检索结果-南通市图书馆

Risk factors for intracranial hemorrhage and mortality in adult patients with severe respiratory failure managed using veno-venous extracorporeal membrane oxygenation

引用

Chinese Medical Journal 2022年第1期135卷 36-41页

作者： Xiaojing Wu Min Li Ying Cai Tianshu Zhai Yi Zhang Qingyuan Zhan Sichao Gu Department of Pulmonary and Critical Care Medicine Center for Respiratory MedicineChina-Japan Friendship HospitalBeijing 100029China National Clinical Research Center for Respiratory Diseases Beijing 100029China

Background: Intracerebral hemorrhage (ICH) is one of the most severe complications during veno-venous extracorporeal membrane oxygenation (VV-ECMO). This study aimed to determine the risk factors for ICH and mortality in such patients.Methods: We analyzed the clinical data of 77 patients who received VV-ECMO due to severe respiratory failure from July 2013 to May 2019 at China-Japan Friendship Hospital. Demographical data, laboratory indices, imaging characteristics, and other clinical information were collected. Multivariable logistic regression analyses were performed to identify risk factors for ICH and mortality.Results: Of 77 patients, 11 (14.3%) suffered from ICH, and 36 (46.8%) survived. The survival rate was significantly lower (18.2% [2/11]vs. 51.5% [34/66],P = 0.040) in patients with ICH than in those without ICH. Multivariable analysis revealed that factors independently associated with ICH were diabetes mellitus (adjusted odds ratio [aOR]: 12.848, 95% confidence interval [CI]: 1.129-146.188,P = 0.040) and minimum fibrinogen during ECMO (aOR: 2.557, 95% CI: 1.244-5.252,P = 0.011). Multivariable analysis showed that factors independently associated with mortality were acute hepatic failure during ECMO (aOR: 9.205, 95% CI: 1.375-61.604,P = 0.022), CO2 retention before ECMO (aOR: 7.602, 95% CI: 1.514-38.188,P = 0.014), and minimum platelet concentration during ECMO (aOR: 0.130, 95% CI: 0.029-0.577,P = 0.007).Conclusions: Diabetes mellitus and minimum fibrinogen concentration during ECMO are risk factors for ICH in patients with severe respiratory failure managed using VV-ECMO. This indicated that anticoagulants use and nervous system monitoring should be performed more carefully in patients with diabetes when treated with VV-ECMO due to severe respiratory failure.

关键词： Veno-venous extracorporeal membrane oxygenation Severe respiratory failure Intracranial hemorrhage Mortality Risk factors

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Evolution of the newest diagnostic methods for COVID-19:a Chinese perspective

引用

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2023年第6期24卷 463-484页

作者： Mingtao LIU Jiali LYU Xianhui ZHENG Zhiman LIANG Baoying LEI Huihuang CHEN Yiyin MAI Huimin HUANG Baoqing SUN Department of clinical Laboratory National Center for Respiratory MedicineNational Clinical Research Center for Respiratory DiseaseState Key Laboratory of Respiratory DiseaseGuangzhou Institute of Respiratory Healththe First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou510140China national center for respiratory Medicine National Clinical Research Center of Respiratory DiseaseState Key Laboratory of Respiratory DiseaseGuangzhou Institute of Respiratory Healththe First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510140China Guangzhou Medical University Guangzhou 511495China

Coronavirus disease 2019(COVID-19)has continued to spread globally since late 2019,representing a formidable challenge to the world's healthcare systems,wreaking havoc,and spreading rapidly through human contact.With fever,fatigue,and a persistent dry cough being the hallmark symptoms,this disease threatened to destabilize the delicate balance of our global community.Rapid and accurate diagnosis of COVID-19 is a prerequisite for understanding the number of confirmed cases in the world or a region,and an important factor in epidemic assessment and the development of control measures.It also plays a crucial role in ensuring that patients receive the appropriate medical treatment,leading to optimal patient care.Reverse transcription-polymerase chain reaction(RT-PCR)technology is currently the most mature method for detecting viral nucleic acids,but it has many drawbacks.Meanwhile,a variety of COVID-19 detection methods,including molecular biological diagnostic,immunodiagnostic,imaging,and artificial intelligence methods have been developed and applied in clinical practice to meet diverse scenarios and needs.These methods can help clinicians diagnose and treat COVID-19 patients.This review describes the variety of such methods used in China,providing an important reference in the field of the clinical diagnosis of COVID-19.

