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Keratinocyte growth factor-2 and autologous serum potentiate the regenerative effect of mesenchymal stem cells in cornea damage in rats

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International Journal of Ophthalmology(English edition) 2014年第2期7卷 211-219页

作者： Ferda Alpaslan Pinarli Gülsen Okten Umit Beden Tunc Fisgin Mehmet Kefeli Nurten Kara Feride Duru Leman Tomak Department of Medical Biology and Genetics Faculty of Medicine Ondokuz Mayis University Department of Ophthalmology Faculty of MedicineOndokuz Mayis University Department of Pediatric Hematology Faculty of MedicineOndokuz Mayis University Department of Pathology Faculty of Medicine Ondokuz Mayis University Department of Medical Biostatistics Faculty of MedicineOndokuz Mayis University

AIM:To investigate the healing process after severe corneal epithelial damage in rats treated with mesenchymal stem cells(MSCs)cultured with or without keratinocyte growth factor(KGF-2)and autologous serum(AS)on amniotic membrane(AM).Many patients are blind and devastated by severe ocular surface diseases due to limbal stem cell *** marrow-derived MSCs are potential sources for cellbased tissue engineering to repair or replace the corneal tissue,having the potential to differentiate to epithelial ***:The study included 5 groups each including 10 female'Sprague Dawley'rats in addition to20 male rats used as bone marrow *** I rats received AM+MSCs,Group II rats AM+MSCs cultured with KGF-2,Group III rats AM+MSCs cultured with KGF-2+AS,Group IV rats only AM and Group V rats,*** was derived from blood drawn from male rats and bone marrow was obtained from the femur and tibia bones of the same *** effect was evaluated with clinical,histopathological and immunohistochemical *** engraftment was demonstrated via detection of donor genotype(Y+)in the recipient tissue(X)with polymerase chain ***:Corneal healing was significantly better in Groups I-III rats treated with MSC transplantation compared to Group IV and Group V rats with supportive treatment *** best results were obtained in Group III rats with 90%transparency,70%lack of neovascularization,and 100%epithelium damage limited to less than 1/4 of ***:We suggest that culture of MSCs with KGF-2 and AS on AM is effective in corneal repair in case of irreversible damage to limbal stem cells.

关键词： corneal wound healing mesenchymal stem cells keratinocyte growth factor-2 autologous serum amniotic membrane

Effects of environmentally friendly agricultural land protection programs: Evidence from the Lake Seyfe area of Turkey

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Journal of Integrative Agriculture 2016年第8期15卷 1903-1914页

作者： Ismet Boz Department of Agricultural Economics Ondokuz Mayis University

fully supported by the Turkish Scientific Research Council （TUBITAK in Turkish, 110O747）

关键词： sustainable development sustainable agriculture environmental problems diffusion of innovations Lake Seyfe Kirsehir Turkey

Acute pancreatitis caused by leptospirosis: Report of two cases

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World Journal of Gastroenterology 2005年第28期11卷 4447-4449页

作者： Ekrem Kaya Adem Dervisoglu Cafer Eroglu Cafer Polat Mustafa Sunbul Kayhan Ozkan Department of Surgery Uludag university BursaTurkey Department of Surgerym ondokuz mayis university SamsunTurkey Department of Surgery ondokuz mayis university SamsunTurkey Department of Infectious Disease ondokuz mayis university SamsunTurkey

Two cases of acute pancreatitis with leptospirosis are reported in this article. Case 1: A 68-year-old woman,presented initially with abdominal pain, nausea, vomiting,and jaundice. She was in poor general condition, and had acute abdominal signs and symptoms on physical examination. Emergency laparotomy was performed, acute pancreatitis and leptospirosis were diagnosed on the basis of surgical findings and serological tests. The patient died on postoperative d 6. Case 2: A 62-year-old man, presented with fever, jaundice, nausea, vomiting, and malaise. Acute pancreatitis associated with leptospirosis was diagnosed,according to abdominal CT scanning and serological *** patient recovered fully with antibiotic treatment and nutritional support within 19 d.

关键词： Acute pancreatitis, Leptospirosis Infection

Neural network study of hidden-charm pentaquark resonances

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Chinese Physics C 2019年第9期43卷 19-25页

作者： Halil Mutuk Physics Department Faculty of Arts and Sciences Ondokuz Mayis University

Recently,the LHCb experiment announced the observation of hidden-charm pentaquark states Pc(4312),Pc(4440),and Pc(4457)nearΣcDandΣcD**** this present work,we studied these pentaquarks in the framework of the nonrelativistic quark model with four types of *** solved five-body Schrodinger equation by using the artificial neural network method and made predictions of parities for these states,which are not yet determined by *** mass of another possible pentaquark state near the D*Σc*with JP=5/2-is also calculated.

