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Comprehending drivers of land use land cover change from 1999 to 2021 in the Pithoragarh District,Kumaon Himalaya,Uttarakhand,India

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Journal of Mountain Science 2024年第7期21卷 2394-2407页

作者： Mahika PHARTIYAL Sanjeev SHARMA centre for the Study of regional Development Jawaharlal Nehru UniversityNew Delhi 110067India

The Himalayan region has been experiencing stark impacts of climate change,demographic and livelihood pattern *** analysis of land use and land cover(LULC)change provides insights into the shifts in spatial and temporal patterns of *** changes are the combined effects of anthropogenic and natural/climatic *** present study attempts to monitor and comprehend the main drivers behind LULC changes(1999-2021)in the Himalayan region of Pithoragarh district,*** district is a border district,remotely located in the north-east region of Uttarakhand,*** study draws upon primary and secondary data sources.A total of 400 household surveys and five group discussions from 38 villages were conducted randomly to understand the climate perception of the local community and the drivers of *** imagery,CRU(Climatic Research Unit)climate data and climate perception data from the field have been used to comprehensively comprehend,analyze,and discuss the trends and reasons for LULC *** and remote sensing techniques were used to construct LULC *** multifaceted approach ensures comprehensive and corroborated *** classes were identified and formed viz-cultivation,barren,settlement,snow,and *** show that vegetation and builtup have increased whereas cultivation,barren land,and snow cover have *** study further aims to elucidate the causes behind LULC changes in the spatially heterogeneous region,distinguishing between those attributed to human activities,climate shifts,and the interconnected impacts of *** study provides a comprehensive picture of the study area and delivers a targeted understanding of local drivers and their potential remedies by offering a foundation for formulating sustainable adaptation policies in the region.

关键词： Himalayan region Land use/land cover change Anthropogenic factors Climate change Socioecological system

GeMemiOM: the curated database on genes, putative methylation study targets, and microRNA targets for otitis media

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Journal of Genetics and Genomics 2024年第2期51卷 260-263页

作者： Kondyarpu Abhishek Bineet Kumar Mohanta Pratima Kumari Anshuman Dixit Puppala Venkat Ramchander Institute of Life Sciences Nalco SquareChandrasekharpurBhubaneswarIndia regional Center for biotechnology FaridabadHaryanaIndia

Otitis media(OM),the most underrated middle ear disease,often onsets during childhood and gets complicated in susceptible *** of the middle ear(ME)leads to its degradation and abnormal physiological *** ME inflammation sometimes results in lethal secondary complications(Penido et al.,2016).OM is a corroboration of multiple facets that leads to disabling hearing loss and associated *** of the facets constituted are genetic,epigenetic,immunogenetic,anatomical.

关键词： inflammation media

Constructing a biofunctionalized 3D-printed gelatin/sodium alginate/chitosan tri-polymer complex scaffold with improvised biological andmechanical properties for bone-tissue engineering

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Bio-Design and Manufacturing 2024年第1期7卷 57-73页

作者： Amit Kumar Singh Krishna Pramanik Amit Biswas centre of Excellence in Tissue Engineering Department of Biotechnology and Medical EngineeringNational Institute of TechnologyRourkela 769008India

Sodium alginate(SA)/chitosan(CH)polyelectrolyte scaffold is a suitable substrate for tissue-engineering *** present study deals with further improvement in the tensile strength and biological properties of this type of scaffold to make it a potential template for bone-tissue *** experimented with adding 0%–15%(volume fraction)gelatin(GE),a protein-based biopolymer known to promote cell adhesion,proliferation,and *** resulting tri-polymer complex was used as bioink to fabricate SA/CH/GEmatrices by three-dimensional(3D)*** studies using scanning electron microscopy revealed the microfibrous porous architecture of all the structures,which had a pore size range of 383–419μm.X-ray diffraction and Fourier-transform infrared spectroscopy analyses revealed the amorphous nature of the scaffold and the strong electrostatic interactions among the functional groups of the polymers,thereby forming polyelectrolyte complexes which were found to improve mechanical properties and structural *** scaffolds exhibited a desirable degradation rate,controlled swelling,and hydrophilic characteristics which are favorable for bone-tissue *** tensile strength improved from(386±15)to(693±15)kPa due to the increased stiffness of SA/CH scaffolds upon addition of *** enhanced protein adsorption and in vitro bioactivity(forming an apatite layer)confirmed the ability of the SA/CH/GE scaffold to offer higher cellular adhesion and a bone-like environment to cells during the process of tissue *** vitro biological evaluation including the MTT assay,confocal microscopy analysis,and alizarin red S assay showed a significant increase in cell attachment,cell viability,and cell proliferation,which further improved biomineralization over the scaffold *** addition,SA/CH containing 15%gelatin designated as SA/CH/GE15 showed superior performance to the other fabricated 3D structures,demonstrating its pote

关键词： Scaffold Biomaterial Sodium alginate Chitosan Gelatin 3D printing Tissue engineering

