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Spatial and Temporal Changes of Floating Population in China Between 1990 and 2000

Chinese Geographical Science 2007年第2期17卷 99-109页

作者： LIU Chen Kuninori OTSUBO WANG Qinxue Toshiaki ICHINOSE Sadao ISHIMURA National Institute for Environment Studies 16-20nogawa Tsukuba Ibaraki 305-8506 Japan tsurumi university School of Dental Medicine 2-1-3 Tsurumi Tsurumi Yokohama 230-8501 Japan

By studying the county-level census data of 1990 and 2000, we analyzed the spatial and temporal changes in the floating population in China between 1990 and 2000. The results of the analysis revealed the following characteris- tics. First, the spatial distribution of the migrants (referred to as 'floaters' in this paper) became increasingly concentrated in the cities during the 1990s. Second, the number of floaters increased rapidly during this period, and the area in which the floaters settled expanded quickly into four population explosion belts: the coast, the Changjiang River Delta, the Beijing-Guangzhou Railway and national border belts. Third, the number of inter-province floaters increased rapidly and exceeded that of intra-province floaters in the 1990s. In addition, to obtain a quantitative relationship between the number of floaters and 10 socio-economic variables by using statistical methods and also to find the chiefly important pulling factors of the migration destination, the authors selected approximately 100 cities with the largest population of floaters. Consequently, we found that four factors-GDP, passenger trips per 10,000 persons, per capita GDP and foreign direct investment-could provide an explanation for 83.7% of the number of floaters in 2000. The GDP showed the highest correlation with the number of floaters, suggesting that a highly developed economy is the most important factor that attracts floaters. Furthermore, a fairly close relationship between the number of floaters and the GDP was also found in 2000 for all the counties.

关键词：中国流动人口人口普查人口结构

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Detection accuracy for epithelial dysplasia using an objective autofluorescence visualization method based on the luminance ratio

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International Journal of Oral Science 2017年第4期9卷 200-209页

作者： nanami yamamoto koji kawaguchi hisako fujihara mitsuhiko hasebe yuta kishi masaaki yasukawa kenichi kumagai yoshiki hamada department of oral and maxillofacial surgery school of dental medicinetsurumi universityYokohamaJapan department of oral hygiene tsurumi junior collegeYokohamaJapan

The autofluorescence visualization method （AVM） uses blue excitation light to assist in the diagnosis of epithelial dysplasia. It detects epithelial dysplasia as a black area, which is known as fluorescence visualization loss （FVL）. In this study, we evaluated the detection accuracy for epithelial dysplasia of the tongue using the objective AVM and assessed its possible clinical utility. Seventy-nine tongue specimens clinically suspected to have leukoplakia or squamous cell carcinoma （SCC） were analyzed. First, the AVM was subjectively performed using the Visually Enhanced Lesion scope （VELscope）, and the iodine-staining method was then performed. After biopsy, the histopathological results and the luminance ratio between the lesion and healthy tissue were compared, and a receiver operating characteristic curve was created. The cutoff value for the objective AVM was determined; the lesion was considered FVL-positive or -negative when the luminance ratio was higher or lower than the cutoff value, respectively. The histopathological diagnoses among the 79 specimens were SCC （n = 30）, leukoplakia with dysplasia （n = 34）, and leukoplakia without dysplasia （n= 15）. The cutoff value of the luminance ratio was 1.62, resulting in 66 FVL-positive and 13 FVL-negative specimens. The luminance ratio was significantly higher in the epithelial dysplasia-positive than -negative group （P〈O.O00 1）. The objective AVM showed much higher consistency between histopathological results than did the two methods （kappa statistic = 0.656）. In conclusion, objective autofluorescence visualization has a potential as an auxiliary method for diagnosis of epithelial dysplasia.

