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Hypoglycemic Effect of Radix Et Rhizoma Salviae Miltiorrhizae,Guixi Green Tea and Their Compatibility on Mice

Medicinal Plant 2024年第3期15卷 53-55,70页

作者： Chen YANG Zhaohui HUANG Liqing TANG Wenjing HUANG Danyu CHEN Rujun SHI Suoyi HUANG Lixiang LU Shiyou ZHOU School of Clinical medicine Youjiang Medical University for NationalitiesBaise 533000China School of Pharmacy Youjiang Medical University for NationalitiesBaise 533000China key laboratory of Research on Characteristic Ethnic medicine in the youjiang river basin of guangxi Colleges and universities Baise 533000China

[Objectives]To explore the hypoglycemic effect of Radix Et Rhizoma Salviae Miltiorrhizae,Guixi green tea and their compatibility on mice,so as to provide more options for the adjuvant treatment of diabetes and improve the comprehensive utilization value of Guixi green tea.[Methods]After being fed adaptively for 7 d,60 SPF-grade male mice were intraperitoneally injected with alloxouracil(180 mg/kg)to induce hyperglycemia model,from which 35 mice with a successful model were *** were randomly divided into 5 groups(Danshen group,green tea group,compatible group,positive control group and blank control group),with 7 animals in each *** mice in all groups were administered according to the dose of 200 mg/kg once a day for 15 *** the last administration,their body weight was measured on the 15 th day after fasting for 12 h,and their fasting blood glucose was measured by tail clipping.[Results]After modeling,the mice in each group showed typical hyperglycemia symptoms,namely obvious polydipsia,polyphagia,polyuria and weight *** with the blank control group,Danshen group and green tea group had obvious hypoglycemic effect(P<0.05),and compatible group had significant hypoglycemic effect(P<0.01).Compared with the blank control group,the weight loss of diabetic mice could also be inhibited in green tea group and compatible group(P<0.05).[Conclusions]Danshen,Guixi green tea and their compatibility had the effect of lowering blood sugar,among which the compatible group had the most obvious effect.

关键词： Salvia miltiorrhiza Guixi green tea Compatibility Blood sugar

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Stomatal dynamics are regulated by leaf hydraulic traits and guard cell anatomy in nine true mangrove species

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Plant Diversity 2024年第3期46卷 395-405页

作者： Ya-Dong Qie Qi-Wei Zhang Scott A.M.McAdam Kun-Fang Cao State key laboratory for Conservation and Utilization of Subtropical Agro-Bioresources College of ForestryGuangxi UniversityNanning 530004China guangxi key laboratory of Forest Ecology and Conservation College of ForestryGuangxi UniversityNanning 530004China key laboratory of Ecology of Rare and Endangered Species and Environmental Protection Ministry of EducationGuangxi Normal UniversityGuilin 541001China guangxi key laboratory of Landscape Resources Conservation and Sustainable Utilization in Lijiang river basin Guangxi Normal UniversityGuilin 541001China Purdue Center for Plant Biology Department of Botany and Plant PathologyPurdue UniversityWest LafayetteIN 47907USA

Stomatal regulation is critical for mangroves to survive in the hyper-saline intertidal zone where water stress is severe and water availability is highly ***,very little is known about the stomatal sensitivity to vapour pressure deficit(VPD)in mangroves,and its co-ordination with stomatal morphology and leaf hydraulic *** measured the stomatal response to a step increase in VPD in situ,stomatal anatomy,leaf hydraulic vulnerability and pressure-volume traits in nine true mangrove species of five families and collected the data of genome *** aimed to answer two questions:(1)Does stomatal morphology influence stomatal dynamics in response to a high VPD in mangroves?with a consideration of possible influence of genome size on stomatal morphology;and(2)do leaf hydraulic traits influence stomatal sensitivity to VPD in mangroves?We found that the stomata of mangrove plants were highly sensitive to a step rise in VPD and the stomatal responses were directly affected by stomatal anatomy and hydraulic ***,denser stomata was correlated with faster stomatal closure at high VPD across the species of Rhizophoraceae,and stomata size negatively and vein density positively correlated with genome *** negative leaf osmotic pressure at the full turgor(πo)was related to higher operating steady-state stomatal conductance(gs);and a higher leaf capacitance(Cleaf)and more embolism resistant leaf xylem were associated with slower stomatal responses to an increase in *** addition,stomatal responsiveness to VPD was indirectly affected by leaf morphological traits,which were affected by site salinity and consequently leaf water *** results demonstrate that mangroves display a unique relationship between genome size,stomatal size and vein packing,and that stomatal responsiveness to VPD is regulated by leaf hydraulic traits and stomatal *** work provides a quantitative framework to better understand of stomatal regulation in mangroves

