检索结果-南通市图书馆

Genomic Surveillance for SARS-CoV-2 Variants: Dominance of XBB Replacement — China, January–June 2023

China CDC weekly 2024年第15期6卷 324-331页

作者： Yenan Feng Qiudong Su Lili Li Xiaozhou He Peihua Niu Xiaojuan Guo Xiang Zhao Jing Tang Zhiyuan Jia Ji Wang Changcheng Wu Baicheng Xia Zhixiao Chen Yuchao Wu Jing Yang Songqi Chen Cao Chen Shiwen Wang Xiaoping Dong National Key Laboratory of Intelligent Tracking and Forecasting for Infectious diseases National Institute for Viral Disease Control and PreventionChinese Center for Disease Control and PreventionBeijingChina NHC Key Laboratory of Medical Virology and Viral diseases National Institute for Viral Disease Control and PreventionChinese Center for Disease Control and PreventionBeijingChina

Introduction:In the first half of 2023,a global shift was observed towards the predominance of XBB *** faced a significant epidemic between late 2022 and early 2023 due to Omicron subvariants BA.5.2 and *** study aims to depict the evolving variant distribution among provincial-level administrative divisions(PLADs)in China and explore the factors driving the predominance of XBB ***:Sequences from local and imported coronavirus disease 2019(COVID-19)cases recorded between January 1 and June 30,2023,were *** study analyzed the changing distribution of viral variants and assessed how the prior dominance of specific variants,XBB subvariants,and imported cases influenced the prevalence of the XBB replacement ***:A total of 56,486 sequences were obtained from local cases,and 8,669 sequences were from imported *** in April,there was a shift in the prevalence of XBB from imported to local cases,with varying dominance among *** PLADs previously high in BF.7,the rise of XBB was delayed.A positive correlation was found between XBB proportions in imported cases from January to March and local cases in *** distribution pattern of XBB subvariants differed between local and imported cases within the same *** significant differences were noted in the replacement rates of XBB ***:The timing of XBB dominance differed among various PLADs in China in the first half of 2023,correlating closely with the prevalence of XBB variants among imported cases.

关键词： dominance imported distribution

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Prevalence and serotype distribution of nasopharyngeal carriage of Streptococcus pneumoniae among healthy children under 5 years of age in Hainan Province, China

引用

Infectious diseases of Poverty 2024年第1期13卷 42-52页

作者： Jian Wang Li Qiu Shuang Bai Wei Zhao Ao Zhang Jing Li Jun-Nan Zhang Shan-Shan Zhou Ren Qiu Zhu Huang Jv-Xia Liu Ting-Bin Wang Xue Sun Jiang Wu Qun Zheng Bin He Min Lv Beijing center for Disease Prevention and control BeijingChina Beijing Research center for Respiratory Infectious diseases BeijingChina Hainan Provincial center for Disease control and Prevention HaikouChina Haikou center for Disease control and Prevention HaikouHainanChina Wanning center for Disease control and Prevention WanningHainanChina Baisha County center for Disease control and Prevention BaishaHainanChina Qiongzhong County center for Disease control and Prevention QiongzhongHainanChina

Background The thirteen-valent pneumococcal conjugate vaccine(PCV13)is not included in the national immu-nization program and is administered voluntarily with informed consent in *** preparation for assessing the impact of pilot introduction in Hainan Province,we conducted a carriage study among children under 5 years of age from four locations in Hainan Province,*** From March to June 2022,nasopharyngeal(NP)swabs,collected from healthy children aged younger than 59 months who lived in the 4 different locations(Haikou,Wanning,Baisha and Qiongzhong)in Hainan Province,were tested for pneumococcus using conventional *** isolates were serotyped using the Quel-lung *** factors associated with pneumococcal colonization were assessed using univariate analysis and multivariable logistic regression adjusting for age,daycare attendance and other *** Pneumococcus was isolated in 710(30.4%)of the 2333 children *** 737 pneumococci,29 serotypes were identifed;60.9%were PCV13 serotypes;the most common vaccine serotypes were 6B(20.4%),19F(13.0%),6A(11.9%)and 23F(6.1%);and the most common nonvaccine serotypes were 23A(12.9%),34(6.1%)and nontypeable(NT)pneumococci(5.6%).Children vaccinated with PCV13 had lower carriage(17.7%vs 32.5%;P=0.0001)and fewer PCV13 serotypes(41.9%vs 62.7%;P=0.0017)compared to unimmunized *** adjustment,NP carriage Was higher among children attending daycare(aOR=2.3,95%CI:1.7-3.2),living in rural areas(aOR=1.4,95%CI:1.1-1.8),living with siblings(aOR=1.3,95%CI:1.0-1.6)and whose mothers had completed senior high/technical sec-ondary school(aOR=1.5,95%CI:1.1-2.0).In contrast,completion of 3-4 doses of PCV13 were associated with a lower carriage rate(aOR=0.6,95%CI:0.4-0.9).Conclusions We established the baseline of pneumococcal carriage,serotype distribution and PCV13 immuni-zation rates among healthy children under 5 years of age in Hainan Province,prior to the introduction of PCV13 into th

