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HIV Prevalence amongst Pregnant Women Clients Attending Antenatal Clinic at the Faith Alive Foundation and PMTCT Centre, Jos Plateau State

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World Journal of AIDS 2016年第2期6卷 59-64页

作者： Anyaka Charles Oyebode Tinuade Musa Jonah Isichei Mercy Anyaka Ifechi Isichei Christian Department of Obstetrics and Gynaecology University of Jos/Jos University Teaching Hospital Jos Nigeria Faith Alive Foundation and hospital Jos Nigeria Department of Surgery University of Jos/Jos University Teaching Hospital Jos Nigeria our lady of apostles hospital Jos Nigeria Department of Chemical Pathology University of Jos/Jos University Teaching Hospital Jos Nigeria

Introduction: HIV infection and AIDS is a public health problem worldwide, particularly affecting the populace in resource challenged setting like sub-saharan Africa. Women of reproductive age are mostly affected and infected with the HIV disease. Methodology: A cross-sectional study of 216 randomly selected women that booked for antenatal care at the Faith Alive Foundation and PMTCT centre Jos between 1st July to 31st December, 2014 was carried out. Information regarding age, parity, gestational age at booking, educational status and HIV sero-status of the clients was analysed. Screening test was conducted in a serial two step approval using determine and UNIGOLD as the confirmatory test, while STAT-PAK was the tie-beaker with discordant result as per the national algorithm. Positive samples were confirmed by western blot method. Result: A total of 18 women out of the 216 women studied were positive giving a sero-prevalence rate of 8.3%. The highest sero-prevalent rate was amongst 25 - 29 years age group (31.5%). Women of parity 1 - 4 constituted the highest group of 62.9%. Majority of the women 65.7% booked in the second trimester while 26.9% booked in the 3rd trimester. Most of the women 47.2% had secondary school education while only 5.6% of them had no form of education. Conclusion: HIV infection prevalence rate among antenatal attendants at Faith Alive Foundation and PMTCT centre Jos is still high. Multisectorial approach and intervention strategies should be further scaled up for the prevention of vertical transmission of the virus. However, it is worth noting that it is mainly an HIV/AIDS hospital which should have affected the outcome.

关键词： HIV Prevalence Antenatal Clinic Faith Alive Foundation and PMTCT Centre Jos Plateau State

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Vivax malaria:a rare cause of thalamic bleed

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Asian Pacific Journal of Tropical Medicine 2012年第8期5卷 665-666页

作者： Jaydeep Sarkar Biku Naik Atul Gawande Atul Goel Department of Internal Medicine Lady Hardinge Medical CollegePGIMERand Dr.RML HospitalNew DelhiIndia

Most common cause of thalamic bleed is hypertension;other causes are arteriovenous malformation,aneurysm,bleeding thathesis,drugs,amyloid angiopathy,tumor *** present a case of Plasmodium vivax(***) malaria with unusual site of bleeding *** thalamus of *** the best of our knowledge,this is the first reported case of thalamic bleed caused by vivax malaria in absence of severe thrombocytopenia/disseminated intravascular coagulation (DIC).

关键词： Malaria Plasmodium vivax Bleed Thalamus Rapid malaria test

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Citation classics in pediatrics: a bibliometric analysis

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World Journal of Pediatrics 2018年第6期14卷 607-614页

作者： Viswas Chhapola Soumya Tiwari Bobbity Deepthi Sandeep Kumar Kanwal Department of Pediatrics Kalawati Saran Children's Hospital&Lady Hardinge Medical CollegeBangla Sahib RoadNew Delhi 110001India

Background Citation analysis provides insights into the history and developmental trajectory of scientific fields. our objec-tive was to perform an analysis of citation classics in the journals of pediatric specialty and to examine their characteristics. Methods Initially, all the journals listed under the category of pediatrics (n = 120) were identified using Journal Citation Reports. Web of science database was then searched (1950–2016) to select the top-100 cited articles in the above identified pediatric journals. The top-100 cited article were categorized according the study design, sub-specialty, country, institutional affiliation, and language. Results The top-100 articles were published in 18 different journals, with Pediatrics having the highest numbers (n = 40), followed by The Journal of Pediatrics (n = 17). The majority (n = 62) of classics were published after 1990. The most cited article had citation count of 3516 and the least cited had a citation count of 593. The USA (n = 71) was the most commonly represented country, and 60 institutions contributed to 100 articles. Fifteen authors contributed to more than one classic as first or second author. Observational study (n = 55) was the commonest study design across all decades, followed by reviews (n = 12), scale development studies (n = 11), and guidelines (n = 11). Among the pediatric sub-specialties, growth and development articles were highly cited (n = 24), followed by pediatric psychiatry and behavior (n = 21), endocrinology (n = 15), and neonatology (n = 12). Conclusions The top-100 cited articles in pediatrics identify the impactful authors, journals, institutes, and countries. Obser-vational study design was predominant—implying that inclusion among citation classics is not related to soundness of study design.

