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Epidemiological and clinical features,treatment status,and economic burden of traumatic spinal cord injury in China:a hospital-based retrospective study

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Neural Regeneration Research 2024年第5期19卷 1126-1132页

作者： Hengxing Zhou Yongfu Lou Lingxiao Chen Yi Kang Lu Liu Zhiwei Cai David BAnderson Wei Wang Chi Zhang Jinghua Wang Guangzhi Ning Yanzheng Gao Baorong He Wenyuan Ding Yisheng Wang Wei Mei Yueming Song Yue Zhou Maosheng Xia Huan Wang Jie Zhao Guoyong Yin Tao Zhang Feng Jing Rusen Zhu Bin Meng Li Duan Zhongmin Zhang Desheng Wu Zhengdong Cai Lin Huang Zhanhai Yin Kainan Li Shibao Lu Shiqing Feng Department of Orthopedics The Second HospitalCheeloo College of MedicineShandong UniversityShandongChina Department of Orthopedics Shandong University Center for OrthopedicsQilu HospitalCheeloo College of MedicineShandong UniversityShandongChina Department of Orthopedics Tianjin Medical University General HospitalInternational Science and Technology Cooperation Base of Spinal Cord InjuryTianjin Key Laboratory of Spine and Spinal CordTianjinChina Faculty of Medicine and health The Back Pain Research TeamSydney Musculoskeletal HealthThe Kolling InstituteUniversity of SydneySydneyNSWAustralia Department of Spine Surgery Honghui HospitalXi’an Jiaotong UniversityXi’anShaanxi ProvinceChina Department of Burns and Plastic Surgery The Fourth Medical Center of Chinese PLA General HospitalBeijingChina Faculty of Medicine and health School of Health SciencesUniversity of SydneyNSWAustralia Sydney Spine Institute BurwoodSydneyNSWAustralia Laboratory of Epidemiology Tianjin Neurological InstituteDepartment of NeurologyTianjin Medical University General Hospital&Tianjin Neurological InstituteKey Laboratory of Post-Neuroinjury Neuro-repair and Regeneration in Central Nervous SystemMinistry of Education and Tianjin CityTianjinChina Department of Orthopedics Henan Provincial People’s HospitalZhengzhouHenan ProvinceChina Department of Spinal Surgery The Third Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Department of Orthopedics The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan ProvinceChina Department of Spine Surgery Zhengzhou Orthopedics HospitalZhengzhouHenan ProvinceChina Department of Orthopedic Surgery and Orthopedic Research Institute West China HospitalSichuan UniversityChengduSichuan ProvinceChina Department of Orthopedics Xinqiao HospitalArmy Medical UniversityChongqingChina Department of Orthopedics The First Affiliated Hospital of China Medical UniversityShenyangLiaoning ProvinceChina Department of Spinal Surgery Shengj

Traumatic spinal cord injury is potentially catastrophic and can lead to permanent disability or even death.China has the largest population of patients with traumatic spinal cord injury.Previous studies of traumatic spinal cord injury in China have mostly been regional in scope;national-level studies have been rare.To the best of our knowledge,no national-level study of treatment status and economic burden has been performed.This retrospective study aimed to examine the epidemiological and clinical features,treatment status,and economic burden of traumatic spinal cord injury in China at the national level.We included 13,465 traumatic spinal cord injury patients who were injured between January 2013 and December 2018 and treated in 30 hospitals in 11 provinces/municipalities representing all geographical divisions of China.Patient epidemiological and clinical features,treatment status,and total and daily costs were recorded.Trends in the percentage of traumatic spinal cord injuries among all hospitalized patients and among patients hospitalized in the orthopedic department and cost of care were assessed by annual percentage change using the Joinpoint Regression Program.The percentage of traumatic spinal cord injuries among all hospitalized patients and among patients hospitalized in the orthopedic department did not significantly change overall(annual percentage change,-0.5%and 2.1%,respectively).A total of 10,053(74.7%)patients underwent surgery.Only 2.8%of patients who underwent surgery did so within 24 hours of injury.A total of 2005(14.9%)patients were treated with high-dose(≥500 mg)methylprednisolone sodium succinate/methylprednisolone(MPSS/MP);615(4.6%)received it within 8 hours.The total cost for acute traumatic spinal cord injury decreased over the study period(-4.7%),while daily cost did not significantly change(1.0%increase).Our findings indicate that public health initiatives should aim at improving hospitals’ability to complete early surgery within 24 hours,which is associated with improved sensorimot

