检索结果-南通市图书馆

Sedated vs unsedated colonoscopy:A prospective study

World Journal of Gastroenterology 2014年第17期20卷 5113-5118页

作者： Abdulrahman M Aljebreen Majid A Almadi Felix W Leung Gastroenterology Division King Khalid University HospitalKing Saud UniversityRiyadh 11461Saudi Arabia Gastroenterology Division McGill University Health Center McGill University MontrealQuebec H3G 1A4Canada Research and Medical Services Sepulveda Ambulatory Care CenterVeterans Affairs Greater Los Angeles Healthcare Systemand David Geffen School of Medicine at UCLALos AngelesCaliforniaCA 91343United States

AIM:To compare sedated to unsedated colonoscopy in terms of duration,pain and the patient’s willingness to repeat the ***:Consecutive patients who underwent colonoscopies over a 2-year period were invited to *** patients who were to undergo our endoscopy unit were offered sedation with standard intravenous sedatives and analgesics,or an unsedated colonoscopy was *** details were *** patient anxiety level prior to the procedure,time to reach the cecum,total discharge time,patient and endoscopist pain assessments,satisfaction after the examination and the patient’s willingness to return for the same procedure in the future were ***:Among the 403 observed patients,more males were observed in the unsedated group(66.2%vs 55.2%,P=0.04).Additionally,the unsedated group patients were less anxious prior to the procedure(5.1vs 6.0,P<0.01).The colonoscopy completion rates were comparable between the 2 groups(85.9%vs84.2%,P=0.66).The time to reach the cecum was also comparable(12.2 min vs 11.8 min);however,the total discharge times were shorter in the unsedated group(20.7 min vs 83.0 min,P<0.01).Moreover,the average patient pain score(3.4 vs 5.7,P<0.01)was lower in the sedated group,while the satisfaction score(8.8 vs 7.8,P<0.01)was significantly *** was no significant difference,however,between the groups in terms of willingness to repeat the procedure if another was required in the future(83.3%vs 77.3%,P=0.17).CONCLUSION:Unsedated colonoscopy is feasible in willing *** option saves the endoscopy units up to one hour per patient and does not affect the patient willingness to return to the same physician again for additional colonoscopies if a repeated procedure is needed.

关键词： Sedation Colonoscopy Unsedated Screening Endoscopy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A 3-dimensional transoesophageal echocardiography perspective of mitral valve abscess

引用

Journal of Geriatric Cardiology 2020年第2期17卷 124-124页

作者： Pujan Patel Shreya Ghetiya Emil Missov Srinivasan Sattiraju Division of Cardiology Department of Internal MedicineUniversity of FloridaAmbulatory Care Center

An 85-year-old female with history of dementia presented with concern for severe sepsis and was found to have methicillin sensitive staphylococcus aureus bacteremia complicated by atrial *** further workup,a transoesophageal echocardiography(TOE)was *** study revealed a large echogenic density with multiple echolucent areas within the *** was evidence of blood flow in these echolucent areas based on color flow *** mass was intermittently protruding into the left ventricle causing a function mitral *** collective findings on echocardiography,in context of bacteremia,were highly suggestive of mitral valve abscess(Figure 1).

关键词： Endocarditis Three dimensional transoesophageal echocardiography Valvular abscess

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Prevalence of Hypertension and Associated Factors in Patients Living with HIV Followed at the ambulatory Treatment center (CTA) of Fann National University Hospital in Dakar

引用

Health 2017年第4期9卷 727-737页

作者： Ndeye Fatou Ngom Gueye Daye Ka Alioune Badara Tall Kine Ndiaye Abdoul Aziz Ndiaye Viviane Marie Pierre Cisse Aissata Guindo Ndeye Méry Dia Badiane Sylvie Audrey Diop Noel Magloire Manga Cheikh Tidiane Ndour Moussa Seydi ambulatory Treatment center Fann University Teaching Hospital Dakar Senegal Department of Infectious Diseases Fann University Teaching Hospital Dakar Senegal Department of Community Health Alioune Diop University Bambey Senegal

