检索结果-南通市图书馆

Floating elbow combining ipsilateral distal multiple segmental forearm fractures: A case report

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2021年第14期9卷 3372-3378页

作者： Guo-Hua Huang Jiang-An Tang Tie-Yi Yang Yue Liu Department of Orthopedics Shanghai Pudong New Area Gongli HospitalAffiliated to the Second Military Medical UniversityShanghai 200135China

BACKGROUND Floating elbow along with ipsilateral multiple segmental forearm fracture is a rare and high-energy injury,although elbow dislocation or fracture of the ulna and radius may occur *** SUMMARY We report the case of a 37-year-old woman with open(IIIA)fracture of the right distal humerus with multiple shaft fractures of the ipsilateral radius and ulna with a history of falling from a height of almost 20 m from a *** providing advanced trauma life support,damage control surgery was performed to debride the arm wound and temporarily stabilize the right upper limb with external fixators in the emergency operating ***,one-stage internal fixation of multiple fractures was performed with normal values of biochemical indicators and reduction in limb *** patient achieved good outcome at the 7 mo *** One-or two-stage treatment must be performed according to the type of injury;we efficiently used the“damage control principle.”

关键词： Floating forearm Advanced trauma life support Internal fixation Multiple fractures Open fracture Case report

Lipid levels and insulin resistance markers in patients with colorectal cancer:Propensity score matching analysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2025年第1期17卷 130-142页

作者： Ren-Hao Hu Dong-Yi Yan Ke-Hui Zhang Di Zhang Xi-Mao Cui Xiao-Hua Jiang Shun Zhang Department of Gastrointestinal Surgery Shanghai East HospitalSchool of MedicineTongji UniversityShanghai 200120China School of Medicine Tongji UniversityShanghai 200092China Department of Emergency Medicine Shanghai East HospitalSchool of MedicineTongji UniversityShanghai 200120China

BACKGROUND Colorectal cancer(CRC)is a prevalent malignant neoplasm characterized by subtle early *** To investigate the correlation among serum lipid profiles,the triglyceride-glucose(TyG)index,and the atherosclerotic index(AI)in patients with ***,it explored the clinical diagnostic utility of combining serum lipids with cancer antigens in the context of *** A retrospective analysis encompassed 277 patients with CRC and 1034 healthy *** Following propensity score matching,patients with CRC exhibited significantly reduced levels of serum triglyceride(TG),total cholesterol(TC),high-density lipoprotein cholesterol,and low-density lipoprotein cholesterol(LDL-C),as well as a diminished TyG ***,they displayed elevated AI levels compared to their healthy *** in advanced stages exhibited lower serum levels of TG,TC,and LDL-C compared to those in early *** with positive lymph node metastasis demonstrated reduced levels of TG,LDL-C,and the TyG *** operating characteristic analysis revealed that the combination of the TyG index,carcinoembryonic antigen,and carbohydrate antigen 19-9 yielded the highest positive prediction rate for CRC at 75.3%.CONCLUSION Preoperative serum lipid profiles exhibit a robust association with patients with *** concurrent assessment of multiple serum lipids and cancer antigens effectively enhances the diagnostic accuracy for CRC.

关键词： Colorectal cancer Serum lipids Triglyceride-glucose index Atherosclerotic index Diagnostic marker

Association between autoimmune gastritis and gastric polyps:Clinical characteristics and risk factors

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2025年第1期17卷 73-87页

作者： Jing-Zheng Jin Xiao Liang Shu-Peng Liu Rui-Lan Wang Qing-Wei Zhang Yu-Feng Shen Xiao-Bo Li Division of Gastroenterology and Hepatology Renji HospitalShanghai Jiao Tong University School of MedicineShanghai 200127China Division of Gastroenterology and Hepatology Shanghai Institute of Digestive DiseasesShanghai 200001China Division of Gastroenterology and Hepatology Renji Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200127China Division of Gastroenterology and Hepatology Sichuan Armed Police Corps HospitalLeshan 610041Sichuan ProvinceChina Division of Gastroenterology and Hepatology NHC Key Laboratory of Digestive DiseasesRenji HospitalShanghai Jiao Tong University School of MedicineShanghai 200127China Department of Gastroenterology Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai Institute of Digestive DiseasesShanghai 200127China

