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柔性界面分子智能感知

Science Bulletin 2024年第5期69卷 578-582页

作者：吴双双刘松瑞李婷李金星汪联辉王婷 State Key Laboratory of Organic Electronics and Information Displays&Jiangsu Key Laboratory for Biosensors Institute of Advanced Materials(IAM)Jiangsu National Synergetic Innovation Center for Advanced Materials(SICAM)Nanjing University of Posts and TelecommunicationsNanjing 210023China Department of Biomedical Engineering and Institute for Quantitative Health Science and Engineering(IQ) Michigan State UniversityEast Lansing MI 48823USA

A series of captivating and intricate information exchanges occur on soft interfaces(such as cells interface,tissue surface or soft epidermis),whether among simple microorganisms like bacteria or in the most complex organisms like humans,such as ion diffusion across capillary membranes,neurotransmitter exchanges among synapses,and sweat secretion through sweat *** these signals and emulating these interactions on biological interfaces will contribute to a better understanding of physiological processes and diseases,as well as the study of the humanmachine *** example is continuous real-time monitoring of physiological cues,like glucose levels in sweat,allowing for effective diabetes assessment and timely insulin therapy[1].

关键词：智能感知 diseases capillary

Flexible, diamond-based microelectrodes fabricated using the diamond growth side for neural sensing

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microsystems & Nanoengineering 2020年第1期6卷 742-753页

作者： Bin Fan Cory A.Rusinek Cort H.Thompson Monica Setien Yue Guo Robert Rechenberg Yan Gong Arthur J.Weber michael F.Becker Erin Purcell Wen Li Department of Electrical and Computer Engineering Michigan State UniversityEast LansingMIUSA Fraunhofer USA Center for Coatings and Diamond Technologies East LansingMIUSA Department of Biomedical Engineering Michigan State UniversityEast LansingMIUSA Department of Physiology Michigan State UniversityEast LansingMIUSA

Diamond possesses many favorable properties for biochemical sensors,including biocompatibility,chemical inertness,resistance to biofouling,an extremely wide potential window,and low double-layer *** hardness of diamond,however,has hindered its applications in neural implants due to the mechanical property mismatch between diamond and soft nervous ***,we present a flexible,diamond-based microelectrode probe consisting of multichannel boron-doped polycrystalline diamond(BDD)microelectrodes on a soft Parylene C *** developed and optimized a wafer-scale fabrication approach that allows the use of the growth side of the BDD thin film as the sensing *** to the nucleation surface,the BDD growth side exhibited a rougher morphology,a higher sp^(3) content,a wider water potential window,and a lower background *** dopamine(DA)sensing capability of the BDD growth surface electrodes was validated in a 1.0 mM DA solution,which shows better sensitivity and stability than the BDD nucleation surface *** results of these comparative studies suggest that using the BDD growth surface for making implantable microelectrodes has significant advantages in terms of the sensitivity,selectivity,and stability of a neural ***,we validated the functionality of the BDD growth side electrodes for neural recordings both in vitro and in *** biocompatibility of the microcrystalline diamond film was also assessed in vitro using rat cortical neuron cultures.

关键词： neural film diamond

Compact prototype microfabricated gas chromatographic analyzer for autonomous determinations of VOC mixtures at typical workplace concentrations

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microsystems & Nanoengineering 2018年第1期4卷 390-399页

作者： Junqi Wang Jonathan Bryant-Genevier Nicolas Nuñovero Chengyi Zhang Bruce Kraay Changhua Zhan Kee Scholten Robert Nidetz Sanketh Buggaveeti Edward T.Zellers Department of Chemistry University of MichiganAnn ArborMI 48109USA Department of Environmental Health Sciences University of MichiganAnn ArborMI 48109USA Applied Physics Program University of MichiganAnn ArborMI 48109USA Department of Mechanical Engineering University of MichiganAnn ArborMI 48109USA Center for Wireless Integrated microSensing and Systems University of MichiganAnn ArborMI 48109USA