Introduction: The efficacy of antiretroviral therapy in people living with HIV (PLHIV) has been associated with an important increase in metabolic disorders, such as hypertension (HTA). This work allowed us to estimate the prevalence of hypertension in PLHIV and to describe associated factors. Methods: A retrospective, descriptive and analytical study was carried out based on the records of people living with HIV followed at the ambulatory Treatment center (CTA), from January 1st 1998 to 31st, December 2014. The WHO criteria were used to diagnose hypertension. Data entry was performed using ESOPE software and data analysis was done using Epi Info software version 3.5.3. A multiple logistic regression was used to identify the risk factors associated with hypertension. Results: During the study period, 3624 patients followed at CTA were included of which 1184 patients (32.7%) had hypertension. The average age was 47. 3 years ±10.5 years, with a sex ratio of 0.7. The most common opportunistic infections at diagnosis were tuberculosis (14.9%) and oral candidiasis (15.3%). The HIV infection was advanced (stage 3 or 4 of WHO classification) for 39% of cases. Overweight and obesity was found in 19.1%. Only 17.6% were treated by protease inhibitors. Higher average age (OR:1,05;IC [1.04 - 1.05], p = 0.000001), higher average BMI (OR:5,3;IC [3.3 - 8.5], p = 0.00001), WHO clinical stage I-II (OR:1,4;IC [1.2 - 1.6], p = 0.00003), and ARV treatment (OR:2,5;IC [1.7 - 3.7], p = 0.000001) are associated with the occurrence of hypertension. Conclusion: The prevalence of hypertension was high among PLHIV and associated factors were: advanced age, high BMI, WHO clinical stages I and II and antiretroviral therapy. Hence, the interest of a systematic screening of hypertension and others cardiovascular risk factors particularly in patients under ARV antiretroviral therapy.

关键词： Hypertension (HTA) HIV Infection Senegal

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rotator cuff tears: An evidence based approach

引用

World Journal of Orthopedics 2015年第11期6卷 902-918页

作者： Senthil Nathan Sambandam Vishesh Khanna Arif Gul Varatharaj Mounasamy Joint Reconstruction center Department of OrthopaedicsK.G. Hospital and Postgraduate Medical Institute DNB Orthopaedics Department of Ortho- paedicsK.G. Hospital and Postgraduate Medical Institute Princess Alexandra Hospital VCU Medical center ambulatory care center

Lesions of the rotator cuff(RC) are a common occurrence affecting millions of people across all parts of the globe. RC tears are also rampantly prevalent with an agedependent increase in numbers. Other associated factors include a history of trauma, limb dominance, contralateral shoulder, smoking-status, hypercholesterolemia, posture and occupational dispositions. The challenge lies in early diagnosis since a high proportion of patients are asymptomatic. Pain and decreasing shoulder power and function should alert the heedful practitioner in recognizing promptly the onset or aggravation of existing RC tears. Partial-thickness tears(PTT) can be bursalsided or articular-sided tears. Over the course of time, PTT enlarge and propagate into full-thickness tears(FTT) and develop distinct chronic pathological changes due to muscle retraction, fatty infiltration and muscle atrophy. These lead to a reduction in tendon elasticity and viability. Eventually, the glenohumeral joint experiences a series of degenerative alterations- cuff tear arthropathy. To avert this, a vigilant clinician must utilize and corroborate clinical skill and radiological findings to identify tear progression. Modern radio-diagnostic means of ultrasonography and magnetic resonance imaging provide excellent visualization of structural details and are crucial in determining further course of action for these patients. Physical therapy along with activity modifications, antiinflammatory and analgesic medications form the pillars of nonoperative treatment. Elderly patients with minimal functional demands can be managed conservatively and reassessed at frequent intervals. Regular monitoring helps in isolating patients who require surgical interventions. Early surgery should be considered in younger, active and symptomatic, healthy patients. In addition to being costeffective, this helps in providing a functional shoulder witha stable cuff. An easily reproducible technique of maximal strength and sturdiness

