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Advances in haemostatic sponges: Characteristics and the underlying mechanisms for rapid haemostasis

Bioactive Materials 2023年第9期27卷 231-256页

作者： Akriti Nepal Huong D.N.Tran Nam-Trung Nguyen Hang Thu Ta queensland Micro-and nanotechnology centre Griffith UniversityNathanQueensland4111Australia Australian Institute for Bioengineering and nanotechnology University of QueenslandSt LuciaQueensland4072Australia Bioscience Discipline School of Environment and ScienceGriffith UniversityNathanQueensland4111Australia

In traumatized patients, the primary cause of mortality is uncontrollable continuous bleeding and unexpected intraoperative bleeding which is likely to increase the risk of complications and surgical failure. High expansion sponges are effective clinical practice for the treatment of wound bleeding (irregular/deep/narrow) that are caused by capillaries, veins and even arterioles as they possess a high liquid absorption ratio so can absorb blood platelets easily in comparison with traditional haemostasis treatments, which involve compression, ligation, or electrical coagulation etc. When in contact with blood, haemostatic sponges can cause platelet adhesion, aggregation, and thrombosis, preventing blood from flowing out from wounds, triggering the release of coagulation factors, causing the blood to form a stable polymerized fibre protein, forming blood clots, and achieving the goal of wound bleeding control. Haemostatic sponges are found in a variety of shapes and sizes. The aim of this review is to facilitate an overview of recent research around haemostatic sponge materials, products, and technology. This paper reviews the synthesis, properties, and characteristics of haemostatic sponges, together with the haemostasis mechanisms of haemostatic sponges (composite materials), such as chitosan, cellulose, gelatin, starch, graphene oxide, hyaluronic acid, alginate, polyethylene glycol, silk fibroin, synthetic polymers silver nanoparticles, zinc oxide nanoparticles, mesoporous silica nanoparticles, and silica nanoparticles. Also, this paper reviews commercial sponges and their properties. In addition to this, we discuss various in-vitro/in-vivo approaches for the evaluation of the effect of sponges on haemostasis .

关键词： Haemostatic sponge Characteristics Mechanism Haemostasis Nanoparticles

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Perovskite solar modules hit new efficiency record

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Science Bulletin 2017年第19期62卷 1293-1294页

作者： Yang Bai Lianzhou Wang Nanomaterials centre Australian Institute for Bioengineering and Nanotechnology and School of Chemical EngineeringThe University of Queensland

The last few years witnessed exceptional advancement of organohalide perovskite photovoltaics owing to their intriguing optoelectronic *** power conversion efficiency(PCE)of the state-of-art lab-scale perovskite solar... 详细信息

关键词：太阳能电池钙钛矿组件功率转换效率实验室规模光电特性 PSCs 孔面积

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Noble-metal-free MoS2/Ta3N5 heterostructure photocatalyst for hydrogen generation

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Progress in Natural Science:Materials International 2018年第2期28卷 189-193页

作者： Mu Xiao Bin Luo Supphasin Thaweesak Lianzhou Wang Nanomaterials centre School of Chemical Engineering and Australian Institute for Bioengineering and Nanotechnology the University of Queensland

A noble-metal-free heterostructure composed of Ta3N5nanosheets and MoS2co-catalyst was developed as an efficient photocatalyst for hydrogen production. In special, the MoS2/Ta3N5heterostructure with 5.2 wt% of MoS2exhibits a H2generation rate of 119.4 μmol h-1g-1, which is comparable to that of Ta3N5nanosheets with Pt as co-catalyst. The efficient H2 generation for MoS2/Ta3N5 heterostructure is resulted from the short diffusion distance of photo-excited charge carriers in Ta3 N5 nanosheets, efficient transfer of electrons from Ta3 N5 nanosheets to MoS2surface, and reduced overpotential for water reduction. Furthermore, the stability of the MoS2/Ta3N5heterostructured photocatalysts are evaluated for the photocatalytic H2generation.