BACKGROUND The relationship between autoimmune gastritis(AIG)and gastric polyps(GPs)is not well *** To explore the clinical characteristics and risk factors of AIG with GPs in *** This double center retrospective study included 530 patients diagnosed with AIG from July 2019 to July *** collected clinical,biochemical,serological,and demographic data were of each *** regression analyses,both multivariate and univariate,were conducted to pinpoint independent risk factors for GPs in patients with AIG *** operating characteristic curves were utilized to establish the optimal cutoff values,sensitivity,and specificity of these risk factors for predicting GPs in patients with *** Patients with GPs had a higher median age than those without GPs[61(52.25-69)years vs 58(47-66)years,P=0.006].The gastrin-17 levels were significantly elevated in patients with GPs compared with those without GPs[91.9(34.2-138.9)pmol/mL vs 60.9(12.6-98.4)pmol/mL,P<0.001].Additionally,the positive rate of parietal cell antibody(PCA)antibody was higher in these patients than in those without GPs(88.6%vs 73.6%,P<0.001).Multivariate and univariate analyses revealed that PCA positivity[odds ratio(OR)=2.003,P=0.017],pepsinogen II(OR=1.053,P=0.015),and enterochromaffin like cells hyperplasia(OR=3.116,P<0.001)were significant risk factors for GPs,while pepsinogen I was identified as a protective *** PCA positivity and enterochromaffin like cells hyperplasia are significant risk factor for the development of GPs in patients with *** gastrin-17 levels may also play a role in this *** findings suggest potential targets for further research and therapeutic intervention in managing GPs in patients with AIG.

关键词： Autoimmune gastritis Gastric polyps Neuroendocrine tumor Risk factors Nomogram

Flapless one-knot suture:a novel surgical technique for transscleral fixation of C-loop intraocular lenses

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2023年第5期16卷 736-742页

作者： Qing-Qing Long Bao-Jiang Li Department of Ophthalmology Gongli Hospital of Shanghai Pudong New AreaShanghai 200135China Department of Ophthalmology Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China

AIM:To describe a novel suture approach for transscleral fixation of C-loop intraocular lenses(IOL)and to compare the surgical outcomes with the four-haptics posterior chamber(PC)-IOL ***:We retrospectively analyzed 16 eyes of 16 patients who underwent transscleral fixation of C-loop PCIOLs using a flapless one-knot suture technique,which were followed up for longer than *** this technique,the capsulorless IOL was suspended using a single suture for transscleral fixation of four *** we compared its surgical outcomes and complications with the four-haptics PC-IOLs using the Student's t test and Chi-square ***:Sixteen patients of 16 eyes with a mean age of 58.3±10.1y(42-76y)who received transscleral C-loop IOL implantation due to trauma,vitrectomy,or cataract surgery with inadequate capsule support showed improved visual *** difference was not significant between two IOLs except the surgery time(P>0.05).The mean operation times of C-loop IOL surgery was 24.1±1.83min and 31.3±4.47min of the four-haptics PC-IOL method(P0.05).We did not detect any optic capture,IOL decentration or dislocation,suture exposed,or cystoid macular edema in patients underwent C-loop IOLs ***:The novel flapless one-knot suture technique for transscleral fixation of C-loop IOL is a simple,reliable,and stable technique.

关键词： C-loop intraocular lens implantation lens dislocation transscleral fixation four-haptics intraocular lens

Proteomic identification of proteins in exosomes of patients with atherosclerosis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国病理生理杂志 2016年第8期32卷 1525-1526页

作者： JIANG Mei QUAN Jing ZHANG Heng DING Qian-qian XIANG Meng MENG Dan SUN Ning CHEN Si-feng Department of Neurology Shanghai Pudong New Area Gongli Hospital Department of Physiology and Pathophysiology Fudan University Shanghai Medical College