关键词： Rotator cuff tears Partial thickness tears Full thickness tear Natural history Ultrasonography Magnetic resonance imaging Single row repair Double row repair Healing

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Incidence and Factors Associated with the Switch to the Second Line Antiretroviral Treatment at the ambulatory Treatment center (CTA) in Dakar

引用

Health 2016年第14期8卷 1566-1575页

作者： Ndeye Fatou Ngom-Gueye Gilbert Batista Abdoul Aziz Ndiaye Assane Diouf KA. Daye Alioune Badara Tall Awa Diouf Kine Ndiaye Makhtar Ndiaga Diop Mountaga Dia Cheikh Tacko Diop Awa Gaye Cheikh Tidiane Ndour Moussa Seydi Lamine Gueye Bernard Marcel Diop Papa Salif Sow ambulatory Treatment center Fann University Teaching Hospital Dakar Senegal Department of Community Health Alioune Diop University Bambey Senegal Department of Infectious Diseases Fann University Teaching Hospital Dakar Senegal

Introduction: Over the past years, efforts have been made to expand access to antiretroviral combinations (cART) in low-income countries. However, major concerns are noted with drug resistance emergence, as treatment failure result and need to introduce a second line treatment, more expensive and difficult to implement. The objective was to study the incidence of switch to second line, reasons for switch and risk factors using a cohort of people living with HIV in an ambulatory Treatment center in Dakar. Methodology: This was a cohort study of people living with HIV under cART from January 2004 to December 2013. Naive patients monitored for at least six months, regardless of their profile and regimen with baseline CD4 counts Results: The median age of the 827 patients included was 44 [IQR = 18 - 78]. The switch to second-line treatment was observed in 72 patients (8.7%) after an average of 38.5 months of follow-up. The overall incidence rate of switch to second line of antiretroviral treatment was 1.59 per 100 persons-years. Most of changes in first-line treatment were motivated by virological failures (n = 60, 83.3%) under treatment with AZT/3TC/NVP (n = 25, 34.7%) or AZT/3TC/EFV21 (29.2%). 9.7% of switch occurred after immunological failure, 1.4% after clinical failure, 4.2% after severe toxicity and 1.4% was not documented. Predictive factors identifying failures at the end of the multivariate analysis were age Conclusions: In total, CTA identified a low incidence rate of treatment failure of the first line of treatment. Associated risk factors were age 3 and high viral load at treatment initiation.

关键词： Incidence Associated Factors Switch to 2nd Line cART CTA Dakar

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Efficacy and tolerability of a polysaccharide-resin-honey based cough syrup as compared to carbocysteine syrup for children with colds: a randomized, single-blinded,multicenter study

引用

World Journal of Pediatrics 2017年第1期13卷 27-33页

作者： Herman Avner Cohen Moshe Hoshen Shmuel Gur Arie Bahir Yoseph Laks Hannah Blau Pediatric ambulatory Community Clinic Petah—TikvaIsrael Sackler Faculty of Medicine Tel.Aviv UniversityTel—AvivIsrael Clalit Research Institute Chief Physician's OfficeClalit Health ServicesTel AvivIsrael Pediatric ambulatory Community Clinic Kefar SabaIsrael Pediatric ambulatory Community Clinic Bat YamIsrael Pediatric ambulatory Community Clinic Ramat Aviv.Israel Pulmonary Institute Schneider Children Medical Center ofIsrael.Petah Tikva.Israel.

