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慢性盆腔痛：子宫内膜异位症和间质性膀胱炎--腹腔镜进展之一

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中国微创外科杂志 2009年第4期9卷 295-298页

作者： Maurice K. Chung 黄润瀚(翻译) 刘彦(审校) midwest Regional Center for Chronic Pelvic Pain and Bladder Control 310 S Cable RdLimaOH 45805USA 第二军医大学附属长征医院妇产科上海200003

引言引起慢性盆腔痛(chronic pelvic pain,CPP)的妇科疾病包括盆腔粘连、附件包块、子宫内膜异位症、输卵管炎、残余卵巢综合征、盆腔淤血综合征、盆腔炎、子宫腺肌症、子宫肌瘤[1,2].治疗CPP通常是有创伤性的甚至需要手术.CPP的治疗有... 详细信息

引言引起慢性盆腔痛(chronic pelvic pain,CPP)的妇科疾病包括盆腔粘连、附件包块、子宫内膜异位症、输卵管炎、残余卵巢综合征、盆腔淤血综合征、盆腔炎、子宫腺肌症、子宫肌瘤[1,2].治疗CPP通常是有创伤性的甚至需要手术.CPP的治疗有40%采用了腔镜,10%～12%切除了全子宫,这大大增加医疗费用[3,4].

关键词：子宫内膜异位症慢性盆腔痛间质性膀胱炎腹腔镜残余卵巢综合征盆腔淤血综合征子宫腺肌症盆腔粘连

视锥细胞营养不良和Stargardt’s病多焦视网膜电图潜伏期的差异

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眼视光学杂志 2003年第3期5卷 129-132页

作者：余敏忠吴经纬 RajK.Maturi 卫生部眼科学实验室中山大学眼科中心 Methodist Research Institute Indiana University Purdue University Indianapolis midwest Eye Institute IndianapolisIndianaUSA

目的:观察视锥细胞营养不良和Stargardt's病多焦视网膜电图潜伏期的差异。方法:用Verts Ⅳ系统记录分析4例视锥细胞营养不良、4例Stargardt's病和17例正常对照眼的多焦视网膜电图。将两组患者的结果分别与其年龄匹配的正常对照组的结果... 详细信息

目的:观察视锥细胞营养不良和Stargardt's病多焦视网膜电图潜伏期的差异。方法:用Verts Ⅳ系统记录分析4例视锥细胞营养不良、4例Stargardt's病和17例正常对照眼的多焦视网膜电图。将两组患者的结果分别与其年龄匹配的正常对照组的结果进行比较。结果:与正常对照组的结果比较,两组患者的多焦视网膜电图的反应密度在1～6环均有显著性下降。两组患者的反应密度在视野中央是较明显下降,随离心度增加反应密度逐渐趋近正常对照范围。视锥细胞营养不良组的潜伏期在1～3环和5～6环比正常对照组延长,但只有5～6环的数据与正常对照组差异有显著性。Stargardt's病组的潜伏期在视野中央比正常对照组延长,但只有3～4环的数据差异有显著性。结论:在较大离心度的视野部位,视锥细胞营养不良组的潜伏期比Stargardt's病组的潜伏期长,因此多焦视网膜电图的潜伏期有可能作为鉴别这两种遗传性眼底病的指标之一。

关键词：视锥细胞营养不良 Stargardt’s病多焦视网膜电图诊断鉴别诊断

腹腔镜Burch手术与经阴道尿道中段无张力悬吊带术治疗肥胖患者压力性尿失禁

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中国微创外科杂志 2005年第3期5卷 175-177页

作者：赵群段华 Maurice K.Chuang 首都医科大学附属北京妇产医院妇产科北京100006 首都医科大学附属北京复兴医院宫腔镜中心北京100038 midwest

在美国,超过250万的妇女受尿失禁的困扰[1].目前,治疗尿失禁的手术方法多达100种以上,但最常用的手术方法是耻骨阴道悬吊和耻骨后尿道悬吊,如MMK(Marshall-Marchetti-Krantz)--膀胱颈耻骨后悬吊术和Burch--尿道旁筋膜Cooper韧带悬吊术.... 详细信息

在美国,超过250万的妇女受尿失禁的困扰[1].目前,治疗尿失禁的手术方法多达100种以上,但最常用的手术方法是耻骨阴道悬吊和耻骨后尿道悬吊,如MMK(Marshall-Marchetti-Krantz)--膀胱颈耻骨后悬吊术和Burch--尿道旁筋膜Cooper韧带悬吊术.总的来说,手术成功率在80%以上,可以经开腹或在腹腔镜下完成[2～4].对肥胖患者而言,肥胖本身不仅增加腹腔镜手术并发症的发生率,而且增加手术失败的风险.相关研究[5～10]认为,肥胖因素一方面是压力性尿失禁的起因,同时也能导致尿失禁手术失败的几率增加.

