检索结果-南通市图书馆

International Journal of Minerals,Metallurgy and Materials 2024年第10期31卷 2233-2243页

作者： Guonan Ma Shize Zhu Dong Wang Peng Xue BolüXiao Zongyi Ma Shi-changxu Innovation center for Advanced Materials Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China Centre of excellence for Advanced Materials Dongguan 523808China

A high-zinc composite,12vol%SiC/Al-13.3 Zn-3.27 Mg-1.07Cu(wt%),with an ultra-high-strength of 781 MPa was success-fully fabricated through a powder metallurgy method,followed by an extrusion *** effects of solid-solution and aging heat treat-ments on the microstructure and mechanical properties of the composite were extensively *** with a single-stage sol-id-solution treatment,a two-stage solid-solution treatment(470℃/1 h+480℃/1 h)exhibited a more effective solid-solution strengthen-ing owing to the higher degree of solid-solution and a more uniform *** to the aging hardness curves of the com-posite,the optimized aging parameter(100℃/22 h)was *** the aging temperature and time resulted in finer and more uniform nanoscale precipitates but only yielded a marginal increase in tensile *** fractography analysis revealed that intergranu-lar cracking and interface debonding were the main fracture mechanisms in the ultra-high-strength SiC/Al-Zn-Mg-Cu *** regions,such as the SiC/Al interface containing numerous compounds and the precipitate-free zones at the high-angle grain boundaries,were identified as significant factors limiting the strength enhancement of the *** compounds,including MgO,MgZn2,and Cu5Zn8,reduced the interfacial bonding strength,leading to interfacial debonding.

关键词： metal matrix composites heat treatment interfacial reaction mechanical properties fracture mechanism

Platelet-to-neutrophil ratio predicts hemorrhagic transformation and unfavorable outcomes in acute ischemic stroke with intravenous thrombolysis

在线全文

学校读者我要写书评

暂无评论

World Journal of Experimental Medicine 2024年第3期14卷 80-89页

作者： Ausanee Chaiwisitkun Sombat Muengtaweepongsa center of excellence in Stroke Faculty of MedicineThammasat UniversityKlonglaung 12120Pathum ThaniThailand

BACKGROUND Acute ischemic stroke(AIS)retains a notable stance in global disease burden,with thrombolysis via recombinant tissue plasminogen activator(rtPA)serving as a viable management approach,albeit with variable outcomes and the potential for complications like hemorrhagic transformation(HT).The platelet-to-neutrophil ratio(P/NR)has been considered for its potential prognostic value in AIS,yet its capacity to predict outcomes following rtPA administration demands further *** To elucidate the prognostic utility of P/NR in predicting HT and clinical outcomes following intravenous rtPA administration in AIS *** Data from 418 AIS patients treated with intravenous rtPA at Thammasat University Hospital from January 2018 to June 2021 were retrospectively *** relationship between P/NR and clinical outcomes[early neurological deterioration(E-ND),HT,delayed ND(D-ND),and 3-mo outcomes]was *** Notable variables,such as age,diabetes,and stroke history,exhibited statistical disparities when comparing patients with and without E-ND,HT,D-ND,and 3-mo outcomes.P/NR prognostication revealed an optimal cutoff of 43.4 with a 60.3%sensitivity and a 52.5%specificity for 90-d outcomes.P/NR prognostic accuracy was statistically significant for 90-d outcomes[area under the curve(AUC)=0.562],D-ND(AUC=0.584),and HT(AUC=0.607).CONCLUSION P/NR demonstrated an association with adverse 3-mo clinical outcomes,HT,and D-ND in AIS patients post-rtPA administration,indicating its potential as a predictive tool for complications and *** infers that a diminished P/NR may serve as a novel prognostic indicator,assisting clinicians in identifying AIS patients at elevated risk for unfavorable outcomes following rtPA therapy.

