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中国有色金属学会会刊：英文版 2003年第3期13卷 585-589页

作者：李松陈康华刘红卫黄兰萍张茁 State key laboratory for Powder metallurgy

In order to improve the stress corrosion cracking resistance of the weldable Al Zn Mg alloys with medium strength, the near solvus pre precipitation following high temperature solution treatment was performed on LC52 and 7039 aluminum alloys. The effect of the pre precipitation on the microstructure, age hardening and stress corrosion cracking of LC52 and 7039 alloy was investigated. The results show that the near solvus pre precipitation can be limited on grain boundary and can enhance the discontinuity of grain boundary precipitates. The stress corrosion cracking resistance of aged Al Zn Mg alloys can be improved with non deteriorated strength and plasticity via pre precipitation.

关键词： Al-Zn-Mg合金铝合金应力腐蚀断裂高温预沉淀机械性能

Effect of high-temperature pre-precipitation on microstructure and properties of 7055 aluminum alloy

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中国有色金属学会会刊：英文版 2003年第4期13卷 750-754页

作者：陈康华黄兰萍 State key laboratory for Powder metallurgy

The near solvus pre precipitation following higher temperature solution treatment was performed on 7055 aluminum alloy. The effect of the pre precipitation on the microstructure, age hardening and stress corrosion cracking of 7055 alloy was investigated. The optical and transmission electron microscopy results show that the near solvus pre precipitation can be limited to grain boundary and enhance the discontinuity of grain boundary precipitates in the sequent age. The stress corrosion cracking resistance of aged 7055 alloys could be improved with non deteriorated strength and plasticity via the pre precipitation.

关键词：铝合金高温预沉淀显微结构机械性能应力腐蚀断裂

Microwave strengthens decomposition of mixed rare earth concentrate: Microwave absorption characteristics

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Journal of Rare Earths 2019年第5期37卷 541-546页

作者： Yukun Huang Ting'an Zhang Zhihe Dou Guozhi Lv Guihong Han Weijun Peng School of Chemical Engineering and Energy Zhengzhou University laboratory of special metallurgy and Process Engineering School of Metallurgy Northeastern University

The potential application of microwave heating technology for processing the mixed rare earth concentrate was systematically investigated by analyzing the microwave absorption characteristics in this study. The complex permittivity was measured through resonant cavity perturbation method. The variations of permittivity, the loss factor, loss tangent and the penetration depth with the increasing temperature were investigated numerically. The results indicate that the permittivity increases as the temperature increases, and temperature has a pivotal effect on it. The mixed concentrate is high loss material at the temperature range from 600 to 800℃ according to theoretical analyses of loss tangent and penetration depth. The results of phase transition analysis prove that the variation of microwave absorption characteristics of mixed concentrate is caused by the changes of crystal and lattice *** reflectivity, loss factor and penetration depth of the mixed concentrate were also calculated, and the results indicate that processing the mixed concentrate by microwave heating is of high feasibility and industrial potential.

关键词： Microwave processing Microwave absorption characteristics Dielectric constant Loss tangent Mixed rare earth concentrate

Exercise preconditioning alleviates ischemia-induced memory deficits by increasing circulating adiponectin

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Neural Regeneration Research 2025年第5期20卷 1445-1454页

作者： Meifeng Zheng Borui Zhang Sonata S Y Yau Kwok-Fai So Li Zhang Haining Ou Department of Rehabilitation Medicine Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina Department of Rehabilitation Medicine The Fifth Clinical College of Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina key laboratory of CNS Regeneration(Ministry of Education) Guangdong-Hong Kong-Macao Institute of CNS RegenerationJinan UniversityGuangzhouGuangdong ProvinceChina Department of Rehabilitation Sciences The Hong Kong Polytechnic UniversityHong Kong Special Administrative RegionChina State key laboratory of Brain and Cognitive Science Li Ka Shing Faculty of MedicineThe University of Hong KongHong Kong Special Administrative RegionChina Center for Exercise and Brain Science School of PsychologyShanghai University of SportShanghaiChina Neuroscience and Neurorehabilitation Institute University of Health and Rehabilitation SciencesQingdaoShandong ProvinceChina

