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Interaction between Seizure and Theta Rhythm

Journal of Behavioral and Brain Science 2020年第1期10卷 18-28页

作者： Zakaria I. Nanobashvili Irine G. Bilanishvili Maia D. Barbakadze Tamar Z. Gaixarashvili Salome A. Dolidze Ketevan E. Khujadze Levan X. Nachkebia Nadejda A. Khizanishvili Dep.rtment of Neurop.ysiology I. Beritashvili Center of Experimental Biomedicine Tbilisi Georgia International Caucasus University Tbilisi Georgia p. shotadze tbilisi medical academy Tbilisi Georgia

Recently it was shown by us that combined stimulation of hip.ocamp.s and dorsomedial hyp.thalamus resulted in sup.ression of the electroencep.alograp.ic seizure reactions and, resp.ctively, manifestations of behavioral seizures reduced. It is exp.cted, that augmentation of inhibitory p.ocesses in hip.ocamp.l neurons in the course of dorsomedial hyp.thalamus stimulation can trigger mechanisms p.eventing the develop.ent of ep.lep.iform activity. Because of two imp.rtant characteristics of the hip.ocamp.s—theta rhythm and ep.lep.ogenesis—these ap.ear to be interrelated in resp.ct of their cellular substrates, and as far as theta rhythm may modulate hip.ocamp.l excitability, a study of the functional relationship.between theta rhythm and seizure activity was endeavored. The p.rp.se of this study is to test this p.op.sal by determining the effects on seizures of induction or sup.ression of hip.ocamp.l theta activity. Our findings show that: 1) against background of strong unusual sound stimulation (in our case-sound) blockade of local seizure reactions induced by hip.ocamp.l stimulation occurred;2) the frequency of hip.ocamp.l interictal ep.lep.iform dischargers increased with the transition from the awake state to drowsiness and a slow-wave sleep.p.ase. After the animal came from slow-wave sleep.to p.radoxical sleep. ep.lep.iform activity comp.etely disap.eared;3) at threshold stimulation of hyp.thalamus when electrohip.ocamp.gram shows augmentation of the theta rhythm there is a significant reduction of seizure durations. When at hyp.thalamus stimulation instead of theta rhythm the electrical activity is desynchronized, there occurs a considerable intensification of seizure activity. Therefore, seizure-theta antagonism in our exp.riments could be interp.eted as an adjustment of the inhibitory mechanisms when the theta rhythm is evoked.

关键词： Hip.ocamp.s Seizure Theta Rhythm Rats

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p.essure Changes in p.tients with Chronic Renal Failure Undergoing Hemodialysis

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Op.n Journal of Op.thalmology 2023年第2期13卷 238-247页

作者： Ana Dvalishvili Tatsiana Imshenetskaya New Vision University Tbilisi Georgia Belarusian medical academy of p.st Graduate Education Minsk Belarus

p.rp.se: To determine the effects of hemodialysis on intraocular p.essure (IOp. and to evaluate the correlation of IOp.changes with anterior chamber angle anatomy. p.tients and Methods: The study included 80 eyes of 40 p.tients with chronic renal failure (CRF) undergoing hemodialysis at the High Technology medical Center between October 2018 and October 2021. Hemodialysis (HD) was p.rformed 3 times a week and the duration of the p.ocedure was 3 - 5 hours. The enrolled p.tients were group.d according to the width of the anterior chamber angle. IOp.was evaluated at three different times during HD. Intraocular p.essure was measured in both eyes in an up.ight sitting p.sition with iCare tonometer. Results: According to the study results, there was no statistically significant difference in the axial length between the three measurements (p.= 0.232). In p.tients with normal anterior chamber dep.h, IOp.decreased significantly (68.75%) or did not show any changes in their IOp.during or after the session. In p.tients with moderate narrow-angle (22.5%), IOp.revealed no statistically significant differences. In p.tients with narrow-angle (8.75%), there was a marked increase in IOp. Changes in intraocular p.essure were correlated with the anatomy of the anterior chamber angle. Loss in body weight as a result of hemodialysis was statistically imp.rtant (p.Conclusion: A significant increase in mean was revealed during and after hemodialysis in p.tients with extremely narrow-angle in comp.rison to eyes with wide or moderately anterior chamber angle. Eyes with shallow anterior chambers are at risk of having imp.ired aqueous humor outflow facilities and, as a result, significantly increase IOp.during HD. Because of the high p.evalence of narrow angles in the Caucasian p.p.lation, it is of clinical imp.rtance to investigate the IOp.changes in p.tients on HD. The results of our study sup.ort the idea that iridocorneal angle anatomy is affecting IOp.fluctuation occurring in p.tients w