关键词： Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) Coronavirus disease 2019(COVID-19) Diagnosis Polymerase chain reaction(PCR) Immunoassay Radiography

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asthma mortality among children and adolescents in China,2008–2018

引用

World Journal of Pediatrics 2022年第9期18卷 598-606页

作者： Ting-Ting Liu Jin-Lei Qi Ju Yin Qi Gao Wei Xu Jing-Jing Qiao Peng Yin Mai-Geng Zhou Kun-Ling Shen national clinical research center of respiratory diseases Respiratory DepartmentBeijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthNo.56 Nan-Li-Shi RoadBeijing100045China national clinical research center of respiratory diseases Allergy DepartmentBeijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthBeijing100045China national center for Chronic and Non-Communicable Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijing100050China

Background Asthma mortality among children and adolescents at the national level in China was unreported.The aim of this study was to analyze the mortality of asthma among children and adolescents in China using a nationally representative database.Methods This was a descriptive study using data from the Disease Surveillance Points(DSPs)system.All asthma‐related deaths among children and adolescents aged 0–19 years occurring in DSPs across China from 2008 to 2018 were included.Multilevel Poisson regression models were used to compute the total,age-,gender-,region-and residence-specific asthma mortality rates and to investigate the significance of trends and factors associated with asthma mortality.Data from the national Bureau of Statistics were used to estimate the national asthma deaths.Results Total asthma mortality rate among Chinese children and adolescents fluctuated between 0.020(0.009,0.045)and 0.059(0.025,0.137)per 100,000 and showed an overall downward trend(RR,0.909;95%CI 0.854–0.968)during the study period(2008–2018).Asthma mortality rate was higher in the western China(RR 2.356,95%CI 1.513,3.669)and varied over a ninefold range among DSPs in China.The estimated number of deaths decreased by 51.38%from 2008(n=148;95%CI 58,379)to 2018(n=71;95%CI 34,109).Conclusions Asthma mortality rate among children and adolescents in China was at a low level compared to rates worldwide and decreased significantly from 2008 to 2018.Compared with most countries in the world,the number of asthma deaths was higher in China.

关键词： Adolescent Asthma Child China Mortality

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Epidemiological characteristics of pulmonary tuberculosis in patients with pneumoconiosis based on its social determinants and risk factors in China:a cross-sectional study from 27 provinces

引用

Chinese Medical Journal 2022年第24期135卷 2984-2997页

作者： Huanqiang Wang Huaping Dai Jiayu He Xiangpei Lyu Xinran Zhang Tao Li Department of Occupational respiratory Disease National Institute for Occupational Health and Poison ControlChinese Center for Disease Control and PreventionBeijing 100050China national center for respiratory Medicine National Clinical Research Center for Respiratory DiseasesInstitute of Respiratory MedicineChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100029China Department of Pulmonary and Critical Care Medicine Center of Respiratory MedicineChina-Japan Friendship HospitalBeijing 100029China Department of clinical research and Data Management Center of Respiratory MedicineChina-Japan Friendship HospitalBeijing 100029China

Background:Patients with pneumoconiosis have an elevated risk of contracting pulmonary tuberculosis(PTB)and need particular attention.However,extensive population-based studies on the prevalence of PTB in patients with pneumoconiosis have not been reported in China since 1992.This study aimed to investigate the epidemiological characteristics of PTB in patients with pneumoconiosis based on its social determinants and risk factors in China.Methods:Based on the Commission on Social Determinants of Health(CSDH)framework,data were obtained from a questionnaire survey of patients with pneumoconiosis from China’s 27 provinces(autonomous regions,municipalities)from December 2017 to June 2021.By chi-square and multivariate logistic regression analyses,the epidemiological characteristics of PTB in the patients were identified based on its prevalence and odds ratio(OR)and associated social determinants and risk factors.The population attributable fractions(PAFs)of significant risk factors were also calculated.Results:The prevalence of PTB in patients with pneumoconiosis(n=10,137)was 7.5%(95%confidence interval[CI]:7.0-8.0%).Multivariate logistic regression analysis showed that risk factors included in-hospital exposure to patients with PTB(OR=3.30,95%CI:2.77-3.93),clinically diagnosed cases(OR=3.25,95%CI:2.42-4.34),and northeastern regions(OR=2.41,95%CI:1.76-3.31).In addition,lack of work-related injury insurance(WRII),being born in a rural area,being unemployed,living in western regions,household exposure to patients with PTB,smoking,being underweight,complications of pulmonary bullae or pneumothorax,hospitalization history,and former drinkers among the rural patients were also statistically significant risk factors.Being born in a rural area,lack of WRII and in-hospital exposure to patients with PTB had higher PAFs,which were 13.2%(95%CI:7.9-18.5%),12.5%(95%CI:8.3-16.7%),and 11.6%(95%CI:8.8-14.3%),respectively.Conclusion:The prevalence of PTB in pneumoconiosis remains high in China;it is basically in line with the CSDH m