关键词： autofluorescence epithelial dysplasia oral cancer Visually Enhanced Lesion scope

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Using eye drops in compliance may improve the symptoms and quality of life in patients with seasonal allergic conjunctivitis: analysis of a two-season web survey

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International Journal of Ophthalmology(English edition) 2023年第6期16卷 988-991页

作者： Asako Kodama Dogru Murat Hiroshi Fujishima Kazumi Fukagawa Department of Ophthalmology Eiju General HospitalTokyo 110-8645Japan Department of Ophthalmology Tsurumi University School of Dental MedicineKanagawa 230-0063Japan Ryogoku Eye Clinic Tokyo 130-0062Japan

Dear Editor,Allergic conjunctivitis is the most common ocular surface allergic disease, affecting more than 30% of the population[1-2]. In the immediate phase of the allergic reactions(type Ⅰ) in patients with seasonal allergic conjunctivitis(SAC), the binding of antigen with the reaginic antibody leads to the formation and release of chemical mediators, such as histamines, in the local anaphylactic reaction[3].

关键词： allergic patients seasonal

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CHANGES IN AIRWAY SPACE FOLLOWING MANDIBULAR SETBACK USING SAGITTAL SPLIT OSTEOTOMY AND RIGID INTERNAL FIXATION

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Chinese Medical Sciences Journal 1997年第2期12卷 96-101页

作者：毛驰 Aruga Susumu Matsuura Masaroh Seto Kanichi First Department of Oral and Maxillofacial Surgery Tsurumi University School of DentistryYokohama 230Japan First Department of Oral and Maxillofacial Surgery Tsurumi University School of DentistryYokohama 230Japan

The changes in airway space following mandibular setback using sngittal split osteotomy and rigid internal fixation were studied in 28 Japanese patients with mandibular prognathism. The correlation between the amount of mandibular setback and airway space changes,as well as the correlation between the amount of airway space changes and relapse of pognion point during the following-up period were also studied. Lateral cephalometric radiographs were taken immediately before and shortly after surgery as well as 5 to 12 months postoperation. The cephalometrlc evaluations of airway space width and area were based on stable craniofacial landmarks. The mean setback of mandible was 8.3 mm in the right slde,and 8. 2 mm in the left side. The mean amount of relapse of pogonion point during the following-up period was 0, 52 ram horlaontally ,and 0.92 mm vertically. A significant decrease in airway space width and area ,espacially in the lower part of airway space was found following mandibular setback shortly after surgery. Although there was some increase both in airway space width and area during the followlng-up period,they did not increase to their original values. This suggents that the narrowing of airway space following mandibular setback using sagittal split osteotomy can be permanent. No significant correlation was found between the amount of mandibular setback and airway space changes. Since the relapse of pogonion point during the following-up period was too smell,there is no significant correlation between it and the amount of airway space changes.

关键词：内固定凸颚手术治疗截骨术复发

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Overexpression of INCREASED CAMBIAL ACTIVITY, a putative methyltransferase, increases cambial activity and plant growth

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Journal of Integrative Plant Biology 2016年第11期58卷 874-889页

作者： Hyunsook Kim Mikiko Kojima Daeseok Choi Soyoung Park Minami Matsui Hitoshi Sakakibara Ildoo Hwang Department of Life Sciences Pohang University of Science and Technology Pohang 790-784 Korea Synthetic Genomics Research Team Biomass Research Cooperation Division (BMEP) RIKEN Center for Sustainable Resource Science (CSRS) Tsurumi Yokohama 230-0045 Japan Riken Center for Sustainable Resource Science (CSRS) Tsurumi Yokohama 230-0045 Japan

Cambial activity is a prerequisite for secondary growth in plants; however, regulatory factors controlling the activity of the secondary meristem in radial growth remain elusive. Here, we identified INCREASED CAMBIAL ACTIVITY （ICA）, a gene encoding a putative pectin methyltransferase, which could function as a modulator for the meristematic activity of fascicular and interfascicular cambium in Arabidopsis. An overexpressing transgenic line, 35S：＇1CA, showed accelerated stern elongation and radial thickening, resulting in increased accumulation of biomass, and increased levels of cytokinins （CKs） and gibberellins （GAs）. Expression of genes encoding pectin methylesterases involved in pectin modification together with pectin methyltransferases was highly induced in 355：：ICA, which might contribute to an increase of methanol emission as a byproduct in 35S：ICA. Methanol treatment induced the expression of GA- or CK-responsive genes and stimulated plant growth. Overall, we propose that ectopic expression of ICA increases cambial activity by regulating CK and GA homeostasis, and methanol emission, eventually leading to stem elongation and radial growth in the inflorescence stem.

