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Deep Underground Science and Engineering 2024年第2期3卷 231-246页

作者： Xin Han Fei Ye Xingbo Han Chao Ren Jing Song Ruliang Zhao school of Highway Chang'an UniversityXi'anChina Shandong Province Transportation Planning and Design Institute JinanChina China Water Resources Beifang investigation Design and Research Co.Ltd.TianjinChina

To understand the mechanical response pattern of the existing structure and ground due to the construction of metro tunnels underneath,the finite difference method is adopted to study the torsional deformation and stress variation of the existing structure and the effect of underground carriageway structures on the surface subsidence.The curves of the maximum differential subsidence,torsion angle,and distortion of the cross-section of the existing structure show two peaks in succession during traversing of two metro tunnels beneath it.The torsion angle of the existing structure changes when the two tunnels traverse beneath it in opposite directions.The first traversing of the shield tunnel mainly induces the magnitude variation in torsional deformation of the existing structure,but the second traversing of the subsurface tunnel may cause a dynamic change in the magnitude and form of torsional deformation in the existing structure.The shielding effect can reduce the surface subsidence caused by metro tunnel excavation to a certain extent,and the development trend of subsidence becomes slower as the excavation continues.

关键词： metro tunnel numerical simulation structural deformation surface subsidence underground carriageway structure

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Development and validation of a nomogram to predict allograft survival after pediatric liver transplantation

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World Journal of Pediatrics 2024年第3期20卷 239-249页

作者： Guang-Xiang Gu Shu-Ting Pan Yi-Chen Fan Chen Chen Qiang Xia Department of Liver Surgery Renji HospitalShanghai Jiaotong University School of MedicineNo.160 Pujian RoadPudong New DistrictShanghai 200128China Department of Liver Transplantation Sun Yet-Sen Memorial HospitalSun Yat-Sen UniversityNo.107 Yanjiang West RoadGuangzhou 510080China Clinical Center for investigation Renji HospitalShanghai Jiaotong University School of MedicineShanghaiChina Department of Anesthesiology Renji HospitalShanghai Jiaotong University School of MedicineShanghaiChina

Background Liver transplantation is the main treatment for cholestatic liver disease and some metabolic liver diseases in children.However,no accurate prediction model to determine the survival probability of grafts prior to surgery exists.This study aimed to develop an effective prognostic model for allograft survival after pediatric liver transplantation.Methods This retrospective cohort study included 2032 patients who underwent pediatric liver transplantation between January 1,2006,and January 1,2020.A nomogram was developed using Cox regression and validated based on bootstrap sampling.Predictive and discriminatory accuracies were determined using the concordance index and visualized using calibration curves;net benefits were calculated for model comparison.An online Shiny application was developed for easy access to the model.Results Multivariable analysis demonstrated that preoperative diagnosis,recipient age,body weight,graft type,preoperative total bilirubin,interleukin-1β,portal venous blood flow direction,spleen thickness,and the presence of heart disease and cholangitis were independent factors for survival,all of which were selected in the nomogram.Calibration of the nomogram indicated that the 1-,3-,and 5-year predicted survival rates agreed with the actual survival rate.The concordance indices for graft survival at 1,3,and 5 years were 0.776,0.757,and 0.753,respectively,which were significantly higher than those of the Pediatric End-Stage Liver Disease and Child-Pugh scoring systems.The allograft dysfunction risk of a recipient could be easily predicted using the following URL:https://aspelt.***.io/ASPELT/l Conclusion The allograft survival after pediatric liver transplantation(ASPELT)score model can effectively predict the graft survival rate after liver transplantation in children,providing a simple and convenient evaluation method for clinicians and patients.

关键词： Allograft survival Nomogram Pediatric liver transplantation

Characterization of sand convective motions at a vertical wall subjected to long-term cyclic loading

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Fundamental Research 2024年第2期4卷 334-343页

作者： Dawei Guan Jialong Li Yee-Meng Chiew Jisheng Zhang Key Laboratory of Ministry of Education for Coastal Disaster and Protection Hohai UniversityNanjing 210024China College of Harbour Coastal and Offshore EngineeringHohai UniversityNanjing 210024China Shanghai investigation Design and Research Institute Co.LtdShanghai 200335China school of Civil and Environmental Engineering Nanyang Technological UniversitySingapore 639798Singapore

By conducting a two-dimensional experimental study,this paper aims to enhance the understanding of the mechanism of sand convective motions in the vicinity of a wall subjected to long-term cyclic lateral loadings.The experimental tests were conducted in a rectangular sandbox with a transparent front-wall,through which the process of sand particle motions could be recorded by using a high-resolution digital camera.The images were processed with a high time-resolved PIV(Particle Image Velocimetry)system.Based on the experimental data,this work(1)presents the sand flow field in the convective zones;(2)provides means to describe the convection mechanism;(3)proposes the relationships between the loading conditions and dimensions of the region with intense sand movement;and(4)elaborates the similarity of the sand flow velocity structure within the sand convective zones.