关键词： Stomatal temporal kinetics Vapour-pressure deficit(VPD) Leaf water relations Leaf hydraulic vulnerability Leaf osmotic potential Genome size

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Correlation between Combined Urinary Metal Exposure and Grip Strength under Three Statistical Models:A Cross-sectional Study in Rural guangxi

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Biomedical and Environmental Sciences 2024年第1期37卷 3-18页

作者： LIANG Yu Jian RONG Jia Hui WANG Xue Xiu CAI Jian Sheng QIN Li Dong LIU Qiu Mei TANG Xu MO Xiao Ting WEI Yan Fei LIN Yin Xia HUANG Shen Xiang LUO Ting Yu GOU Ruo Yu CAO Jie Jing HUANG Chu Wu LU Yu Fu QIN Jian ZHANG Zhi Yong Department of Environmental and Occupational Health School of Public HealthGuangxi Medical UniversityNanning 530021GuangxiChina key laboratory of Tumor Immunology and Microenvironmental Regulation Guilin Medical UniversityGuilin 541199GuangxiChina Department of Environmental Health and Occupational medicine School of Public HealthGuilin Medical UniversityGuilin 541199GuangxiChina guangxi Colleges and universities key laboratory of Prevention and Control of Highly Prevalent Diseases Guangxi Medical UniversityNanning 530021GuangxiChina guangxi key laboratory of Environment and Health Research Guangxi Medical UniversityNanning 530021GuangxiChina key laboratory of Longevity and Aging-related Diseases of Chinese Ministry of Education Guangxi Medical UniversityNanning 530021GuangxiChina guangxi Health Commission key laboratory of Entire Lifecycle Health and Care Guilin Medical UniversityGuilin 541199GuangxiChina

Objective This study aimed to investigate the potential relationship between urinary metals copper(Cu),arsenic(As),strontium(Sr),barium(Ba),iron(Fe),lead(Pb)and manganese(Mn)and grip *** We used linear regression models,quantile g-computation and Bayesian kernel machine regression(BKMR)to assess the relationship between metals and grip *** In the multimetal linear regression,Cu(β=−2.119),As(β=−1.318),Sr(β=−2.480),Ba(β=0.781),Fe(β=1.130)and Mn(β=−0.404)were significantly correlated with grip strength(P<0.05).The results of the quantile g-computation showed that the risk of occurrence of grip strength reduction was−1.007(95%confidence interval:−1.362,−0.652;P<0.001)when each quartile of the mixture of the seven metals was *** kernel function regression model analysis showed that mixtures of the seven metals had a negative overall effect on grip strength,with Cu,As and Sr being negatively associated with grip strength *** the total population,potential interactions were observed between As and Mn and between Cu and Mn(P_(interactions) of 0.003 and 0.018,respectively).Conclusion In summary,this study suggests that combined exposure to metal mixtures is negatively associated with grip ***,Sr and As were negatively correlated with grip strength levels,and there were potential interactions between As and Mn and between Cu and Mn.

关键词： Urinary metals Handgrip strength Quantile g-computation Bayesian kernel machine regression

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Effects of Polygala fallax Hemsl Water Extract on a Mouse Model of Gastric Motility Disorders

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Medicinal Plant 2024年第4期15卷 101-106页

作者： Liangyin ZHU Xiaofeng HAO Liuqi HUANG Zongyuan CHEN Wenfeng CHEN Liu YANG Bingchen HUANG Liyuan LI Aipeng LI Suoyi HUANG Xiuzhen SU School of Clinical medicine Youjiang Medical University for NationalitiesBaise 533000China key laboratory of guangxi universities on national medicine in youjiang river Youjiang Medical University for NationalitiesBaise 533000China School of Pharmacy Youjiang Medical University for NationalitiesBaise 533000China Institute of Life Sciences Youjiang Medical University for NationalitiesBaise 533000China

