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Multimorbidity and mortality among older patients with coronary heart disease in Shenzhen,China

Journal of Geriatric Cardiology 2024年第1期21卷 81-89页

作者： Fu-Rong LI Shuang WANG Xia LI Zhi-Yuan CHENG Cheng JIN Chun-Bao MO Jing ZHENG Feng-Chao LIANG Dong-Feng GU Shenzhen Key Laboratory of Cardiovascular health and Precision Medicine Southern University of Science and TechnologyShenzhenGuangdongChina School of Public health and Emergency management Southern University of Science and TechnologyShenzhenGuangdongChina Shenzhen health Development Research and Data management Center ShenzhenChina School of Medicine Southern University of Science and TechnologyShenzhenGuangdongChina

BACKGROUND The current understanding of the magnitude and consequences of multimorbidity in Chinese older adults with coronary heart disease(CHD)is *** aimed to assess the association and population-attributable fractions(PAFs)between multimorbidity and mortality among hospitalized older patients who were diagnosed with CHD in Shenzhen,*** We conducted a retrospective cohort study of older Chinese patients(aged≥65 years)who were diagnosed with *** proportional hazards models were used to estimate the associations between multimorbidity and all-cause and cardiovascular disease(CVD)*** also calculated the *** The study comprised 76,455 older hospitalized patients who were diagnosed with CHD between January 1,2016,and August 31,*** them,70,217(91.9%)had multimorbidity,defined as the presence of at least one of the predefined 14 chronic *** with cancer,hemorrhagic stroke and chronic liver disease had the worst overall death risk,with adjusted HRs(95%CIs)of 4.05(3.77,4.38),2.22(1.94,2.53),and 1.85(1.63,2.11),*** CVD mortality,the highest risk was observed for hemorrhagic stroke,ischemic stroke,and chronic kidney disease;the corresponding adjusted HRs(95%CIs)were 3.24(2.77,3.79),1.91(1.79,2.04),and 1.81(1.64,1.99),***-cause mortality was mostly attributable to cancer,heart failure and ischemic stroke,with PAFs of 11.8,10.2,and 9.1,*** for CVD mortality,the leading PAFs were heart failure,ischemic stroke and diabetes;the corresponding PAFs were 18.0,15.7,and 6.1,*** Multimorbidity was common and had a significant impact on mortality among older patients with CHD in Shenzhen,***,heart failure,ischemic stroke and diabetes are the primary contributors to ***,prioritizing improved treatment and management of these comorbidities is essential for the survival prognosis of CHD patients from a holistic public health perspective.

关键词： patients morbidity mortality

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Comparison of toxicity between lanthanum oxide nanoparticles and lanthanum chloride

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Journal of Rare Earths 2024年第2期42卷 424-430,I0007页

作者： Kun Huang Songchang Lai Miao Guo Xingwu Zhu Jiashuangwei Yuan Zhehao Liu Gonghua Hu Yanfang Gao School of Public health and health management Gannan Medical UniversityGanzhou341000China

Due to the wide application of rare earth elements,lanthanum(La) is gradually accumulated in our living *** can enter the body through a variety of routes,which has a series of effects on various *** a consequence,the safety of lanthanum deserves our *** study aims to compare the toxicity of lanthanum oxide nanoparticles(La_(2)O_(3) NPs) and lanthanum chloride(LaCl_(3)) and enrich the toxicity evaluation of ***,a 30 d intragastal experiment was conducted.C57BL/6j mice were given by La_(2)O_(3) NPs solution and LaCl_(3) solution respectively at doses of 0,30,60 and120 mg/kg BW(lanthanum content).The results show that,compared with the control group,both La_(2)O_(3)NPs and LaCl_(3) can reduce the body weight of female mice in the high-dose group,but for male mice,the high-dose La_(2)O_(3) NPs solution can increase the body weight,while LaCl_(3) has the opposite *** coefficients of liver,kidney,heart,lung,uterine and ovaries increase first and then decrease with the exposure dose,but testes and epididymides coefficient keep increasing with the exposure of LaCl_(3) and La_(2)O_(3) ***_(2)O_(3) NPs and LaCl_(3) can reduce the concentration of triglycerides(TG) and increase the level of low density lipoprotein(LDL),but the effect of La_(2)O_(3) NPs is more ***_(2)O_(3) NPs and LaCl_(3) can reduce the concentration of malondialdehyde(MDA),increase the total antioxidant capacity(T-AOC)and enhance the activity of catalase(CAT),but LaCl_(3) has more obvious protective effects on oxidative ***_(2)O_(3) NPs and LaCl_(3) have potential risks to liver,and the toxicity of La_(2)O_(3) NPs might be higher than that of LaCl_(3).