关键词： Pulmonary tuberculosis Pneumoconiosis Social determinants Risk factors

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Pathogens of first-episode pulmonary infection in 141 children with chronic granulomatous disease

引用

Chinese Medical Journal 2024年第4期137卷 502-504页

作者： Hui Liu Shunying Zhao Haiming Yang Jinrong Liu Hui Xu Xiaolei Tang Yuelin Shen Xiaoyan Zhang Xiaohui Wen Yuhong Zhao Ping Chu Huimin Li Department of Second respiratory Medicine National Clinical Research Center for Respiratory DiseasesBeijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthBeijing 100045China Office of Scientific research Beijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthBeijing 100045China

To the Editor:Chronic granulomatous disease(CGD)is an inherited primary immunodeficiency disease characterized by recurrent life-threatening bacterial or fungal infection and tissue granuloma formation.^([1])Pulmonary infection is the most frequent manifestation,affecting nearly 80%of patients,[2]and remains the major cause of morbidity and mortality in patients with CGD.Details of the pathogenic microorganisms responsible for first-episode pulmonary infection provide information on the spectrum of infection in patients with CGD,help guide the empirical choice of antibiotics or antifungal therapy,and contribute to the early identification and management of CGD.Aspergillus is the commonest causative agent of pulmonary infection,but the distribution of other pathogens varies among countries.^([2–5])Few studies have investigated the etiology of pulmonary infection in CGD in a large cohort in China.

关键词： granuloma infection mortality

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Pharmacological therapy for stable chronic obstructive pulmonary disease

引用

Chronic diseases and Translational Medicine 2023年第2期9卷 82-89页

作者： Ruirui Duan Baicun Li Ting Yang Department of Pulmonary and Critical Care Medicine China-Japan Friendship HospitalBeijingChina national center for respiratory Medicine BeijingChina national center for respiratory Medicine Laboratories BeijingChina Institute of respiratory Medicine Chinese Academy of Medical SciencesBeijingChina National Clinical Research Center for Respiratory Diseases BeijingChina

In recent years,emphasis has shifted from preventing and treating chronic obstructive pulmonary disease(COPD)to early prevention,early treatment,and disease stabilization,with the main goal of improving patients’quality of life and reducing the frequency of acute exacerbations.This review summarizes pharmacological therapies for stable COPD.

关键词： bronchodilator chronic obstructive pulmonary disease inhaled corticosteroid pharmacological therapy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Extracorporeal membrane oxygenation support in 2019 novel coronavirus disease:indications,timing,and implementation

引用

Chinese Medical Journal 2020年第9期133卷 1115-1117页

作者： Min Li Si-Chao Gu Xiao-Jing Wu Jin-Gen Xia Yi Zhang Qing-Yuan Zhan Department of Pulmonary and Critical Care Medicine Center of Respiratory MedicineChina-Japan Friendship HospitalBeijing 100029China National Clinical Research Center for Respiratory Diseases Beijing 100029China

The 2019 novel coronavirus disease(COVID-19)has spread rapidly across Hubei province and to all regions in China owing to its person-to-person transmission and strong invasiveness targeting the lower respiratory tract.[1]By the end of February 15,2020,more than 68,000 cases of COVID-19 pneumonia had been confirmed in China,including over 1600 fatalities.[2]Most infected patients who developed COVID-19 pneumonia suffered from only mild symptoms and then completely recovered.However,in some patients,the phenotype may rapidly progress to acute respiratory distress syndrome(ARDS)and multiorgan failure.The initial clinical data,collected in Wuhan Jinyintan Hospital,showed that ARDS was reported in 12(29%)among 41 confirmed patients.[3]Among the 41 patients,13 patients received medical care in the intensive care unit(ICU),4 patients were provided invasive mechanical ventilations,whereas for two patients,extracorporeal membrane oxygenation(ECMO)treatment was applied.Finally,six of the 41 patients died.The clinical data of 99 confirmed patients from the same hospital demonstrated that 17 in 99 patients developed ARDS;among them,three received ECMO treatment,and 11 died.[4]Another study reported that 22 in 138 cases(16%)developed into ARDS and were admitted into the ICU,of which four received ECMO.[5]

关键词： fir admitted distress

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

In the era of long COVID,can we seek new techniques for better rehabilitation?