[Objectives]To explore the effects of Polygona fallax Hemsl water extract on gastrointestinal motility in normal mice and gastric motility disorder model mice and approximate mechanism.[Methods]Using normal mice and mice with gastric motility disorders(modeled with atropine),the effects of different mass concentration groups of *** Hemsl water extract(0.125,0.250,0.500 g/mL)and domperidone groups on gastric residual rate,small intestine propulsion rate,serum motilin(MLT),vasoactive intestinal peptide(VIP),and tissue morphology were studied.[Results]There was a highly significant difference(P<0.01)in the small intestine propulsion rate of liquid in normal mice among the different concentration groups of *** Hemsl water extract compared to the blank *** small intestine propulsion rate and gastric residue rate of semi-solid paste were statistically significant compared to the blank group(P<0.05).Among them,there was a highly significant difference between the high concentration group(67.75%±7.65%,46.5%±10.62%)and the medium concentration group(60.90%±5.87%,59.27%±7.82%)(P<0.01).There was statistical significance in normal mouse serum MLT content in the high concentration group(P<0.05).There was no effect on serum VIP levels in normal mice;no effect on the morphology of stomach and intestinal tissues of normal *** small intestine propulsion rate and gastric residue rate of liquid and semi-solid paste in mice with gastric motility disorders were statistically significant compared to the atropine group,with extremely significant differences(P<0.01).[Conclusions]*** Hemsl water extract has a promoting effect on gastrointestinal *** of the specific mechanisms by which *** Hemsl promotes gastrointestinal motility in normal mice may be related to the content of MLT in mouse *** mechanism of action in atropine induced gastric paresis mice may be related to the reactivation of M receptors,and the action mechanism of *** Hemsl d

关键词： Polygala fallax Hemsl Gastric motility Mouse model Gastric emptying Gastric paresis Motilin Vasoactive intestinal peptide

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Establishment and Evaluation of a Mouse Model of Allergic Rhinitis

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Medicinal Plant 2024年第4期15卷 111-113,121页

作者： Xiang QIN Yuan PAN Xiaoni PAN Yanfeng MO Shuwen LI Tingting XIE Lixiang LU Jiancheng LIANG Shiyou ZHOU Suoyi HUANG School of Clinical medicine Youjiang Medical University for NationalitiesBaise 533000China School of Public Health and Management Youjiang Medical University for NationalitiesBaise 533000China School of Pharmacy Youjiang Medical University for NationalitiesBaise 533000China key laboratory of Research on Characteristic Ethnic medicine in the youjiang river basin of guangxi Colleges and universities Baise 533000China

[Objectives]To explore a new method for induction of allergic rhinitis in mice,and compare and evaluate it with common modeling methods.[Methods]36 mice were randomly divided into the control group,blank group and experimental group,and there were 12 mice in each *** mice in the control group were conventionally *** is,the mice were first injected intraperitoneally with the mixture composed of OVA 50μg,[Al(OH)3]5 mg and 1ml of normal saline once every other day,and then since the 15 th d,20μL of 5%OVA solution was dropped into each nasal cavity once a day,which lasted for 7 *** blank group was treated with the same amount of normal saline according to the control group,and received intraperitoneal injection and bilateral nasal drip *** the experimental group,mice were first given intraperitoneal injection of the mixture composed of ovalbumin(OVA)75μg,aluminum hydroxide gel[Al(OH)3]8 mg and normal saline 1.5 mL for basic *** the 26 th d,20μL of 3%OVA solution was dropped into each nasal cavity once a day,which lasted for 10 *** number of sneezes,the number of nose scratching,the amount of nasal discharge,and the activity of mice in each group were observed,and the behavior of allergic reaction was ***,the number of eosinophils in the nasal discharge of mice and the IgE content in serum were measured.[Results]The score of nasal stimulation symptoms,the number of eosinophils and serum IgE level of mice in the control group and the experimental group were higher than those in the blank group(P0.05).[Conclusions]The modeling method was more suitable for the development of allergic rhinitis patients condition,and reduced the probability of death of mice due to modeling,and simplified the experimental operation.