关键词： Bibliometrics Citation analysis Citation count Publishing/trends Scientometrics

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Prognostic Factors to Reduce ICU Overtriage in Elderly Patients with Isolated Mild Traumatic Brain Injury

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Surgical Science 2023年第7期14卷 517-532页

作者： Tomas Jacome Chris LaBorde Richard Lewis Danielle Tatum our lady of the Lake Regional Medical Center Baton Rouge LA USA LSU Health-Baton Rouge Baton Rouge LA USA

Introduction: Elderly patients with mild traumatic brain injury (mTBI) are frequently admitted to an intensive care unit (ICU), which is potentially both harmful and unnecessary. It is not known which patients may be safely observed in a non-ICU setting, potentially improving ICU utilization. The purpose of this study was to identify factors that predict which geriatric patients with traumatic brain injury may be admitted to a level of care other than the ICU. Methods: Adults ≥65+ years admitted with positive radiologic study demonstrating isolated mTBI (defined as Glasgow Coma Scale (GCS) 13 - 15) that was initially managed nonoperatively between January 2011-December 2016 were identified. Primary outcomes evaluated included over triage and Glasgow Outcome Scale (GOS). Results: 207 were identified. Most patients presented with GCS 15 (77.8%) and were admitted to ICU (85.5%). 27% (n = 55) met overtriage criteria. The most common TBI was subdural hemorrhage (SDH) (48.8%) followed by subarachnoid hemorrhage (SAH) (22.2%). Hemorrhage progression developed in 8.7% of subjects, but there was no difference across TBI type. 21.7% of patients developed a ≥2 point decrease in GCS during their hospital stay. Upon discharge, 89.9% had a GOS ≥ 4 - 5. Presence/type of a single intracranial hemorrhage (ICH) was not significantly associated with outcome, but presence of bilateral or multiple lesions was significantly associated with poor outcome (p = 0.04). Conclusions: Overtriage of patients to an ICU is costly, resource intensive, and avoidable. Here, we suggest a conservative framework to assist the determination of which patients can be safely observed in non-ICU setting. Future studies should determine if this framework is generalizable to the entire geriatric population who present with mTBI.

关键词： Traumatic Brain Injury Geriatric Trauma Overtriage Intensive Care Unit Outcomes

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2D vs 3D laparoscopic right colectomy:A propensity score-matching comparison of personal experience with systematic review and meta-analysis

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World Journal of Gastrointestinal Surgery 2021年第6期13卷 597-619页

作者： Gianluca Costa Pietro Fransvea Luca Lepre Fabio Rondelli Alessandro Costa Michela Campanelli Giorgio Lisi Maria Rosaria Mastrangeli Giovanni Guglielmo Laracca Giovanni Maria Garbarino Graziano Ceccarelli Surgery Center Campus Bio-MedicoRome 00128Italy Department of Emergency and Trauma Surgery Fondazione Policlinico Universitario A.Gemelli IRCCSRome 00168Italy General Surgery Unit Santo Spirito in Sassia HospitalRome 00193Italy Department of Surgical Science University of PerugiaSanta Maria Teaching HospitalTerni 05100Italy Catholic University“our lady of Good Council”School of Medicine Tirane 1023Albania Department of Emergency Surgery Tor Vergata University HospitalRome 00133Italy Department of General Surgery Sant'Eugenio HospitalRome 00144Italy Department of Medical Surgical Science and Translational Medicine Sapienza University of RomeSant'Andrea HospitalRome 00189Italy General Surgery Unit San Giovanni Battista HospitalFoligno 06034Italy

BACKGROUND The benefits of laparoscopic approach for right colectomy have been well ***,the technical difficulty to construct the intra-corporeal anastomosis is still *** To analyze the results of 3D and 2D laparoscopic right colectomy and to compare it to the published series through a systematic review and *** A retrospective study with propensity score matching analysis of patients undergoing laparoscopic right colectomy at Umbria2 hospitals from January 2014 to March 2020 was performed.A systematic review was accomplished comparing 2D and 3D right *** In the personal series 47 patients of the 2D group were matched to 47 patients of the 3D *** 3D group showed a favorable trend in terms of mean operative time(170.7±32.9 min vs 183.8±35.4 min;P=0.053)and a significant lower anastomotic time(16.9±2.3 min vs 19.6±2.9 min,Pour series were included in the meta-analysis with 551 patients(2D group:291;3D group:260).The pooled analysis demonstrated a significant difference in favour of the 3D group regarding the operative time(Pour series,the advantage of the 3D system becomes evident when CME and/or more complex associated procedure are requested significantly reducing both the total operative and the anastomotic time.

