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Interaction between the left ventricular ejection fraction and left ventricular strain and its relationship with coronary stenosis

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World Journal of Clinical Cases 2023年第10期11卷 2246-2253页

作者： Hai-Yan Gui Shu-Wen Liu Dong-Fang Zhu mri room Harbin No.4 HospitalHarbin 150026Heilongjiang ProvinceChina Department of Cardiology Harbin No.4 HospitalHarbin 150026Heilongjiang ProvinceChina

BACKGROUND Coronary artery stenosis(CAS)is the most common type of heart disease and the leading cause of death in both men and women *** occurs when the arteries that supply blood to the heart muscle harden and become narrower due to plaque buildup-cholesterol and other material-on their inner *** a result,the heart muscle cannot receive the blood or oxygen it *** heart attacks happen when a blood clot suddenly cuts off the hearts'blood supply,causing permanent heart *** To analyze the relationship between the left ventricular ejection fraction(LVEF),left ventricular strain(LVS),and coronary *** A total of 190 participants were enrolled in this *** control group comprised 93 healthy individuals,and observation group comprised 97 patients with coronary heart disease who were hospitalized between July 2020 and September *** lesions were assessed using the Gensini score,and the LVEF and LVS were measured using magnetic resonance imaging(mri).The interaction between the LVEF and LVS was examined using a linear regression *** relationship between LVEF and coronary stenosis was examined using Spearman’s *** The LVEF of the observation group was lower than that of the control *** left ventricular end-systolic volume(LVESV)and left ventricular end-diastolic volume(LVEDV)of the observation group were significantly higher than those of the control group(P<0.05).The longitudinal and circumferential strains(LS,CS)of the observation group were significantly higher than those of the control group;however,the radial strain(RS)of the observation group was significantly lower than that of the control group(P<0.05).LVS,LS,and CS were significantly negatively correlated with the LVEF,and RS was positively correlated with the *** were significant differences in the LVEF,LVESV,and LVEDV of patients with different Gensini scores;the LVEF significantly decreased and the LVESV and LVEDV increased w

关键词： Magnetic resonance imaging Left ventricular ejection fraction Left ventricular strain Coronary stenosis Left ventricular end-diastolic volume Left ventricular end-systolic volume

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Abnormal activation of the occipital lobes during emotion picture processing in major depressive disorder patients

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Neural Regeneration Research 2013年第18期8卷 1693-1701页

作者： Jianying Li Cheng Xu Xiaohua Cao Qiang Gao Yan Wang Yanfang Wang Juyi Peng Kerang Zhang Department of Mental Health First Hospital of Shanxi Medical University mri room Shanxi Provincial People's Hospital

A large number of studies have demonstrated that depression patients have cognitive dysfunction. With recently developed brain functional imaging, studies have focused on changes in brain function to investigate cognitive changes. However, there is still controversy regarding abnormalities in brain functions or correlation between cognitive impairment and brain function changes. Thus, it is important to design an emotion-related task for research into brain function changes. We selected positive, neutral, and negative pictures from the International Affective Picture System. Patients with major depressive disorder were asked to judge emotion pictures. In addition, functional mri was performed to synchronously record behavior data and imaging data. Results showed that the total correct rate for recognizing pictures was lower in patients compared with normal controls. Moreover, the consistency for recognizing pictures for depressed patients was worse than normal controls, and they frequently recognized positive pictures as negative pictures. The consistency for recognizing pictures was negatively correlated with the Hamilton Depression Rating Scale. Functional mri suggested that the activation of some areas in the frontal lobe, temporal lobe, parietal lobe, limbic lobe, and cerebellum was enhanced, but that the activation of some areas in the frontal lobe, parietal lobe and occipital lobe was weakened while the patients were watching positive and neutral pictures compared with normal controls. The activation of some areas in the frontal lobe temporal lobe, parietal lobe, and limbic lobe was enhanced, but the activation of some areas in the occipital lobe were weakened while the patients were watching the negative pictures compared with normal controls. These findings indicate that patients with major depressive disorder have negative cognitive disorder and extensive brain dysfunction. Thus, reduced activation of the occipital lobe may be an initiating factor for cogni

关键词： neural regeneration neuroimaging major depressive disorder, cognitive function functional mri occipitallobe emotion grants-supported paper neuro^-:EJeneration