关键词： Vibration Soil/structure interaction Deformation Particle image velocimetry Laboratory tests

Major depressive disorder:hypothesis,mechanism,prevention and treatment

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Signal Transduction and Targeted Therapy 2024年第3期9卷 913-944页

作者： Lulu Cui Shu Li Siman Wang Xiafang Wu Yingyu Liu Weiyang Yu Yijun Wang Yong Tang Maosheng Xia Baoman Li Department of Forensic Analytical Toxicology School of Forensic MedicineChina Medical UniversityShenyangChina Liaoning Province Key Laboratory of Forensic Bioevidence Sciences ShenyangChina China Medical University Centre of Forensic investigation ShenyangChina International Joint Research Centre on Purinergic Signalling/Key Laboratory of Acupuncture for Senile Disease(Chengdu University of TCM) Ministry of Education/School of Health and RehabilitationChengdu University of Traditional Chinese Medicine/Acupuncture and Chronobiology Key Laboratory of Sichuan ProvinceChengduChina Department of Orthopaedics The First HospitalChina Medical UniversityShenyangChina

Worldwide,the incidence of major depressive disorder(MDD)is increasing annually,resulting in greater economic and social burdens.Moreover,the pathological mechanisms of MDD and the mechanisms underlying the effects of pharmacological treatments for MDD are complex and unclear,and additional diagnostic and therapeutic strategies for MDD still are needed.The currently widely accepted theories of MDD pathogenesis include the neurotransmitter and receptor hypothesis,hypothalamicpituitary-adrenal(HPA)axis hypothesis,cytokine hypothesis,neuroplasticity hypothesis and systemic influence hypothesis,but these hypothesis cannot completely explain the pathological mechanism of MDD.Even it is still hard to adopt only one hypothesis to completely reveal the pathogenesis of MDD,thus in recent years,great progress has been made in elucidating the roles of multiple organ interactions in the pathogenesis MDD and identifying novel therapeutic approaches and multitarget modulatory strategies,further revealing the disease features of MDD.Furthermore,some newly discovered potential pharmacological targets and newly studied antidepressants have attracted widespread attention,some reagents have even been approved for clinical treatment and some novel therapeutic methods such as phototherapy and acupuncture have been discovered to have effective improvement for the depressive symptoms.In this work,we comprehensively summarize the latest research on the pathogenesis and diagnosis of MDD,preventive approaches and therapeutic medicines,as well as the related clinical trials.

关键词： prevention acupuncture hypothesis

Multimodal Biometric Fusion Algorithm Based on Ranking Partition Collision Theory

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Machine Intelligence Research 2023年第6期20卷 884-896页

作者： Zhuorong Li Yunqi Tang school of criminal investigation People’s Public Security University of ChinaBeijing100038China

Score-based multimodal biometric fusion has been shown to be successful in addressing the problem of unimodal techniques’vulnerability to attack and poor performance in low-quality data.However,difficulties still exist in how to unify the meaning of heterogeneous scores more effectively.Aside from the matching scores themselves,the importance of the ranking information they include has been undervalued in previous studies.This study concentrates on matching scores and their ranking information and suggests the ranking partition collision(RPC)theory from the standpoint of the worth of scores.To meet both forensic and judicial needs,this paper proposes a method that employs a neural network to fuse biometrics at the score level.In addition,this paper constructs a virtual homologous dataset and conducts experiments on it.Experimental results demonstrate that the proposed method achieves an accuracy of 100%in both mAP and Rank1.To show the efficiency of the proposed method in practical applications,this work carries out more experiments utilizing real-world data.The results show that the proposed approach maintains a Rank1 accuracy of 99.2%on the million-scale database.It offers a novel approach to fusion at the score level.

