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Microengineered platforms for characterizing the contractile function of in vitro cardiac models

Microsystems & Nanoengineering 2022年第1期8卷 29-50页

作者： Wenkun Dou Manpreet Malhi Qili Zhao Li Wang Zongjie Huang Junhui Law Na Liu Craig A.Simmons Jason T.Maynes Yu Sun Department of Mechanical and Industrial Engineering University of TorontoTorontoON M5S 3G8Canada Program in Molecular Medicine The Hospital for Sick ChildrenTorontoON M5G 1X8Canada Department of Biochemistry University of TorontoTorontoON M5S 1A8Canada Institute of Robotics and Automatic Information System and the Tianjin Key Laboratory of Intelligent Robotics Nankai UniversityTianjin 300350China School of Mechanical&Automotive Engineering Qilu University of Technology(Shandong Academy of Sciences)Jinan 250353China School of mechatronics Engineering and Automation Shanghai UniversityShanghai 200444China Institute of Biomedical Engineering University of TorontoTorontoON M5S 3G9Canada Translational Biology&Engineering Program Ted Rogers Centre for Heart ResearchTorontoON M5G 1M1Canada Department of Anesthesiology and Pain Medicine University of TorontoTorontoON M5S 1A8Canada Department of Anesthesia and Pain Medicine The Hospital for Sick ChildrenTorontoON M5G 1X8Canada Department of Electrical and Computer Engineering University of TorontoTorontoON M5S 3G4Canada Department of Computer Science University of TorontoTorontoON M5T 3A1Canada

Emerging heart-on-a-chip platforms are promising approaches to establish cardiac cell/tissue models in vitro for research on cardiac physiology,disease modeling and drug cardiotoxicity as well as for therapeutic *** still exist in obtaining the complete capability of in situ sensing to fully evaluate the complex functional properties of cardiac cell/tissue *** to contractile strength(contractility)and beating regularity(rhythm)are particularly important to generate accurate,predictive *** new platforms and technologies to assess the contractile functions of in vitro cardiac models is essential to provide information on cell/tissue physiologies,drug-induced inotropic responses,and the mechanisms of cardiac *** this review,we discuss recent advances in biosensing platforms for the measurement of contractile functions of in vitro cardiac models,including single cardiomyocytes,2D monolayers of cardiomyocytes,and 3D cardiac *** characteristics and performance of current platforms are reviewed in terms of sensing principles,measured parameters,performance,cell sources,cell/tissue model configurations,advantages,and *** addition,we highlight applications of these platforms and relevant discoveries in fundamental investigations,drug testing,and disease ***,challenges and future outlooks of heart-on-a-chip platforms for in vitro measurement of cardiac functional properties are discussed.

关键词： cardiac contractile regularity

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Preface

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Journal of Bionic Engineering 2019年第3期16卷 I0001-I0002页

作者： Marco Ceccarelli Giuseppe Carbone Laboratory of Robot mechatronics Dept of Industrial Engineering University of Rome Tor Vergata Via del Politecnico 1 00133 Roma Italy Universita della Calabria DIMEG Via Bucci Cubo 46C 87036 Rende (Cs) Italy

Medical and Service Robotics are getting a growing market and an increasing interest from both research and applications viewpoints. Indeed, the aging of population and shortage of resources is widening the need of novel robotic solutions and devices in a wide range of novel applications. For example, assistance devices for medical treatments and rehabilitation are attracting significant interest with several laboratory and even commercial solutions. Human-Robot interactions and performance evaluations attract growing interest to validate the effectiveness and acceptability of the proposed solutions.