关键词： Rare earth elements Lanthanum oxide nanoparticles Lanthanum chloride Lipid metabolism Oxidative stress

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Exploring the Lagged Correlation Between Baidu Index and Influenza-Like Illness-China,2014-2019

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China CDC weekly 2024年第26期6卷 629-634页

作者： Xuan Han Jiao Yang Yan Luo Dazhu Huo Xuya Yu Xuancheng Hu Ling Xin Liuyang Yang Hualei Xin Ting Zhang Zhongjie Li Weizhong Yang School of Population Medicine and Public health Chinese Academy of Medical Sciences(CAMS)&Peking Union Medical CollegeBeijingChina School of health Policy and management Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijingChina Department of management science and information system Faculty of Management and EconomicsKunming University of Science and TechnologyKunming CityYunnan ProvinceChina

Introduction:This study investigated the lagged correlation between Baidu Index for influenza-related keywords and influenza-like illness percentage(ILI%)across regions in *** aim is to establish a scientific foundation for utilizing Baidu Index as an early warning tool for influenza-like illness ***:In this study,data on ILI%and Baidu Index were collected from 30 provincial-level administrative divisions(PLADs)spanning April 2014 to March *** Baidu Index was categorized into Overall Index,Ordinary Index,Prevention Index,Symptom Index,and Treatment Index based on search query *** lagged correlation between the Baidu Index and ILI%was examined through the cross-correlation function(CCF)***:Correlating the Baidu Overall Index of 30 PLADs with ILI%revealed CCF values ranging from 0.46 to 0.86,with a median lag of 0.5 *** analysis indicated that the Prevention Index and Symptom Index exhibited quicker responses to ILI%,with median lags of−9 and−0.5 days,respectively,compared to 0 and 3 days for the Ordinary and Treatment *** median lag days between the Baidu Index and the ILI%were earlier in the northern PLADs compared to the southern ***:The Prevention and Symptom Indexes show promising predictive capabilities for influenzalike illness epidemics.

关键词： utilizing illness Baidu

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Toward Human-centered XAIin Practice:A survey

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Machine Intelligence Research 2024年第4期21卷 740-770页

作者： Xiangwei Kong Shujie Liu Luhao Zhu Department of Data science and management Engineering School of ManagementZhejiang UniversityHangzhou 310058China

Human adoption of artificial intelligence(AI)technique is largely hampered because of the increasing complexity and opacity of AI *** AI(XAI)techniques with various methods and tools have been developed to bridge this gap between high-performance black-box AI models and human ***,the current adoption of XAI technique stil lacks"human-centered"guidance for designing proper solutions to meet different stakeholders'needs in XAI *** first summarize a human-centered demand framework to categorize different stakeholders into five key roles with specific demands by reviewing existing research and then extract six commonly used human-centered XAI evaluation measures which are helpful for validating the effect of *** addition,a taxonomy of XAI methods is developed for visual computing with analysis of method *** clearer human demands and XAI methods in mind,we take a medical image diagnosis scenario as an example to present an overview of how extant XAI approaches for visual computing fulfil stakeholders'human-centered demands in *** we check the availability of open-source XAI tools for stakeholders'*** survey provides further guidance for matching diverse human demands with appropriate XAI methods or tools in specific applications with a summary of main challenges and future work toward human-centered XAI in practice.

关键词： Artificial intelligence(AI)application explainable AI(XAI) human-centered design visual computing medical diagnosis.

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Dynamics of information diffusion and disease transmission in time-varying multiplex networks with asymmetric activity levels

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Chinese Physics B 2024年第3期33卷 690-699页

作者：谢笑笑霍良安董雅芳程英英 Business School University of Shanghai for Science and TechnologyShanghai 200093China School of Intelligent Emergency management University of Shanghai for Science and TechnologyShanghai 200093China School of management Henan University of Science and TechnologyLuoyang 471023China

While the interaction between information and disease in static networks has been extensively investigated,many studies have ignored the characteristics of network *** this study,we construct a new two-layer coupling model to explore the interactions between information and *** upper layer describes the diffusion of disease-related information,and the lower layer represents the disease *** then use power-law distributions to examine the influence of asymmetric activity levels on dynamic propagation,revealing a mapping relationship characterizing the interconnected propagation of information and diseases among partial nodes within the ***,we derive the disease outbreak threshold by using the microscopic Markov-chain approach(MMCA).Finally,we perform extensive Monte Carlo(MC)numerical simulations to verify the accuracy of our theoretical *** findings indicate that the activity levels of individuals in the disease transmission layer have a more significant influence on disease transmission compared with the individual activity levels in the information diffusion ***,reducing the damping factor can delay disease outbreaks and suppress disease transmission,while improving individual quarantine measures can contribute positively to disease *** study provides valuable insights into policymakers for developing outbreak prevention and control strategies.