关键词： Hemodialysis Gonioscop. Intraocular p.essure Anterior Chamber Angle

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Modeling of nanop.rticle-sensitized sp.tially localized dynamic p.otohyp.rthermia in a blood vessel under infrared laser irradiation with a scanning beam

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Journal of Bio-X Research 2023年第3期6卷 79-84页

作者： Vladislav Alexandrovich Oleshchenko Victor Vladimirovich Bezotosnyi Sop.ia Berinski p.ng Ding Victor Yurevich Timoshenko Vac&Las Laboratory TbilisiGeorgia Lebedev p.ysical Institute of the Russian academy of Sciences Leninskiy Prospekt 53119991 MoscowRussia Zhejiang Kangrui Ap.aratus Technology Co. Ltd.Pingshui ShaoxingP.R.China Faculty of p.ysics Lomonosov Moscow State UniversityLeninskie Gory 1119991 MoscowRussia

p.otoheating in a venous blood vessel under near-infrared laser irradiation by a scanning laser beam,which is synchronized with the blood flow velocity,is analyzed numerically by considering the light scattering,absorp.ion,and heat transfer in the blood and surrounding *** scanning regime of the laser irradiation with a wavelength of 1064 nm is found to increase strongly the p.otoheating of the blood while minimizing the overheating of the skin and the tissues surrounding the blood *** show that the p.otoheating effect can be additionally enhanced by light-absorbing nanop.rticles in the *** p.op.sed ap.roach of dynamic laser p.otohyp.rthermia with the scanning laser beam is discussed for p.tential ap.lications in laser p.ototherap..

关键词： blood laser irradiation nanop.rticles p.otohyp.rthermia p.ototherap. simulations

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Extracting the low-energy constant L_(0)^(r)at three flavors from p.on-kaon scattering

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Communications in Theoretical p.ysics 2022年第6期74卷 61-65页

作者： Chaitra Kalmahalli Guruswamy Ulf-G Meißner Chien-Yeah Seng Helmholtz-Institut für Strahlen-und Kernp.ysik and Bethe Center for Theoretical p.ysics Universität BonnD-53115 BonnGermany Institute for Advanced Simulation Institut für Kernphysik and Jülich Center for Hadron PhysicsForschungszentrum JülichD-52425 JülichGermany tbilisi State University 0186 TbilisiGeorgia

based on our analysis of the contributions from the connected and disconnected contraction diagrams to the p.on-kaon scattering amp.itude,we p.ovide the first determination of the only free low-energy constant at O(p.(4)),known as L_(0)^(r),in SU(4|1)p.rtially-Quenched Chiral p.rturbation theory using the data from the Extended Twisted Mass collaboration,L_(0)^(r)(μ=M_(ρ))=0.77(20)(25)(7)(7)(2)·10^(-3).The theory uncertainties originate from the unp.ysical scattering length,the p.ysical low-energy constants,the higher-order chiral corrections,the(lattice)meson masses and the p.on decay constant,resp.ctively.

关键词： lattice QCD p.rtially quenched chiral p.rturbation theory p.on-kaon scattering

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On the structure in the ΛN cross section at the ∑N threshold

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Chinese p.ysics C 2021年第9期45卷 157-166页

作者： Johann Haidenbauer Uf-G.MeiBner Institute for Advanced Simulation Institut fur Kemphysik and Julich Center for Hadron PhysicsForschungszentrum JulichD-52425 JulichGermany Helmholtz-Institut fiir Strahlen-und Kemp.ysik and Bethe Center for Theoretical p.ysics Universitat Bonn53115 BonnGermany tbilisi State University 0186 TbilisiGeorgia

The comp.exity of threshold p.enomena is exemp.ified on a p.ominent and long-known case-the structure in theΛp.cross section(invariant mass sp.ctrum)at the op.ning of the∑N *** mass sp.itting between the∑baryons together with the angular momentum coup.ing in the^(3)S_(1)-^(3)D_(1)p.rtial wave imp.y that,in p.incip.e,up.to six channels are *** hyp.ron-nucleon p.tentials that p.ovide an excellent descrip.ion of the available low-energy Λp.and∑N scattering data,the shap. of the resulting Λp.cross section is discussed and the p.les near the ∑N threshold are *** for a strangeness S=-1 dibaryon is p.ovided,in the form of a(unstable)∑N bound state in the vicinity of the ∑N *** for level shifts and widths of ∑^(-)p.atomic states are given.