关键词： Medical Service solutions

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薄膜分光钙钛矿光伏/光热太阳能利用器件

薄膜分光钙钛矿光伏/光热太阳能利用器件

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第六届新型太阳能电池材料科学与技术学术研讨会

作者：高宇张衍国杨潇潇丛堃林谭中超李清海清华大学能源与动力工程系热科学与动力工程教育部重点实验室清华大学-滑铁卢大学微纳米能源环境联合研究中心 Department of Mechanical & mechatronics Engineering University of Waterloo

新兴的钙钛矿电池具有活性层便宜、适合大面积生产等优点,近几年受到广泛关注。但目前钙钛矿太阳能电池的研究多以提高局部光谱的能量利用效率为主,缺乏站在热物理的角度综合考虑全局能量的视角。在太阳光谱中,红外区占据43%的能量,却... 详细信息

新兴的钙钛矿电池具有活性层便宜、适合大面积生产等优点,近几年受到广泛关注。但目前钙钛矿太阳能电池的研究多以提高局部光谱的能量利用效率为主,缺乏站在热物理的角度综合考虑全局能量的视角。在太阳光谱中,红外区占据43%的能量,却无法被光伏电池吸收,且会使电池温度上升导致效率下降,造成能量损失。因此,我们提出一种新的太阳能利用思路——一种基于新兴钙钛矿的半导体薄膜分光复合太阳能光伏/光热利用器件:通过反射膜将入射太阳光分解为有利于光伏和光热利用的"并联"的两束不同波长光束,光伏部分由钙钛矿太阳能电池利用,光热部分通过汇聚反射输出热能或进行发电。在提高光谱利用率的同时,反射红外辐射可降低太阳电池工作温度,避免电池温度负效应导致的光伏效率下降。最终太阳能的热能/电能综合利用效率可超60%,单纯发电效率可超35%。红外反射膜在灯具、建筑市场中已有研究与应用基础,具备良好的透过可见光、反射红外光的功能。未来研究内容包括:跟踪国内外先进研究成果,学习钙钛矿太阳能电池的制备方法,并探索改进,掌握适用于该复合系统的电池制备方法;通过滤光片,研究钙钛矿电池在剔除红外辐射后的光伏性能变化,并与常规太阳能电池对比;制备带多层介质红外反射膜的钙钛矿太阳电池,并对电池性能进行评估;以实验为基础,开发光量子热/电效率集成模型。本研究创新性地提出了将热物理、半导体物理和薄膜光学相结合的太阳能综合利用分析方法,对提高太阳能利用效率具有重要意义。

关键词：钙钛矿太阳能电池薄膜分光太阳能综合利用

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Bio-Fabrication of Silver Nanoparticles Using Catha edulis Extract: Procedure Optimization and Antimicrobial Efficacy Encountering Antibiotic-Resistant Pathogens

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Advances in Nanoparticles 2022年第2期11卷 31-54页

作者： Abdulqawi A. Numan Mashhour Ahmed Mansour S. A. Galil Mohyeddine Al-Qubati Ayman A. Raweh Enas A. Helmi Department of Chemistry Faculty of Applied Sciences Taiz University Taiz Yemen Department of Pharmacy Faculty of Medical Sciences Al-Janad University for Science and Technology Taiz Yemen. Department of Pharmaceutical Chemistry and Natural Products University of Science and Technology (UST) Sana’a Yemen Central for Research and Pharmaceutical Studies (CRPS) University of Science and Technology (UST) Sana’a Yemen Department of mechatronics Faculty of Engineering and Information Technology Al-Janad University for Science and Technology Taiz Yemen Department of Physics Faculty of Applied Sciences Taiz University Taiz Yemen Department of Microbiology Faculty of Applied Sciences Taiz University Taiz Yemen Department of Clinical Laboratory Faculty of Medical Sciences Al-Janad University for Science and Technology Taiz Yemen

The current study aimed to optimize a green synthesis procedure for fabricating biogenic silver nanoparticles (AgNPs) using an aqueous extract of Catha edulis (Qat;khat) leaves. The final product was characterized using various analytical techniques. Parameters’ optimization including pH, contact time, temperature, and amount of leaf extract were carried out. AgNPs formation was confirmed by UV-vis spectra at 403 nm, FT-IR, and XRD peaks. FTIR spectra showed the presence of various biochemical metabolites which played a critical role in the bio-reduction, capping, and stabilization of AgNPs. The biogenic AgNPs were spherical in shape with an average size between 27 and 32 nm as estimated from XRD and SEM images. Biogenic AgNPs showed significant activities against sensitive and multi-drug resistance Escherichia coli and Staphylococcus aureus strains. In addition, the experimental results proved that AgNPs have higher efficacy than antifungal drugs that are commonly used to treat Candida albicans oral infections.