关键词： Pneumococcus Nasopharyngeal carriage Serotypes distribution Children Hainan Province China

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

First Case Report of Cystic Echinococcosis Caused by G7 Genotype Echinococcus intermedius Confirmed by Genetic Sequencing—Southern China,December 2023

引用

China CDC weekly 2024年第23期6卷 558-562页

作者： De Wu Jiayi Zhang Jieling Wang Yangyang Zhao Lei Wang Qiang Mao Haisen Lin Gang Yao Guanting Zhang Xu Wang Chuizhao Xue Ying Wang Jingdiao Chen Parasitic Disease Prevention and control Institute Guangdong Center for Disease Control and PreventionGuangzhou CityGuangdong ProvinceChina Epidemic Prevention and control Institute Zhuhai Center for Disease Control and PreventionZhuhai CityGuangdong ProvinceChina Department of Prevention&Healthcare Zhuhai First People's HospitalZhuhai CityGuangdong ProvinceChina National Institute of Parasitic diseases Chinese Center for Disease Control and Prevention(Chinese Center for Tropical Diseases Research)ShanghaiChina

What is already known about this topic?Echinococcosis exhibits a global *** China,the primary endemic area is the northwest *** December 2023,we documented a case of echinococcosis in an individual lacking any travel or residential history in endemic *** is added by this report?This is the first laboratory-confirmed case of hepatic echinococcosis reported in Guangdong Province,associated with the G7 genotype of Echinococcus granulosus(***).The most probable mode of transmission is a local infection resulting from *** introduced from endemic *** are the implications for public health practice?As the circulation of agricultural products increases,it is essential to enhance the quarantine and management of livestock from epidemic areas to prevent and control the spread of echinococcosis to non-epidemic regions.

关键词： travel fir northwest

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Epidemiological Characteristics of Mpox Cases-China,2023

引用

China CDC weekly 2024年第26期6卷 619-623页

作者： Ruiqi Ren Chao Li Wenqing Bai Yali Wang Dan Li Fan Ding Niu Yan Qi Wang Nijuan Xiang Lianmei Jin Lei Zhou Wenling Wang Fan Lyu Peilong Li Dapeng Zhang Yan Li Quanyi Wang Qun Li Guoqing Shi National Key Laboratory of Intelligent Tracking and Forecasting for Infectious diseases Chinese Center for Disease Control and PreventionBeijingChina Chinese center for Disease control and Prevention BeijingChina National Institute for Viral Disease control and Prevention Chinese Center for Disease Control and PreventionBeijingChina National center for AIDS/STD control and Prevention Chinese Center for Disease Control and PreventionBeijingChina Guangdong Provincial center for Disease control and Prevention Guangzhou CityGuangdong ProvinceChina Beijing Municipal center for Disease Prevention and control BeijingChina

Summary What is already known about this topic?Since May 2022,a global outbreak of mpox has emerged in more than 100 non-endemic *** of December 2023,over 90,000 cases had been *** outbreak has predominantly affected men who have sex with men(MSM),with sexual contact identified as the principal mode of *** is added by this report?Since June 2023,China has faced an occurrence of mpox,predominantly affecting the MSM *** 90%of those affected reported engaging in homosexual behavior within 21 days prior to symptom onset,a trend that aligns with the global outbreak *** prompt identification of cases,diligent tracing of close contacts,and the implementation of appropriate management strategies have successfully mitigated the spread of mpox virus in *** are the implications for public health practice?We propose that mpox is transmitted locally within *** from our experiences in controlling the virus spread,it is crucial to investigate and formulate effective surveillance and educational ***,we must encourage high-risk populations to promptly seek medical care upon the onset of symptoms.