关键词： Allergic rhinitis Mouse model Modeling effect

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Community structure and species diversity dynamics of a subtropical evergreen broad-leaved forest in China:2005 to 2020

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Plant Diversity 2024年第1期46卷 70-77页

作者： Shi-Guang Wei Lin Li Kun-Dong Bai Zhi-Feng Wen Jing-Gang Zhou Qin Lin key laboratory of Ecology of Rare and Endangered Species and Environmental Protection(guangxi Normal University) Ministry of EducationGuilin 541004GuangxiChina School of Life&Environmental Sciences Guilin University of Electronic TechnologyGuilin 541004GuangxiChina guangxi key laboratory of Landscape Resources Conservation and Sustainable Utilization in Lijiang river basin Guilin 541004GuangxiChina key laboratory of Vegetation Restoration and Management of South China Botanical Garden of Degraded Ecosystems Chinese Academy of SciencesGuangzhou 510650GuangdongChina Center of Plant Ecology Core Botanical GardensChinese Academy of SciencesGuangzhou 510650GuangdongChina

Here,we characterize the temporal and spatial dynamics of forest community structure and species diversity in a subtropical evergreen broad-leaved forest in *** found that community structure in this forest changed over a 15-year ***,renewal and death of common species was large,with the renewal of individuals mainly concentrated within a few populations,especially those of Aidia canthioides and Cryptocarya *** numbers of individual deaths for common species were concentrated in the small and mid-diameter *** spatial distribution of community species diversity fluctuated in each monitoring period,showing a more dispersed diversity after the 15-year study period,and the coefficient of variation on quadrats *** 2010,the death and renewal of the community and the spatial variation of species diversity were different compared to other survey *** weather may have affected species regeneration and community stability in our subtropical monsoon evergreen broad-leaved *** findings suggest that strengthening the monitoring and management of the forest community will help better understand the long-and short-term causes of dynamic fluctuations of community structure and species diversity,and reveal the factors that drive changes in community structure.

关键词： Community structure Death and renewal dynamics Species diversity dynamics South subtropical forest

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Temperature trends and its elevation-dependent warming over the Qilian Mountains

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Journal of Mountain Science 2024年第2期21卷 500-510页

作者： ZHAO Peng HE Zhibin MA Dengke WANG Wen QIAN Lihui School of Computer Science Huainan Normal UniversityHuainan 232038China Linze Inland river basin Research Station Key Laboratory of Inland River Basin ScienceNorthwest Institute of Eco-Environment and ResourceChinese Academy of SciencesLanzhou 730000China University of Chinese Academy of Sciences Beijing 100049China

Understanding temperature variability especially elevation dependent warming(EDW)in high-elevation mountain regions is critical for assessing the impacts of climate change on water resources including glacier melt,degradation of soils,and active layer *** means that temperature is warming faster with the increase of *** this study,we used observed temperature data during 1979-2017 from 23 meteorological stations in the Qilian Mountains(QLM)to analyze temperature trend with Mann-Kendall(MK)test and Sen’s slope *** showed that the warming trends for the annual temperature followed the order of T_min>T_mean>T_max and with a shift both occurred in *** and summer temperature have a higher increasing trend than that in autumn and winter.T_mean shifts occurred in 1996 for spring and summer,in 1997 for autumn and winter.T_max shifts occurred in 1997 for spring and 1996 for summer.T_min shifts occurred in 1997 for spring,summer and winter as well as in 1999 for *** mean diurnal temperature range(DTR)shows a significant decreasing trend(-0.18°C/10a)from 1979 to *** mean DTR shows a significant decreasing trend(-0.26°C/10a)from 1979 to 2017 with a shift occurred in *** removing longitude and latitude factors,we can learn that the warming enhancement rate of average annual temperature is 0.0673°C/km/10a,indicating that the temperature warming trend is accelerating with the continuous increase of *** increase rate of elevation temperature is 0.0371°C/km/10a in spring,0.0457°C/km/10a in summer,0.0707°C/km/10a in autumn,and 0.0606°C/km/10a in winter,which indicates that there is a clear EDW in the *** main causes of warming in the Qilian Mountains are human activities,cloudiness,ice-snow feedback and El Nino phenomenon.