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Compensatory recombination phenomena of neurological functions in central dysphagia patients

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Neural Regeneration Research 2015年第3期10卷 490-497页

作者： Xiao-dong Yuan Li-fu Zhou Shu-juan Wang Yan-sheng Zhao Xiao-jie Wang Li-li Zhang Shou-hong Wang Ya-jie Zhang Li Chen Department of Neurology Affiliated Kailuan General Hospital of Hebei United University Department of mri room Affiliated Kailuan General Hospital of Hebei United University

We speculate that cortical reactions evoked by swallowing activity may be abnormal in patients with central infarction with dysphagia. The present study aimed to detect functional imaging features of cerebral cortex in central dysphagia patients by using blood oxygen level-depen- dent functional magnetic resonance imaging techniques. The results showed that when normal controls swallowed, primary motor cortex （BA4）, insula （BA13）, premotor cortex （BA6/8）, supramarginal gyrus （BA40）, and anterior cingulate cortex （BA24/32） were activated, and that the size of the activated areas were larger in the left hemisphere compared with the right. In re- current cerebral infarction patients with central dysphagia, BA4, BA13, BA40 aild BA6/8 areas were activated, while the degree of activation in BA24/32 was decreased. Additionally, more areas were activated, including posterior cingulate cortex （BA23/31）, visual association cortex （BA18/19）, primary auditory cortex （BA41） and parahippocampal cortex （BA36）. Somatosen- sory association cortex （BA7） and left cerebellum in patients with recurrent cerebral infarction with central dysphagia were also activated. Experimental findings suggest that the cerebral cortex has obvious hemisphere lateralization in response to swallowing, and patients with recurrent cerebral infarction with central dysphagia show compensatory recombination phenomena of neurological functions. In rehabilitative treatment, using the favorite food of patients can stimu- late swallowing through visual, auditory, and other nerve conduction pathways, thus promoting compensatory recombination of the central cortex functions.

关键词： nerve regeneration blood oxygen level-dependent functional magnetic resonance imag-ing cerebral ischemia dysphagia function restructuring cerebral cortex neural regeneration

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Proton magnetic resonance spectroscopy in the evaluation of infiltration zone of cerebral alveolar echinococcosis

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Chinese Medical Journal 2012年第13期125卷 2260-2264页

作者： WANG Jian YAO Wei-hong YI Ba-nu LIU Shen ZHANG De-qing JIANG Chun-hui ZHANG Li-min NIU Jun-qiao JIA Wen-xiao WEN Hao Imaging Center/mri room Department ofNeurosurgeryFirst Affiiiated Hospital Xinjiang MedicalUniversity Urmqi Xinjiang 830011 China Xinjiang Clinical Research Institute of Echinococcosis Urumqi Xinjiang 830011 China

Background Cerebral alveolar echinococcosis （CAE） grows infiltratively like a malignant tumor, causing great harm to the human body. It is possible to display mass lesions of CAE using various imaging systems, but regarding the infiltrating proliferation active regions, it is difficult to evaluate its actual range using conventional magnetic resonance imaging （cmri）. This research focused on proton magnetic resonance spectroscopy （1HMRS） techniques to find the mass and infiltration zone of CAE. We explored the marginal zone （MZ） of CAE nearly close to the actual infiltrating scope, to provide reliable images for clinical purposes, to overcome shortcomings of cmri, to formulate beneficial clinical surgical plans and assess prognosis. Methods Between September 2005 and May 2011, 15 patients who were suffering from CAE （36 effective lesions altogether） were examined by 1HMRS at the first affiliated hospital of Xinjiang Medical University. Multi-voxel 1HMRS was acquired with a 1.5T mri scanner. Concentrations and the ratios of the metabolites of CAE were calculated. Furthermore, changes in the concentrations of the metabolites containing N-acetyl-aspartic-acid （NAA）, choline （Cho）, creatine （Cr）, lipids and lactate （Lip＋Lac） and the ratios of Cho/Cr, NAA/Cr, （Lip＋Lac）/Cr were compared in the substantial region, 0-10 rnm MZ, and 11-20 mm MZ of the infiltration zone, as well as the corresponding contralateral part of the normal brain parenchyma area （control group）. Results In this study, the ratios of Cho/Cr in the substantial region, 0-10 mm MZ of infiltration zone and the control group were 1.78＋0.70, 1.90＋_0.54, and 0.78＋_0.15, respectively; the ratios of NAA/Cr were 1.60＋0.20, 1.80＋0.42, 2.24＋_0.86, respectively; the ratios of （Lip＋Lac）/Cr were 25.69＋_13.84, 25.18＋16.03, and 0.61 ＋0.15, respectively. From the control group, 11-20 mm MZ to 0-10 mm MZ and the substantial region of CAE, the concentrations of the metabolites showed that NAA and Cho decreased gradually an