关键词： hyp.ron-nucleon interaction dibaryon threshold effects

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利用机器学习研究隐粲五夸克态的性质

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Science Bulletin 2023年第10期68卷 981-989,M0003页

作者：张振宇刘家豪胡继峰王倩 Ulf-G.Meißner Guangdong p.ovincial Key Laboratory of Nuclear Science Institute of Quantum MatterSouth China Normal UniversityGuangzhou 510006China Guangdong-Hong Kong Joint Laboratory of Quantum Matter Southern Nuclear Science Computing CenterSouth China Normal UniversityGuangzhou 510006China Helmholtz-Institut für Strahlen-und Kernp.ysik and Bethe Center for Theoretical p.ysics Universität BonnBonn D-53115Germany Institute for Advanced Simulation Institut für Kernphysik and Jülich Center for Hadron PhysicsForschungszentrum JülichJïlich D-52425Germany tbilisi State University Tbilisi 0186Georgia

机器学习已经在生物、医学、生产等多个领域广泛应用并展现了其优势.最近,机器学习在物理领域也开始逐渐兴起并展现出其独特的优点.该文旨在探索机器学习在强子物理中的应用潜力.作者以隐粲五夸克态p.(4312)、p.(4440)和p.(4457)为例,... 详细信息

机器学习已经在生物、医学、生产等多个领域广泛应用并展现了其优势.最近,机器学习在物理领域也开始逐渐兴起并展现出其独特的优点.该文旨在探索机器学习在强子物理中的应用潜力.作者以隐粲五夸克态p.(4312)、p.(4440)和p.(4457)为例,在强子分子态图像下研究它们的性质.研究表明,神经网络方法和基于χ2的拟合方法都能够阐明基于领头阶接触势的基本物理性质.然而,χ2拟合方法无法区分p.(4440)和p.(4457)的量子数,神经网络方法则可以.由此,作者进一步分析了每个实验数据点对于神经网络预测的影响,以及在拟合方法中每个数据点对于关键物理参数的重要性.通过对比研究,作者发现神经网络方法可以多维度地利用实验数据信息,在强子物理中具有巨大的应用前景.

关键词： Exotic hadrons Machine learning QCD mass sp.ctrum Hidden charm p.ntaquarks

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The p.oton radius:from a p.zzle to p.ecision

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Science Bulletin 2020年第4期65卷 257-258页

作者： Hans-Werner Hammer Ulf-GMeiBner Institut für Kernp.ysik Technische Universitat Darmstadt64289 DarmstadtGermany ExtreMe Matter Institute EMMI GSI Helmholtzzentrum für Schwerionenforschung GmbH64291 DarmstadtGermany Helmholtz Institut für Strahlen-und Kernp.ysik and Bethe Center for Theoretical p.ysics Universitat BonnD-53115 BonnGermany Institute for Advanced Simulation and Institut für Kernp.ysik Forschungszentrum JülichD-52425 JülichGermany tbilisi State University 0186 TbilisiGeorgia

The p.oton charge radius rp.is a fundamental quantity in p.rticle p.ysics,as it challenges our understanding of the so successful Standard Model in the non-p.rturbative regime of the strong *** is defined by the slop. of the p.oton charge form factor GE p.etT at zero momentum transfer,with t the invariant four-momentum transfer *** p.oton charge radius was first indirectly measured in the Nobel p.ize winning electron scattering exp.riments by Hofstadter et al.[1,2],who fitted the form factor data with a dip.le form and extracted the radius from the slop. of the dip.le.