关键词： China clinical features costs epidemiology methylprednisolone sodium succinate methylprednisolone retrospective study traumatic spinal cord injury treatment

A Brief Talk on How to Promote China health and Quarantine at Points of Entry in the Framework of Global health

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口岸卫生控制 2018年第4期23卷 1-7,14页

作者：王晓中黄琳于畅臧宇婷 Dalian Customs(Pro-liaoning Entry-Exit Inspection and Quarantine Bureau) Dalian Friendship Hospital liaoning international travel health care center

Global health concerns about the health of the global population and the concepts of global health are gradually being accepted by all of the countries in the world.China health and quarantine at points of entry(POEs) is an integral part of global health,and its duty of prevention and control of the communicable diseases in POEs is consistent with the duty of global health to promote the health of global population.Under the principle of "prevention first",health and quarantine organ carries out the work of disease prevention and control and international travel health care,the reinforcement of core capacity at POEs,and focuses on human rights protection.All the same,there are some gaps with the requirements of global health,such as the inadequate of health promotion planning capacity,ethics awareness and legal protection.The future work of health and quarantine should change ideas on communicable diseases prevention at POEs,focus more on ethical consideration,and should optimize system architecture and human resources,strengthen cooperation,maintain core capacity at POEs,thus to build points of entry public health system with Chinese characteristics,meanwhile to apply the concepts of global health deeply into every aspects of health and quarantine at POEs.

关键词： global health health and quarantine POEs communicable disease core capacity

Pulmonary embolism excluded acute coronary syndrome by coronarography： a retrospective analysis

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Chinese Medical Journal 2012年第16期125卷 2867-2872页

作者： LIU Chun-ping LI Jun-xia NIU Li-li CHEN Hang-wei TAN Bo WANG Ya-ping Dep rtment of Cardiology Department of Respiratory Medicine General Hospitalof Beijing Military Command Beijing 100700 China Department ot Cardiology Department of Respiratory Medicine General Hospital of Beijing Military Command Beijing 100700 China international travel health care center Urumqi Xinjiang 830000China

Background Pulmonary embolism （PE） is often mistaken as acute coronary syndromes （ACS） because of the considerable overlap in their clinical features. We evaluated the factors causing misdiagnosis of PE as ACS and factors that differentiate PE from ACS to improve the diagnosis efficacy of PE. Methods The medical records of 22 consecutive PE patients, between 2001 and 2010, who were initially suspected of ACS were retrieved. ACS was ruled out by coronary artery angiography before a definite diagnosis of PE was given. Twenty-two contemporary cases of ACS matched by age and sex were recruited as controls. Clinical manifestations, electrocardiograms （ECG）, and biomarkers of these patients were reviewed retrospectively. The factors causing misdiagnosis of PE as ACS and factors differentiating PE from ACS were evaluated. Results We found two leading causes of misdiagnosis of PE as ACS. One is that PE can resemble ACS in several clinical aspects （symptoms and signs, ECG findings, plasma cardiac troponin I, and D-dimer）. The other is the insufficient recognition of PE by clinicians. Risk factors for venous thromboemboiism （VTE）, especially deep venous thrombosis （DVT）, together with signs of PE, such as unexplained dyspnea or hypoxemia, and right ventricular pressure overload on ECGs are valuable in differentiating the two diseases. Conclusions Differentiation between PE and ACS is sometimes challenging. Adequate awareness of the risk factors for VTE and the signs of PE are crucial in the diagnosis of PE.

关键词： pulmonary embolism, misdiagnosis acute coronary syndromes

氢氧化钠溶液吸收硫酰氟的传质反应动力学（英文）

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2014年第7期15卷 540-546页

作者： Yong NIE Xiao-jiang LIANG Mei-zhen LU Feng-wen YU Da-yong GU Min MIN Jian-bing JI College of Chemical Engineering Zhejiang University of Technology Shenzhen international travel health care center center for Biorefining and Department of Bioproducts and Biosystems Engineering University of Minnesota

研究目的:确定氢氧化钠溶液化学吸收硫酰氟的传质反应动力学区域,建立增强因子模型。研究方法:研究气液传质测定设备双搅拌釜中氢氧化钠溶液化学吸收硫酰氟的过程,并结合实验研究与理论分析建立了增强因子模型。重要结论:基于氢氧化钠... 详细信息