关键词： cerebral alveolar echinococcosis marginal zone magnetic resonance spectroscopy evaluation

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1H magnetic resonance spectroscopy and diffusion weighted imaging findings of medulloblastoma in 3.0T mri A retrospective analysis of 17 cases

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Neural Regeneration Research 2012年第32期7卷 2554-2559页

作者： Prasanna Ghimire MR room Zhongnan Hospital of Wuhan University

1H magnetic resonance spectroscopy and diffusion weighted imaging features of the cerebellar vermis in 17 medulloblastoma patients were retrospectively analyzed, and 17 healthy volunteers were selected as controls. 1H magnetic resonance spectroscopy showed that in all 17 medulloblastoma patients, N-acetyl aspartate and creatine peaks were significantly decreased, the choline peak was significantly increased, and there was evidence of a myo-inositol peak. Further, 11 patients showed a low taurine peak at 3.4 ppm, five patients showed a lipid peak at 0.9-1.3 ppm, and three patients showed a negative lactic acid peak at 1.33 ppm. Compared with the control group, the ratios of N-acetyl aspartate/choline and N-acetyl aspartate/creatine were significantly decreased, and the ratio of choline/creatine was increased, in medulloblastoma patients. Diffusion weighted imaging displayed hyperintensity and decreased apparent diffusion coefficient in medulloblastoma patients. These findings indicate that 1H magnetic resonance spectroscopy and diffusion weighted imaging are useful for qualitative diagnosis of medulloblastoma.

关键词： medulloblastoma proton magnetic resonance spectroscopy diffusion weighted imaging apparent diffusion coefficient N-acetyl aspartate choline creatine taurine lactic acid myo-inositol

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Magnetic resonance imaging combined with serum endolipin and galactagoglobin-3 to diagnose cerebral infarction in the elderly with diabetes mellitus

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World Journal of Diabetes 2024年第7期15卷 1509-1517页

作者： Yan-Hui Zhang Dong Liang Magnetic Resonance Imaging room Tianjin Huanhu HospitalTianjin 300350China Department of Endocrinology Tianjin First Central HospitalTianjin 300190China

BACKGROUND Magnetic resonance imaging(mri)combined with serum endothelin and galactagoglobin-3(Gal-3)can improve the clinical diagnosis of diabetes mellitus complicated with cerebral *** To analyze the clinical value of mri combined with serum endolipin and Gal-3 for the diagnosis of cerebral infarction in the elderly with diabetes *** One hundred and fifty patients with acute cerebral infarction hospitalized between January 2021 and December 2023 were divided into two groups according to comorbid diabetes mellitus,including 62 and 88 cases in the diabetic and nondiabetic cerebral infarction *** samples were collected to detect the expression of serum endolipoxins,and Gal-3,and cranial mri was performed at *** between the two groups were compared to analyze the diagnostic value of these *** Serum endolipin and Gal-3 expression were higher in the diabetic cerebral infarction group(P<0.05).The arterial wall area,vessel area,normalized wall index,and lumen stenosis rate were higher in the diabetic cerebral infarction group,while the rate of arterial lumen moderate and severe stenosis was 48.39% higher(36.36%,P<0.05).The percentage of large(29.03%)and multiple infarcts(33.87%)in the diabetic cerebral infarction group was higher(13.64% and 20.45%),and the incidence rate of lacunar infarcts was lower(37.10%vs 65.91%)(P<0.05).The total incidence of arterial plaque in patients in the diabetic cerebral infarction group was 96.77% higher(69.32%),while the incidence of necrotic lipid core plaque was 58.06%higher(26.14%)(P<0.05).Receiver operating characteristic curve analysis was performed to assess the diagnosis utility of these *** in combination with serum endoglin and Gal-3 had the highest area under the curve,the Yoden index,sensitivity and specificity(P<0.05).CONCLUSION The expression of serum endolipin and Gal-3 in elderly patients with diabetes mellitus with cerebral infarction showed an eleva