关键词： DISp.RSION-THEORETICAL ANALYSIS FORM-FACTORS NUCLEON SCATTERING HYDROGEN SIZE

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Ep.taxial Lead Selenide Layers over a Wide Range of Their Thickness on Dielectric Substrates

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材料科学与工程（中英文B版） 2013年第2期3卷 97-103页

作者： Arif M. p.shaev Omar I. Davarashvili Megi I. Enukashvili Zaira G. Akhvlediani Revaz G. Gulyaev Larisa p. Bychkova National Aviation academy of Azerbaijan Baku Azerbao'an lv. Javakhishvili tbilisi State University Tbilisi Georgia E. Andronikashvili Institute of p.ysics Tbilisi Georgia

The article deals with the relative deformation in monocrystalline lead selenide layers grown on dielectric substrates KCl, BaF2 and NaCl. It was established that the deformation in the layers was associated with the mismatch between the lattice constants of the layer and the substrate. The tangential lattice constants in relation to the deformation were studied dep.nding on the layers thickness, and their correlation was shown. It is noted that, as the layers thickness decreases, it becomes p.ssible to observe maximum relative deformations on all substrates.

关键词：硒化铅介质基片厚度相对变形晶格常数生长介质氯化钠氟化钡

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The Structure of Thin Ep.taxial Layers of Lead Selenide

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材料科学与工程（中英文A版） 2013年第2期3卷 116-121页

作者： Arif M. p.shaev Omar I. Davarashvili: Zaira G. Akhvlediani: Megi I. Enukashvilit Revaz G. Gulyaev Vladimir p. Zlomanov National Aviation academy Baku Azerbaijan Iv. Javakhishili tbilisi State University Tbilisi Georgia E .Andronikashvili Institute of p.ysics Tbilisi Georgia M. V. Lomonosov Moscow State University Moscow Russia

The article deals with the structure of lead selenide ep.taxial layers, including nanolayers. The investigation is based on the measurements of the half-width of X-ray diffractions lines. It is shown how the sizes of subgrains-crystallites and the strain in layers vary with the layers thickness. The effect of layer growth rates on the tangential lattice constant was studied.

关键词：外延层硒化铅结构薄膜 X-射线晶格常数亚晶粒纳米层

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R&D of back-end electronics for imp.oved resistive p.ate chambers for the p.ase 2 up.rade of the CMS end-cap.uon system

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Radiation Detection Technology and Methods 2022年第3期6卷 306-316页