关键词： prompt Drawing spread

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Diagnosis,Treatment,and Associated Factors Among Patients with HCV Infection—Jiangsu Province,China,2004–2020

引用

China CDC weekly 2024年第1期6卷 1-5,I0001-I0003页

作者： Dandan Yang Jing Lu Zhi Zhang Chuanwu Sun Zhuping Xu Yao Qi XiaoXia Liu Huan Ding Feifei Chai Zhengdong Zhang Baoli Zhu Department of Genetic Toxicology The Key Laboratory of Modern Toxicology of Ministry of EducationCenter for Global HealthSchool of Public HealthNanjing Medical UniversityNanjing CityJiangsu ProvinceChina Department of Sexually Transmitted diseases and AIDS Center for Disease Control and Prevention of Jiangsu ProvinceNanjing CityJiangsu ProvinceChina Department of Sexually Transmitted diseases and AIDS Center for Disease Control and Prevention of XuzhouXuzhou CityJiangsu ProvinceChina Department of Sexually Transmitted diseases and AIDS Center for Disease Control and Prevention of WuxiWuxi CityJiangsu ProvinceChina Department of Sexually Transmitted diseases and AIDS Center for Disease Control and Prevention of YanchengYancheng CityJiangsu ProvinceChina Department of Sexually Transmitted diseases and AIDS Center for Disease Control and Prevention of ZhenjiangZhenjiang CityJiangsu ProvinceChina.

What is already known on this topic?The global efforts to address the hepatitis C virus(HCV)are progressing,but there are still significant gaps in the diagnosis and treatment of HCV,leading to an increasing number of deaths related to *** is added by this report?An extensive investigation was conducted to assess HCV RNA diagnosis,treatment uptake,and associated factors among individuals infected with HCV within Jiangsu *** study encompassed a large geographical area and utilized a substantial sample *** are the implications for public health practice?Implementing focused interventions to improve the timely diagnosis of HCV RNA and increase the uptake of HCV treatment could effectively reduce the future burden of HCV-related health problems,deaths,and healthcare *** is essential for achieving the global target of eliminating hepatitis C.

关键词： diagnosis utilized Jiangsu

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Thirty Years of Experience of Acute Flaccid Paralysis Surveillance for Polio — China, 1993–2022

引用

China CDC weekly 2024年第16期6卷 344-349页

作者： Hong Yang Ning Wen Chunxiang Fan Fuzhen Wang Yong Zhang Lei Cao Shuangli Zhu Lixin Hao Dongmei Yan Lei Wang Quanwei Song Miao Wang Yifan Song Chao Ma Zhijie An Lance ERodewald Huaqing Wang Zundong Yin National Key Laboratory of Intelligent Tracking and Forecasting for Infectious diseases(NITFID) BeijingChina National Immunization Program Chinese Center for Disease Control and PreventionBeijingChina Institute for Viral Disease control and Prevention Chinese Center for Disease Control and PreventionBeijingChina

Introduction:Detecting poliovirus infections proves to be highly challenging due to their asymptomatic nature and infectious potential,highlighting the crucial importance of effective detection methods in the context of polio eradication *** many countries,including China,the primary approach for identifying polio outbreaks has been through acute flaccid paralysis(AFP)*** this study,we conducted an evaluation spanning three decades(1993–2022)to assess the effectiveness of AFP surveillance in ***:Data on all AFP cases identified since 1993 and national-level AFP surveillance system quality indicators aligned with the World Health Organization(WHO)standards were collected for *** quality indicators assess surveillance sensitivity,completeness,timeliness of detection notification,case investigation,and laboratory *** sensitivity is determined by the non-polio AFP(NPAFP)detection rate among children under 15 years of ***:Between 1993 and 2022,a total of 150,779 AFP cases were identified and *** this pool,surveillance identified 95 cases of wild poliovirus(WPV)and 24 cases due to vaccinederived *** 1995 onwards,the detection rate of NPAFP cases consistently adhered to the WHO and national standards of≥1 case per 100,000,falling between 1.38 and *** in 1997,all timeliness indicators consistently achieved the criteria of 80%,apart from the consistency in meeting standards set for the rate of positive specimens sent to the national ***:AFP surveillance has been instrumental in China’s accomplishment of maintaining a polio-free *** ongoing adherence to key performance indicators,ensuring sensitivity and prompt specimen collection,demonstrates that AFP surveillance is proficient in detecting poliovirus in *** we move into the post-eradication phase,AFP surveillance remains crucial for the sustained absence of polioviruses in the long term.

