Extracorporeal membrane oxygenation support in 2019 novel coronavirus disease:indications,timing,and implementation

作     者：Min Li Si-Chao Gu Xiao-Jing Wu Jin-Gen Xia Yi Zhang Qing-Yuan Zhan Li Min;Gu Si-Chao;Wu Xiao-Jing;Xia Jin-Gen;Zhang Yi;Zhan Qing-Yuan

作者机构：Department of Pulmonary and Critical Care MedicineCenter of Respiratory MedicineChina-Japan Friendship HospitalBeijing 100029China National Clinical Research Center for Respiratory DiseasesBeijing 100029China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2020年第133卷第9期

页      面：1115-1117页

核心收录：

学科分类：1002[医学-临床医学] 10[医学] 

基　　金：This study was supported by grants from the National Key Research and Development Program of China(No.2016YFC1304300) Chinese Academy of Medical Sciences(CAMS)Innovation Fund for Medical Sciences(No.2018-I2M-1-003) Non-profit Central Research Institute Fund of CAMS(No.2019TX320006)。 

主　　题：fir admitted distress 

摘      要：The 2019 novel coronavirus disease(COVID-19)has spread rapidly across Hubei province and to all regions in China owing to its person-to-person transmission and strong invasiveness targeting the lower respiratory tract.[1]By the end of February 15,2020,more than 68,000 cases of COVID-19 pneumonia had been confirmed in China,including over 1600 fatalities.[2]Most infected patients who developed COVID-19 pneumonia suffered from only mild symptoms and then completely recovered.However,in some patients,the phenotype may rapidly progress to acute respiratory distress syndrome(ARDS)and multiorgan failure.The initial clinical data,collected in Wuhan Jinyintan Hospital,showed that ARDS was reported in 12(29%)among 41 confirmed patients.[3]Among the 41 patients,13 patients received medical care in the intensive care unit(ICU),4 patients were provided invasive mechanical ventilations,whereas for two patients,extracorporeal membrane oxygenation(ECMO)treatment was applied.Finally,six of the 41 patients died.The clinical data of 99 confirmed patients from the same hospital demonstrated that 17 in 99 patients developed ARDS;among them,three received ECMO treatment,and 11 died.[4]Another study reported that 22 in 138 cases(16%)developed into ARDS and were admitted into the ICU,of which four received ECMO.[5]