关键词： Acute ischemic stroke Platelet-to-neutrophil ratio Prognosis Hemorrhagic transformation Recombinant tissue plasminogen activator Thrombolysis Clinical outcomes

Jurassic integrative stratigraphy,biotas,and paleogeographical evolution of the Qinghai-Tibetan Plateau and its surrounding areas

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Earth Sciences 2024年第4期67卷 1195-1228页

作者： Jianguo LI Xin RAO Lin MU Xiaohui CUI Xin LI Hui LUO Peixue LIU center for excellence in Life and Paleoenvironment Nanjing Institute of Geology and PalaeontologyChinese Academy of SciencesNanjing 210008China Nanjing College University of Chinese Academy of SciencesNanjing 211135China

The Qinghai-Tibetan Plateau experienced a unique geological evolution during the Jurassic,driven by the termination of the Palaeotethys and the reduction of the *** Indian Plate separated from the northern margin of Gondwana and drifted northward from the Southern *** that the timing of strata serves as the basis for reconstructing geological history,the present work aimed to develop a new multiple stratigraphic and chronologic framework for the Jurassic strata of the Qinghai-Tibetan Plateau region via a synthesis of the material on lithostratigraphy,palaeontology,iso-radiometric dating,magnetostratigraphy,and other techniques with an emphasis on recent progress and *** new framework included the Jurassic System from the four major subdivisions of the plateau:the Baryan Har,Qiangtang,Lhasa-Gandise,and Southern Xizang(Himalaya).Ultimately,a more complete,refined biostratigraphic sequence was proposed,comprising the most common fossils in the plateau and those that are stratigraphically significant for the Jurassic stratigraphy,including ammonites,bivalves,brachiopods,foraminifera,radiolarians,and dinoflagellate cysts for the marine strata,and pollen and spores,and charophytes for the terrestrial *** biostratigraphic framework was correlated with the Jurassic international standard zonation of the Geological Time Scale 2020 via standard or representative species or genera of *** on this framework,we constructed a lateral correlation of the Jurassic strata between different basins of the *** palaeontologic correlation in the present work shows that the Lhasa-Gandise Block had a closer relationship with the Qiangtang Block than with the Southern Xizang Himalaya during the Jurassic ***,the Lhasa-Gandise Block and Qiangtang Block shared similar marine fauna features of the north marginal East *** contrasts the opinion suggesting that the Yarlung Zangbo Tethys was a small back-arc basin.A c

关键词： Biostratigraphy Chronostratigraphy Correlation Yarlung Zangbo suture Bangong Co-Nujiang suture Tethys

Modern phenomics to empower holistic crop science, agronomy, and breeding research

在线全文

学校读者我要写书评

暂无评论

Journal of Genetics and Genomics 2024年第8期51卷 790-800页

作者： Ni Jiang Xin-Guang Zhu Institute of Genetics and Developmental Biology Chinese Academy of SciencesBeijing 100101China center of excellence for Molecular Plant Sciences Chinese Academy of SciencesShanghai 200032China

Crop phenomics enables the collection of diverse plant traits for a large number of samples along different time scales,representing a greater data collection throughput compared with traditional *** modern crop phenomics use different sensors to collect reflective,emitted,and fluorescence signals,etc.,from plant organs at different spatial and temporal *** multi-modal,high-dimensional data not only accelerates basic research on crop physiology,genetics,and whole plant systems modeling,but also supports the optimization of field agronomic practices,internal environments of plant factories,and ultimately crop *** challenges and opportunities facing the current crop phenomics research community include developing community consensus or standards for data collection,management,sharing,and processing,developing capabilities to measure physiological parameters,and enabling farmers and breeders to effectively use phenomics in the field to directly support agricultural production.