This report concerns a benchtop prototype instrument containing a gas chromatographic microanalytical system(μGC)designed for the selective determination of multiple airborne volatile organic compounds(VOCs)at concentrations in the vicinity of recommended occupational exposure *** core microsystem consists of a set of discrete Si-microfabricated devices:a dualcavity,adsorbent-packed micro-preconcentrator-focuser(μPCF)chip that quantitatively captures and thermally desorbs/injects VOCs with vapor pressures between~0.03 and 13 kPa;tandem micro-column(μcolumn)chips with cross-linked PDMS wall-coated stationary phases capable of temperature-programmed separations;and an integrated array of fiveμchemiresistors(μCR)coated with different thiolate-monolayer protected gold nanoparticle(MPN)interface films that quantifies and further differentiates among the analytes by virtue of the response patterns *** key components include a pre-trap for low-volatility interferences,a split-flow injection valve,and an onboard He carrier–gas *** assembled unit measures 19×30×14 cm,weighs~3.5 kg,operates on AC power,and is laptop/LabVIEW ***-and system-level tests of performance demonstrated injection bandwidths o1 s,aμcolumn capacity of≥8μg injected mass,linear calibration curves,no humidity effects,excellent medium-term(that is,1 week)reproducibility,autonomous operation for 8 h,detection limits below Threshold Limit Values(TLV)for 10 mL air samples collected in 1 min,and response patterns that enhanced vapor *** determination of a 17-VOC mixture in the presence of seven interferences was performed in 4 *** augur well for adapting the microsystem to an all-MEMS wearableμGC currently under parallel development.

关键词： gas chromatography micro-GC microsystem mixtures sensor array VOCs

压铸过程中铸件-铸型界面换热系数与铸件凝固速率的关系

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金属学报 2009年第1期45卷 102-106页

作者：郭志鹏熊守美 Mei Li John Allison 清华大学机械工程系先进成形制造教育部重点实验室北京100084 Research ＆ Advanced Engineering Department Scientific Research Laboratory Ford Motor Company Dearborn MI 48121 USA

在实际压铸实验的基础上,求解了铸件-铸型界面换热系数h与铸件凝固速率v的关系.结果表明,二者呈线性变化关系:h=k_(h-v)·v+ω(其中,斜率k_(h-v)为铸型初始表面温度及铸件厚度的函数,ω为常数);通过线性拟合确定k_(h-v)和ω值,从而确立... 详细信息

在实际压铸实验的基础上,求解了铸件-铸型界面换热系数h与铸件凝固速率v的关系.结果表明,二者呈线性变化关系:h=k_(h-v)·v+ω(其中,斜率k_(h-v)为铸型初始表面温度及铸件厚度的函数,ω为常数);通过线性拟合确定k_(h-v)和ω值,从而确立换热系数与铸件凝固速率的关系.这种关系同时适用于镁合金AM50和铝合金ADC12.

关键词：压铸界面换热系数凝固速率镁合金AM50 铝合金ADC12

Tunable photonic crystals based on ferroelectric and ferromagnetic materials by focused ion beam

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Chinese Optics Letters 2007年第12期5卷 693-695页

作者： Ziyou Zhou Xiaoyue Huang Raghav Vanga Rong Li Physics Department Michigan Technological University Houghton MI 49931 USA Material Science and Engineering Department Michigan Technological University Houghton MI 49931 USA

By making photonic crystals in ferroelectric and ferromagnetic materials, field-provoked tunability of photonic crystals is broadening the interest in new applications of on-chip photonic devices. We report a nano-precise fabrication of various designs of photonic crystals in these non-conventional materials using the focused ion beam milling technique. Standard methods are developed and parameters for different materials are calibrated. Optical responses such as bandgaps and polarization status changing from planar film waveguide svstem with these patterns have been examined on ferromagnetic materials.

关键词： Computer aided design Electron beam lithography Ion beams Photonic crystals Photonic devices Thin films

Potential Analysis on Carnot Groups,Part Ⅱ:Relationship between Hausdorff Measures and Capacities

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Acta Mathematica Sinica,English Series 2004年第1期20卷 25-46页

作者： CuoZhenLU DepartmentofMathematics WayneStateUniversityDetroitMI48202USA

In this paper,we establish the relationship between Hausdorff measures and Bessel capac- ities on any nilpotent stratified Lie group G (i.e.,Carnot group).In particular,as a special corollary of our much more general results,we have the following theorem (see Theorems A and E in Section 1): Let Q be the homogeneous dimension of *** any set E(?)G,B_(α,p)(E)=0 implies (?)^(Q-αp+(?))(E)=0 for all (?)>*** the other hand,(?)^(Q-αp)(E)<∞ implies B_(α,p)(E)=***- quently,given any set E(?)G of Hausdorff dimension Q-d,where 0