关键词： Endolipin Galectin-3 Magnetic resonance imaging Elderly Diabetes mellitus Cerebral infarction

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MR三维SPACE序列评估正常膝后外侧角韧带结构的价值

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临床放射学杂志 2018年第3期37卷 476-480页

作者：赵晓梅黄耀渠伍琼慧樊长姝广东省佛山市中医院mri室

目的探讨三维质子密度不同翻转角步进最佳对比应用完善取样（3D PD-SPACE）序列评估正常膝后外侧角（PLC）韧带结构的价值,提高对相应结构的认识。方法 35名无症状志愿者行常规3个平面二维质子密度加权（2D PDWI）序列及3D PD-SPACE序... 详细信息

目的探讨三维质子密度不同翻转角步进最佳对比应用完善取样（3D PD-SPACE）序列评估正常膝后外侧角（PLC）韧带结构的价值,提高对相应结构的认识。方法 35名无症状志愿者行常规3个平面二维质子密度加权（2D PDWI）序列及3D PD-SPACE序列检查,采用4分法评价2个序列显示正常PLC的外侧副韧带、腘腓韧带、弓状韧带和小豆腓骨韧带的价值。结合薄层原始图像和多向调整多平面重组（MPR）分析各韧带的mri表现和解剖学参数。结果 3D PD-SPACE序列显示外侧副韧带、腘腓韧带、弓状韧带和小豆腓骨韧带的评分均优于2D PDWI序列（P均〈0.05）。3D PD-SPACE序列多向调整MPR对外副韧带、腘腓韧带、弓状韧带、小豆腓骨韧带的显示率分别为100%（35/35）、100%（35/35）、74.3%（26/35）和51.4%（18/35）。正常外侧副韧带的长度、宽度和厚度分别为（51.6±7.5）mm、（4.0±1.0）mm及（4.9±1.2）mm,腘腓韧带为（13.8±2.6）mm、（8.5±3.7）mm及（2.6±0.49）mm,弓状韧带中部分别为（20.9±5.8）mm、（12.2±2.8）mm及（2.0±0.72）mm,小豆腓骨韧带则为（32.3±5.6）mm、（2.4±0.58）mm及（1.4±0.26）mm;各韧带不同性别间和左右间差异无统计学意义（P均〉0.05）。结论3D PD-SPACE序列结合多向调整MPR能准确显示PLC小韧带的解剖形态,是评估该类结构的有效手段。

关键词：膝关节韧带解剖学磁共振成像

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Magnetic Resonance Imaging Findings of Olfactory Bulb in Anosmic Patients with COVID-19: A Systematic Review

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Chinese Medical Sciences Journal 2022年第1期37卷 23-30页

作者： Atefeh Beigi-khoozani Amirmohammad Merajikhah Mahdieh Soleimani Department of Operating room Iran University of Medical SciencesTehranIran Department of Operating room Sabzevar University of Medical SciencesRazavi KhorasanIran Department of Operating room Maragheh University of Medical SciencesEast AzerbaijanIran

Background Anosmia is one of the symptoms in individuals with SARS-CoV-2 *** anosmic patients,SARS-CoV-2 temporarily alters the signaling process in olfactory nerve cells and olfactory bulb(OB),which eventually damages the structure of the olfactory epithelium,leading to a permanent disorder in the olfactory pathway that this damaged structure is showed in mri imaging Method Two investigators independently searched four databases consisting of PubMed,ProQuest,Scopus,and Web of Science for relevant records as of November 11,2020 with no time,space,and language *** Scholar was also searched for the related resources within the time limit of *** the found articles were reviewed based on the PRISMA flow *** studies,case reports,editorials,letters,and other non-original studies were excluded from this systematic *** Initial search yielded 434 *** reviewing the titles and abstracts,we selected 74 articles;finally,8 articles were depicted to be investigated and read in full *** obtained results showed an increase in the width and volume of the olfactory cleft(OC),complete or partial destruction of OC,and complete occlusion of OC in COVID-19 *** and degeneration as well as a subtle asymmetry were evident in the *** tomography(CT),meganetic resonance imaging(mri),and positron emission tomography(PET)were used to detect the outcomes of anosmia in these *** The changes in OC are greater than those in OB in patients with COVID-19,mainly due to the inflammatory and immune responses in ***,fewer changes in OB are due to neurological or vascular *** steroid therapy and topical saline can be helpful.