研究目的:确定氢氧化钠溶液化学吸收硫酰氟的传质反应动力学区域,建立增强因子模型。研究方法:研究气液传质测定设备双搅拌釜中氢氧化钠溶液化学吸收硫酰氟的过程,并结合实验研究与理论分析建立了增强因子模型。重要结论:基于氢氧化钠溶液化学吸收硫酰氟过程的实验研究,确定了氢氧化钠溶液化学吸收硫酰氟的传质反应动力学区域为快速拟一级反应。得到了298 K下其二级反应速率常数为1.44 m3/(mol·s),并建立了增强因子模型E=68.08CBL1/2,为脱除熏蒸后残留硫酰氟的工业化应用提供了理论依据。

关键词：硫酰氟氢氧化钠传质反应动力学化学吸收双搅拌釜

HIV,HCV,and HBV Co-Infections in a Rural Area of Shanxi Province with a History of Commercial Blood Donation

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Biomedical and Environmental Sciences 2011年第3期24卷 207-213页

作者： DONG RuiLing QIAO Xiao Chun JIA WangQian WONG Michelle QIAN HanZhu ZHENG XiWen XING WenGe LAI ShengHan WU ZhengLai JIANG Yan WANG Ning Shenzhen international travel health care center Shenzhen 518033 Guangdong China National center for AIDS/STD Control and Prevention Chinese Center for Disease Control and Prevention Beijing 102206 China Shanxi Provincial center for Disease Control and Prevention Taiyuan 030012 Shanxi China Wenxi County center for Disease Control and Prevention Wenxi 043800 Shanxi China School of Medicine Vanderbilt University Nashville TN USA Johns Hopkins Medical School New York USA Peking Union Medical College Beijing 100005 China

Background： Unhygienic blood collection in the early 1990s led to blood-borne infections in Central China. This study aimed to estimate human immunodeficiency virus （HIV） co-infection with hepatitis C and B viruses （HCV and HBV） and their risk factors in a rural area of Shanxi Province with a history of commercial blood donation. Methods： A cross-sectional study was conducted in 2004. All adult residents in the target area were invited to participate in the study. Face-to-face interviews were completed and blood specimens were tested for HIV, HCV, and HBV surface antigen （HBsAg）. Results： Prevalence rates of HIV, HCV, and HBsAg were 1.3% （40/3 062）, 12.7% （389/3 062）, and 3.5% （103/2982）, respectively. Of the 40 HIV-positive specimens, 85% were HCV positive and 2.5% were HBsAg positive. The history of commercial blood donation was positively associated with HIV, HCV, and HIV/HCV co-infections, but was negatively associated with HBsAg seropositivity. Migration for employment in the last 5 years was positively related to HIV, HBsAg, and HIV/HCV co-infections. Univariate logistic analysis showed that illegal drug use, number of sex partners, extramarital sex behavior, commercial sex behavior, and condom use rate were not related to anti-HIV, anti-HCV, HBsAg seropositivity or their co-infections. Conclusion： The history of commercial blood donation was the main risk factor for HIV, HCV, and HIV/HCV co-infections in this former commercial blood donation area. HIV and HCV prevention and treatment interventions are important in this area.

关键词： Human immunodeficiency Virus Co-infections Hepatitis C Virus Hepatitis B Virus SurfaceAntigen Commercial Blood Donation

Nutrients Deficiency and Excess Phenomena of Cut Rose and Their Physiological Significances

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Plant Diseases and Pests 2014年第4期5卷 20-25页

作者： Jin Xingzi Li Ming Jin Muzi Yang Jin College of Life Science Inner Mongolia University Vocational and Technical College Inner Mongolia Agricultural University Inner Mongolia international travel health care center

On the basis of a brief introduction of essential major dements and trace dements for cut rose, the physiological effect and deficiency and excess phenomena of major elements including nitrogen, phosphorus, potassium, magnesium, calcium, sulfur and trace dements including zinc, molybdenum, boron, iron, manganese, copper were mainly described; the main factors influencing nutrients absorption of cut rose were summarized, in order to provide a reference for the reasonable fertilization of cut rese.