关键词： Crop phenomics High-throughput phenotyping Traits Crop designer breeding Agronomy

Chemical vapor deposition for perovskite solar cells and modules

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Semiconductors 2024年第4期45卷 1-4页

作者： Zhihao Tao Yuxuan Song Baochang Wang Guoqing Tong Liming Ding School of Materials Science and Engineering Hefei University of TechnologyHefei 230009China center for excellence in Nanoscience(CAS) Key Laboratory of Nanosystem and Hierarchical Fabrication(CAS)National Center for Nanoscience and TechnologyBeijing 100190China

Metal halide perovskites are promising materials for solar cells because of high power conversion efficiency(PCE),tun-able bandgap,high defect tolerance,long carrier diffusion length,and low-cost fabrication[1-7].The PCE for perovskite solar cells(PSCs)reaches 26.14%for single-junction cells,29.1%for perovskite/perovskite tandem cells and 33.9%for perovskite/silicon tandem cells,being comparable to that for silicon and other thin-film solar cells[8-10].Perovskite solar cells have been made by solution methods including spin-coat-ing,blade coating and printing[11,12].

关键词： perovskite blade film

How plants sense and respond to osmotic stress

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Plant Biology 2024年第3期66卷 394-423页

作者： Bo Yu Dai-Yin Chao Yang Zhao Shanghai center for Plant Stress Biology CAS Center for Excellence in Molecular Plant SciencesThe Chinese Academy of SciencesShanghai 200032China Key Laboratory of Plant Carbon Capture The Chinese Academy of SciencesShanghai 200032China National Key Laboratory of Plant Molecular Genetics CAS Center for Excellence in Molecular Plant SciencesInstitute of Plant Physiology and EcologyThe Chinese Academy of SciencesShanghai 200032China University of Chinese Academy of Sciences Beijing 100049China

Drought is one of the most serious abiotic stresses to land *** sense and respond to drought stress to survive under water *** have studied how plants sense drought stress,or osmotic stress caused by drought,ever since Charles Darwin,and gradually obtained clues about osmotic stress sensing and signaling in *** stress is a physical stimulus that triggers many physiological changes at the cellular level,including changes in turgor,cell wall stiffness and integrity,membrane tension,and cell fluid volume,and plants may sense some of these stimuli and trigger downstream *** this review,we emphasized water potential and movements in organisms,compared putative signal inputs in cell wall-containing and cell wall-free organisms,prospected how plants sense changes in turgor,membrane tension,and cell fluid volume under osmotic stress according to advances in plants,animals,yeasts,and bacteria,summarized multilevel biochemical and physiological signal outputs,such as plasma membrane nanodomain formation,membrane water permeability,root hydrotropism,root halotropism,Casparian strip and suberin lamellae,and finally proposed a hypothesis that osmotic stress responses are likely to be a cocktail of signaling mediated by multiple *** also discussed the core scientific questions,provided perspective about the future directions in this field,and highlighted the importance of robust and smart root systems and efficient source-sink allocations for generating future high-yield stress-resistant crops and plants.

关键词： cell volume drought membrane tension osmotic stress turgor

Enrichment of ER tubule-derived microsomes by differential centrifugation and immunoprecipitation

在线全文

学校读者我要写书评

暂无评论

Biophysics Reports 2024年第2期10卷 61-66页

作者： Yiduo Liu Junjie Hu Bing Yan National Laboratory of Biomacromolecules CAS Center for Excellence in Biomacromolecules Institute of Biophysics Chinese Academy of Sciences University of Chinese Academy of Sciences

The endoplasmic reticulum(ER) is an essential component of the endomembrane system in eukaryotes and plays a crucial role in protein and lipid synthesis, as well as the maintenance of calcium homeostasis. Morphologically, the ER is composed primarily of sheets and tubules. The tubular ER is composed of a network of tubular membrane structures, each with diameters ranging from 30 to 50nanometers. In recent years, there has been in-depth research on the molecular mechanisms of membrane shaping and membrane fusion of the tubular ER. However, there is still limited understanding of the specific physiological functions of the tubular ER. Here, we report a protocol that combines differential centrifugation and immunoprecipitation to specifically enrich microsomes originating from the tubular ER in yeast. The ER tubule-derived microsomes can be further used for proteomic and lipidomic studies or other biochemical analyses.