关键词： Cambial activity cytokinin gibberellin methanol methyltransferase pectin shoot growth

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Novel Bioactive Glass as a Potential Clinical Appliance

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材料科学与工程（中英文A版） 2017年第3期7卷 111-120页

作者： Hitoshi Oguchi Department of Geriatric Dentistry Tsurumi University School of Dental Medicine 2-1-3 Tsurumi Tsurumi-ku Yokohama City 850-0051 Japan

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Clinical factors influencing the resting and stimulated salivary flow

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Open Journal of Stomatology 2012年第2期2卷 103-109页

作者： Shigeo Yamachika Ken Yamamoto Yoshiaki Nomura Hiroyuki Yamada Ichiro Saito Yoichi Nakagawa Department of Clinical Pathophysiology School of Dental MedicineTsurumi UniversityYokohamaJapan Department of Oral Medicine and Stomatology School of Dental MedicineTsurumi UniversityYokohamaJapan Department of Geriatric Dentistry School of Dental MedicineTsurumi UniversityYokohamaJapan Department of Translational Research School of Dental MedicineTsurumi UniversityYokohamaJapan Department of Oral and Maxillofacial Surgery School of Dental MedicineTsurumi UniversityYokohamaJapan Department of Pathology School of Dental MedicineTsurumi UniversityYokohamaJapan

Objective: The objective of this study was to examine the clinical and immunological factors influ encing sialometry in xerostomia patients. Method: The association between sialometry and other clinical examinations were investigated in a cross-sectional study. A total of 179 dry mouth patients showing hyposalivation who underwent a clinical examination were enrolled in this study. Multiple regression analyses were employed to examine the relative con-tributions of clinical and immunological factors including age, gender, parotid sialography, labial Salivary gland biopsy, anti-Ro/SS-A antibodies, and anti-La/SS-B antibodies to the resting (RSF) or stimulated saliva flow rate (SSF). Results: An increase of the stage of sialography, the grade of a labial biopsy, and the presence of anti-La/SS-B antibody had a significant correlation with a decrease of sialometry. Results of the multiple regression analysis showed that age (standardized coefficient = -0.244), grade of lip biopsy (-0.189), and anti-SS-B antibody (-0.171), were significantly associated with the RSF. The stage of sialography (?0.423) and age (-0.169) were significantly related to the sialometry in the SSF according to a multiple regression analysis. Conclusion: The results of this study suggest that the measurement of RSF reflects the immunological factors and SSF reflects the damage to the parotid gland.

关键词： Xerostomia Sialometry Sialography Labial Minor Salivary Gland Biopsy Sjogren’s Syndrome

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Upregulation of epidermal growth factor receptor 4 in oral leukoplakia

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International Journal of Oral Science 2013年第1期5卷 14-20页

作者： Hiroshi Kobayashi Kenichi Kumagai Akito Gotoh Takanori Eguchi Hiroyuki Yamada Yoshiki Hamada Satsuki Suzuki Ryuji Suzuki Department of Oral and Maxillofacial Surgery Tsurumi University Department of Rheumatology and Clinical Immunology Clinical Research Center for Rheumatology and AllergySagamihara National HospitalNational Hospital Organization Section of Biological Science Research Center for Odontology Nippon Dental University School of Dentistry

In the present study,we investigate the expression profile of the epidermal growth factor receptor family,which comprises EGFR/ ErbBl,HER2/ErbB2,HER3/ErbB3 and HER4/ErbB4 in oral leukoplakia(LP).The expression of four epidermal growth factor receptor (EGFR) family genes and their ligands were measured in LP tissues from 14 patients and compared with levels in 10 patients with oral lichen planus(OLP) and normal oral mucosa(NOM) from 14 healthy donors by real-time polymerase chain reaction(PCR) and *** mRNA coexpression of ErbBl,ErbB2,ErbB3and ErbB4 was detected in LP *** of the receptors,only ErbB4 mRNA and protein was more highly expressed in LP compared with NOM *** were strongly expressed by epithelial keratinocytes in LP lesions,as shown by *** the ligands,the mRNA of Neuregulin2 and 4 were more highly expressed in OLP compared with NOM ***,enhanced ErbB4 on the keratinocytes and synchronous modulation of EGFR family genes may contribute to the pathogenesis and carcinogenesis of LP.