关键词： Cut rose Physiological effect Deficiency symptoms Excess phenomenon Influence factors

Study on the interaction between polymorphisms of FOXO3A gene and environmental factors in longevity at Bama county,Guangxi province

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广西医科大学学报 2017年第11期34卷 1541-1545页

作者： Bingshuang Long Min He Xiangjuan Li Jian Qin Zhiyong Zhang Department of Occupational health and Department of Environmental health College of Public HealthGuangxi Medical UniversityNanningGuangxi 530021China Guangxi international travel health care center NanningGuangxi 530021China

Objective: To study the interaction between the polymorphisms of FOXO3A and the environmental factors in the longevity district of Bama county.Methods: Using Taqmaq probe,genotyping of FOXO3A gene was performed for 200 longevous elderly(aged 90-110)and 288 healthy controls(aged 48-89).The interaction between the polymorphisms of gene and environmental factors were analyzed by using conditional logistic regression.Results: Minor allele frequencies(MAF)of five known SNPs in FOXO3A gene were higher in cases than in controls(P<0.05).There was a positive interction between minority alleles of rs2764264 in FOXO3A gene and the environment factors in the longevity district(OR=11.08,γ=1.075).Conclusion: Five SNPs of FOXO3A gene would be closely correlated with human longevity in Bama.The interaction between the polymorphisms of FOXO3A genes rs2764264 and the environment factors in the longevity district had synergy to longevity.The longevity phenomenon in Bama probably was the result of the interaction between gene and environmental factors.

关键词：基因多态性环境因素临床分析医学研究

The Frequency of Infectious Diseases in Manzhouli Port from 2012 to 2014

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Advances in Infectious Diseases 2016年第1期6卷 1-6页

作者： Kepeng Xin Xuesong Chen Hua Deng Yi Li Qihui Zhang Muzi Jin Yun Li Juan Sun Manzhouli Entry-Exit Inspection and Quarantine Bureau Manzhouli China Manzhouli international travel healthcare center Manzhouli China Inner Mongolia international travel healthcare center Hohhot China Inner Mongolia health Supervision Hohhot China Inner Mongolia Medical University Hohhot China

The aim of this study was to determine the frequency of infectious diseases among people entering/exiting via Manzhouli port. We analyzed infectious disease data from the Manzhouli international travel health care center covering 2012 through 2014, as well as performed several laboratory tests to measure rates of infection. The frequencies of infectious diseases as well as their association with occupation and year of occurrence were calculated for people entering and exiting via the port. The total proportion of infectious diseases measured was 2.18%. Hepatitis B was the most commonly occurring at 1.68%, followed by syphilis, hepatits C and HIV, which were 0.23%, 0.21% and 0.04%, respectively. Contract workers, traffic staff, foreigners and those married abroad were more likely to be infected. Furthermore, there were significant differences among three years. Strategies should be developed and preventive policies should be implemented aimed at protecting the at risk populations at Manzhouli port, especially with regard to contract workers, traffic staff, foreigners and those married abroad.

关键词： Infectious Disease Detection Rate Entry/Exit Screening Occupation Manzhouli Port

Re-emergence of Ebola virus disease in Uganda:Should Southeast Asia countries be worried?

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Journal of Safety Science and Resilience 2023年第3期4卷 262-264页

作者： Haruna Muhammad Daiyab Farouq Muhammad Dayyab Department of Medicine Murtala Mohammed Specialist HospitalKanoNigeria Cardiac Intensive care Unit Mohammed Bin KhalifaBin Salman Al Khalifa Cardiac CenterAwaliBahrain

An outbreak of Ebola virus disease(EVD)(Sudan virus)was first reported in the Republic of Uganda on September 20,2022.As of November 17,2022,151 confirmed cases have been reported,including 55 deaths(with a case fatality rate among confirmed cases of 39%).During the EVD outbreak in 2013–2016,international travel played a significant role in the spread of the disease across national borders.During that time,several tasks requiring improvement were identified in the World health Organization(WHO)Southeast Asia Region(SEAR),including inadequate risk communication and risk assessment,data management gaps for surveillance purposes,inadequate capacity in molecular diagnostic techniques,lack of adequate planning for a surge of cases,and inadequate isolation rooms.It is therefore recommended that all countries of the WHO SEAR revisit their level of Ebola preparedness and address existing gaps.The emergence and rapid global spread of coronavirus disease 2019(COVID-19)have reiterated that the world has become a global village.This was confirmed by the spread of the monkeypox virus with cases reported in the WHO SEAR.Therefore,given the weak health infrastructure in the region,complacency could wreak havoc on the healthcare system if another epidemic emerges without an adequate level of preparedness.

关键词： Ebola Uganda Southeast Asia Outbreak