AIM: Atherosclerosis primarily involved systemic arteries. Luminal surface,a monolayer of endothelial cells,of artery directly exposes to blood and is susceptible to active substances in the blood. Exosomes contain significantly amount of proteins and RNAs. Exosomes can be good and bad for cells,depending on their component. Thus,exosomes may contribute to atherosclerosis by affecting endothelial cells. This study analyzed the relationship of exosome proteins and atherosclerosis. METHODS: Fifty-six patients and healthy subjects were recruited and divided into two comparisons: healthy subjects vs atherosclerosis( HS vs AS),and hypertension vs hypertension plus atherosclerosis( HT vs HT + AS). Serum exosomes were decoded by protein mass spectrometry. The protein profile and function were analyzed by gene ontology( GO). RESULTS: It was found that five child terms repeatedly appeared in"response to stimulus"and "immune system process"of BP of the two categories( HS vs AS and AS vs HT + AS): "positive regulation of innate immune response","immune response-activating signal transduction","activation of innate immune response","innate immune response-activating signal transduction"and "innate immune response activating cell surface receptor signaling pathway". Two child terms repeatedly showed in "binding"of MF of the two categories: "antigen binding"and "enzyme binding". Two proteins,PSMA6 and PSMA7,were repeatedly shown in the two categories. CONCLUSION: GO analysis was utilized for structure hierarchy"tree"to illustrate these proteins involved in various terms in BP,CC and MF. The PPI analysis supplied proteins which may play potentially important roles in AS process. Innate immune system and blood coagulation pathway contribute to AS formation. The proteins,PSMA6,PSMA7 and Annexin A2,may can be the new target proteins for prevention and treatment of AS.

关键词： PSMA

A BBS4 mutation causes autosomal dominant polycystic liver disease

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Genes & Diseases 2024年第1期11卷 72-75页

作者： Yalu Cui Wenping Xu Jinpei Liu Shuqing Liu Wei Huang Yihai Shi Xin Zhang Cuihua Lu Weifen Xie Department of Gastroenterology Changzheng HospitalNaval Medical UniversityShanghai 200003China Department of Gastroenterology Gongli Hospital of Shanghai Pudong New AreaShanghai 200135China Department of Gastroenterology Affiliated Hospital of Nantong UniversityNantong UniversityNantongJiangsu 226001China

Autosomal dominant polycystic liver disease(ADPLD)refers to a condition characterized by the presence of numerous cholangiocytes-lined and fluid-filled cysts in the liver and the absence of polycystic kidney disease.1 Although patients with ADPLD may be asymptomatic,some patients suffer from abdominal pain,gastroesophageal reflux,and nausea,because of hepatomegaly.

关键词： liver polycystic patients

Carcinosarcoma of common bile duct:A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2023年第3期15卷 562-570页

作者： Yao Yao Hong-Gang Xiang Lei Jin Ming Xu Shu-Yan Mao Division of Gastroenterology and Hepatology Shanghai Pudong New Area People’s HospitalShanghai University of Medicine and Health SciencesShanghai 200120China Division of General Surgery Shanghai Pudong New Area People’s HospitalShanghai University of Medicine and Health SciencesShanghai 200120China Division of Pathology Shanghai Pudong New Area People’s HospitalShanghai University of Medicine and Health SciencesShanghai 200120China

BACKGROUND Carcinosarcomas of the common bile duct(CBD)are an extremely rare finding in the clinical *** on a review of 12 literatures,3 cases had the imaging features of *** are prone to distant metastasis,as they possess clinical features of both carcinoma and sarcoma,and generally have with a poor *** to the small number of cases reported,clinical experience in the diagnosis and treatment of the disease is *** SUMMARY The patient was a 75-year-old woman who had experienced recurrent chills with nausea and vomiting for 3 *** tomography,magnetic resonance imaging,endoscopic ultrasonography and endoscopic retrograde cholangiopancreatography led to the diagnosis of malignant tumor of the *** patient ultimately underwent cholecystectomy,CBD resection,and *** pathological examination revealed carcinosarcoma of the CBD,and the latest follow-up showed that the patient is recovering *** on previous case reports,some carcinosarcoma has ossification characteristics in *** it is misdiagnosed as biliary calculi,the use of laser lithotripsy in surgery may lead to tumor *** and narrow band staining of mucosa are very important for *** We herein present a rare case of carcinosarcomas of the CBD,we found the tumours may have imaging features of polypoid growth and ossification only when the sarcomal components are bone differentiation,while show soft tissue shadow when non bone *** of diagnosis depends greatly upon postoperative pathological examination and the adjuvant treatment has not been established,which leads to the poor prognosis.