关键词： MoS2 Ta3N5 nanosheets Heterostructure Photocatalysis Hydrogen evolution

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Ternary solvent boosts two-dimensional perovskites

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Science Bulletin 2017年第7期62卷 462-463页

作者： Miaoqiang Lyu Lianzhou Wang Nanomaterials centre School of Chemical Engineering and Australian Institute for Bioengineering and NanotechnologyThe University of Queensland

In the past few years,organic–inorganic/inorganic lead halide perovskites,most notably CH3NH3Pb I3and its mixed cation/anion compounds,have attracted tremendous research interests in a wide range of different disciplines,which is largely initialized by their unprecedented success in low-cost and highly efficient solar *** certified efficiencies of over 22%in the lab-scale devices,

关键词： Pb Ternary solvent boosts two-dimensional perovskites NH

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DNA-directed assembly of copper nanoblocks with inbuilt fluorescent and electrochemical properties： Application in simultaneous amplification-free analysis of multiple RNA species

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Nano Research 2018年第2期11卷 940-952页

作者： Kevin M. Koo Laura G. Carrascosa Matt Trau centre for Personalized Nanomedicine Australian Institute for Bioengineering and Nanotechnology (AIBN) The University of Queensland Brisbane Australia School of Chemistry and Molecular Biosciences The University of queensland Brisbane Australia

The intrinsic affinity of DNA molecules toward metallic ions can drive the specific formation of copper nanostructures within the nucleic acid helix structure in a sequence-dependent manner. The resultant nanostructures have interesting fluorescent and electrochemical properties, which are attractive for novel biosensing applications. However, the potential of using DNA-templated nano- structures for precision disease diagnosis remains unexplored. Particularly, DNA- templated nanostructures show high potential for the universal amplification-free detection of different RNA biomarker species. Because of their low cellular levels and differing species-dependent length and sequence features, simultaneous detection of different messenger RNAs, microRNAs, and long non-coding RNAs species with a single technique is challenging. Here, we report a contemporary technique for facile in situ assembly of DNA-templated copper nanoblocks （CuNBs） on various RNA species targets after hybridization-based magnetic isolation. Our approach circumvents the typical limitations associated with amplification and labeling procedures of current RNA assays. The synthesized CuNBs enabled amplification-free fM-level RNA detection with flexible fluorescence or electrochemical readouts. Furthermore, our nanosensing technique displays potential for clinical application, as demonstrated by non-invasive analysis of three diagnostic RNA biomarkers from a cohort of 10 prostate cancer patient urinary samples with 100%-concordance （quantitative reverse transcription- polymerase chain reaction （PCR） validation）. The good analytical performance and versatility of our method may be useful in both diagnostics and research fields.

关键词： prostate cancer RNA detection DNA-templated coppernanostTuctures amplification-free fluorescence detection electrochemical detection

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Recent Progress on Visible Light Responsive Heterojunctions for Photocatalytic Applications

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Journal of Materials Science & Technology 2017年第1期33卷 1-22页

作者： Songcan Wang Jung-Ho Yun Bin Luo Teera Butburee Piangjai Peerakiatkhajohn Supphasin Thaweesak Mu Xiao Lianzhou Wang Nanomaterials centre School of Chemical EngineeringAustralian Institute for Bioengineering and NanotechnologyThe University of QueenslandBrisbaneQLD 4072Australia

Photocatalysis has attracted much attention in recent years due to its potential in solving energy and environmental issues. Even though numerous achievements have been made, the photocatalytic systems developed to date are still far from practical applications due to the low efficiency and poor durability. Efficient light absorption and charge separation are two of the key factors for the exploration of high performance photocatalytic systems, which is generally difficult to be obtained in a single photocata- lyst. The combination of various materials to form heterojunctions provides an effective way to better harvest solar energy and to facilitate charge separation and transfer, thus enhancing the photocatalytic activity and stability. This review concisely summarizes the recent development of visible light respon- sive heterojunctions, including the preparation and performances of semiconductor/semiconductor junctions, semiconductor/cocatalyst junctions, semiconductor/metal junctions, semiconductor/non- metal junctions, and surface heterojunctions, and their mechanism for enhanced light harvesting and charge separation/transfer.

关键词： Heterojunction Photocatalysis Water splitting Carbon dioxide reduction Organic pollutant degradation Visible light

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Converting natural gas:quantum-sized bismuth vanadate holds the key for selective photocatalytic oxidation of methane

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Science China Chemistry 2021年第5期64卷 686-687页

作者： Lianzhou Wang Nanomaterials centre School of Chemical Engineering and Australian Institute for Bioengineering and NanotechnologyThe University of QueenslandSt LucaQueensland 4072Australia

Methane(CH_(4))is the main component of natural gas,causing severe greenhouse effect[1].To date,about 90%of CH_(4)is burned into carbon dioxide(CO_(2))and released into the atmosphere through various ways,resulting in not only a waste of resource but also a damage to the environment[2].Seeking efficient ways to convert CH_(4)into valuable fuels and chemicals is highly appealing for the rational use of fossil fuels and renewable energy feedstock,as well as for reducing greenhouse gas *** CH_(4)oxidation represents a promising greener approach that utilizes abundant sunlight to produce liquid fuels under mild conditions compared with the traditional thermocatalytic conversion of CH_(4)process.

