A BBS4 mutation causes autosomal dominant polycystic liver disease
作者机构:Department of GastroenterologyChangzheng HospitalNaval Medical UniversityShanghai 200003China Department of GastroenterologyGongli Hospital of Shanghai Pudong New AreaShanghai 200135China Department of GastroenterologyAffiliated Hospital of Nantong UniversityNantong UniversityNantongJiangsu 226001China
出 版 物:《Genes & Diseases》 (基因与疾病(英文))
年 卷 期:2024年第11卷第1期
页 面:72-75页
核心收录:
学科分类:0710[理学-生物学] 1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
基 金:supported by the Medical Discipine Construction Project of Pudong Health Committee of Shanghai(No.PWYgf2021-08 to S.Y.H) the National Natural Science Foundation of China(No.82030021 to W.F.X.,82070624 to C.H.L.,and 82000581 to J.P.L.)a the Deep Blue Talent Project of Naval Medical University to W.P.X
主 题:liver polycystic patients
摘 要:Autosomal dominant polycystic liver disease(ADPLD)refers to a condition characterized by the presence of numerous cholangiocytes-lined and fluid-filled cysts in the liver and the absence of polycystic kidney disease.1 Although patients with ADPLD may be asymptomatic,some patients suffer from abdominal pain,gastroesophageal reflux,and nausea,because of hepatomegaly.