引用

Chronic diseases and Translational Medicine 2022年第3期8卷 149-153页

作者： Jiaze He Ting Yang Graduate School of Capital Medial University BejingChina Department of Pulmonary and Critical Care Medicine Center of Respiratory MedicineChina-lapan Friendship HospitalNational Center for Respiratory MedicineInstitute of Respiratory MedicineChinese Academy of Medical SciencesNational Clinical Research Center for Respiratory DiseasesWHO Collaborating Centre for Tobacco Cessation and Respiratory Diseases PreventionBeijingChina

Sincethecoronavirusdisease2019(COVID-19)outbreak has become a pandemic,medical staff and researchers have devotedly managed the disease in terms of pathogens,prevention,and treatment.Even so,the virus continues to wre... 详细信息

关键词： application artificial intelligence long COVID telerehabilitation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Association between clustering of cardiovascular risk factors and resting heart rate in Chinese population:a cross-sectional study

引用

Journal of Geriatric Cardiology 2022年第6期19卷 418-427页

作者： Fu-Yu JING Xiu-Ling WANG Jia-Li SONG Yan GAO Jian-Lan CUI Wei XU Yang YANG Li-Juan SONG Hai-Bo ZHANG Jia-Peng LU Xi LI Xin ZHENG national clinical research center for Cardiovascular diseases NHC Key Laboratory of Clinical Research for Cardiovascular MedicationsState Key Laboratory of Cardiovascular DiseaseFuwai HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeNational Center for Cardiovascular DiseasesBeijingChina national clinical research center for Cardiovascular diseases ShenzhenCoronary Artery Disease CenterFuwai Hospital Chinese Academy of Medical SciencesShenzhenChina

BACKGROUND Epidemiologic studies have explored the association between a single cardiovascular risk factor(CVRF)and resting heart rate(RHR),but the research on the relation of multiple risk factors with RHR remains scarce.This study aimed to explore the associations between CVRFs clustering and the risk of elevated RHR.METHODS In this cross-sectional study,adults aged 35-75 years from 31 provinces were recruited by the China PEACE Million Persons Projects from September 2015 to August 2020.We focused on seven risk factors:hypertension,diabetes mellitus,dyslipidemia,obesity,smoking,alcohol use,and low physical activity.Multivariate logistic regression was used to calculate odds ratios(OR)for elevated RHR(>80 beats/min).RESULTS Among 1,045,405 participants,the mean age was 55.67±9.86 years,and 60.4%of participants were women.The OR(95%CI)for elevated RHR for the groups with 1,2,3,4 and≥5 risk factor were 1.11(1.08-1.13),1.36(1.33-1.39),1.68(1.64-1.72),2.01(1.96-2.07)and 2.58(2.50-2.67),respectively(Ptrend<0.001).The association between the CVRFs clustering number and elevated RHR was much more pronounced in young males than in other age-sex subgroups.Clusters comprising more metabolic risk factors were associated with a higher risk of elevated RHR than those comprising more behavioral risk factors.CONCLUSIONS There was a significant positive association between the CVRFs clustering number and the risk of elevated RHR,particularly in young males.Compared clusters comprising more behavioral risk factors,clusters comprising more metabolic risk factors were associated with a higher risk of elevated RHR.RHR may serve as an indicator of the cumulative effect of multiple risk factors.

关键词： elevated cardiovascular sectional

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Pulmonary aspergillosis with in-situ pulmonary artery thrombosis: to anti-coagulate or not?

引用

Chinese Medical Journal 2019年第14期132卷 1742-1744页

作者： Zhi-Bo Liu Wan-Mu Xie Zhen-Guo Zhai Bin Cao Jun Wan Department of Pulmonary and Critical Care Medicine Center of Respiratory MedicineChina-Japan Friendship Hospital/Institute of Respiratory MedicineChinese Academy of Medical Sciences/National Clinical Research Center for Respiratory DiseasesBeijing 100029China

Aspergillus is widespread in the environment and causes a variety of tracheobronchial and pulmonary disorders,depending upon the alterations of immune status of hosts.[1] Among the spectrum of pulmonary aspergillosis (PA),allergic bronchopulmonary aspergillosis,and most chronic pulmonary aspergillosis are considered as noninvasive diseases,whereas invasive pulmonary aspergillosis (IPA) and subacute invasive pulmonary aspergillosis (SAIA) may cause tissue invasion.

关键词： pulmonary artery thrombosis pulmonary aspergillosis (PA) invasive pulmonary aspergillosis (IPA) subacute invasive pulmonary aspergillosis (SAIA)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：