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Remote monitoring of implantable defibrillators is associated with fewer inappropriate shocks and reduced time to medical assessment in a remote and rural area

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World Journal of Cardiology 2021年第3期13卷 46-54页

作者： Kara Callum Claudia Graune Elizabeth Bowman Edward Molden Stephen J Leslie Department of Cardiology NHS HighlandInverness IV23UJUnited Kingdom

BACKGROUND Implantable cardioverter defibrillators(ICDs)and cardiac resynchronisation therapy with defibrillators(CRT-D)reduce mortality in certain cardiac patient ***,inappropriate shocks pose a problem,having both adverse physical and psychological effects on the *** advances in device technology now allow remote monitoring(RM)of devices to replace clinic follow up *** allows real time data to be analysed and actioned and this may improve patient *** To determine if RM in patients with an ICD is associated with fewer inappropriate shocks and reduced time to medical *** This was a single centre,retrospective observational study,involving 156 patients implanted with an ICD or CRT-D,followed up for 2 years post *** appropriate and inappropriate shocks were recorded along with cause for inappropriate shocks and time to medical *** RM was associated with fewer inappropriate shocks(13.6%clinic vs 3.9%RM;P=0.030)and a reduced time to medical assessment(15.1±6.8 vs 1.0±0.0 d;P<0.001).CONCLUSION RM in patients with an ICD is associated with improved patient outcomes.

关键词： Implantable cardioverter defibrillator Inappropriate shocks Remote monitoring Cardiac patients Heart failure Arrythmia

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Barriers and facilitators to participating in cardiac rehabilitation and physical activity:A cross-sectional survey

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World Journal of Cardiology 2022年第2期14卷 83-95页

作者： Matthew James Fraser Stephen J Leslie Trish Gorely Emma Foster Ronie Walters Division of Biomedical Science University of the Highlands and IslandsInverness IV23JHUnited Kingdom Department of Cardiology NHS HighlandInverness IV23UJUnited Kingdom Department of Nursing and Midwifery University of the Highlands and IslandsInverness IV23JHUnited Kingdom Cardiac Unit nhsH NHS HighlandInverness IV23JHUnited Kingdom

BACKGROUND Cardiovascular diseases(CVD)have been shown to be the greatest cause of death worldwide and rates continue to *** is recommended that CVD patients attend cardiac rehabilitation(CR)following a cardiac event to reduce mortality,improve recovery and positively influence behaviour around CVD risk *** the recognised benefits and international recommendations for exercisebased CR,uptake and attendance remain suboptimal.A greater understanding of CR barriers and facilitators is required,not least to inform service *** understanding current cardiac patients’attitudes and opinions around CR and physical activity(PA)could inform patient-led ***,through understanding aspects of CR and PA that participants like/dislike could provide healthcare providers and policy makers with information around what elements to target in the *** To investigate participants’attitudes and opinions around CR and *** This study employed a cross-sectional survey design on 567 cardiac *** patients who were referred for standard CR classes at a hospital in the Scottish highlands,from May 2016 to May 2017 were *** part of a larger survey,the current study analysed the free-text responses to 5 open-ended questions included within the wider *** were related to the participants’experience of CR,reasons for non-attendance,ideas to increase attendance and their opinions on *** data were analysed using a 6-step,reflexive thematic *** Two main topic areas were explored:“Cardiac rehabilitation experience”and“physical activity”.Self-efficacy was increased as a result of attending CR due to exercising with similar individuals and the safe environment *** ranged from age and health to distance and starting times of the classes which increased travel time and ***,responses demonstrated a lack of information and communication around the *** h

关键词： Cardiovascular disease Cardiac rehabilitation Physical activity Barriers Facilitators Patient experience

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Radial artery access site complications during cardiac procedures,clinical implications and potential solutions: The role of nitric oxide

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World Journal of Cardiology 2020年第1期12卷 26-34页

作者： Emma M Coghill Timothy Johnson Russell E Morris Ian L Megson Stephen J Leslie Free Radical Research Facility Division of Biomedical SciencesUniversity of the Highlands and IslandsInverness IV23JHUnited Kingdom Johnson Matthey Technology Centre Blount’s CourtSonning CommonReading RG49NHUnited Kingdom School of Chemistry University of St.AndrewsSt Andrews KY169STUnited Kingdom Department of Cardiology NHS HighlandInverness IV23UJUnited Kingdom

Percutaneous coronary intervention for the treatment of coronary artery disease is most commonly performed in the UK through the radial artery,as this is considered to be safer than the femoral ***,despite improvements in technology and techniques,complications can *** most common complication,arterial spasm,can cause intense pain and,in some cases,procedural *** incidence of spasm is dependent on several variables,including operator experience,artery size,and equipment *** antispasmolytic cocktail can be applied to reduce spasm,which usually includes an exogenous nitric oxide(NO)donor(glyceryl trinitrate).NO is an endogenous local vasodilator and therefore is a potential target for anti-spasm ***,systemic administration can result in unwanted side-effects,such as hypotension.A method that adopts local delivery of NO might be *** review article describes the mechanisms involved in radial artery spasm,discusses the advantages and disadvantages of current strategies to reduce spasm,and highlight the potential of NO-loaded nanoporous materials for use in this setting.

关键词： Radial artery Cannulation Spasm Nitric oxide Vasodilation Nanoporous material

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Lophomonas blattarum： Is it Only its Morphology that Prevents its Recognition？

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Chinese Medical Journal 2017年第1期130卷 117-117页

作者： Hugo Cornelis van Woerden Rafael Martinez-Giron nhs highland Assynt House Beechwood Park Inverness IV2 3BW UK Protozoal Respiratory Pathology Research Unit INCLINICA Foundation Oviedo-33207 Asturias Spain

To the Editor： We have read with interest the article published by Li and Gao on Lophomonas blattarum infection,m In it, the authors question whether there is adequate evidence to consider this multiflagellated protozoon of significant importance in the context of the respiratory tract. Mu et al. have also suggested that all the cases diagnosed as pulmonary L. blattarum infection reported in China were misdiagnosed.

关键词：感染呼吸系统基因内皮缩血管肽类前体细胞淋巴母细胞白血病淋巴瘤胰岛素中国

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