Organic thin-film transistors and related devices in life and health monitoring
作者机构：Tianjin Key Laboratory of Drug Targeting and Bioimaging Life and Health Intelligent Research Institute Tianjin University of Technology Tianjin 300384 China
出 版 物：《Nano Research》
年 卷 期：1000年
主 题：organic thin-film transistors biosensors biomarkers organic bioelectronics organic semiconductors healthcare
摘 要：The early determination of disease-related biomarkers can significantly improve the survival rate of patients. Thus, a series of explorations for new diagnosis technologies, such as optical and electrochemical methods, have been devoted to life and health monitoring. Organic thin-film transistor (OTFT), as a state-of-the-art nano-sensing technology, has attracted significant attention from construction to application owing to the merits of being label-free, low-cost, facial, and rapid detection with multi-parameter responses. Nevertheless, interference from non-specific adsorption is inevitable in complex biological samples such as body liquid and exhaled gas, so the reliability and accuracy of the biosensor need to be further improved while ensuring sensitivity, selectivity, and stability. Herein, we overviewed the composition, mechanism, and construction strategies of OTFTs for the practical determination of disease-related biomarkers in both body fluids and exhaled gas. The results show that the realization of bio-inspired applications will come true with the rapid development of high-effective OTFTs and related devices. Electronic Supplementary Material Supplementary material is available in the online version of this article at 10.1007/s12274-023-5606-1.