关键词： Colon cancer Right colectomy Laparoscopy Complete mesocolic excision Two-dimensional Three-dimensional

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Endoscopic band ligation and endoscopic hemoclip placement for patients with Mallory-Weiss syndrome and active bleeding

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World Journal of Gastroenterology 2008年第13期14卷 2080-2084页

作者： Young-Seok Cho Hiun-Suk Chae Hyung-Keun Kim Jin-Soo Kim Byung-Wook Kim Sung-Soo Kim Sok-Won Han Kyu-Yong Choi Department of Internal Medicine Uijeongbu St. Mary's Hospital The Catholic University of Korea Ujeongbu 480-717 Korea Department of Internal Medicine Our Lady Mercy Hospital The Catholic University of Korea Bupyeong 403720 Korea Department of Internal Medicine Uijeongbu St. Mary’s Hospital The Catholic University of Korea Ujeongbu 480-717 Korea Department of Internal Medicine Holy Family Hospital The Catholic University of Korea Bucheon 420717 Korea

AIM: To compare the hemostatic efficacy and safety of two mechanical endoscopic methods: endoscopic band ligation (EBL) and endoscopic hemoclip placement (EHP) in patients with actively bleeding Mallory-Weiss syndrome (MWS). METHODS: A prospective randomized study to compare the efficacy and safety of EHP with EBL was performed from January 2002 to August 2005. Forty-one patients with active bleeding from MWS were treated with EHP (n = 21) or EBL (n = 20). RESULTS: There were no significant differences between groups with respect to clinical and endoscopic characteristics. The mean number of hemoclips applied was 3.2 ± 1.5 and the mean number of bands applied was 1.2 ± 0.4. Primary hemostasis was achieved in all patients. Recurrent bleeding was observed in one patient from the EHP group and two from the EBL group. Patients with recurrent bleeding were treated by the same modality as at randomization and secondary hemostasis was achieved in all. There were no significant differences between the two groups in total transfusion amount or duration of hospital stay. No complications or bleeding-related death resulted. CONCLUSION: EHP and EBL are equally effective and safe for the management of active bleeding in patients with Mallory-Weiss syndrome, even in those with shock or comorbid diseases.

关键词： Mallory-Weiss syndrome Hemostasis Endoscopic band ligation Endoscopic clipping

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经导管封堵膜周室间隔缺损后的房室传导阻滞

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世界核心医学期刊文摘（心脏病学分册） 2007年第2期3卷 38-39页

作者： Walsh M.A. Bialkowski J. Szkutnik M. K.P. Walsh 郭俊 Cardiac Department Our Lady's Hospital for Sick Children Crumlin Dublin 8 Ireland.Dr

目的:观察采用Amplatzer装置经导管封堵膜周室间隔缺损(PMVSD)后患者房室传导阻滞的临床表现、治疗和预后。地点:两个国家的三所儿科心脏病学三级转诊中心。结果:有3例患者在术后出现房室传导阻滞,且都在术后10d内发生。

关键词：经导管封堵房室传导阻滞膜周室间隔缺损 Amplatzer 心脏病学类固醇激素

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Extraction and clipping repair of a chicken bone penetrating the gastric wall

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World Journal of Gastroenterology 2008年第12期14卷 1955-1957页

作者： Jin-Soo Kim Hyung-Keun Kim Young-Seok Cho Hiun-Suk Chae Chang-Whan Kim Byung-Wook Kim Sok-Won Han Kyu-Yong Choi Department of Internal Medicine College of Medicine The Catholic University of Korea Uijeongbu St. Mary's Hospital Gyeonggi-do 480-717 Korea Department of Internal Medicine College of Medicine The Catholic University of Korea Holy Family Hospital Gyeonggi-do 420-717 Korea Department of Internal Medicine College of Medicine The Catholic University of Korea Our lady of Mercy Hospital Gyeonggi-do 420-717 Korea

We report a case of gastric penetration caused by accidental ingestion of a chicken bone in a 42-year old woman with a partially wearing denture. Three days ago, she accidentally swallowed several lumps of poorly-chewed chicken. Physical examination disclosed mild tenderness in the periumbilical area. Abdominal Computed tomography (CT) showed a suspicious penetration or perforation of the stomach wall measuring about 3 cm, by a linear radiopaque material at the lesser curvature of the antrum. The end of a chicken bone was very close to but did not penetrate the liver. Endoscopic examination revealed a chicken bone that penetrated into the prepyloric antrum. The penetrating chicken bone was removed with grasping forceps. Five endoscopic clips were applied immediately at the removal site and the periumbilical pain resolved promptly. After removal of the chicken bone, the patient was treated with conservative care for three days, after which she was completely asymptomatic and discharged without complication. To treat gastric penetration by a foreign body, endoclipping can be a useful method in patients with no signs or symptoms of peritoneal irritation.