关键词： sustained prompt surveillance

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Incidence and warning signs for complications of human brucellosis: a multi-center observational study from China

引用

Infectious diseases of Poverty 2024年第1期13卷 53-62页

作者： Qing-Nan Shi Hui-Jie Qin Qiao-Shan Lu hu Li Zhong-Fa Tao Meng-Guang Fan Mu-Heta Aishan Zeng-Qiang Kou Qiu-Lan Chen Wen-Wu Yin Yan-Ping Zhang National Key Laboratory of Intelligent Tracking and Forecasting for Infectious diseases Chinese Center for Disease Control and PreventionChangbai RoadChangping DistrictBejing 102206China School of Public Health Guangxi Medical UniversityNanningChina Nanning center for Disease control and Prevention NanningChina Guizhou center for Disease control and Prevention GuiyangChina Inner Mongolia center for Disease control and Prevention HohhotChina Xinjiang Uighur Autonomous Region center for Disease control and Prevention UrumqiChina Shandong center for Disease control and Prevention JinanChina

Background Brucellosis is a severe zoonotic disease that is often overlooked, particularly in impoverished countries. Timely identification of focal complications in brucellosis is crucial for improving treatment outcomes. However, there is currently a lack of established indicators or biomarkers for diagnosing these complications. Therefore, this study aimed to investigate potential warning signs of focal complications in human brucellosis, with the goal of providing practical parameters for clinicians to aid in the diagnosis and management of *** A multi-center cross-sectional study was conducted in China from December 2019 to August 2021. The study aimed to investigate the clinical characteristics and complications of patients with brucellosis using a questionnaire survey and medical record system. The presence of warning signs for complications was assessed using univariate and multivariate logistic regression models. Receiver operating characteristic (ROC) curves and the area under the curve (AUC) were used for variable screening and model *** A total of 880 participants diagnosed with human brucellosis were enrolled. The median age of the patients was 50 years [interquartile range (IQR): 41.5-58.0], and 54.8% had complications. The most common organ system affected by complications was the osteoarticular system (43.1%), with peripheral arthritis (30.0%), spondylitis (16.6%), paravertebral abscess (5.0%), and sacroiliitis (2.7%) being the most prevalent. Complications in other organ systems included the genitourinary system (4.7%), respiratory system (4.7%), and hematologic system (4.6%). Several factors were found to be associated with focal brucellosis. These factors included a long delay in diagnosis [odds ratio (OR) = 3.963, 95% confidence interval(CI): 1.906-8.238 for > 90 days], the presence of underlying disease (OR = 1.675, 95%CI: 1.176-2.384), arthralgia (OR = 3.197, 95%CI: 1.986-5.148), eye bulging pain (OR = 3.482, 95%CI:

关键词： Brucellosis Complications Clinical spectrum Warning signs

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Analysis of Epidemiological and Issues Encountered in Case Reports on Echinococcosis—China,2022

引用

China CDC weekly 2024年第6期6卷 100-104页

作者： Yan Kui Shuai Han Xiaojuan Zhang Guangzhong Shi Yale Yu Ruirui Li Peizheng Zhan Hongju Duan Wenbo Luo Benfu Li Shaoqi Ning Yalan Zhang Aiya Zhu Jingbo Xue National Institute of Parasitic diseases Chinese Center for Disease Control and Prevention(Chinese Center for Tropical Diseases Research)National Health Commission Key Laboratory of Parasite and Vector BiologyWorld Health Organization Collaborating Center for Tropical DiseasesNational Center for International Research on Tropical DiseasesShanghaiChina Gansu Provincial center for Disease control and Prevention Lanzhou CityGansu ProvinceChina The center for Disease control and Prevention of Xinjiang Uygur Autonomous Region Urumuqi CityXinjiang Uygur Autonomous RegionChina Xinjiang Production and Construction Corps center for Disease control and Prevention Urumuqi CityXinjiang Uygur Autonomous RegionChina Sichuan Provincial center for Disease control and Prevention Chengdu CitySichuan ProvinceChina Qinhai Institute for Endemic Disease control and Prevention Xining CityQinghai ProvinceChina Ningxia center for Disease control and Prevention Yinchuan CityNingxia Hui Autonomous RegionChina Inner Mongolia Autonomous Region center for Comprehensive Disease control and Prevention Hohhot CityInner Mongolia AutonomousChina Yunnan Institute of Parasitic diseases Puer CityYunnan ProvinceChina Shaanxi Provincial center for Disease control and Prevention Xi'an CityShaanxi ProvinceChina Henan Provincial center for Disease control and Prevention Zhengzhou CityHenan ProvinceChina Guizhou Provincial center for Disease control and Prevention Guiyang CityGuizhou ProvinceChina

Summary What is already known about this topic?Echinococcosis is classified as a Class C infectious disease in *** is endemic in 370 counties located in the agricultural and pastoral regions of western *** is added by this report?This report provides a comprehensive overview of the cases of echinococcosis reported in China in *** a thorough evaluation conducted by provincial CDCs.