关键词： Sobolev spaces Stratified groups Bessel capacities Hausdorff measures Radon measures

Magnetohydrodynamic behaviors in a resistance spot weld nugget under different welding currents

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Science China(Technological Sciences) 2008年第9期51卷 1507-1515页

作者： S. Jack HU The University of michigan Ann Arbor MI 48109 USA

Magnetohydrodynamic behaviors in a resistance spot weld nugget under different welding currents are investigated based on a multiphysics coupled numerical model, which incorporates phase change and variable electrical contact resis-tances at faying surface and electrode-workpiece contact surface. The patterns of the flow field and thermal field at the end of the welding phase under different welding currents are obtained. The evolutions of fluid flow and heat transfer during the whole welding process are also revealed systematically. The analysis results are also compared with a traditional electrothermal coupled model to obtain the quantitative effects of the magnetohydrodynamic behaviors on the resistance spot weld nugget formation.

关键词： resistance spot welding magnetic force fluid flow heat transfer

Macro-architectured cellular materials： Properties, characteristic modes, and prediction methods

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Frontiers of Mechanical Engineering 2018年第3期13卷 442-459页

作者： Zheng-Dong MA The University of michigan Ann Arbor MI 48109 USA

Macro-architectured cellular （MAC） material is defined as a class of engineered materials having configurable cells of relatively large （i.e., visible） size that can be architecturally designed to achieve various desired material properties. Two types of novel MAC materials, negative Poisson＇s ratio material and biomimetic tendon reinforced material, were introduced in this study. To estimate the effective material properties for structural analyses and to optimally design such materials, a set of suitable homogenization methods was developed that provided an effective means for the multiscale modeling of MAC materials. First, a strain-based homogenization method was developed using an approach that separated the strain field into a homogenized strain field and a strain variation field in the local cellular domain superposed on the homogenized strain field. The principle of virtual displacements for the relationship between the strain variation field and the homogenized strain field was then used to condense the strain variation field onto the homogenized strain field. The new method was then extended to a stress-based homogenization process based on the principle of virtual forces and further applied to address the discrete systems represented by the beam or frame structures of the aforementioned MAC materials. The characteristic modes and the stress recovery process used to predict the stress distribution inside the cellular domain and thus determine the material strengths and failures at the local level are also discussed.

关键词： architectured material cellular materials multi-scale modeling homogenization method effective material properties computational method

Growth-Defense Tradeoffs in Plants： A Balancing Act to Optimize Fitness

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Molecular Plant 2014年第8期7卷 1267-1287页

作者： Bethany Huot Jian Yao Beronda L. Montgomery' Sheng Yang He Department of Energy Plant Research Laboratory Michigan State University MI 48824 USA Cell and Molecular Biology Program Michigan State University MI 48824 USA Department of Biochemistry and Molecular Biology Michigan State University MI 48824 USA Department of Plant Biology Michigan State University MI 48824 USA Howard Hughes Medical Institute-Gordon and Betty Moore Foundation Michigan State University MI 48933 USA

Growth-defense tradeoffs are thought to occur in plants due to resource restrictions, which demand prior- itization towards either growth or defense, depending on external and internal factors. These tradeoffs have profound implications in agriculture and natural ecosystems, as both processes are vital for plant survival, reproduction, and, ulti- mately, plant fitness. While many of the molecular mechanisms underlying growth and defense tradeoffs remain to be elucidated, hormone crosstalk has emerged as a major player in regulating tradeoffs needed to achieve a balance. In this review, we cover recent advances in understanding growth-defense tradeoffs in plants as well as what is known regard- ing the underlying molecular mechanisms. Specifically, we address evidence supporting the growth-defense tradeoff concept, as well as known interactions between defense signaling and growth signaling. Understanding the molecular basis of these tradeoffs in plants should provide a foundation for the development of breeding strategies that optimize the growth-defense balance to maximize crop yield to meet rising global food and biofuel demands.

关键词： plant immunity plant hormone salicylic acid jasmonate PAMP plant growth.