关键词： Image processing convolutional neural network multimodal biometrics fusion

Regenerative medicine strategies for chronic complete spinal cord injury

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Neural Regeneration Research 2024年第4期19卷 818-824页

作者： Shogo Hashimoto Narihito Nagoshi Masaya Nakamura Hideyuki Okano Department of Orthopedic Surgery Keio University School of Medicine Department of Physiology Keio University School of Medicine

Spinal cord injury is a condition in which the parenchyma of the spinal cord is damaged by trauma or various diseases.While rapid progress has been made in regenerative medicine for spinal cord injury that was previously untreatable,most research in this field has focused on the early phase of incomplete injury.However,the majority of patients have chronic severe injuries;therefore,treatments for these situations are of fundamental importance.The reason why the treatment of complete spinal cord injury has not been studied is that,unlike in the early stage of incomplete spinal cord injury,there are various inhibitors of neural regeneration.Thus,we assumed that it is difficult to address all conditions with a single treatment in chronic complete spinal cord injury and that a combination of several treatments is essential to target severe pathologies.First,we established a combination therapy of cell transplantation and drug-releasing scaffolds,which contributes to functional recovery after chronic complete transection spinal cord injury,but we found that functional recovery was limited and still needs further investigation.Here,for the further development of the treatment of chronic complete spinal cord injury,we review the necessary approaches to the different pathologies based on our findings and the many studies that have been accumulated to date and discuss,with reference to the literature,which combination of treatments is most effective in achieving functional recovery.

关键词： cell transplantation chronic phase complete transection regenerative medicine spinal cord injury

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Whyand how tousethe SeqCode

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mLife 2024年第1期3卷 1-13页

作者： Wiliam B.Whitman Maria Chuvochina Brian P.Hedlund Konstantinos T.Konstantinidis Marike Palmer Luis M.Rodriguez-R lain Sutcliffe Fengping Wang Deparment of Microbioogy University of GeorgiaAthensGeorgiaUAA schoolof Chemistry and Molecular Biosciences Australian CentreforEogenomicsThe Universty of QueenslandSt LuciaAustralia University of Nevada Las Vegas Las VegasNevadaUSA Schol of Civil and Environmental Engineering and School of Biological SciencesGeorgia Institute of TechnologyAtlantaGeorgiaUSA Department of Microbiology University of ManitobaWinnipegManitobaCanada school of Life Sciences University of Nevada Las VegasLas VegasNevadaUSA Department of Microbiology and Digital Science Center(DiSC) University of InnsbruckInnsbruckAustria Faculty of Health&Life Sciences Northumbria UniversityNewcastle upon TyneUK school of Oceanography International Center for Deep Life InvestigationShanghai Jiao Tong UniversityShanghaiChina

The SeqCode,formally called the Code of Nomenclature of Prokaryotes Described from Sequence Data,is a new code of nomenclature in which genome sequences are the nomenclatural types for the names of prokaryotic species.While similar to the International Code of Nomenclature of Prokaryotes(ICNP)in structure and rules of priority,it does not require the deposition of type strains in international culture collections.Thus,it allows for the formation of permanent names for uncultured prokaryotes whose nearly complete genome sequences have been obtained directly from environmental DNA as well as other prokaryotes that cannot be deposited in culture collections.Because the diversity of uncultured prokaryotes greatly exceeds that of readily culturable prokaryotes,the SeqCode is the only code suitable for naming the majority of prokaryotic species.The start date of the SeqCode was January 1,2022,and the online Registry(https://seqco.del)was created to ensure valid publication of names.The SeqCode recognizes all names validly published under the ICNP before 2022.After that date,names validly published under the SeqCode compete with ICNP names for priority.As a result,species can have only one name,either from the SeqCode or ICNP,enabling effective communication and the creation of unified taxonomies of uncultured and cultured prokaryotes.The SeqCode is administered by the SeqCode Committee,which is comprised of the SeqCode Community and elected administrative components.Anyone with an interest in the systematics of prokaryotes is encouraged to join the SeqCode Community and participate in the development of this resource.

关键词： genome sequences metagenome-assembled genomes nomenclature SeqCode

Geochronology,Geochemistry,and Sr-Nd-Hf Isotopes of the Diorite Porphyrites from the Weining Beishan Area,Ningxia Hui Autonomous Region:Constraints on Their Source and Tectonic Implications

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Journal of Earth Science 2024年第2期35卷 462-475页

作者： Anlu Liu Lianfu Hai Jinke Liu Xiaojun Zhang Haifeng Li Fengshun Zhao Guoliang Zhao Jinhe Bai Yifu Museum China University of GeosciencesWuhan430074China school of Earth Resources China University of GeosciencesWuhan430074China Mineral Geological Survey Institute of Ningxia Hui Autonomous Region Yinchuan750021China National Demonstration Center for Experimental Mineral Exploration Education China University of GeosciencesWuhan430074China Coal Geological Survey Institute of Ningxia Hui Autonomous Region Yinchuan750021China Zhuhai Engineering investigation Institute of Guangdong Province Zhuhai519000China