Background:Available pediatric treatments for acute cough are limited by lack of demonstrated *** objective of this trial is to compare the effects of a poIysaccharide—resin-honey based cough syrup,and carbocysteine ... 详细信息

关键词： cough children upper respiratory tract infection

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hyperglycemia-induced myocardial fibrosis may be associated with pyroptosis and apoptosis of cardiomyoctes in diabetic mice

引用

BIOCELL 2023年第2期47卷 393-400页

作者： YAO LU QIUYUE WANG CAIHUI ZHANG Department of Anesthesiology The First Affiliated Hospital of Anhui Medical UniversityHefei230022China ambulatory Surgery center The First Affiliated Hospital of Anhui Medical UniversityHefei230022China

Myocardial fibrosis is an important manifestation of diabetic *** study investigated the potential mechanism of diabetic myocardial *** C57BL/6J and db/db mice aged 8 weeks were randomly divided into the diabetic(DB)and control *** 20 weeks,the mouse heart was harvested and subjected to hematoxylin-eosin staining(HE)and Masson staining to investigate the degree of *** expressions of transforming growth factor-beta 1(TGF-β1),collagen-III,B-cell lymphoma-2(Bcl2),Bcl2-associated X protein(Bax),cleaved gasdermin D(GSDMD),cysteinyl aspartate specific proteinase-1(caspase-1),apoptosis-associated speck-like protein containing a CARD(ASC),and nucleotide-binding oligomerization domain(NOD)-like receptor 3(NLRP3)were measured by western *** and TdT-mediated dUTP nick end labeling(TUNEL)staining were performed to analyze the development of apoptosis and pyroptosis.A significant increase in body weight and blood glucose in the DB group was *** pathological injury,fibrosis,apoptosis,and pyroptosis were more obvious and serious in the DB *** expression of anti-apoptotic Bcl2 significantly decreased,while the expression levels of pro-apoptotic Bax,caspase-3,and pyroptosis-related proteins,such as cleaved GSDMD,and caspase-1 in the DB group were significantly *** and apoptosis were probably the main mechanisms that caused myocardial fibrosis in mice with diabetes.

关键词： Pyroptosis Apoptosis Fibrosis Diabetes Diabetic cardiomyopathy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cancer metabolic reprogramming: importance, main features, and potentials for precise targeted anti-cancer therapies

引用

Cancer Biology & Medicine 2014年第1期11卷 1-19页

作者： Liem Minh Phan Sai-Ching Jim Yeung Mong-Hong Lee Department of Molecular and Cellular Oncology Department of General Internal Medicine Ambulatory Treatment and Emergency Care Department of Endocrine Neoplasia and Hormonal Disorders The University of Texas MD Anderson Cancer Center

Cancer cells are well documented to rewire their metabolism and energy production networks to support and enable rapid proliferation, continuous growth, survival in harsh conditions, invasion, metastasis, and resistance to cancer treatments. Since Dr. Otto Warhurg＇s discovery about altered cancer cell metabolism in 1930, thousands of studies have shed light on various aspects of cancer metabolism with a common goal to find new ways for effectively eliminating tumor cells by targeting their energy metabolism. This review highlights the importance of the main features of cancer metabolism, summarizes recent remarkable advances in this field, and points out the potentials to translate these scientific findings into life-saving diagnosis and therapies to help cancer patients.

关键词： Cell cycle energy metabolism glycolysis glutaminolysis mitochondria biogenesis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Potential applications of single-incision laparoscopic totally preperitoneal hernioplasty

引用

World Journal of Gastrointestinal Surgery 2024年第7期16卷 2202-2210页

作者： Xiao-Jun Wang Ting Fei Xiong-Hua Xiang Quan Wang En-Cheng Zhou Department of Gastrointestinal Surgery The First Affiliated Hospital of Ningbo UniversityNingbo 315020Zhejiang ProvinceChina ambulatory Surgery center Xijing HospitalAir Force Military Medical UniversityXi’an 710032Shaanxi ProvinceChina