关键词： process. holds sized

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Nano-confined ammonia borane for chemical hydrogen storage

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Frontiers of Chemical Science and Engineering 2012年第1期6卷 27-33页

作者： M. A.WAHAB Huijun ZHAO X. D. YAO ARC centre of Excellence for Functional Nanomaterials Australian Institute for Engineering and Nanotechnology the University of Queensland St Lucia 4072 Australia centre for Clean Energy and Environment Griffith University Gold Coast 4222 Australia queensland Micro-and nanotechnology centre Griffith University Nathan 4111 Australia

There is a great demand for a sufficient and sustainable energy supply. Hence, the search for applicable hydrogen storage materials is extremely important owing to the diversified merits of hydrogen energy. In this regard, ammonia borane （NH3BH3, AB） containing 19.6wt-% hydrogen has been considered as a promising material for hydrogen storage applications to realize the ＂hydrogen economy＂, but with limits from slow kinetics of hydrogen release and by-product of trace gases such as ammonia and borazine. In this review, we introduce the recent research on AB, regarding to the nanoconfinement effect on improving the kinetics at a relatively low temperature and the prevention/reduction of undesirable gas formation.

关键词： ammonia borane hydrogen storage

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Nanoemulsions for drug delivery

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Particuology 2022年第5期20卷 85-97页

作者： Russell J.Wilson Yang Li Guangze Yang Chun-Xia Zhao Australian Institute for Bioengineering and nanotechnology The University of QueenslandSt Lucia Queensland 4072Australia

Emulsions are liquid-liquid dispersions with one liquid phase dispersed in the other liquid phase as small *** are nano-sized emulsions with sizes ranging from tens to hundreds of nanometers,and have great potential applications in pharmaceutics,foods and cosmetics due to their attractive properties,such as small sizes,high surface area per unit volume,improved dispersion of active hydrophobic components and enhanced *** article provides an overview of nanoemulsions for drug delivery,starting with an introduction of emulsion types,nanoemulsion preparation and nanoemulsion *** play critical roles in producing and stabilizing *** types of surfactants are summarized including small molecule surfactants,particle surfactants,phospholipids,peptide and protein *** the applications of nanoemulsions as nanomedicine in drug delivery are ***,clinical applications of nanoemulsions are discussed.

关键词： Nanoemulsions Surfactants Drug delivery Nanomedicine Peptide surfactant

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Bismuth based photoelectrodes for solar water splitting

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Journal of Energy Chemistry 2021年第10期30卷 517-530,I0014页

作者： Sabiha Akter Monny Zhiliang Wang Muxina Konarova Lianzhou Wang Nanomaterials centre School of Chemical Engineering and Australian Institute for Bioengineering and NanotechnologyThe University of QueenslandSt LuciaQLD 4072Australia

Photoelectrochemical water splitting is a sustainable path to generate valuable hydrogen using sunlight and water as the only *** significant efforts to date,it is still a challenge to achieve photoelectrode with superior performance and long-term *** bismuth-based semiconductor materials have demonstrated excellent visible light harvesting capability and suitable band edge for water ***,we summarized the latest studies conducted on bismuth-based photoelectrodes for photoelectrochemical water ***,photoelectrochemical properties of copper bismuth oxide(CuBi_(2)O_(4)),bismuth ferrites(BiFeO_(3),Bi_(2)Fe_(4)O_(9)),bismuth vanadate(BiVO_(4)),bismuth tungstate(Bi_(2)WO_(6)),bismuth molybdate(Bi_(2)MoO_(6))and bismuth oxyhalids(BiOX,X=I,Cl,Br)are *** to achieve high stability and photolectrochemical performance were discussed in the aspects of nanostructure formation,heterostructure assembly,practical defect engineering,preferential facet growth and oxygen evolution catalyst incorporation.

关键词： Photocathode Photoanode Bismuth Photoelectrochemical water splitting

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