关键词： information diffusion disease transmission asymmetric activity levels quarantine strength

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Price Masking Strategy of Cross-Border E-Commerce Platform Financing

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Journal of Systems science & Complexity 2024年第2期37卷 668-691页

作者： LI Jianbin HANG Zhouxin CHEN Zhiyuan XIAO Shan School of management Huazhong University of Science and TechnologyWuhan 430074China School of Economics and management Wuhan UniversityWuhan 430072China

E-commerce platform financing is a new service pattern of supply chain ***,this pattern may bring some new issues when considering the problem of cash flow shortage and financing difficulties of small and medium-sized *** enterprises use this service,they worry about the leakage of preferential wholesale price when applying the full loan amount and providing the true transaction *** on the model consisting of a supplier,a retailer and a cross-border e-commerce platform,the authors design a price masking strategy to prevent the retailer’s preferential wholesale price information from *** authors analyze the profit of the retailer and the platform before and after adopting the price masking *** authors find that the price masking strategy always benefits the ***,the optimal profit of the retailer and the platform are both affected by the loan interest ***,there exists a range of loan interest rates that can benefit both the retailer and the platform if the price masking strategy is *** research emphasizes that platform can expand the total business volume by allowing retailers to use price masking *** other words,there will be more and more retailers attracted by the strategy,which benefits the long-term growth of cross-border e-commerce platform financing.

关键词： Cross-border e-commerce e-commerce platform financing price masking supply chain finance

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health benefits from the rapid reduction in ambient exposure to air pollutants after China's clean air actions:progress in efficacy and geographic equality

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National science Review 2024年第2期11卷 103-113页

作者： Tao Xue Ruohan Wang Meng Wang Yanying Wang Dan Tong Xia Meng Conghong Huang Siqi Ai Fangzhou Li Jingyuan Cao Mingkun Tong Xueqiu Ni Hengyi Liu Jianyu Deng Hong Lu Wei Wan Jicheng Gong Shiqiu Zhang Tong Zhu Institute of Reproductive and Child health National Health Commission Key Laboratory of Reproductive Health/Department of Epidemiology and Biostatistics Ministry of Education Key Laboratory of Epidemiology of Major Diseases(PKU) School of Public Health Peking University Health Science Centre State Environmental Protection Key Laboratory of Atmospheric Exposure and Health Risk Management and Center for Environment and Health Peking University Advanced Institute of Information Technology Peking University Department of Epidemiology and Environmental health School of Public Health and Health ProfessionsUniversity at Buffalo State Key Joint Laboratory of Environment Simulation and Pollution Control College of Environmental Sciences and EngineeringPeking University Department of Earth System science Tsinghua University School of Public health Key Laboratory of Public Health Safety of the Ministry of Education and Key Laboratory of Health Technology Assessment of the Ministry of HealthFudan University College of Land management Nanjing Agricultural University National&Local Joint Engineering Research Center for Rural Land Resources Use and Consolidation Clean Air Asia

Clean air actions （CAAs） in China have been linked to considerable benefits in public ***,whether the beneficial effects of CAAs are equally distributed geographically is *** high-resolution maps of the distributions of major air pollutants (fine particulate matter[PM2.5]and ozone[O3]) and population,we aimed to track spatiotemporal changes in health impacts from,and geographic inequality embedded in,the reduced exposures to PM2.5and O3from 2013 to *** used a method established by the Global Burden of Diseases *** analyzing the changes in loss of life expectancy（LLE） attributable to PM2.5and O3,we calculated the gain of life expectancy （GLE） to quantify the health benefits of the air-quality ***,we assessed the geographic inequality embedded in the GLE using the Gini index （GI）.Based on risk assessments of PM2.5and O3,during the first stage of CAAs（2013 to 2017）,the mean GLE was 1.87 *** of the sum of the GLE was disproportionally distributed in about one quarter of the population exposed （GI 0.44）.During the second stage of CAAs（2017 to 2020）,the mean GLE increased to 3.94 months and geographic inequality decreased （GI 0.18）.According to our assessments,CAAs were enhanced,from the first to second stages,in terms of not only preventing premature mortality but also ameliorating health *** enhancements were related to increased sensitivity to the health effects of air pollution and synergic control of PM2.5and *** findings will contribute to optimizing future CAAs.