关键词： hidden-charm resonances pentaquark neural networks

Some Aspects of L_(w_1)~r(G) ∩ L(p,q,w_2dμ)(G)

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Chinese Annals of Mathematics,Series B 2009年第3期30卷 311-320页

作者： lker ERYILMAZ Cenap DUYAR Department of Mathematics Sciences and Arts FacultyOndokuz Mayis University

Let G be a locally compact Abelian group with Haar *** authors discuss some basic properties of L_(w_1)~r(G) ∩ L(p,q,w_2dμ)(G) *** the necessary conditions for compact embeddings of the spaces L_(w_1)~r(R^d)∩L(p,q,... 详细信息

关键词： Weighted Lebesgue spaces Weighted Lorentz spaces Compact embeddings

Synthesis and Crystal Structure of Trans-bis(acesulfamato-O)tetraaquazinc(Ⅱ)

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Chinese Journal of Structural Chemistry 2010年第7期29卷 1047-1050页

作者： SAHIN Onur ICBUDAK Hasan B(U|¨)Y(U|¨)KG(U|¨)NG(O|¨)R Orhan Department of Physics Faculty of Arts and SciencesOndokuz Mayis UniversitySamsunTurkey Department of Chemistry Faculty of Arts and SciencesOndokuz Mayis UniversitySamsunTurkey

The title compound, trans-bis（acesulfamato-O）tetraaquazinc（Ⅱ）（I, C8H16N2O12S2Zn）, crystallizes in the triclinic system, space group P1 with a = 5.1638（5）, b = 8.5338（9）, c = 9.9583（9）A, α = 74.325（8）, β = 81.112（7）, γ = 75.800（8）°, V= 407.77（7） A3, Z = 1, F（000） = 236, Rint = 0.085, T= 296 K, the final R = 0.029 and wR = 0.078 for 1832 observed reflections with I〉 2σ（0. The ZnⅡcentre resides on a centre of symmetry and has a distorted octahedral geometry. The basal plane is defined by two carbonyl O atoms of two monodentate trans-oriented acesulfamato ligands and two trans-aqua ligands. The axial positions in the octahedron are occupied by two trans-aqua ligands. Intermolecular O-H…O hydrogen bonds produce R22（8） and R22（16） rings, which lead to two- dimensional polymeric chains.

关键词： crystal structure zinc(Ⅱ) octahedral complex hydrogen bonds

Immediate versus delayed primary nerve repair in the rabbit sciatic nerve

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Neural Regeneration Research 2013年第36期8卷 3410-3415页

作者： Ahmet Piskin Berrin Zühal Altunkaynak Atilla tlak Hicabi Sezgin Ozgür Yazici Süleyman Kaplan Department of Orthopedics and Traumatology School of Medicine Ondokuz Mayis University Department of Histology and Embryology School of Medicine Ondokuz Mayis University Department of Orthopedics and Traumatology School of Medicine Giresun University

It is well known that peripheral nerve injury should be treated immediately in the clinic, but in some instances, repair can be delayed. This study investigated the effects of immediate versus delayed （3 days after injury） neurorrhaphy on repair of transected sciatic nerve in New Zealand rabbits using stereological, histomorphological and biomechanical methods. At 8 weeks after immediate and delayed neurorrhaphy, axon number and area in the sciatic nerve, myelin sheath and epineurium thickness, Schwann cell morphology, and the mechanical property of nerve fibers did not differ obviously. These results indicate that delayed neurorrhaphy do not produce any deleterious effect on sciatic nerve repair.

关键词： neural regeneration delayed peripheral nerve repair sciatic nerve peripheral nerve injurystereology microscopy biomechanics neuroregeneration

Hartree-Fock-Roothaan Calculations for Ground States of Some Atoms Using Minimal Basis Sets of Integer and Noninteger n-STOs

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Chinese Journal of Chemistry 2004年第11期22卷 1262-1266页

作者： GüMü■ Sedat ZSO■AN Telhat Department of Physics Amasya Education Faculty Ondokuz Mayis University 05189 Amasya TURKEYDepartment of Physics Amasya Education Faculty Ondokuz Mayis University 05189 Amasya TURKEY

Hartree-Fock-Roothaan (HFR) calculations for ground states of some atoms, i.e. He, Be, Ne, Ar, and Kr have been performed using minimal basis sets of Slater type orbitals (STOs) with integer and noninteger principal quan-tum numbers (integer n-STOs and noninteger n-STOs). The obtained total energies for these atoms using minimal basis sets of integer n-STOs are in good agreement with those in the previous literature. On the other hand, for the case of minimal basis sets of noninteger n-STOs, although the calculated total energies of these atoms agree well with the results in literature, some striking results have been obtained for atoms Ar and Kr. Our computational re-sults for the energies of atoms Ar and Kr are slightly better than those in literature, by amount of 0.00222 and 0.000054 a.u., respectively. The improvement in the energies of atoms Ar and Kr may result from the efficient cal-culations of one-center two-electron integrals over noninteger n-STOs. For some atomic ions in their ground state, HFR calculations have been carried out using minimal basis sets of noninteger n-STOs. The obtained total energies for these atomic ions are substantially lower than those available in literature.

关键词： Hartree-Fock-Roothaan Slater type orbital

Higher Electric Multipole Moments for Some Polyatomic Molecules from Accurate SCF Calculations

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Communications in Theoretical Physics 2002年第10期38卷 489-492页

作者： Telhat Ozdogan Department of Physics Education Faculty Ondokuz Mayis University Amasya Turkey

Higher electric multipole moments for the ground-state electronic configuration of some polyatomicmolecules, i.e. CH4, NH3, H2O, were calculated from SCF-HFR wavefunctions using Slater-type orbital basis *** calculated results for electric multipole moments of these molecules are in good agreement with the theoretical andexperimental ones.

关键词： electric multipole moments, Slater-type orbitals, HFR approximation