关键词：治疗尿道悬吊术腹腔镜肥胖患者耻骨后经阴道压力性尿失禁无张力手术

Diagnostic role of fractional exhaled nitric oxide in pediatric eosinophilic esophagitis, relationship with gastric and duodenal eosinophils

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World Journal of Gastrointestinal Endoscopy 2023年第5期15卷 407-419页

作者： Panamdeep Kaur Rachel Chevalier Craig Friesen Jamie Ryan Ashley Sherman Stephanie Page Department of Pediatric Gastroenterology Connecticut Children’s Medical CenterUniversity of Connecticut School of MedicineHartfordConnecticutCT 06106United States Department of Pediatric Gastroenterology Children's Mercy Kansas CityUniversity of Missouri-Kansas City School of MedicineKansas CityMissouriMO 64108United States Department of Pediatrics University of Kansas School of MedicineKansas CityKansasKS 66160United States Department of Biostatistics Children's Mercy Kansas CityKansas CityMissouriMO 64108United States Department of Pediatric Gastroenterology Midwest Pediatric SpecialistsOverland ParkKansasKS 66215United States

BACKGROUND Eosinophilic esophagitis(EoE)is an eosinophilic-predominant inflammation of the esophagus diagnosed by upper endoscopy and biopsies.A non-invasive and cost-effective alternative for management of EoE is being *** studies assessing utility of fractional exhaled nitric oxide(FeNO)in EoE were low *** investigated the contribution of eosinophilic inflammation of the stomach and duodenum to *** To assess the utility of FeNO as a non-invasive biomarker of esophageal eosinophilic inflammation for monitoring disease *** Patients aged 6-21 years undergoing scheduled upper endoscopy with biopsy for suspected EoE were recruited in our observational *** on steroids and with persistent asthma requiring daily controller medication were *** measurements were obtained in duplicate using a chemiluminescence nitric oxide analyzer(NIOX MINO,Aerocrine,Inc.;Stockholm,Sweden)prior to *** on the esophageal peak eosinophil count(PEC)/high power field on biopsy,patients were classified as EoE(PEC≥15)or control(PEC≤14).Mean FeNO levels were correlated with presence or absence of EoE,eosinophil counts on esophageal biopsy,and abnormal downstream eosinophilia in the stomach(PEC≥10)and duodenum(PEC≥20).Wilcoxon rank-sum test,Spearman correlation,and logistic regression were used for analysis.P value<0.05 was considered *** We recruited a total of 134 patients,of which 45 were diagnosed with EoE by *** median interquartile range FeNO level was 17 parts per billion(11-37,range:7-81)in the EoE group and 12 parts per billion(8-19,range:5-71)in the control *** adjusting for atopic diseases,EoE patients had significantly higher FeNO levels as compared to patients without EoE(Z=3.33,P<0.001).A weak yet statistically significant positive association was found between the number of esophageal eosinophils and FeNO levels(r=0.30,P<0.005).On subgroup analysis within the EoE cohort,h

关键词： Nitric oxide Fractional exhaled nitric oxide Eosinophilic esophagitis Esophagus Pediatric Gastroenterology

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胺碘酮导致的视神经病

世界核心医学期刊文摘（眼科学分册） 2006年第10期2卷 12-12页

作者： Purvin V. Kawasaki A. Borruat F.-X. 王永强 midwest Eye Institute 201 Pennsylvania PkwyIndianapolisIN 46280United States Dr.

Objective:To refine the criteria for the diagnosis of amiodarone-related optic neuropathy by including a broader spectrum of clinical features,thus helping to differentiate this entity from nonarteritic anterior ischemic optic neuropathy coincidentally affecting a patient taking ***:A retrospective case review of 22 patients who developed optic neuropathy while taking amiodarone,in whom other systemic causes were ***:We identified 3 groups of patients:those in whom a diagnosis of amiodarone-induced optic neuropathy seems probable(n=14),those in whom an association with amiodarone optic neuropathy is indeterminate(n=5),and those in whom the occurrence of nonarteritic anterior ischemic optic neuropathy seems to be coincidental(ie,unrelated to amiodarone)(n=3).We formulated specific diagnostic criteria for each of these ***:We recommend a systematic approach that includes assessment of bilaterality,mode of onset,degree of optic nerve dysfunction,structure of the uninvolved optic disc in unilateral cases,and systemic toxic *** well-defined diagnostic criteria can help the clinician in the treatment of patients with this disorder.

