaling *** studies have shown that extracellular calcium(Ca^(2+))promotes the proliferation of MSCs,and thus can assist in transplantation ***^(2+)signaling is a highly adaptable intracellular signal that contains several components such as cell-surface receptors,Ca^(2+)channels/pumps/exchangers,Ca^(2+)buffers,and Ca^(2+)sensors,which together are essential for the appropriate functioning of stem cells and thus modulate their proliferative and regenerative capacity,which will be discussed in this review.

关键词： Ca^(2+)signaling Ca^(2+)channels Transient receptor potential channel 1/Orai1 stem cells Regenerative medicine Stem cells

Bipolar disorder in the International Classification of Diseases-Eleventh version:A review of the changes,their basis,and usefulness

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Psychiatry 2022年第12期12卷 1335-1355页

作者： Subho Chakrabarti Department of Psychiatry Postgraduate Institute of Medical Education and Research(PGIMER)Chandigarh 160012UTIndia

The World Health Organization’s 11^(th)revision of the International Classification of Diseases(ICD-11)including the chapter on mental disorders has come into effect this *** review focuses on the“Bipolar or Related Disorders”section of the ICD-11 *** describes the benchmarks for the new version,particularly the foremost principle of clinical *** alterations made to the diagnosis of bipolar disorder(BD)are evaluated on their scientific basis and clinical *** change in the diagnostic requirements for manic and hypomanic episodes has been much *** the current criteria have achieved an optimum balance between sensitivity and specificity is still not *** ICD-11 definition of depressive episodes is substantially different,but the lack of empirical support for the changes has meant that the reliability and utility of bipolar depression are relatively *** the Diagnostic and Statistical Manual of Mental Disorders,5th edition(DSM-5),the ICD-11 has retained the category of mixed *** the concept of mixed episodes in the ICD-11 is not perfect,it appears to be more inclusive than the DSM-5 ***,there are some uncertainties about the guidelines for the subtypes of BD and cyclothymic *** initial results on the reliability and clinical utility of BD are promising,but the newly created diagnostic categories also appear to have some *** further improvement and research are needed,the focus should now be on facing the challenges of implementation,dissemination,and education and training in the use of these guidelines.

关键词： ICD-11 guidelines Bipolar disorder utility Reliability

Simulating the Hadamard gate in the Fibonacci disk code for universal topological quantum computation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Innovation 2023年第6期4卷 9-10页

作者： Yong-Shi Wu Department of Physics and Astronomy University of UtahSalt Lake CityUT 84112USA

The 21st century is widely believed to be a century of information *** particular,of quantum information processing,including quantum communi-cation and quantum *** is well known that quantum states are generally fragile,in the sense that quantum coher ence and entanglement needed for information processing cannot be kept for a sufficiently long time due to un-avoidable noises and environmental ***,this problem may be overcome by exploring the so-called topological states of matter,whose physical properties,at least some of the main ones to be used,are robust against disorders and variations in *** emerged the research field of topological,or fault tolerant,quantum computation.

关键词： computation. quantum topological