关键词： Carcinosarcoma Sarcocarcinoma Sarcomatoid carcinoma Extrahepatic bile duct tumor Common bile duct tumor Case report

Postoperative complications of concomitant fat embolism syndrome, pulmonary embolism and tympanic membrane perforation after tibiofibular fracture: A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2021年第2期9卷 476-481页

作者： Jin Shao De-Ce Kong Xin-Hui Zheng Tian-Ning Chen Tie-Yi Yang Department of Orthopedics Pudong New Area Gongli HospitalSchool of Clinical MedicineShanghai UniversityShanghai 200135China Graduate School Ningxia Medical UniversityYinchuan 750004Ningxia Hui Autonomous RegionChina

BACKGROUND Fat embolism syndrome(FES)is a rare disease characterized by pulmonary distress,neurologic symptoms,and petechial rash and seriously threatens human life and *** is still neglected clinically because of the lack of verifiable diagnostic criteria and atypical clinical *** studies on FES with pulmonary embolism(PE)and tympanic membrane perforation have been reported to ***,we report a rare case of concomitant FES,PE and tympanic membrane perforation after surgery in a patient with a tibiofibular *** SUMMARY A 39-year-old man presented with right lower extremity pain due to a car accident while driving a motorbike on the road.X-ray and computed tomography scans revealed a fracture of the right mid-shaft tibia and proximal fibula categorized as a type A2 fracture according to the AO classification.A successful minimally invasive operation was performed 3 d after the ***,the patient developed sudden symptoms of respiratory distress and hearing *** diagnosis was made,and supportive treatments were used at the early stage of *** days after surgery,he presented a clear recovery from respiratory *** outcome of fracture healing was excellent,and his hearing of the left ear was mildly impaired at the last follow-up of 4 *** Concomitant FES,PE and tympanic membrane perforation are very rare but represent potentially fatal complications of trauma or orthopedic surgery and present with predominantly pulmonary *** diagnosis and treatment can reduce the mortality of FES,and prevention is better than a cure.

关键词： Fat embolism syndrome Tibiofibular fracture Pulmonary embolism Tympanic membrane perforation Postoperative complication Case report

Antifibrotic Effect of Total Flavonoids of Astmgali Radix on Dimethylnitrosamine-lnduced Liver Cirrhosis in Rats

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Integrative Medicine 2017年第1期23卷 48-54页

作者： CHENG Yang MAI Jing-yin WANG Mei-feng CHEN Gao-feng PING Jian Shuguang hospital Affiliated to shanghai University of Traditional Chinese Medicine Shanghai 201203China shanghai pudong new area hospital of Traditional Chinese Medicine Shanghai 201299China

Objective：To study the effect of total flavonoids of Astmgali Radix（TFA）on liver cirrhosis induced with dimethylnitrosamine（DMN）in rats,and the effect on peroxisome proliferator-activated receptorγ（PPARγ）,uncoupling protein 2（UCP2）and farnesoid X receptor（FXR）.Methods：Fifty-three Sprague-Dawley rats were randomly divided into a control group（10 rats）and a DMN group（43 rats）.Rats in the DMN group were given DMN for 4 weeks and divided randomly into a model group（14 rats）,a low-dosage TFA group（14 rats）and a high-dosage TFA group（15 rats）in the 3rd *** were given TFA for 4 weeks at the dosage of 15 and 30 mg/kg in the low-and high-TFA groups,*** the end of the experiment blood and liver samples were *** liver function and liver tissue hydroxyproline content were ***-eosin（HE）,Sirus red and immunohistochemical stainings of collagenⅠ,smooth muscle actin（α-SMA）was conducted in paraffinembedded liver tissue *** time polymerase chain reaction（PCR）was adopted to determine PPARγ,UCP2 and FXR m RNA *** blot was adopted to determine protein levels of collagenⅠ,α-SMA,PPARγ,UCP2 and ***：Compared with the model group,TFA increased the ratio of liver/body weight（low-TFA group P〈0.05,high-TFA group P〈0.01）,improved liver biochemical indices（P〈0.01 for ALT,AST,GGT in both groups,P〈0.05 for albumin and TBil in the high-TFA group）and reduced liver tissue hydroxproline content（P〈0.01 in both groups）in treatment groups *** staining showed that TFA alleviated liver pathological changes markedly and Sirus red staining showed that TFA reduced collagen deposition,alleviated formation and extent of liver ***Ⅰandα-SMA immunohistochemical staining showed that staining area and extent markedly decreased in TFA groups compared with the model *** could increase PPARγ,it regulated target UCP2,and FXR levels significantly compared with the model group（in the low-TFA group all P〈0.05,in t

关键词： total flavonoids of Astmgali Radix dimethylnitrosamine liver cirrhosis peroxisome proliferator-activated receptor γ uncoupling protein 2 farnesoid X receptor rat