关键词：发作形式神经功能异常诊断标准动脉炎全身毒性组织结构处理方法

Impact of a physical activity program on plasma concentrations of adiponectin, leptin and ghrelin in overweight and obese schoolchildren: A randomized controlled trial

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Health 2013年第11期5卷 1819-1828页

作者： Andre Everton de Freitas Joel Alves Lamounier Danusa Dias Soares Thiago Henrique de Oliveira Debora Romualdo Lacerda Joyce Batista Andrade Flavia Komatsuzaki Leida Maria Botion Adaliene Versiani Matos Ferreira Camilo Adalto Mariano da Silva Dilermando Fazito Rezende Graduate Program in Child and Teenager Health Medicine SchoolFederal University of Minas GeraisBelo HorizonteBrazil Faculty of Health and Human Ecology Medicine SchoolVespasianoBrazil Graduate Program in Health Sciences Medicine SchoolFederal University of Sao Joao Del ReiCampus MidwestDivinopolisBrazil Laboratory of Exercise Physiology Federal University of Minas GeraisBelo HorizonteBrazil Laboratory of Metabolism Federal University of Minas GeraisBelo HorizonteBrazil School of Nursing Federal University of Minas GeraisBelo HorizonteBrazil School of Nutrition Federal University of Ouro PretoOuro PretoBrazil Faculty of Medicine Barbacena BarbacenaBrazil

Introduction: Child obesity has important consequences on the child’s health and is related to the risk of developing chronic diseases. That brings up the need for research assessing the impact of obesity-and overweight-reduction programs with close attention to methodology aspects and precise indicators of the impact of such programs. Goal: Assessing the impact of a physical activity program on the plasma concentrations of adiponectin, leptin, and ghrelin in overweight and obese schoolchildren. Methods: Randomized controlled trial, double-blind, with 6-to 9-year-old overweight and obese school-children. A sample of 79 schoolchildren randomly distributed into control and intervention groups was subjected to a physical activity program. The levels of adiponectin, leptin, ghrelin, body mass index, body fat percentage, anthropometry, lipid profile and glycemia were evaluated. The program’s impact was assessed through multivariate linear regression models. Result: When comparing the groups, a significant difference was found for adiponectin, which shows an increase in the proportion of subjects with higher adiponectin concentrations for the intervention group and a reduction in body mass index and body fat percentage. Conclusion: The impact of the intervention program was positive in increasing adiponectin levels associated with a reduction in body mass index and body fat percentage.

关键词： Obesity Overweight Schoolchildren Physical Activity Adipocitokines

Differential Etiology of Posttraumatic Stress Disorder with Conduct Disorder and Major Depression in Men

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Differential Etiology of Posttraumatic Stress Disorder with ...

Global concerns related to water biology and security:The need for language and policies that safeguard living resources versus those that dilute scientific knowledge

北京论坛（2006）文明的和谐与共同繁荣—对人类文明方式的思考

作者： Karestan C.Koenen Mark W.Miller Andrew C.Heath Kathleen K.Bucholz Michael J.Lyons Seth A.Eisen William R.True Jack Goldberg Ming T.Tsuang Department of Society Human Developmentand HealthHarvard School of Public HealthBostonMA Department of Psychiatry Boston University School of Medicine midwest Alcoholism Research Center at Washington University Department of Psychiatry Washington University School of MedicineSt.LouisMO Department of Psychology Boston UniversityBostonMA Harvard Institute of Psychiatric Epidemiology and Genetics Department of EpidemiologyHarvard School of Public HealthBostonMA Department of Psychiatry Harvard Medical School at MassachusettsMental Health CenterBostonMA Department of Internal Medicine Washington University School of MedicineSt.LouisMO Department of Community Health St.Louis University School of Public HealthSt.LouisMO Seattle VA ERIC/Vietnam Era Twin Registry SeattleWashington Department of Epidemiology University of WashingtonSeattleWashington University of California Medical School in San Diego San DiegoCA