关键词： Endoplasmic reticulum Microsome Differential centrifugation Immunoprecipitation

Supported Recyclable Metal-free Frustrated Lewis Pair Catalyst for Catalytic Hydrogenation of Substituted Pyridines to Piperidines

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2024年第4期40卷 682-689页

作者： MA Shaohua TANG Zhiyong CAS Key Laboratory for Nanosystem and Hierarchical Fabrication CAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing100190P.R.China University of Chinese Academy of Sciences Beijing100049P.R.China

The construction of heterogeneous frustrated Lewis pairs(FLPs)catalysts is crucial for realizing highly efficient and recyclable pyridines catalytic *** this work,we prepared a recyclable heterogenous FLPs catalyst CMP-BF with conjugated microporous polymer CMP-ethynyl as the support via self-catalyzed 1,1-carboboration reaction with commercial Lewis acid B(C_(6)F_(5))_(3).The as-synthesized CMP-BF demonstrates superior heterogenous catalytic hydrogenation performance(conversion>99%),and considerable stability(84%conversion after three cycles)in recyclable hydrogenation of 2,*** work provides insights into the fabrication and catalytic application of recyclable heterogenous FLP catalysts.

关键词： Pyridine hydrogenation Frustrated Lewis pair Conjugated microporous polymer

China's new ethical guidelines for the use of brain±computer interfaces

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

National Science Review 2024年第4期 7-8页

作者： Mu-ming Poo Institute of Neuroscience CAS Center for Excellence in Brain Science and Intelligence Technology NSR

While the world is bewildered by the dazzling advances of generative artificial intelligence and struggling to find consensual guidelines for its governance, the rapid pace of research on the brain–computer interface (BCI) also calls for governance on its development and application. In early February, China’s Ministry of Science and Technology (Mo ST) announced the ‘Guidelines for Research Ethics in Brain-computer Interface’[1] based on recommendations of the National Research Ethics Committee. Its content is largely in line with an earlier announcement in October 2023 by the Psychiatry Society of China [2] on ‘Ethics Governance of Brain-Computer Interface Research in Mental Disorders’. Both guidelines are formulated on the principles of the World Medical Association Declaration of Helsinki on ‘Ethical Principles for Medical Research Involving Human Subjects’in 2008.

关键词：

Nano-sized stationary phase packings retained by single-particle frit for microchip liquid chromatography

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第4期35卷 486-489页

作者： Wangyan Hu Ke Li Xiangnan Dou Ning Li Xiayan Wang center excellence for Environmental Safety and Biological Effects Beijing Key Laboratory for Green Catalysis and SeparationDepartment of ChemistryBeijing University of TechnologyBeijing 100124China center for Environmental Metrology National Institute of MetrologyBeijing 100029China

Modern chromatography is increasingly focused on miniaturization and integration. Compared to conventional liquid chromatography, microfluidic chip liquid chromatography(microchip-LC) has the potential due to its zero-dead volume connection and ease of integration. Nano-sized packings have the potential to significantly enhance separation performance in microchip-LC. However, their application has been hindered by packing difficulties. This study presents a method for packing nano-sized silica particles into a microchannel as the stationary phase. The microchip-LC packed column was prepared by combining the weir and the porous silica single-particle as frit to retain the packing particles. A surface tensionbased single-particle picking technique was established to insert porous single-particle frit into glass microchannels. Additionally, we developed a slurry packing method that utilizes air pressure to inject nano-sized packing into the microchannel. Pressure-driven chromatographic separation was performed using this nano-packed column integrated into a glass microchip. The mixture of four PAHs was successfully separated within just 8 min using a 5 mm separation channel length, achieving high theoretical plates(10~6plates/m). Overall, these findings demonstrate the potential of utilizing nano-sized packings for enhancing chromatographic performance in microchip systems.

关键词： Nano-size packing Single-particle frit Packed column Microchip LC Chromatographic separation