作者： H.Kou Z.-A.Liu J.Zhao J.Song Q.Hou W.Diao p.Cao W.Gong N.Wang A.Samalan M.Tytgat M.El Sawy G.A.Alves F.Marujo E.A.Coelho F.Torres Da Silva De Araujo E.M.Da Costa H.Nogima A.Santoro S.Fonseca De Souza D.De Jesus Damiao M.Thiel M.Barroso Ferreira Filho K.Mota Amarilo A.Aleksandrov R.Hadjiiska p.Iaydjiev M.Rodozov M.Shop.va G.Sultanov A.Dimitrov L.Litov B.p.vlov p.p.tkov A.p.trov E.Shumka S.J.Qian C.Avila D.Barbosa A.Cabrera A.Florez J.Fraga J.Reyes Y.Assran M.A.Mahmoud Y.Mohammed I.Laktineh G.Grenier M.Gouzevitch L.Mirabito K.Shchablo C.Combaret W.Tromeur G.Galbit A.Luciol X.Chen I.Bagaturia I.Lomidze Z.Tsamalaidze V.Amoozegar B.Boghrati M.Ebraimi E.Zareian M.Mohammadi Najafabadi M.Abbrescia G.Iaselli G.p.gliese F.Loddo N.De Filip.is R.Aly D.Ramos W.Elmetenawee S.Leszki I.Margjeka D.p.esani L.Benussi S.Bianco D.p.ccolo S.Meola S.Buontemp. F.Carnevali L.Lista p.p.olucci F.Fienga A.Braghieri p.Salvini p.Montagna C.Riccardi p.Vitulo E.Asilar J.Choi T.J.Kim S.Y.Choi B.Hong K.S.Lee H.Y.Oh J.Goh I.Yu C.Uribe Estrada I.p.draza H.Castilla-Valdez R.L.Fernandez A.Sanchez-Hernandez E.Vazquez M.Ramirez-Garcia N.Zaganidis A.Radi H.Hoorani S.Muhammad A.Ahmad I.Asghar M.A.Shah W.A.Khan J.Eysermans I.Crotty on behalf of the CMS Muon Group Dep.rtment of p.ysics and Astronomy Ghent UniversityProeftuinstraat 869000 GhentBelgium UniversitéLibre de Bruxelles Avenue Franklin Roosevelt50-1050 BruxellesBelgium Centro Brasileiro p.squisas Fisicas R.Dr.Xavier Sigaud150UrcaRio de JaneiroRio de Janeiro 22290-180Brazil Dep.rtment de Fisica Nuclear e Altas Energias Instituto de FisicaUniversidade do Estado do Rio de JaneiroRua Sao Francisco Xavier524Rio de JaneiroRio de Janeiro 20559-900Brazil Bulgarian academy of Sciences Institute for Nuclear Researches and Nuclear EnergyTzarigradsko Shaussee Boulevard 721784 SofiaBulgaria Faculty of p.ysics University of Sofia5 James Bourchier Boulevard1164 SofiaBulgaria School of p.ysics Peking UniversityBeijing 100871China State Key Laboratory of p.rticle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese academy of Sciences B325Main BuildingNo.19(A)Yuquan RoadShijingshan DistrictBeijing 100049China Universidad de Los Andes Carrera 1No.18A-12BogotáColombia Egyp.ian Network for High Energy p.ysics Academy of Scientific Research and Technology101 Kasr El-Einy St.CairoEgypt Suez University SuezCairo RoadElsalam CitySuez 43522Egypt Center for High Energy p.ysics(CHEp.FU) Faculty of ScienceFayoum UniversityEl-Fayoum 63514Egypt Univ Lyon Univ Claude Bernard Lyon 1CNRS/IN2P3IP2I LyonUMR 582269622 VilleurbanneFrance Georgian Technical University 77 Kostava Str.0175 TbilisiGeorgia School of p.rticles and Accelerators Institute for Research in Fundamental Sciences(IPM)P.O.Box 19395-5531 TehranIran School of Engineering Damghan UniversityDamghan ***Iran INFN Sezione di BariVia Orabona 470126 BariItaly INFN Laboratori Nazionali di Frascati(LNF)Via Enrico Fermi 4000044 FrascatiItaly INFN Sezione di NapoliComplesso University Monte S.AngeloVia Cintia80126 NapoliItaly Dip.rtimento di Ingegneria Elettrica e delle Tecnologie dell’Informazione UniversitàDegli Studi di Napoli Federico II80126 NapoliI

p.rp.se The Large Hadron Collider(LHC)at Europ.an Organization for Nuclear Research is p.anned to be up.raded to the high luminosity *** the luminosity makes muon triggering reliable and ofﬂine reconstruction very *** enhance the redundancy of the Comp.ct Muon Solenoid(CMS)Muon system and resolve the ambiguity of track reconstruction in the forward region,an imp.oved Resistive p.ate Chamber(iRp.)with excellent time resolution will be installed in the p.ase-2 CMS *** iRp. will be equip.ed with Front-End Electronics(FEE),which can p.rform high-p.ecision time measurements of signals from both ends of the *** Back-End Electronics(BEE)need to be researched and develop.d to p.ovide sop.isticated functionalities such as interacting with FEE with shared links for fast,slow control(SC)and data,in addition to trigger p.imitives(Tp.)generation and data acquisition(DAQ).Method The BEE p.ototyp. uses a homemade hardware board comp.tible with the MTCA standard,the back-end board(BEB).BEE interacts with FEE via a bidirectional 4.8 Gbp. op.ical p.ired-link that integrates clock,data,and control *** clock and fast/slow control commands are distributed from BEB to the FEE via the *** up.ink is used for BEB to receive the time information of the iRp.’sﬁred strip. and the resp.nses to the fast/slow control *** have a p.p.lined detector data for clusterﬁnding op.ration,recover(DeMux)the time relationship.of which is changed due to the transmission p.otocol for the continuous incoming MUXed data from *** at each bunch crossing(BX),clusteringﬁred strip. that satisfy time and sp.tial constraints to generate *** incoming raw MUXed detector data and Tp. in a time window and latency based on the trigger signal are read out to the DAQ *** Ethernet(GbE)of SiTCp.and commercial 10-GbE are used as link standards for SC and DAQ,resp.ctively,for the BEB to interact with the *** The joint test results of

关键词： CMS iRp. BEE Tp DAQ SC

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