Epidemiological and clinical features,treatment status,and economic burden of traumatic spinal cord injury in China:a hospital-based retrospective study

作     者：Hengxing Zhou Yongfu Lou Lingxiao Chen Yi Kang Lu Liu Zhiwei Cai David BAnderson Wei Wang Chi Zhang Jinghua Wang Guangzhi Ning Yanzheng Gao Baorong He Wenyuan Ding Yisheng Wang Wei Mei Yueming Song Yue Zhou Maosheng Xia Huan Wang Jie Zhao Guoyong Yin Tao Zhang Feng Jing Rusen Zhu Bin Meng Li Duan Zhongmin Zhang Desheng Wu Zhengdong Cai Lin Huang Zhanhai Yin Kainan Li Shibao Lu Shiqing Feng Hengxing Zhou;Yongfu Lou;Lingxiao Chen;Yi Kang;Lu Liu;Zhiwei Cai;David B.Anderson;Wei Wang;Chi Zhang;Jinghua Wang;Guangzhi Ning;Yanzheng Gao;Baorong He;Wenyuan Ding;Yisheng Wang;Wei Mei;Yueming Song;Yue Zhou;Maosheng Xia;Huan Wang;Jie Zhao;Guoyong Yin;Tao Zhang;Feng Jing;Rusen Zhu;Bin Meng;Li Duan;Zhongmin Zhang;Desheng Wu;Zhengdong Cai;Lin Huang;Zhanhai Yin;Kainan Li;Shibao Lu;Shiqing Feng

作者机构：Department of OrthopedicsThe Second HospitalCheeloo College of MedicineShandong UniversityShandongChina Department of OrthopedicsShandong University Center for OrthopedicsQilu HospitalCheeloo College of MedicineShandong UniversityShandongChina Department of OrthopedicsTianjin Medical University General HospitalInternational Science and Technology Cooperation Base of Spinal Cord InjuryTianjin Key Laboratory of Spine and Spinal CordTianjinChina Faculty of Medicine and HealthThe Back Pain Research TeamSydney Musculoskeletal HealthThe Kolling InstituteUniversity of SydneySydneyNSWAustralia Department of Spine SurgeryHonghui HospitalXi’an Jiaotong UniversityXi’anShaanxi ProvinceChina Department of Burns and Plastic SurgeryThe Fourth Medical Center of Chinese PLA General HospitalBeijingChina Faculty of Medicine and HealthSchool of Health SciencesUniversity of SydneyNSWAustralia Sydney Spine InstituteBurwoodSydneyNSWAustralia Laboratory of EpidemiologyTianjin Neurological InstituteDepartment of NeurologyTianjin Medical University General Hospital&Tianjin Neurological InstituteKey Laboratory of Post-Neuroinjury Neuro-repair and Regeneration in Central Nervous SystemMinistry of Education and Tianjin CityTianjinChina Department of OrthopedicsHenan Provincial People’s HospitalZhengzhouHenan ProvinceChina Department of Spinal SurgeryThe Third Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Department of OrthopedicsThe First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan ProvinceChina Department of Spine SurgeryZhengzhou Orthopedics HospitalZhengzhouHenan ProvinceChina Department of Orthopedic Surgery and Orthopedic Research InstituteWest China HospitalSichuan UniversityChengduSichuan ProvinceChina Department of OrthopedicsXinqiao HospitalArmy Medical UniversityChongqingChina Department of OrthopedicsThe First Affiliated Hospital of China Medical UniversityShenyangLiaoning ProvinceChina Department of Spinal SurgeryShengjing Hospital of China Medical UniversityShenyangLiaoning ProvinceChina Shanghai Key Laboratory of Orthopedic ImplantsDepartment of Orthopedic SurgeryShanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of OrthopedicsThe First Affiliated Hospital of Nanjing Medical UniversityNanjingJiangsu ProvinceChina Department of Spinal SurgeryShanghai Jiao Tong University Affiliated Sixth People’s HospitalShanghaiChina Department of Spinal SurgeryTianjin HospitalTianjinChina Department of Spine SurgeryTianjin Union Medical CenterTianjinChina Department of Orthopedic SurgeryThe First Affiliated Hospital of Soochow UniversitySuzhouJiangsu ProvinceChina Department of OrthopedicsShenzhen Intelligent Orthopedics and Biomedical Innovation PlatformGuangdong Artificial Intelligence Biomedical Innovation PlatformShenzhen Second People’s HospitalThe First Affiliated Hospital of Shenzhen University Health Science CenterShenzhenGuangdong ProvinceChina Department of OrthopedicsThe Third Affiliated Hospital of Southern Medical UniversityGuangzhouGuangdong ProvinceChina Department of Spine SurgeryShanghai East Hospital Affiliated to Tongji University School of MedicineShanghaiChina Department of OrthopedicsShanghai General HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of OrthopedicsSun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Department of OrthopedicsThe First Affiliated HospitalXi’an Jiaotong UniversityXi’anShaanxi ProvinceChina Department of Orthopedic SurgeryAffiliated Hospital of Chengdu UniversityChengduSichuan ProvinceChina Department of OrthopedicsBeijing Xuanwu HospitalCapital Medical UniversityBeijingChina National Geriatric Diseases Research CenterBeijingChina 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2024年第19卷第5期

页      面：1126-1132页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

基　　金：supported by the National Key Research and Development Project No.2019YFA0112100(to SF) 

主　　题：China clinical features costs epidemiology methylprednisolone sodium succinate methylprednisolone retrospective study traumatic spinal cord injury treatment 

摘      要：Traumatic spinal cord injury is potentially catastrophic and can lead to permanent disability or even *** has the largest population of patients with traumatic spinal cord *** studies of traumatic spinal cord injury in China have mostly been regional in scope;national-level studies have been *** the best of our knowledge,no national-level study of treatment status and economic burden has been *** retrospective study aimed to examine the epidemiological and clinical features,treatment status,and economic burden of traumatic spinal cord injury in China at the national *** included 13,465 traumatic spinal cord injury patients who were injured between January 2013 and December 2018 and treated in 30 hospitals in 11 provinces/municipalities representing all geographical divisions of *** epidemiological and clinical features,treatment status,and total and daily costs were *** in the percentage of traumatic spinal cord injuries among all hospitalized patients and among patients hospitalized in the orthopedic department and cost of care were assessed by annual percentage change using the Joinpoint Regression *** percentage of traumatic spinal cord injuries among all hospitalized patients and among patients hospitalized in the orthopedic department did not significantly change overall(annual percentage change,-0.5%and 2.1%,respectively).A total of 10,053(74.7%)patients underwent *** 2.8%of patients who underwent surgery did so within 24 hours of injury.A total of 2005(14.9%)patients were treated with high-dose(≥500 mg)methylprednisolone sodium succinate/methylprednisolone(MPSS/MP);615(4.6%)received it within 8 *** total cost for acute traumatic spinal cord injury decreased over the study period(-4.7%),while daily cost did not significantly change(1.0%increase).Our findings indicate that public health initiatives should aim at improving hospitals’ability to complete early surgery within 24 ho