检索结果-南通市图书馆

Opto-Electronic Advances 2024年第9期7卷 40-52页

作者： Weiqi Wang Zhiwei Huang optical bioimaging laboratory Department of Biomedical EngineeringCollege of Design and EngineeringNational University of SingaporeSingapore 117576

We report a novel stimulated Raman scattering(SRS)microscopy technique featuring phase-controlled light focusing and aberration corrections for rapid,deep tissue 3D chemical imaging with subcellular *** accomplish phasecontrolled SRS(PC-SRS),we utilize a single spatial light modulator to electronically tune the axial positioning of both the shortened-length Bessel pump and the focused Gaussian Stokes beams,enabling z-scanning-free optical sectioning in the *** incorporating Zernike polynomials into the phase patterns,we simultaneously correct the system aberrations at two separate wavelengths(~240 nm difference),achieving a~3-fold enhancement in signal-to-noise ratio over the uncorrected imaging ***-SRS provides>2-fold improvement in imaging depth in various samples(e.g.,polystyrene bead phantoms,porcine brain tissue)as well as achieves SRS 3D imaging speed of~13 Hz per volume for real-time monitoring of Brownian motion of polymer beads in water,superior to conventional point-scanning SRS 3D *** further utilize PC-SRS to observe the metabolic activities of the entire tumor liver in living zebrafish in cellsilent region,unraveling the upregulated metabolism in liver tumor compared to normal *** work shows that PCSRS provides unprecedented insights into morpho-chemistry,metabolic and dynamic functioning of live cells and tissue in real-time at the subcellular level.

关键词： SRS 3D imaging phase-controlled light focusing image aberration corrections deep tissue imaging

Time-of-flight resolved stimulated Raman scattering microscopy using counter-propagating ultraslow Bessel light bullets generation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Light(Science & Applications) 2024年第7期13卷 1427-1440页

作者： Shulang Lin Li Gong Zhiwei Huang optical bioimaging laboratory Department of Biomedical EngineeringCollege of Design and EngineeringNational University of SingaporeSingapore 117576Singapore

We present a novel time-of-flight resolved Bessel light bullet-enabled stimulated Raman scattering(B2-SRS)microscopy for deeper tissue 3D chemical imaging with high resolution without a need for mechanical *** accomplish the tasks,we conceive a unique method to enable optical sectioning by generating the counterpropagating pump and Stokes Bessel light bullets in the sample,in which the group velocities of the Bessel light bullets are made ultraslow(e.g.,vg≈0.1c)and tunable by introducing programmable angular dispersions with a spatial light *** theoretically analyze the working principle of the collinear multicolor Bessel light bullet generations and velocity controls with the relative time-of-flight resolved detection for SRS 3D deep tissue *** have also built the B2-SRS imaging system and present the first demonstration of B2-SRS microscopy with Bessel light bullets for 3D chemical imaging in a variety of samples(e.g.,polymer bead phantoms,biological samples such as spring onion tissue and porcine brain)with high *** B2-SRS technique provides a>2-fold improvement in imaging depth in porcine brain tissue compared to conventional SRS *** method of optical sectioning in tissue using counter-propagating ultraslow Bessel light bullets developed in B2-SRS is generic and easy to perform and can be readily extended to other nonlinear optical imaging modalities to advance 3D microscopic imaging in biological and biomedical systems and beyond.

