Immediate versus delayed primary nerve repair in the rabbit sciatic nerve

作     者：Ahmet Piskin Berrin Zühal Altunkaynak Atilla tlak Hicabi Sezgin Ozgür Yazici Süleyman Kaplan 

作者机构：Department of Orthopedics and Traumatology School of Medicine Ondokuz Mayis University Department of Histology and Embryology School of Medicine Ondokuz Mayis University Department of Orthopedics and Traumatology School of Medicine Giresun University 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2013年第8卷第36期

页      面：3410-3415页

核心收录：

学科分类：0710[理学-生物学] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100204[医学-神经病学] 10[医学] 

主　　题：neural regeneration delayed peripheral nerve repair sciatic nerve peripheral nerve injurystereology microscopy biomechanics neuroregeneration 

摘      要：It is well known that peripheral nerve injury should be treated immediately in the clinic, but in some instances, repair can be delayed. This study investigated the effects of immediate versus delayed （3 days after injury） neurorrhaphy on repair of transected sciatic nerve in New Zealand rabbits using stereological, histomorphological and biomechanical methods. At 8 weeks after immediate and delayed neurorrhaphy, axon number and area in the sciatic nerve, myelin sheath and epineurium thickness, Schwann cell morphology, and the mechanical property of nerve fibers did not differ obviously. These results indicate that delayed neurorrhaphy do not produce any deleterious effect on sciatic nerve repair.