关键词： Silver Nanoparticles Biosynthesis Catha edulis Candida albicans Antibacterial Activity

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Correction:2D MoS2 Helical Liquid Crystalline Fibers for Multifunctional Wearable Sensors

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Advanced Fiber Materials 2024年第6期6卷 1997-1997页

作者： Park, Jun Hyun Kim, Jang Hwan Lee, Su Eon Kim, Hyokyeong Lim, Heo Yeon Park, Ji Sung Yun, Taeyeong Lee, Jinyong Kim, Simon Jin, Ho Jun Park, Kyeong Jun Kang, Heemin Kim, Hoe Joon Jin, Hyeong Min Kim, Jiwoong Kim, Sang Ouk Kim, Bong Hoon Department of Robotics and mechatronics Engineering DGIST Daegu Republic of Korea Platform Technology R&D Center LG Chemistry Seoul Republic of Korea Department of Materials Science and Engineering National Creative Research Initiative Center for Multi-Dimensional Directed Nanoscale Assembly KAIST Institute for Nanocentury KAIST Daejeon Republic of Korea Department of Materials Science and Engineering Soongsil University Seoul Republic of Korea Department of Organic Materials Engineering Chungnam National University Daejeon Republic of Korea Department of Materials Science and Engineering Chungnam National University Daejeon Republic of Korea Nano Convergence Technology Research Center Korea Electronics Technology Institute (KETI) Gyeonggi-do Republic of Korea Department of Green Chemistry and Materials Engineering Soongsil University Seoul Republic of Korea Department of Materials Science and Engineering Korea University Seoul Republic of Korea

In the Acknowledgements section, the following sentence was missing. "This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (No. RS-2024-00406240). " Th...

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Fuzzy Based Auto-coagulation Control Through Photometric Dispersion Analyzer

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Journal of Harbin Institute of Technology(New Series) 2004年第2期11卷 164-167页

作者：白桦李圭白 School of Environmental Engineering Tongji UniversityShanghai 200092 China School of mechatronics Engineering Harbin Institute of Technology Harbin 150006 China 3. School of Municipal and Environmental Engineering Harbin Institute of Technology Harbin 150090 Chinahe main role of water treatment plants is to supply high-quality safe drinking water. Coagulation is one of the most important stages of surface water treatment. The photometric dispersion analyzer(PDA) is a new optical method for flocculation monitoring and is feasible to realize coagulation feedback control. The on line modification of the coagulation control system's set point(or optimum dosing coagulant) has influenced the application of this technology in water treatment plant for a long time. A fuzzy control system incorporating the photometric dispersion analyzer was utilized in this coagulation control system. Proposed is a fuzzy logic inference control system by using Takagi and Sugeno's fuzzy if-then rule for the self-correction of set point on line. Programmed is the dosing rate fuzzy control system in SIEMENS small-scale programmable logic controller. A 400 L/min middle-scale water treatment plant was utilized to simulate the reaction. With the changes of raw water qualitythe set point was modified correctly in time as well as coagulant dosing rate and residual turbility before filtration was eligible and stable. Results show that this fuzzy inference and control system performs well on the coagulation control system through PDA.