关键词： clean air action public health inequality fine particulate matter ozone

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Considering individual game behavior and time delay in the multi-channel rumor propagation model

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Communications in Theoretical Physics 2024年第7期76卷 11-31页

作者： Yafang Dong Liang'an Huo Xiaoxiao Xie Ming Li Business School University of Shanghai for Science and Technology School of Intelligent Emergency management University of Shanghai for Science and Technology

The rapid development of the Internet has accelerated the spread of rumors, posing challenges to social cohesion and stability. To address this, a multi-channel rumor propagation model incorporating individual game behavior and time delay is proposed. It depicts individuals strategically choosing propagation channels in the rumor spread process, capturing real-world intricacies more faithfully. Specifically, the model allowing spreaders to choose between text and video information base channels. Strategy adoption hinges on benefits versus costs, with payoffs dictating strategy and the propagation process determining an individual's state. By theoretical analysis of the model, the propagation threshold and equilibrium points are obtained. Then the stability of the model is further demonstrated based on Routh–Hurwitz judgment and Descartes' Rule of Signs. Numerical simulations are conducted to verify the correctness of the theoretical results and the sensitivity of the model to key parameters. The outcomes reveal that increasing the propagation cost of spreaders can significantly curb the spread of rumors. In contrast to the classical ISR model, rumors spread faster and more widely in the improved multi-channel rumor propagation model in this paper, which is a feature more aligned with real-world ***, the validity and predictive ability of the model are verified by using real rumor propagation data sets, indicating that the improved multi-channel rumor propagation model has good practical application and predictive value.

关键词： game behavior multi-channel rumor propagation time delay

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Models to Simulate Effective Coverage of Fire Station Based on Real-Time Travel Times

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Computer Modeling in Engineering & sciences 2024年第4期139卷 483-513页

作者： Sicheng Zhu Dingli Liu Weijun Liu Ying Li Tian Zhou Department of Engineering management Changsha University of Science and TechnologyChangsha410114China

In recent years,frequent fire disasters have led to enormous damage in *** firefighting rescues can minimize the losses caused by *** the rescue processes,the travel time of fire trucks can be severely affected by traffic conditions,changing the effective coverage of fire ***,it is still challenging to determine the effective coverage of fire stations considering dynamic traffic *** paper addresses this issue by combining the traveling time calculationmodelwith the effective coverage *** addition,it proposes a new index of total effective coverage area(TECA)based on the time-weighted average of the effective coverage area(ECA)to evaluate the urban fire *** also selects China as the case study to validate the feasibility of the models,a fire station(FS-JX)in ***-JX station and its surrounding 9,117 fire risk points are selected as the fire service supply and demand points,respectively.A total of 196 simulation scenarios throughout a consecutiveweek are ***,1,933,815 sets of valid sample data are *** results showed that the TECA of FS-JX is 3.27 km^(2),which is far below the standard requirement of 7.00 km^(2) due to the traffic *** visualization results showed that three rivers around FS-JX interrupt the continuity of its effective *** proposed method can provide data support to optimize the locations of fire stations by accurately and dynamically determining the effective coverage of fire stations.

关键词： Fire services fire station effective coverage real-time traffic simulation

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Studying the co-evolution of information diffusion,vaccination behavior and disease transmission in multilayer networks with local and global effects

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Chinese Physics B 2024年第3期33卷 677-689页

作者：霍良安武兵杰 Business School University of Shanghai for Science and TechnologyShanghai 200093China School of Intelligent Emergency management University of Shanghai for Science and TechnologyShanghai 200093China

Today,with the rapid development of the internet,a large amount of information often accompanies the rapid transmission of disease outbreaks,and increasing numbers of scholars are studying the relationship between information and the disease transmission process using complex *** fact,the disease transmission process is very *** this information,there will often be individual behavioral measures and other factors to *** of the previous research has aimed to establish a two-layer network model to consider the impact of information on the transmission process of disease,rarely divided into information and behavior,*** carry out a more in-depth analysis of the disease transmission process and the intrinsic influencing mechanism,this paper divides information and behavior into two layers and proposes the establishment of a complex network to study the dynamic co-evolution of information diffusion,vaccination behavior,and disease *** is achieved by considering four influential relationships between adjacent layers in multilayer *** the information layer,the diffusion process of negative information is described,and the feedback effects of local and global vaccination are *** the behavioral layer,an individual's vaccination behavior is described,and the probability of an individual receiving a vaccination is influenced by two factors:the influence of negative information,and the influence of local and global disease *** the disease layer,individual susceptibility is considered to be influenced by vaccination *** state transition equations are derived using the micro Markov chain approach(MMCA),and disease prevalence thresholds are *** is demonstrated through simulation experiments that the negative information diffusion is less influenced by local vaccination behavior,and is mainly influenced by global vaccination behavior;vaccination behavior is mainly influenced by local d

关键词： information diffusion vaccination behavior disease transmission multilayer networks local and global effect

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