关键词： Bessel resolved propagating

Phase-modulated multi-foci microscopy for rapid 3D imaging

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Photonics Research 2024年第7期12卷 1548-1555页

作者： WEIQI WANG LI GONG ZHIWEI HUANG optical bioimaging laboratory Department of Biomedical EngineeringCollege of Design and EngineeringNational University of SingaporeSingapore 117576Singapore

3D imaging technology is pivotal in monitoring the functional dynamics and morphological alterations in living cells and ***,conventional volumetric imaging associated with mechanical z-scanning encounters challenges in limited 3D imaging speed with inertial ***,we present a unique phase-modulated multifoci microscopy (PM^(3)) technique to achieve snapshot 3D imaging with the advantages of extended imaging depths and adjustable imaging intervals between each focus in a rapid *** accomplish the tasks,we utilize a spatial light modulator (SLM) to encode the phases of the scattered or fluorescence light emanating from a volumetric sample and then project the multiple-depth images of the sample onto a single charge-coupled device camera for rapid 3D *** demonstrate that the PM^(3)technique provides~55-fold improvement in imaging depth in polystyrene beads phantom compared to the depth of field of the objective lens ***^(3)also enables the real-time monitoring of Brownian motion of fluorescent beads in water at a 15 Hz volume *** precisely manipulating the phase of scattered light on the SLM,PM^(3)can pinpoint the specific depth information in living zebrafish and rapidly observe the 3D dynamic processes of blood flow in the zebrafish *** work shows that the PM^(3)technique developed is robust and versatile for fast 3D dynamic imaging in biological and biomedical systems.

关键词： alterations scattered beads

维普期刊数据库

3D nano-printed geometric phase metasurfaces for generating accelerating beams with complex amplitude manipulation

在线全文

学校读者我要写书评

暂无评论

Science China(Physics,Mechanics & Astronomy) 2024年第6期67卷 86-95页

作者： Tianchen Tang Saima Kanwal Yongzheng Lu Yuelong Li Shuangbao Wu Lei Chen Ziheng Qian Zhouyu Xie Jing Wen Dawei Zhang Research Center of optical Instrument and System Ministry of Education and Shanghai Key Lab of Modern Optical SystemUniversity of Shanghai for Science and TechnologyShanghai 200093China

Metasurface,a forefront in emerging optical devices,has demonstrated remarkable potential for complex amplitude manipulation of light ***,prevailing approaches face challenges in spatial resolution and complexities associated with integrating dynamic phases,impeding the simplified design and reproducible fabrication of ***,we introduce an innovative approach for complex amplitude modulation within 3D nano-printed geometric phase *** approach enables the generation of self-accelerating beams by encoding amplitude through phase-only manipulation,achieving high spatial ***,this method circumvents the conventional need to adjust the geometric parameters of metasurface unit structures for amplitude manipulation,offering a streamlined and efficient route for design and fabrication *** novel methodology holds promise for expedited and low-cost manufacturing of complex amplitude manipulation metasurfaces.

关键词： metasurface complex amplitude manipulation geometric phase 3D nano-printing Airy beam accelerating parabolic beam

维普期刊数据库

Stimulated Raman scattering tomography for rapid three-dimensional chemical imaging of cells and tissue

在线全文

学校读者我要写书评

暂无评论

Multi-carrier Tb/s silicon photonic coherent receiver

Advanced Photonics 2024年第2期6卷 20-31页

作者： Weiqi Wang Zhiwei Huang National University of Singapore College of Design and EngineeringOptical Bioimaging LaboratoryDepartment of Biomedical EngineeringSingapore

Three-dimensional(3D)imaging is essential for understanding intricate biological and biomedical systems,yet live cell and tissue imaging applications still face challenges due to constrained imaging speed and strong scattering in turbid ***,we present a unique phase-modulated stimulated Raman scattering tomography(PM-SRST)technique to achieve rapid label-free 3D chemical imaging in cells and *** accomplish PM-SRST,we utilize a spatial light modulator to electronically manipulate the focused Stokes beam along the needle Bessel pump beam for SRS tomography without the need for mechanical z *** demonstrate the rapid 3D imaging capability of PM-SRST by real-time monitoring of 3D Brownian motion of polystyrene beads in water with 8.5 Hz volume rate,as well as the instant biochemical responses to acetic acid stimulants in MCF-7 ***,combining the Bessel pump beam with a longer wavelength Stokes beam(NIR-II window)provides a superior scattering resilient ability in PM-SRST,enabling rapid tomography in deeper tissue *** PM-SRST technique providestwofold enhancement in imaging depth in highly scattering media(e.g.,polymer beads phantom and biotissue like porcine skin and brain tissue)compared with conventional point-scan *** also demonstrate the rapid 3D imaging ability of PM-SRST by observing the dynamic diffusion and uptake processes of deuterium oxide molecules into plant *** rapid PM-SRST developed can be used to facilitate label-free 3D chemical imaging of metabolic activities and functional dynamic processes of drug delivery and therapeutics in live cells and tissue.

