Compact prototype microfabricated gas chromatographic analyzer for autonomous determinations of VOC mixtures at typical workplace concentrations

作     者：Junqi Wang Jonathan Bryant-Genevier Nicolas Nuñovero Chengyi Zhang Bruce Kraay Changhua Zhan Kee Scholten Robert Nidetz Sanketh Buggaveeti Edward T.Zellers 

作者机构：Department of ChemistryUniversity of MichiganAnn ArborMI 48109USA Department of Environmental Health SciencesUniversity of MichiganAnn ArborMI 48109USA Applied Physics ProgramUniversity of MichiganAnn ArborMI 48109USA Department of Mechanical EngineeringUniversity of MichiganAnn ArborMI 48109USA Center for Wireless Integrated MicroSensing and SystemsUniversity of MichiganAnn ArborMI 48109USA 

出 版 物：《Microsystems & Nanoengineering》 (微系统与纳米工程（英文）)

年 卷 期：2018年第4卷第1期

页      面：390-399页

核心收录：

学科分类：08[工学] 0812[工学-计算机科学与技术（可授工学、理学学位）] 

基　　金：Funding was provided by the National Institute for Occupational Safety and Health of the Centers for Disease Control and Prevention(Grant.R01-OH-010297) 

主　　题：gas chromatography micro-GC microsystem mixtures sensor array VOCs 

摘      要：This report concerns a benchtop prototype instrument containing a gas chromatographic microanalytical system(μGC)designed for the selective determination of multiple airborne volatile organic compounds(VOCs)at concentrations in the vicinity of recommended occupational exposure *** core microsystem consists of a set of discrete Si-microfabricated devices:a dualcavity,adsorbent-packed micro-preconcentrator-focuser(μPCF)chip that quantitatively captures and thermally desorbs/injects VOCs with vapor pressures between~0.03 and 13 kPa;tandem micro-column(μcolumn)chips with cross-linked PDMS wall-coated stationary phases capable of temperature-programmed separations;and an integrated array of fiveμchemiresistors(μCR)coated with different thiolate-monolayer protected gold nanoparticle(MPN)interface films that quantifies and further differentiates among the analytes by virtue of the response patterns *** key components include a pre-trap for low-volatility interferences,a split-flow injection valve,and an onboard He carrier–gas *** assembled unit measures 19×30×14 cm,weighs~3.5 kg,operates on AC power,and is laptop/LabVIEW ***-and system-level tests of performance demonstrated injection bandwidths o1 s,aμcolumn capacity of≥8μg injected mass,linear calibration curves,no humidity effects,excellent medium-term(that is,1 week)reproducibility,autonomous operation for 8 h,detection limits below Threshold Limit Values(TLV)for 10 mL air samples collected in 1 min,and response patterns that enhanced vapor *** determination of a 17-VOC mixture in the presence of seven interferences was performed in 4 *** augur well for adapting the microsystem to an all-MEMS wearableμGC currently under parallel development.