Posttraumatic stress disorder(PTSD) is a notable public health *** is an extremely debilitating condition that can occur following exposure to a psychologically distressing event that is outside the range of usual human *** events that can trigger PTSD include violent personal assaults(*** and sexual abuse),natural or human-caused disasters(*** and terrorism bombing),accidents(*** traffic accidents and families of victims),or military *** etiology of PTSD is not clear, although exposure to a traumatic event constitutes a necessary,but not sufficient,*** is highly comorbid with major depression(MD) and conduct disorder(CD) in both epidemiologic and clinical *** of individuals who are at elevated risk for developing PTSD has important implications for public health disaster preparedness and prevention of *** examine the genetic and environmental architecture of the comorbidity of PTSD with MD and CD,we analyzed 6,744 middle aged male-male monozygotic and dizygotic twins from the Vietnam Era Twin Registry maintained in the *** members of a pair were interviewed by telephone using the Diagnostic Interview Schedule for Diagnostic and Statistical Manual of Mental Disorders,Third Edition,Revised(DSM-Ⅲ-R) in *** equation modeling was used to estimate additive genetic,shared environmental and nonshared environmental effects common and specific to PTSD,CD,and MD.A set of competing nested models were assessed by comparing the goodness-of-fit between the full model and the submodel using the chi-square test and *** found that genetic,shared environmental and nonshared environmental influences contributed to 19%(95%CI:11-26%),9%(95%CI:6-17%), and 70%(95%CI:64-77%) of the total variance in PTSD,*** genetic effects on PTSD overlapped with those on MD,while all shared environmental effects on PTSD overlapped with those on *** 3%and 8%of nonshared env

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cnki会议

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Water Biology and Security 2023年第4期2卷 136-146页

作者： Robert M.Hughes James R.Karr Robert L.Vadas Dominick A.DellaSala Marcos Callisto Maria Joao Feio Teresa Ferreira Neels Kleynhans Renata Ruaro Chris O.Yoder J.Hal Michael Amnis Opes Institute 2895 SE GlennCorvallisOR97333USA Department of Fisheries Wildlife&Conservation SciencesOregon State UniversityCorvallisOR97331USA School of Aquatic and Fishery Sciences University of WashingtonSeattleWA98915USA Karr Consulting 102 Galaxy View CourtSequimWA98382USA 2909 Boulevard Rd.SE OlympiaWA98501-3971USA Wild Heritage a Project of Earth Island Institute2150 Allston WayBerkeleyCA94704-1346USA Departamento de Genetica Ecologia e EvolucaoInstituto de Ciencias BiologicasUniversidade Federal de Minas GeraisAvenida Antonio Carlos 6627CEP 31270-901Belo HorizonteMGBrazil Associate Laboratory ARNET Marine and Environmental Sciences CentreDepartment of Life SciencesUniversity of CoimbraCoimbraPortugal Forest Research Centre&Associate Laboratory TERRA University of LisbonTapada da Ajuda1349-017LisbonPortugal Department of Water Affairs and Forestry(retired) 8th Avenue 771Wonderboom South0084PretoriaSouth Africa Graduate Program in Environmental Science and Technology Federal Technological University of Parana81280-340CuritibaPRBrazil midwest Biodiversity Institute 4673 Northwest ParkwayHilliardOH43026USA Ecologists Without Borders OlympiaWAUSA

Increasingly,scientists and non-scientists,especially employees of government agencies,tend to use weak or equivocal language when making statements related to science policy and governmental *** use recent publications to provide examples of vague language versus examples of strong language when authors write about regulating anthropogenic pressures on natural *** language is common in agency reports,policy documents,and even scientific papers published by *** language limits success in regulating anthropogenic pressures on natural *** challenge must be recognized and countered as a driver of the condition of water and associated *** also list sources of vague wording,provide global examples of how ambiguous language and political influences have contributed to water resource degradation,discuss the recent history of science censorship,and offer possible solutions for more direct scientific *** found that:(1)equivocal language was especially common in concluding statements and not only by government employees;(2)authors discussed confusing language concerns in an agency publication;and(3)agency employees sometimes used active,strong *** drivers of weak language include:(1)holding on to old paradigms and resisting new knowledge;(2)scientific uncertainty;(3)institutional manuscript review policies;(4)employment and funding insecurity;and(5)avoiding the appearance of *** associated with euphemistic language included climate change,flow and physical habitat alteration,dams,agriculture,mining,forestry,and fisheries,as well as resistance towards monitoring,assessing,and reporting ecological *** for mitigating equivocal language involve employment protections and greater focus on scientific *** conclude that natural resource scientists should resist calls to employ imprecise ***,they should be strong advocates for prescriptive and protective natura

关键词： Corruption Ethics Science censoring Science policy Water resource degradation

Assemblage-based biomonitoring of freshwater ecosystem health via multimetric indices:A critical review and suggestions for improving their applicability