The Weining Beishan area of Ningxia Hui Autonomous Region is located at on the western edge of the Helanshan tectonic belt,which is a tectonic joint among Alxa Block,Ordos Block,and North Qilian orogenic belt.However,the tectonic evolution of this area remains unclear due to the lack of magmatic information.This paper conducted researches on geochronology,geochemistry,and Sr-Nd-Hf isotopes of the diorite porphyrites exposed in the Weining Beishan area.The zircon U-Pb dating yields two ages of 145.0±1.1 and 146.2±1.5 Ma,and the whole-rock geochemical data indicate that the diorite porphyrites are metaluminous to weakly peraluminous and high-K calc-alkaline series.The characteristics of highly initial^(87)Sr/^(86)Sr ratios(0.70816 to 0.71047),negativeε_(Nd)(t)(−8.9 to−8.4),and negativeε_(Hf)(t)(−13.8 to−21.2)indicate that the diorite porphyrites originated from partial melting of the middle-lower ancient crust related to the North China Craton.Combined with the regional geology,we suggested that partial melting was triggered by a tectonic activity of deep faults cutting through the crust under the regional stress transformation from compressing to extension during the Late Jurassic–Early Cretaceous,which is probably related to the westward subduction of the Paleo-Pacific Plate.

关键词： zircon U-Pb dating Sr-Nd-Hf isotopes magma source diorite porphyrite Weining Beishan area Ningxia Hui Autonomous Region geochronology geochemistry

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Frictional contact analysis of a rigid solid with periodic surface sliding on the thermoelectric material

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Applied Mathematics and Mechanics(English Edition) 2024年第1期45卷 179-196页

作者： Yali ZHANG Yueting ZHOU Shenghu DING school of Mathematics and Statistics Ningxia UniversityYinchuan 750021China school of Aerospace Engineering and Applied Mechanics Tongji UniversityShanghai 200092China

Understanding and characterizing rough contact and wavy surfaces are essential for developing effective strategies to mitigate wear,optimize lubrication,and enhance the overall performance and durability of mechanical systems.The sliding friction contact problem between a thermoelectric(TE)half-plane and a rigid solid with a periodic wavy surface is the focus of this investigation.To simplify the problem,we utilize mixed boundary conditions,leading to a set of singular integral equations(SIEs)with the Hilbert kernels.The analytical solutions for the energy flux and electric current density are obtained by the variable transform method in the context of the electric and temperature field.The contact problem for the elastic field is transformed into the second-kind SIE and solved by the Jacobi polynomials.Notably,the smoothness of the wavy contact surface ensures that there are no singularities in the surface contact stress,and ensures that it remains free at the contact edge.Based on the plane strain theory of elasticity,the analysis primarily examines the correlation between the applied load and the effective contact area.The distribution of the normal stress on the surface with or without TE loads is discussed in detail for various friction coefficients.Furthermore,the obtained results indicate that the in-plane stress decreases behind the trailing edge,while it increases ahead of the trailing edge when subjected to TE loads.

关键词： wavy surface periodic contact thermoelectric(TE)material Hilbert integral kernel

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Attention-Based CNN Fusion Model for Emotion Recognition During Walking Using Discrete Wavelet Transform on EEG and Inertial Signals

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Big Data Mining and Analytics 2024年第1期7卷 188-204页

作者： Yan Zhao Ming Guo Xiangyong Chen Jianqiang Sun Jianlong Qiu school of Communication Engineering Hangzhou Dianzi UniversityHangzhou 310018China school of Automation and Electrical Engineering Linyi UniversityLinyi 276000China

Walking as a unique biometric tool conveys important information for emotion recognition.Individuals in different emotional states exhibit distinct walking patterns.For this purpose,this paper proposes a novel approach to recognizing emotion during walking using electroencephalogram(EEG)and inertial signals.Accurate recognition of emotion is achieved by training in an end-to-end deep learning fashion and taking into account multi-modal fusion.Subjects wear virtual reality head-mounted display(VR-HMD)equipment to immerse in strong emotions during walking.VR environment shows excellent imitation and experience ability,which plays an important role in awakening and changing emotions.In addition,the multi-modal signals acquired from EEG and inertial sensors are separately represented as virtual emotion images by discrete wavelet transform(DWT).These serve as input to the attention-based convolutional neural network(CNN)fusion model.The designed network structure is simple and lightweight while integrating the channel attention mechanism to extract and enhance features.To effectively improve the performance of the recognition system,the proposed decision fusion algorithm combines Critic method and majority voting strategy to determine the weight values that affect the final decision results.An investigation is made on the effect of diverse mother wavelet types and wavelet decomposition levels on model performance which indicates that the 2.2-order reverse biorthogonal(rbio2.2)wavelet with two-level decomposition has the best recognition performance.Comparative experiment results show that the proposed method outperforms other existing state-of-the-art works with an accuracy of 98.73%.

关键词： walking multi-modal fusion virtual reality emotion recognition discrete wavelet transform attention mechanism