BACKGROUND The totally preperitoneal(TPP)approach is a new concept that was recently *** the TPP approach combined with single-incision laparoscopic hernia repair has its own advantages,there is little evidence reflecting the characteristics and feasibility of either *** To analyze the potential applications of single-incision laparoscopic TPP(SILTPP)inguinal hernia hernioplasty for the treatment of inguinal *** A total of 152 SIL-TPP surgeries were performed at the First Affiliated Hospital of Ningbo University from February 2019 to November 2022.A single-port,named Iconport,and standard laparoscopic instruments were used during the *** data,intraoperative parameters and short-term postoperative outcomes were collected and retrospectively *** The demographic data of 152 patients underwent SIL-TPP were shown in Table *** average age was 49.5 years(range from 21 to 81 years).The average body mass index was 27.7 kg/m^(2)(range from 17.7 kg/m^(2) to 35.6 kg/m^(2)).SIL-TPP were conducted successfully in 147 *** patients were converted to the SILtransabdominal preperitoneal laparoscopic herniorrhaphy at the initial stage of the study due to a lack of *** 2 patients with incisional hernias,an auxiliary operation hole was added during the SIL-TPP procedure,as required for *** mean operative time was 64.5 minutes(range:36.0-110.0 minutes)for unilateral direct and femoral hernias and 81.6 minutes for indirect hernias(range:40.0-150.0 minutes).The mean postoperative hospital stay was 3.4 *** SIL-TPP is feasible and has advantages for inguinal hernia ***-TPP has potential benefits for patients with various abdominal wall ***,doctors should be encouraged to actively apply the TPP approach combined with a single incision in their daily work.

关键词： Totally preperitoneal hernioplasty Iconport Single incision laparoscopic Totally extraperitoneal herniorrhaphy Single incision laparoscopic totally preperitoneal hernioplasty

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The quality of escalator signage for public safety in Malaysia:an observational study

引用

Global Health Journal 2021年第4期5卷 198-203页

作者： Chii-Chii Chew Chee-Tao Chang Xin-Jie Lim Hasni-Adha Ibrahim Hamiazwa Azmi Nur-Ilyana Wahabi Nur-Shuhaida Hamdan Nurul-Atiqah Nazan Nur-Haliana Karim Nurfarahdila-Ahmad Malawi Ying-Ling Oon Norshazila-Julia MS Amar-Singh HSS Clinical Research center Hospital Raja Permaisuri BainunLevel 4Ambulatory Care CenterJalan Raja Ashman ShahIpohPerak 30450Malaysia Allied Health Science College Sultan Azlan Shah Ministry of HealthTanjong RambutanIpohPerak Darul Ridzuan 31250Malaysia Department of Paediatric Hospital Raja Permaisuri BainunMinistry of HealthJalan Raja Ashman ShahIpohPerak 30450Malaysia

Objective:Escalator signage could be playing a vital role to alert users for safe use of *** study aimed to evaluate the availability,standardization,and content of safety information on escalator signage in the shopping ***:An observational study was conducted from November 2017 to February 2018 to assess the availability,standardization of safety information among the signage inside the shopping mall,and the content of safety information for public safety in Malaysia.A checklist was developed by adapting escalator safety guidelines from seven countries and regions including *** collctors identified from the selected states were required to capture three photographs at different angles of the escalator signage for each ascending and descending directions at each entrance of the *** analysis was performed;each criterion was presented in frequency and ***:A total of 268 escalators from 84 shopping malls in 9 states of Malaysia were *** operating escalators were not equipped with *** than one-ifth(23.0%)of the signage was not standardized within the *** majority of safety information was displayed in the form of a pictogram,a minority of signage displayed information in both pictogram and text format:"children must hold hand"(12.7%)and"be careful of long clothing"(10.8%),***,"toddlers should be carried"(8.6%)and"take extra care with rubber shoes/tied shoes/laces"(30.2%)were found absent in most of the ***:Escalator signage was present in almost all of the escalators ***,non-standardization of the signage of escalators should warrant the attention of relevant authorities to revise the safety guideline s and improve the quality of escalator.

关键词： Elevators and escalators Safety Transportation facilities Environment and public health Malaysia

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：