关键词： stimulated Raman scattering tomography deep tissue Raman imaging spatial light modulation

来源：评论

学校读者我要写书评

暂无评论

Science China(Information Sciences) 2024年第1期67卷 284-291页

作者： Zhen WANG Xingfeng LI Jingchi LI Jian SHEN Yong ZHANG Yikai SU State Key lab of Advanced optical Communication Systems and Networks Department of Electronic EngineeringShanghai Jiao Tong University

We propose a silicon polarization-diversity coherent receiver for wavelength-multiplexing transmission without using the large-footprint arrayed waveguide grating(AWG).We have integrated our proposed coherent receiver on the silicon-on-insulator(SOI) platform for high-capacity *** the proposed coherent receiver,high-frequency photocurrent signals from other wavelengths are suppressed by electrical low-pass ***,the signal-signal beat interference(SSBI) generated from each wavelength is eliminated by the balanced *** two features lend to the proposed coherent receiver being free of the mm-scale *** have demonstrated our proposed coherent receiver to detect a 1.12-Tb/s wavelength-division-multiplexed and polarization-division-multiplexed 16-ary quadrature amplitude modulation(PDM-16-QAM) *** compact footprint of the silicon chip promises small-form-factor receivers for future ultra-high-capacity coherent communication systems that require a high integration level and low fabrication cost.

关键词： silicon photonics optical receivers coherent communication wavelength-division-multiplexing(WDM) polarization-division-multiplexing(PDM)

Organic thin-film transistors and related devices in life and health monitoring

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2024年第2期17卷 426-444页

作者： Chenfang Sun Tie Wang Tianjin Key laboratory of Drug Targeting and bioimaging Life and Health Intelligent Research InstituteTianjin University of TechnologyTianjin 300384China

The early determination of disease-related biomarkers can significantly improve the survival rate of ***,a series of explorations for new diagnosis technologies,such as optical and electrochemical methods,have been devoted to life and health *** thin-film transistor(OTFT),as a state-of-the-art nano-sensing technology,has attracted significant attention from construction to application owing to the merits of being label-free,low-cost,facial,and rapid detection with multi-parameter ***,interference from non-specific adsorption is inevitable in complex biological samples such as body liquid and exhaled gas,so the reliability and accuracy of the biosensor need to be further improved while ensuring sensitivity,selectivity,and ***,we overviewed the composition,mechanism,and construction strategies of OTFTs for the practical determination of disease-related biomarkers in both body fluids and exhaled *** results show that the realization of bio-inspired applications will come true with the rapid development of high-effective OTFTs and related devices.

关键词： organic thin-film transistors biosensors biomarkers organic bioelectronics organic semiconductors healthcare

Learnable digital signal processing:a new benchmark of linearity compensation for optical fiber communications

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Light(Science & Applications) 2024年第9期13卷 1931-1943页

作者： Zekun Niu Hang Yang Lyu Li Minghui Shi Guozhi Xu Weisheng Hu Lilin Yi State Key lab of Advanced optical Communication Systems and Networks School of Electronic Information and Electrical EngineeringShanghai Jiao Tong UniversityShanghai 200240PR China