A Review on Characteristics, Extraction Methods and Applications of Renewable Insect Protein

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Journal of Renewable Materials 2024年第5期12卷 923-950页

作者： Adelya Khayrova Sergey Lopatin Valery Varlamov Research centre of biotechnology of the Russian Academy of Sciences Moscow119071Russia

Due to the expected rise in the world population,an increase in the requirements for quality and safety of food and feed is expected,which leads to the growing demand for new sources of sustainable and renewable *** protein is gaining importance as a renewable material for several reasons,reﬂecting its potential contribu-tions to sustainability,resource efﬁciency,and environmental *** insect species are known to be able to efﬁciently convert organic waste into high-value products such as protein,requiring less land and water compared to traditional *** addition,insect farming produces fewer greenhouse gas emissions,contri-buting to mitigating climate *** are considered as a major potential alternative to animal or plant protein due to their many nutritional beneﬁts,including high protein,mineral,and vitamin *** average,the protein content of insects ranges between 35%and 60%dry weight,which exceeds plant protein sources,such as cereal,soybeans,and *** the acceptance of insect protein grows and technologies advance,the food and feed industries continue to explore and expand their applications,offering consumers diverse and sustainable pro-tein *** this review,we discuss the recentﬁndings relating to insect protein focusing on its characteristics,extraction methods,applications,and opportunities along with some trade-offs and uncertainties.

关键词： Circular economy waste utilisation protein insect Hermetia illucens

Transcriptomic and pathological profiling of a new congenic mouse model with Lepr mutation:Evaluating susceptibility to the development of obesity and NAFLD

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Genes & Diseases 2024年第3期11卷 34-38页

作者： MJ Mahesh Kumar Shailendra Arindkar Masum Saini Perumal Nagarajan National Institute of Immunology New Delhi 100067India Center for Cellular and Molecular Biology Hyderabad 500007India regional Center for biotechnology Faridabad 121001India

Non-alcoholic fatty liver disease(NAFLD)and type 2 diabetes mellitus(T2DM)are two disease conditions for which obesity is a risk factor.^(1)Due to the close relationship between the three pathologies,researchers frequently use the same mouse models to identify the underlying processes of obesity,NAFLD,and *** instance,leptin(Lep)-null(ob/ob)and leptin receptor(Lepr)-deficient(db/db)mice spontaneously develop NAFLD and show different phenotypes of extreme obesity and diabetes,respectively.

关键词： obesity NAFLD Lep

Investigation of the effect of hydrocarbons and monoesters in the gelators’composition on the properties of edible oleogel

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Grain & Oil Science and Technology 2024年第2期7卷 96-104页

作者： Yuliya Frolova Roman Sobolev Varuzhan Sarkisyan Alla Kochetkova Federal Research centre of Nutrition Biotechnology and Food Safety2/14 Ustyinsky ProyezdMoscow 109240Russia

Natural wax gelators have different compositions of compounds(hydrocarbons,wax esters,free fatty alcohols,and free fatty acids),which results in oleogels with varying *** maintain a consistent composition,the individual components can be added to the original wax *** content of hydrocarbons and wax esters greatly affects the structuring process of liquid edible oils with *** aim of this study was to evaluate the possibility of modifying the properties of beeswax as a gelling agent by adding hydrocarbons or monoesters to obtain oleogels with specific *** tests were conducted to assess the changes in the oleogel properties,such as color,microstructure,oil-binding capacity,thermal and textural *** research results have shown that the addition of the studied fractions has led to a significant change in all properties of *** initial size of oleogel crystals(7.29±1.80μm)changed after adding fractions,varying from 5.28μm to 12.58μm with hydrocarbons and from 9.95μm to 30.41μm with wax *** addition of 30%–50% hydrocarbons decreased the ability of the oleogels to bind oil and made them less firm compared to samples with 10%-20% *** 10%-20% monoesters increased the firmness of the oleogels,but this indicator decreased when their content was increased to 50%.The obtained data indicate that hydrocarbons and wax esters can be used for targeted correction of the gelling properties of beeswax.

关键词： Oleogel Beeswax Hydrocarbons Wax monoesters Component composition of gelator Textural properties Food

Performance validation of High Mountain Asia 8-meter Digital Elevation Model using ICESat-2 geolocated photons

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Journal of Mountain Science 2024年第8期21卷 2562-2578页

作者： Giribabu DANDABATHULA Subham ROY Omkar Shashikant GHATAGE Vaibhav Balaso KOLASE Shwetambari SATPUTE Koushik GHOSH Sahibnoor KAUR Satyanarayana PONDARI Apurba Kumar BERA Sushil Kumar SRIVASTAV regional Remote Sensing centre-West National Remote Sensing CentreIndian Space Research OrganisationJodhpur 342005India Department of Geography School of Earth SciencesBharathidasan UniversityTiruchirappalli 620024India centre for Climate Change and Water Research Suresh Gyan Vihar UniversityJaipur 302017India Department of Geography Panjab UniversityChandigarh 160014India National Remote Sensing centre Indian Space Research OrganisationHyderabad 500037India regional centres National Remote Sensing CentreIndian Space Research OrganisationNew Delhi 110049India