The main role of water treatment plants is to supply high-quality safe drinking water. Coagulation is one of the most important stages of surface water treatment. The photometric dispersion analyzer(PDA) is a new optical method for flocculation monitoring, and is feasible to realize coagulation feedback control. The on line modification of the coagulation control system' s set point( or optimum dosing coagulant) has influenced the application of this technology in water treatment plant for a long time. A fuzzy control system incorporating the photometric dispersion analyzer was utilized in this coagulation control system. Proposed is a fuzzy logic inference control system by using Takagi and Sugeno' s fuzzy if-then rule for the self-correction of set point on line. Programmed is the dosing rate fuzzy control system in SIEMENS small-scale programmable logic controller. A 400 L/min middle-scale water treatment plant was utilized to simulate the reaction. With the changes of raw water quality, the set point was modified correctly in time, as well as coagulant dosing rate, and residual turbility before filtration was eligible and stable. Results show that this fuzzy inference and control system performs well on the coagulation control system through PDA.

关键词： coagulation dosing rate control photometric dispersion analyzer fuzzy control fuzzy logic inference optimum water treatment

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Rabi antenna using microstrip add-drop multiplexer for electron warp speed investigation

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Chinese Optics Letters 2022年第7期20卷 80-87页

作者： Somchat Sonasang Prakasit Prabpal Piya Sirikan Pratimakorn Hakaew Nhat Truong Pham Preecha Yupapin Kanad Ray Sarawoot Boonkirdram Department of Electronic Technology Faculty of Industrial TechnologyNakhon Phanom UniversityNakhon Phanom 48000Thailand Department of Electrical Technology School of Industrial TechnologySakonnakhon Technical CollegeInstitute of Vocational Education Northeastern Region 2Sakonnakhorn 47000Thailand Division of Computational mechatronics Institute for Computational ScienceTon Duc Thang UniversityHo Chi Minh City 72915Vietnam Faculty of Electrical and Electronics Engineering Ton Duc Thang UniversityHo Chi Minh City 72915Vietnam Amity School of Applied Sciences Amity University RajasthanJaipurIndia Faubert Lab Universitéde MontréalH3T 1P1 MontréalCanada Facultad de CienciasFisico-Matematicas Benemérita Universidad Autónoma de PueblaAv.San Claudio y Av.18 surCol.San Manuel Ciudad UniversitariaPuebla Pue 72570Mexico Program of Electrical and Electronics Faculty of Industrial TechnologySakon Nakhon Rajabhat UniversitySakon Nakhon 47000Thailand

This work presents experimental results of Rabi antenna characteristics using the coupled line microstrip *** was constructed by a modified coupled line microstrip four-port network,which is known as an add-drop *** driven AC input enters the device via an input port using the suitable frequency and coupled line microstrip ring *** multilevel system is generated by a wave-particle aspect before the two-level system is *** the resonance,the transitions of the states induce the energy called whispering gallery mode(WGM)at the circuit center,which is the squeezed *** generated electron oscillation within the WGM envelope oscillated by the frequency is known as the Rabi *** the successive filtering with continuous AC input via the selected port,the electron cloud warp speed can be generated and achieved inside the two-level *** constructed microstrip ring radius is 25 mm,and the experimental results of the Rabi antenna characteristics are in good agreement with the simulation *** obtained resonant antenna oscillation frequency is 2.103 *** electron cloud warp speed of 1.100c and time dilation of 0.006μs are obtained.

关键词： integrated photonics waveguide microwave photonics Rabi antenna

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2011双喜临门

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液压气动与密封 2011年第1期31卷 I0002-I0002页

作者：李运华 <液压气动与密封> 北京航空航天大学自动化科学与电气工程学院中国机械工程学会流体传动与控制分会国际学术期刊IEEE/ASME Transactionson mechatronics

在2011年新年伊始，我们迎来了《液压气动与密封》杂志创刊30周年，可谓“双喜临门”。值新春和30年刊庆之际，我特向杂志读、作者和行业的朋友们致以新春的问候和崇高的敬意!

关键词：《液压气动与密封》 2011年期刊改革开放

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