Cerebral ischemia is a major health risk that requires preventive approaches in addition to drug *** exercise enhances neurogenesis and synaptogenesis,and has been widely used for functional rehabilitation after *** this study,we determined whether exercise training before disease onset can alleviate the severity of cerebral *** also examined the role of exercise-induced circulating factors in these *** mice were subjected to 14 days of treadmill exercise training before surgery for middle cerebral artery *** found that this exercise pre-conditioning strategy effectively attenuated brain infarct area,inhibited gliogenesis,protected synaptic proteins,and improved novel object and spatial memory *** analysis showed that circulating adiponectin plays a critical role in these preventive effects of *** activation of adiponectin receptors by Adipo Ron mimicked the effects of exercise,while inhibiting receptor activation abolished the exercise *** summary,our results suggest a crucial role of circulating adiponectin in the effects of exercise pre-conditioning in protecting against cerebral ischemia and supporting the health benefits of exercise.

关键词： adiponectin cerebral ischemia exercise pre-conditioning hippocampus memory function middle cerebral artery occlusion prefrontal cortex synaptic proteins treadmill exercise

Non-haloaluminate ionic liquids for low-temperature electrodeposition of rare-earth metals—A review

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Journal of Rare Earths 2015年第10期33卷 1017-1025页

作者：张启波华一新徐存英李艳李坚董鹏 key laboratory of Ionic Liquids metallurgy Faculty of Metallurgical and Energy Engineering Kunming University of Science and Technology State key laboratory of Complex Nonferrous Metal Resources Cleaning Utilization in Yunnan Province

The inherent advantages of ionic liquids （ILs） in electrochemistry have received extensive attention in recent two decades. As a new generation of ILs, non-haloaluminate ILs exhibit better benefits and fewer drawbacks compared to haloaluminate based ILs, which are more qualified for metal electrodeposition, especially reactive metals. In this brief review, the recent developments regard- ing the application of non-haloaluminate ILs as solvents for low-temperature electrodeposition of rare-earth （RE） metals are outlined. In addition, the current problems and an outlook on future research are presented.

关键词： ionic liquids electrochemistry rare earths low-temperature electrodeposition

Investigation of pyrite surface state by DFT and AFM

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Journal of Central South University 2015年第7期22卷 2508-2514页

作者：先永骏聂琪文书明刘建邓久帅 Faculty of Land Resource Engineering kunming University of Science and Technology State key laboratory of Complex Nonferrous Metal Resources Clean Utilization (kunming University of Science and Technology) Faculty of Mining Engineering kunming metallurgy College

The surface states of pyrite(Fe S2) were theoretically investigated using first principle calculation based on the density functional theory(DFT). The results indicate that both the(200) and(311) surfaces of pyrite undergo significant surface atom relaxation after geometry optimization, which results in a considerable distortion of the surface region. In the normal direction, i.e., perpendicular to the surface, S atoms in the first surface layer move outward from the bulk, while Fe atoms move toward the bulk, forming an S-rich surface. The surface relaxation processes are driven by electrostatic interaction, which is evidenced by a relative decrease in the surface energy after surface relaxation. Such a relaxation process is visually interpreted through the qualitative analysis of molecular mechanics. Atomic force microscopy(AFM) analysis reveals that only sulfur atom is visible on the pyrite surface. This result is consistent with the DFT data. Such S-rich surface has important influence on the flotation properties of pyrite.

关键词： pyrite density functional theory(DFT) surface energy surface relaxation S-rich surface

Effect of slag on oxide inclusions in carburized bearing steel during industrial electroslag remelting

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International Journal of Minerals,metallurgy and Materials 2019年第3期26卷 291-300页

作者： Shi-jian Li Guo-guang Cheng Zhi-qi Miao Lie Chen Xin-yan Jiang State key laboratory of Advanced metallurgy University of Science and Technology Beijing Xining special Steel Group Co. Ltd.