High Mountain Asia(HMA),recognized as a third pole,needs regular and intense studies as it is susceptible to climate *** accurate and high-resolution Digital Elevation Model(DEM)for this region enables us to analyze it in a 3D environment and understand its intricate role as the Water Tower of *** science teams of NASA realized an 8-m DEM using satellite stereo imagery for HMA,termed HMA 8-m *** this research,we assessed the vertical accuracy of HMA 8-m DEM using reference elevations from ICESat-2 geolocated photons at three test sites of varied topography and land *** were made from statistical quantifiers and elevation *** the world’s highest mountain,Mount Everest,and its surroundings,Root Mean Squared Error(RMSE)and Mean Absolute Error(MAE)resulted in 1.94 m and 1.66 m,respectively;however,a uniform positive bias observed in the elevation profiles indicates the seasonal snow cover change will dent the accurate estimation of the elevation in this sort of test *** second test site containing gentle slopes with forest patches has exhibited the Digital Surface Model(DSM)features with RMSE and MAE of 0.58 m and 0.52 m,*** third test site,situated in the Zanda County of the Qinghai-Tibet,is a relatively flat terrain bed,mostly bare earth with sudden river cuts,and has minimal errors with RMSE and MAE of 0.32 m and 0.29 m,respectively,and with a negligible ***,in one more test site,the feasibility of detecting the glacial lakes was tested,which resulted in exhibiting a flat surface over the surface of the lakes,indicating the potential of HMA 8-m DEM for deriving the hydrological *** results accrued in this investigation confirm that the HMA 8-m DEM has the best vertical accuracy and should be of high use for analyzing natural hazards and monitoring glacier surfaces.

关键词： High Mountain Asia Digital Elevation Model ICESat-2 geolocated photons Accuracy assessment

Quaternionic Monge–Ampère Measure on Pluripolar Set

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Acta Mathematica Sinica,English Series 2024年第6期40卷 1431-1457页

作者： Hichame AMAL Saïd ASSERDA Fadoua BOUKHARI Department of Mathematics Laboratory LaREAMIRegional Centre of Trades of Education and TrainingKenitraMorocco Ibn Tofail University Faculty of SciencesDepartment of MathematicsPO 242 KenitraMorroco

In this paper, we prove that in a hyperconvex domain Ω in H^(n), if a non-negative Borel measure is dominated by a quaternionic Monge–Ampère measure, then it is a quaternionic Monge–Ampère measure of a function i... 详细信息

关键词： Quaternion space Monge-Amp`ere operator plurisubharmonic function

Drosophila X virus-like particles as delivery carriers for improved oral insecticidal efficacy of scorpion Androctonus australis peptide against the invasive fruit fly,Drosophila suzukii

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Insect Science 2024年第3期31卷 847-858页

作者： Qi Xue Luc Swevers Clauvis Nji Tizi Taning Faculty of Bioscience Engineering Department of Plants and CropsGhent UniversityGhentBelgium Insect Molecular Genetics and biotechnology Institute of Biosciences and ApplicationsNational Centre for Scientific Research"Demokritos"AthensGreece

Insect-specific neurotoxic peptides derived from the venoms of scorpions and spiders can cause acute paralysis and death when injected into insects,offering a promising insecticidal component for insect pest ***,effective delivery systems are required to help neurotoxic peptides pass through the gut barrier into the hemolymph,where they can ***,we investigated the potential of a novel nanocarrier,Drosophila X virus-like particle(DXV-VLP),for delivering a neurotoxin from the scorpion Androctonus australis Hector(AaIT)against the invasive pest fruit fly,Drosophila *** results show that the fusion proteins of DXV polyproteins with AalT peptide at their Ctermini could be sufficiently produced in Lepidoptera Hi5 cells in a soluble form using the recombinant baculovirus expression system,and could self-assemble into VLPs with similar particle morphology and size to authentic DXV *** addition,the AalT peptides displayed on DXV-VLPs retained their toxicity,as demonstrated in injection bioassays that resulted in severe mortality(72%)in adults after 72 *** fed to adults,mild mortality was observed in the group treated with DXV-AalT(38%),while no mortality occurred in the group treated with AaIT peptide,thus indicating the significant role of DXV-VLPs in delivering AalT ***,this proof-of-concept study demonstrates for the first time that VLPs can be exploited to enhance oral delivery of insect-specific neurotoxic peptides in the context of pest ***,it provides insights for further improvements and potentially the development of neurotoxin-based bioinsecticides and/or transgenic crops for insect pest control.

关键词： AalT Drosophila suzuki nanocarrier neurotoxic peptides pest control virus-like particle(VLP)