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Water Biology and Security 2022年第3期1卷 28-42页

作者： Robert L.Vadas Jr. Robert M.Hughes Yeon Jae Bae Min Jeong Baek Orestes Carlos Bello Gonzáles Marcos Callisto Débora ReisdeCarvalho Kai Chen Maria T.Ferreira Pablo Fierro Jon S.Harding Dana M.Infante C.J.Kleynhans Diego R.Macedo Isabela Martins Norman Mercado Silva Nabor Moya Susan J.Nichols Paulo S.Pompeu Renata Ruaro Deborah R.O.Silva R.Jan Stevenson Bianca de Freitas Terra Christa Thirion Douglas Ticiani Lizhu Wang Chris O.Yoder 2909 Boulevard Rd SEOlympiaWA98501-3971USA Amnis Opes Institute 2895 SE GlennCorvallisOR97333USA Department of Fisheries Wildlife&Conservation SciencesOregon State UniversityCorvallisOR97331USA Division of Environmental Science&Ecological Engineering Korea University145 Anam-roSeongbuk-guSeoul02841South Korea National Institute of Biological Resources Ministry of Environment42 Hwangyeong-roSeo-guIncheon22689South Korea Centro de Investigacion en Biodiversidad y Conservacion Universidad Autonoma del Estado de Morelos1001Col.ChamilpaC.P62209CuernavacaMorelosMexico Departamento de Genética Ecologia e EvoluçaoInstituto de Ciências BiologicaUniversidade Federal de Minas GeraisAvenida Ant^onio Carlos 6627CEP31270-901Belo HorizonteMGBrazil Departamento de Ecologia e Conservaçao Universidade Federal de Lavras37200-900LavrasMGBrazil State Key Laboratory of Marine Resource Utiliization in South China Sea Hainan UniversityHaikou570228China Forest Research Centre&Associate Laboratory TERRA University of LisbonTapada da Ajuda1349-017LisbonPortugal Instituto de Ciencias Marinas y Limnologicas Universidad Austral de ChileValdiviaChile School of Biological Sciences University of CanterburyPrivate Bag 4800Christchurch8140New Zealand Department of Fisheries&Wildlife Michigan State University1405 South Harrison Road#318East LansingMI48823USA Department of Water Affairs and Forestry(retired) 8th Avenue 771Wonderboom South0084PretoriaSouth Africa Departamento de Geografia Instituto de GeociênciasUniversidade Federal de Minas GeraisAvenida Antônio Carlos 6627CEP31270-901Belo HorizonteMGBrazil Instituto Guaicuy 109 Rua BrasopolisBelo HorizonteMG31150-170Brazil Centro de Investigación en Biodiversidad y Conservación Universidad Autónoma del Estado de MorelosAvenida Universidad 1001Col.ChamilpaC.P.62209CuernavacaMorelosMexico Instituto Experimental de Biología Universidad San Francisco Xavier de ChuquisacaSucreBolivia Centre for Applied Water Science Un

Freshwater biota are more comprehensive and direct indicators of biological impacts,and more meaningful to the public than water quality or physical habitat *** biotic data and the multiple biological indicators developed from them offer a much richer array of data for assessing the impacts of pollution controls than a limited set of physical or chemical *** recent decades,assemblage-based assessments by ecologists,environmental scientists,and water quality agencies have been employed globally for determining the condition of,and threats to,freshwater ecosystems.A key step in this advance has been the development of multimetric indices(MMIs)or indices of biotic integrity(IBIs)based on quantitative assessments of algae,macrophyte,macroinvertebrate,fish or riparian bird *** Europe,where biological assemblages are mandated for assessing freshwater ecosystem health,many indices are ***,the proliferation of MMIs globally has not always occurred through the application of rigorous study designs and monitoring protocols,nor have they always effectively incorporated functional metrics,stressor assessments,and statistical ***,in this review,we discuss eleven major concerns with the development and application(including logistical limitations)of multimetric indicators based on freshwater biota to encourage more rigorous and widely applicable(transferable)MMI use and ***,our concerns focus on reference conditions;sampling effort,methods,and season;trophic guild definition;metric comprehensiveness,options,screening and scoring;and MMI *** could also benefit from increased attention to ecological mechanisms and metric development,to further improve our understanding of anthropogenic impacts as well as rehabilitation effects on freshwater ecosystems *** closer attention to study designs,ecological mechanisms and metric development should further improve our understa

关键词： IBI MMI Fish Macroinvertebrates Algae Streams Rivers Lakes Wetlands Biological monitoring