The surge in interest regarding the next generation of optical fiber transmission has stimulated the development of digital signal processing(DSP)schemes that are highly cost-effective with both high performance and low *** benchmarks for nonlinear compensation methods,however,traditional DSP designed with block-by-block modules for linear compensations,could exhibit residual linear effects after compensation,limiting the nonlinear compensation *** we propose a high-efficient design thought for DSP based on the learnable perspectivity,called learnable DSP(LDSP).LDSP reuses the traditional DSP modules,regarding the whole DSP as a deep learning framework and optimizing the DSP parameters adaptively based on backpropagation algorithm from a global *** method not only establishes new standards in linear DSP performance but also serves as a critical benchmark for nonlinear DSP *** comparison to traditional DSP with hyperparameter optimization,a notable enhancement of approximately 1.21 dB in the Q factor for 400 Gb/s signal after 1600 km fiber transmission is experimentally demonstrated by combining LDSP and perturbation-based nonlinear compensation *** from the learnable model,LDSP can learn the best configuration adaptively with low complexity,reducing dependence on initial *** proposed approach implements a symbol-rate DSP with a small bit error rate(BER)cost in exchange for a 48%complexity reduction compared to the conventional 2 samples/symbol *** believe that LDSP represents a new and highly efficient paradigm for DSP design,which is poised to attract considerable attention across various domains of optical communications.

关键词： fiber signal optical

Wideband chaos generation using a VCSEL with intensity modulation optical injection for random number generation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Information Sciences) 2024年第6期67卷 457-458页

作者： Yu HUANG Shuangquan GU Yuhang FENG Yigong YANG Shuiying XIANG Pei ZHOU Nianqiang LI School of Optoelectronic Science and Engineering & Collaborative Innovation Center of Suzhou Nano Science and Technology Soochow University State Key laboratory of Integrated Service Networks Xidian University Key lab of Advanced optical Manufacturing Technologies of Jiangsu Province & Key lab of Modern optical Technologies of Education Ministry of China Soochow University

Physical random numbers have been widely used in modern network society,such as the generation of cryptographic keys for classical and quantum cryptography systems[1].Among the many sources of physical entropy,chaotic semiconductor lasers have attracted wide attention due to their desired characteristics including larger bandwidth,low cost,and monolithic integration[2].

关键词： optical signal processing

Hybrid-integrated 200 Gb/s REC-DML array transmitter based on photonic wire bonding technology

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Chinese Optics Letters 2024年第8期22卷 64-69页

作者： Yuxin Ma Jie Zhao Tongtong Yang Yipeng Mei Zhenxing Sun Jun Lu Shaobo Li Xiang Ma Xiangfei Chen Key laboratory of Intelligent optical Sensing and Manipulation of the Ministry of Education&National laboratory of Solid State Microstructures&College of Engineering and Applied Sciences&Institute of optical Communication Engineering&Nanjing University-Tongding Joint lab for Large-Scale Photonic Integrated Circuits Nanjing UniversityNanjing 210023China optical Communication Research and Development Center 54th Research Institute of China Electronics Technology Group CorporationShijiazhuang 050081China

An 8-channel hybrid-integrated chip for 200 Gb/s(8×25 Gb/s)signal transmission has been *** channels are all within the O-band,and with a spacing of 800 *** core of this chip is a monolithic integrated multi-wavelength laser array of 8 directly-modulated distributed feedback(DFB)*** using the reconstruction equivalent chirp technique,multi-wavelength integration and asymmetric phase shift structures are achieved in the laser *** output laser beams of the array are combined by a planar light-wave circuit,which is hybrid-integrated with the laser array by photonic wire *** results of this transmitter chip show good single-mode working of each unit laser,with a sidemode suppression ratio above 50 dB,and the modulation bandwidth is above 20 *** eye diagrams are obtained in the lasers for 25 Gb/s non-return-to-zero modulation,which implies a total 200 Gb/s transmission rate for the whole chip.

关键词： direct modulation laser array reconstruction equivalent chirp photonic wire bonding hybrid integration

维普期刊数据库