关键词： Gastric penetration Chicken bone Hemoclip

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Thalidomide effect in endothelial cell of acute radiation proctitis

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World Journal of Gastroenterology 2008年第30期14卷 4779-4783页

作者： Ki-Tae Kim Hiun-Suk Chae Jin-Soo Kim Hyung-Keun Kim Young-Seok Cho Whang Choi Kyu-Yong Choi Sang-Young Rho Suk-Jin Kang Department of Radiology College of Medicine The Catholic University of Korea Uijeongbu St. Mary’s Hospital Department of Internal Medicine College of Medicine The Catholic University of Korea Uijeongbu St. Mary's Hospital Department of Internal Medicine College of Medicine The Catholic University of Korea Our Lady of Mercy Hospital Department of Internal Medicine College of Medicine The Catholic University of Korea Uijeongbu St. Mary’s Hospital Department of Pathology College of Medicine The Catholic University of Korea St. Vincent Hospital

AIM: To determine whether thalidomide prevents microvascular injury in acute radiation proctitis in white rats. METHODS: Fourteen female Wistar rats were used: six in the radiation group, six in the thalidomide group, and two in normal controls. The radiation and thalidomide groups were irradiated at the pelvic area using a single 30 Gy exposure. The thalidomide (150 mg/kg) was injected into the peritoneum for 7 d from the day of irradiation. All animals were sacrificed and the rectums were removed on day 8 after irradiation. The microvessels of resected specimens were immunohistochemically stained with thrombomodulin (TM), von Willebrand Factor (vWF), and vascular endothelial growth factor (VEGF). RESULTS: The microscopic scores did not differ significantly between the radiation and thalidomide groups, but both were higher than in the control group. Expression of TM was significantly lower inthe endothelial cells (EC) of the radiation group than in the control and thalidomide groups (P < 0.001). The number of capillaries expressing vWF in the EC was higher in the radiation group (15.3 ± 6.8) than in the control group (3.7 ± 1.7), and the number of capillaries expressing vWF was attenuated by thalidomide (10.8 ± 3.5, P < 0.001). The intensity of VEGF expression in capillaries was greater in the radiation group than in the control group and was also attenuated by thalidomide (P = 0.003). CONCLUSION: The mechanisms of acute radiation- induced proctitis in the rats are related to endothelial cell injury of microvessel, which may be attenuated with thalidomide.

关键词： Radiation proctitis Von Willebrand factor Thrombomodulin Vascular endothelial growth factor Thalidomide

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A squamous metaplasia in a gastric ulcer scar of the antrum

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World Journal of Gastroenterology 2008年第8期14卷 1296-1298页

作者： Young-Seok Cho Jin-Soo Kim Hyung-Keun Kim Jeong-Seon Ji Byung-Wook Kim Hiun-Suk Chae Sok-Won Han Kyu-Yong Choi In-Sik Chung Department of Internal Medicine College of Medicine The Catholic University of Korea Uijeongbu St. Mary's Hospital Gyeonggi-do 480-717 Korea Department of Internal Medicine College of Medicine The Catholic University of Korea Our Lady of Mercy Hospital Gyeonggi-do Korea Department of Internal Medicine College of Medicine The Catholic University of Korea Holy Family Hospital Gyeonggi-do Korea Department of Internal Medicine College of Medicine The Catholic University of Korea Kangnam St. Mary’s Hospital Seoul Korea

An 81-year-old man presented with epigastric pain and weight loss for one month. He had a past history of pulmonary tuberculosis, 10 years ago. We performed a gastroscopy, which showed a linear depressed whitish gastric ulcer scar (0.8 cm in length) in the posterior wall of the prepyloric antrum. The result of biopsy was reported as squamous epithelium. Immunohistochemical staining using an antibody to high molecular weight cytokeratin (HMC) revealed positive staining in the squamous epithelium. Two years later, the lesion was followed up. The lesion remained at same site endoscopically, but no squamous epithelium could be seen microscopically.

关键词： Squamous metaplasia Gastric ulcer scar High molecular weight cytokeratin

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