关键词： China Ech counties

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

DNA vaccine prime and replicating vaccinia vaccine boost induce robust humoral and cellular immune responses against MERS-CoV in mice

引用

Virologica Sinica 2024年第3期39卷 490-500页

作者： Xiuli Shen Shuhui Wang Yanling Hao Yuyu Fu Li Ren Dan Li Wenqi Tang Jing Li Ran Chen Meiling Zhu Shuo Wang Ying Liu Yiming Shao National Key Laboratory of Intelligent Tracking and Forecasting for Infectious diseases National Center for AIDS/STD Control and PreventionChinese Center for Disease Control and PreventionBeijing 102206China Changping Laboratory Yard 28Science Park RoadChangping DistrictBeijing 102206China State Key Laboratory for Diagnosis and Treatment of Infectious diseases National Clinical Research Center for Infectious DiseasesCollaborative Innovation Center for Diagnosis and Treatment of Infectious DiseasesThe First Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhou 310003China

As of December 2022,2603 laboratory-identified Middle East respiratory syndrome coronavirus(MERS-CoV)infections and 935 associated deaths,with a mortality rate of 36%,had been reported to the World Health Organization(WHO).However,there are still no vaccines for MERS-CoV,which makes the prevention and control of MERS-CoV *** this study,we generated two DNA vaccine candidates by integrating MERS-CoV Spike(S)gene into a replicating Vaccinia Tian Tan(VTT)*** to homologous immunization with either vaccine,mice immunized with DNA vaccine prime and VTT vaccine boost exhibited much stronger and durable humoral and cellular immune *** immunized mice produced robust binding antibodies and broad neutralizing antibodies against the EMC2012,England1 and KNIH strains of ***-Boost immunization also induced strong MERS-S specific T cells responses,with high memory and poly-functional(CD107a-IFN-γ-TNF-α)effector CD8t T *** conclusion,the research demonstrated that DNA-Prime/VTT-Boost strategy could elicit robust and balanced humoral and cellular immune responses against *** study not only provides a promising set of MERS-CoV vaccine candidates,but also proposes a heterologous sequential immunization strategy worthy of further development.

关键词： MERS-CoV VTT vaccine DNA vaccine Humoral and cellular immune responses Prime/boost strategy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Geographically and Temporally Weighted Regression in Assessing Dengue Fever Spread Factors in Yunnan Border Regions

引用

Biomedical and Environmental Sciences 2024年第5期37卷 511-520页

作者： ZHU Xiao Xiang WANG Song Wang LI Yan Fei ZHANG Ye Wu SU Xue Mei ZHAO Xiao Tao National Key Laboratory of Intelligent Tracking and Forecasting for Infectious diseases Chinese Center for Disease Control and PreventionBeijing 102211China Yunnan Institute of Parasitic diseases Pu’er 665000YunnanChina

Objective This study employs the Geographically and Temporally Weighted Regression(GTWR)model to assess the impact of meteorological elements and imported cases on dengue fever outbreaks,emphasizing the spatial-temporal variability of these factors in border *** We conducted a descriptive analysis of dengue fever’s temporal-spatial distribution in Yunnan border *** annual data from 2013 to 2019,with each county in the Yunnan border serving as a spatial unit,we constructed a GTWR model to investigate the determinants of dengue fever and their spatio-temporal heterogeneity in this *** The GTWR model,proving more effective than Ordinary Least Squares(OLS)analysis,identified significant spatial and temporal heterogeneity in factors influencing dengue fever’s spread along the Yunnan ***,the GTWR model revealed a substantial variation in the relationship between indigenous dengue fever incidence,meteorological variables,and imported cases across different *** In the Yunnan border areas,local dengue incidence is affected by temperature,humidity,precipitation,wind speed,and imported cases,with these factors’influence exhibiting notable spatial and temporal variation.

关键词： Dengue fever Meteorological factor Geographically and temporally weighted regression

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：