关键词： magnetic resonance imaging olfactory bulb COVID-19 anosmia

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Aptamer-functionalized nanoplatforms overcoming temozolomide resistance in synergistic chemo/photothermal therapy through alleviating tumor hypoxia

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Nano Research 2023年第7期16卷 9859-9872页

作者： Yun Zeng Linfei Zhao Ke Li Jingwen Ma Dan Chen Changhu Liu Wenhua Zhan Yonghua Zhan School of Life Science and Technology Xidian University and Engineering Research Center of Molecular and Neuro ImagingMinistry of EducationXi’an 710126China Department of Radiation Oncology General Hospital of Ningxia Medical UniversityYinchuan 750004China International Joint Research Center for Advanced Medical Imaging and Intelligent Diagnosis and Treatment and Xi’an Key Laboratory of Intelligent Sensing and Regulation of trans-Scale Life Information School of Life Science and TechnologyXidian UniversityXi’an 710126China Xi’an Key Laboratory for Prevention and Treatment of Common Aging Diseases Translational and Research Centre for Prevention and Therapy of Chronic DiseaseInstitute of Basic and Translational MedicineXi’an Medical UniversityXi’an 710021China Radiology Department CT and MRI RoomNinth Hospital of Xi’anXi’an 710054China

Tumor hypoxia is intimately associated with gliomas,which represents a significant threat to human health and are resistant to the first-line chemotherapeutic drug temozolomide(TMZ)due to *** this work,to overcome TMZ resistance in orthotopic gliomas,aptamer-functionalized liposomes are manufactured to encapsulate TMZ and photothermal agent IR780,and can cross the blood-brain barrier and actively target *** is possible to employ liposomes for both fluorescence and photoacoustic imaging simultaneously due to their stability and excellent photothermal conversion *** chemo/photothermal synergistic therapeutic effect of liposomes on gliomas is demonstrated by their abilities to target orthotopic gliomas,alleviate tumor hypoxia and consequently reverse resistance of glioma cells to TMZ,thereby extending the survival time of tumor-bearing mice,making the nanoplatforms and their synergistic chemo/photothermal therapy as a potential clinical treatment for gliomas.

关键词： aptamers blood-brain barrier gliomas liposomes photothermal therapy

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高分辨磁共振成像对颈动脉粥样硬化斑块表面钙化与斑块稳定性关系研究

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临床荟萃 2012年第6期27卷 495-496,499页

作者：彭少华王成伟尹喜 PENG Shaohua WANG Chengwei YIN Xi 新疆石河子大学第一附属医院mri室新疆石河子832002 Department of mri room the First Affiliated Hospital of Shihezi University Shihezi 832002 China

目的通过高分辨磁共振成像(mri)多序列扫描,分析颈动脉粥样硬化斑块的表面钙化的形状、位置与斑块稳定性的关系。方法运用高分辨mri多序列(3D-TOF、DIR T1WI、FSE T2WI、PDWI)对34例颈动脉斑块患者进行扫描,分析钙化类型和位置与斑块表... 详细信息

目的通过高分辨磁共振成像(mri)多序列扫描,分析颈动脉粥样硬化斑块的表面钙化的形状、位置与斑块稳定性的关系。方法运用高分辨mri多序列(3D-TOF、DIR T1WI、FSE T2WI、PDWI)对34例颈动脉斑块患者进行扫描,分析钙化类型和位置与斑块表面溃疡的关系。结果 87层表面钙化斑块,59层(67.8%)见斑块表面溃疡。按钙化类型和部位划分,64层为点状、弧形的不规则钙化,23层为大片状钙化;58层为边缘钙化,29层为中央钙化。不规则钙化组伴斑块表面溃疡的概率显著高于大片状钙化组;边缘钙化组较中央钙化组更易伴斑块表面溃疡。结论表面钙化是斑块不稳定的重要因素之一,容易导致斑块表面溃疡形成;表面钙化的类型、部位对斑块的稳定性有重要影响。

关键词：动脉硬化磁共振成像诊断,计算机辅助

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