关键词： epidermal growth factor receptor immunohistochemistry oral leukoplakia quantitative real-time polymerase chain reaction

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Metabolomic Screening Applied to Rice FOX Arabidopsis Lines Leads to the Identification of a Gene-Changing Nitrogen Metabolism

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Molecular Plant 2010年第1期3卷 125-142页

作者： Doris Albinsky Miyako Kusano Mieko Higuchi Naomi Hayashi Makoto Kobayashi Atsushi Fukushima Masaki Mori Takanari Ichikawa Keiko Matsui Hirofumi Kuroda Yoko Horii Yuko Tsumoto Hitoshi Sakakibara Hirohiko Hirochika Minami Matsui Kazuki Saito RIKEN Plant Science Center Tsurumi-ku Yokohama 230-0045 Japan National Institute of Agrobiological Sciences Tsukuba 305-8602 Japan Graduate School of Pharmaceutical Sciences Chiba University Inage-ku Chiba 263-8522 Japan

Plant metabolomics developed as a powerful tool to examine gene functions and to gain deeper insight into the physiology of the plant cell. In this study, we screened Arabidopsis lines overexpressing rice full-length （FL） cDNAs （rice FOX Arabidopsis lines） using a gas chromatography-time-of-flight mass spectrometry （GC-TOF/MS）-based technique to identify rice genes that caused metabolic changes. This screening system allows fast and reliable identification of candi- date lines showing altered metabolite profiles. We performed metabolomic and transcriptomic analysis of a rice FOX Ara- bidopsis line that harbored the FL cDNA of the rice ortholog of the Lateral Organ Boundaries （LOB） Domain （LBD）/ Asymmetric Leaves2-1ike （ASL） gene of Arabidopsis, At-LBD37/ASL39. The investigated rice FOX Arabidopsis line showed prominent changes in the levels of metabolites related to nitrogen metabolism. The transcriptomic data as well as the results from the metabolite analysis of the Arabidopsis At-LBD37/ASL39-overexpressor plants were consistent with these findings. Furthermore, the metabolomic and transcriptomic analysis of the Os-LBD37/ASL39-overexpressing rice plants indicated that Os-LBD37/ASL39 is associated with processes related to nitrogen metabolism in rice. Thus, the combination of a metabolomics-based screening method and a gain-of-function approach is useful for rapid characterization of novel genes in both Arabidopsis and rice.

关键词： Metabolite profiling GC-TOF/MS rice FOX Arabidopsis lines transcript profiling LBD37/ASL39 nitrogenmetabolism.

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A CLINICAL EVALUATION OF ITI-IMPLANTS TO BE INSTALLED IN THE MAXILLA

A CLINICAL EVALUATION OF ITI-IMPLANTS TO BE INSTALLED IN THE...

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第二届中国国际暨第五届全国口腔颌面外科学术会议

作者： T．NOMURA M．MATSUURA K．SETO FIRST DEPARTMENT OF OMS SCHOOL OF DENTISTRY tsurumi university JAPAN FIRST DEPARTMENT OF OMS SCHOOL OF DENTISTRY tsurumi university JAPAN FIRST DEPARTMENT OF OMS SCHOOL OF DENTISTRY tsurumi university JAPAN

The most essential requirements for success of implant installation in the maxilla should be to apply implants of longer length which are supported by both the alveolar ridge and the compact bone of the maxillary sinus floor,or nasal floor. Therefore,it is very important to know the outline of the maxilla during preoperative *** AND MATHODS:From April 1993 to December 1997,75 patients (17 male and 57 female) who received 168 implants were

关键词： ITI A CLINICAL EVALUATION OF ITI-IMPLANTS TO BE INSTALLED IN THE MAXILLA

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