Industrial experiments with three types of slags were performed to investigate the effect of slag on oxide inclusions during electroslag remelting(ESR) process. G20CrNi2Mo bearing steel was used as the consumable electrode and remelted using a 2400-kg industrial furnace. The results showed that most inclusions in the electrode were low-melting-point CaO-MgO-Al_2O_3. After ESR, all the inclusions in ingots were located outside the liquid region. When the slag consisted of 65.70 wt% CaF_2, 28.58 wt% Al_2O_3, and 4.42 wt% CaO was used, pure Al_2O_3 were the dominant inclusions in ingot, some of which presented a clear trend of agglomeration. When the ingot was remelted by a multi-component slag with 16.83 wt% CaO, a certain amount of sphere CaAl_4O_7 inclusions larger than 5 μm were generated in ingot. The slag with 8.18 wt% CaO exhibited greater capacity to control the inclusion characteristics. Thermodynamic calculations indicated that the total Ca and Mg in ingots were attributed from the relics in electrode and strongly influenced by the slag composition. The formation of ingot inclusions was calculated by FactSage^(TM) 7.0, and the results were basically in accordance with the observed inclusions, indicating that a quasi-thermodynamic equilibrium could be obtained in the metal pool.

关键词： bearing steel electroslag remelting slag inclusions thermodynamics

Design of a submerged entry nozzle for optimizing continuous casting of stainless steel slab

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Journal of Iron and Steel Research International 2023年第11期30卷 2229-2241页

作者： Jia-chen Pang Guo-yu Qian Sheng Pang Wen-hui Ma Guo-guang Cheng School of metallurgy and Energy Engineering Kunming University of Science and TechnologyKunming650093YunnanChina CAS key laboratory of Green Process and Engineering Institute of Process EngineeringChinese Academy of SciencesBeijing100190China State key laboratory of Advanced metallurgy University of Science and Technology BeijingBeijing100083China

To solve slag entrapment and casting slab defects in the process of stainless steel continuous casting,submerged entry nozzle(SEN)for slab casters operating at casting speed of 1 m/min was developed based on 3D numerical simulation and water modeling experiments by controlling the outlet shape and angle of original SEN with oval and 15°angle outlet under current industrial *** simulations of fluid velocity at outlets with different shapes and angles of SENs have been carried *** results showed that oval outlet with 5°and 15°angle led to asymmetric rotating flow pattern at outlet,as well as square outlet with 15°angle,but symmetric flow pattern formed at square outlet with 5°*** effect of these SENs on meniscus stability,flow field and slag entrapment behavior of stainless steel slab casting mold was further studied by water modeling *** results showed that difficult floating fine droplets formed when the angle of outlet was 15°under the dual effect of vortex convection and shear force due to the strong swirling flow from outlet and rotating flow of ***,outlet with 5°angle could lead to the formation of larger slag droplets,while the oval outlet with 5°angle could result in the scour to the mold ***,the square outlet with 5°angle was a relatively ideal solution for the submerged entry nozzle from the aspects of the stability of the mold and the slag entrapment *** the design of a new SEN according to the experimental result,the solidification structure of continuous casting slab was obviously improved by industrial test.

关键词： Stainless steel Continuous casting Submerged entry nozzle Water modeling Slag entrapment

Effect of crystallization on purity of volatile metallic magnesium prepared from a one-step multi-region condensation process under vacuum condition

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Journal of Magnesium and Alloys 2022年第11期10卷 3281-3287页

作者： Bin Yang Dong Liang Neng Xiong Yang Tian Baoqiang Xu Yongnian Dai The State key laboratory of Complex Non-ferrous Metal Resources Clean Utilization Kunming University of Science and TechnologyKunming 650093China National Engineering laboratory for Vacuum metallurgy Kunming University of Science and TechnologyKunming 650093China Faculty of Metallurgical and Energy Engineering Kunming University of Science and TechnologyKunming 650093China IME Institute of Process metallurgy and Metal Recycling RWTH Aachen UniversityAachen 52056Germany

We hereby report a green and simple volatilization-condensation process to prepare high-purity magnesium in different crystal forms under vacuum condition. This method can be also used for the analysis of other metals, which can be separated by the same concept. In addition, Mg condensation is a very fast process, and the corresponding easy growth of the Mg crystals is promoted when the concentration of magnesium vapor is raised. From the view of crystallization, ultrafast crystal growth of high-purity magnesium is a barrier-free and orderly process. Interestingly, different condensed forms of Mg obtained via this ultrafast volatilization-condensation process are showing different purities. The distinct morphological formation of Mg in different condensed form is probably attributed to the differences of surface energy change of Mg during the condensation process.

关键词： Mg Purity Vacuum Condensation Crystallization

Single-cell omics: experimental workflow, data analyses and applications

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Science China Life Sciences 2025年第1期68卷 5-102页

作者： Fengying Sun Haoyan Li Dongqing Sun Shaliu Fu Lei Gu Xin Shao Qinqin Wang Xin Dong Bin Duan Feiyang Xing Jun Wu Minmin Xiao Fangqing Zhao Jing-Dong J.Han Qi Liu Xiaohui Fan Chen Li Chenfei Wang Tieliu Shi Department of Clinical laboratory the Affiliated Wuhu Hospital of East China Normal University (The Second People's Hospital of Wuhu City) Pharmaceutical Informatics Institute College of Pharmaceutical SciencesZhejiang University key laboratory of Spine and Spinal Cord Injury Repair and Regeneration (Tongji University) Ministry of EducationOrthopaedic DepartmentTongji HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Frontier Science Center for Stem Cells School of Life Sciences and TechnologyTongji University Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine Shanghai East HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Research Institute of Intelligent Computing Zhejiang Lab Shanghai Research Institute for Intelligent Autonomous Systems Center for Single-cell Omics School of Public HealthShanghai Jiao Tong University School of Medicine National key laboratory of Chinese Medicine Modernization Innovation Center of Yangtze River DeltaZhejiang University Center for Bioinformatics and Computational Biology Shanghai Key Laboratory of Regulatory Biologythe Institute of Biomedical Sciences and School of Life SciencesEast China Normal University Beijing Institutes of Life Science Chinese Academy of Sciences Peking-Tsinghua Center for Life Sciences Academy for Advanced Interdisciplinary StudiesCenter for Quantitative Biology (CQB)Peking University Zhejiang key laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases Women's HospitalZhejiang University School of Medicine key laboratory of Advanced Theory and Application in Statistics and Data Science-MOE School of StatisticsEast China Normal University

Cells are the fundamental units of biological systems and exhibit unique development trajectories and molecular features. Our exploration of how the genomes orchestrate the formation and maintenance of each cell, and control the cellular phenotypes of various organismsis, is both captivating and intricate. Since the inception of the first single-cell RNA technology, technologies related to single-cell sequencing have experienced rapid advancements in recent years. These technologies have expanded horizontally to include single-cell genome, epigenome,proteome, and metabolome, while vertically, they have progressed to integrate multiple omics data and incorporate additional information such as spatial sc RNA-seq and CRISPR screening. Single-cell omics represent a groundbreaking advancement in the biomedical field,offering profound insights into the understanding of complex diseases, including cancers. Here, we comprehensively summarize recent advances in single-cell omics technologies, with a specific focus on the methodology section. This overview aims to guide researchers in selecting appropriate methods for single-cell sequencing and related data analysis.

关键词： single-cell sequencing genome epigenome proteomics metabolomics multimodal spatial transcriptomics CRISPR screening