关键词： Climate change Qilian Mountains Warming rates DTR Elevation-dependent warming

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Characteristics and Genesis of Acid Drainage Contamination from a Rock Tunneling Project Site

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Journal of Earth Science 2024年第1期35卷 190-200页

作者： Yanyun Li Zejiao Luo Shihua Qi Hubei key laboratory of Yangtze river basin Environmental Aquatic Science School of Environmental StudiesChina University of GeosciencesWuhan 430078China State key laboratory of Biogeology and Environmental Geology China University of GeosciencesWuhan 430078China

While acid mine drainage(AMD)issues have become a topic of global concern,few studies have focused on acid drainage problems of non-mining *** conducted field research and a series of laboratory experiments to investigate the characteristics,release processes and formation of acid drainage *** rock samples and adjacent surface water,groundwater,soil and sediment samples were collected at a railway tunnel construction site in central China,and various parameters,such as the p H,mineral ion concentrations,and heavy metal concentrations,were *** on the measured concentrations,surface water and sediments were seriously contaminated by acids,sulfate salts and heavy *** in surface water showed a decreasing tendency as the distance from the spoils increased,while that in sediments showed a greater influence of coprecipitation and adsorption processes of heavy metal *** eluviation experiments of three rock samples indicated that R2(silty fine sandstone)was the most likely major acid drainage *** ferrooxidans was cultured and isolated from contaminated water to study the oxidation conditions during the release *** significant release of acid drainage when air and bacteria were both in the culture container suggested that oxygen and bacteria were necessary to produce acid drainage from spoils.

关键词： acid mine drainage heavy metals leaching oxidation

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Intermittent disturbance mechanical behavior and fractional deterioration mechanical model of rock under complex true triaxial stress paths

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International Journal of Mining Science and Technology 2024年第1期34卷 117-136页

作者： Zhi Zheng Hongyu Xu Kai Zhang Guangliang Feng Qiang Zhang Yufei Zhao State key laboratory of Featured Metal Materials and Life-cycle Safety for Composite Structures Key Laboratory of Disaster Prevention and Structural Safety of Ministry of EducationCollege of Civil Engineering and ArchitectureGuangxi UniversityNanning 530004China State key laboratory of Geomechanics and Geotechnical Engineering Institute of Rock and Soil MechanicsChinese Academy of SciencesWuhan 430071China State key laboratory of Simulation and Regulation of Water Cycle in river basin China Institute of Water Resources and Hydropower ResearchBeijing 100080China State key laboratory for Geomechanics and Deep Underground Engineering China University of Mining and TechnologyXuzhou 221116China

Mechanical excavation,blasting,adjacent rockburst and fracture slip that occur during mining excavation impose dynamic loads on the rock mass,leading to further fracture of damaged surrounding rock in three-dimensional high-stress and even causing ***,a novel complex true triaxial static-dynamic combined loading method reflecting underground excavation damage and then frequent intermittent disturbance failure is *** triaxial static compression and intermittent disturbance tests are carried out on *** effects of intermediate principal stress and amplitude on the strength characteristics,deformation characteristics,failure characteristics,and precursors of monzogabbro are analyzed,intermediate principal stress and amplitude increase monzogabbro strength and tensile fracture *** increases in microseismic parameters during rock loading can be precursors for intermittent rock *** on the experimental result,the new damage fractional elements and method with considering crack initiation stress and crack unstable stress as initiation and acceleration condition of intermittent disturbance irreversible deformation are proposed.A novel three-dimensional disturbance fractional deterioration model considering the intermediate principal stress effect and intermittent disturbance damage effect is established,and the model predicted results align well with the experimental *** sensitivity of stress states and model parameters is further explored,and the intermittent disturbance behaviors at different f are *** study provides valuable theoretical bases for the stability analysis of deep mining engineering under dynamic loads.

关键词： True triaxial static and disturbance test Mechanical properties Failure mechanism and precursor Intermittent disturbance effect Fractional mechanical model

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Spatiotemporal characteristics and driving mechanisms of land use/land cover(LULC)changes in the Jinghe river basin,China

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Journal of Arid Land 2024年第1期16卷 91-109页

作者： WANG Yinping JIANG Rengui YANG Mingxiang XIE Jiancang ZHAO Yong LI Fawen LU Xixi State key laboratory of Eco-hydraulics in Northwest Arid Region of China Xi'an University of TechnologyXi'an 710048China State key laboratory of Simulation and Regulation of Water Cycle in river basin China Institute of Water Resources and Hydropower ResearchBeijing 100038China State key laboratory of Hydraulic Engineering Simulation and Safety Tianjin UniversityTianjin 300072China Department of Geography National University of SingaporeSingapore 117570Singapore

Understanding the trajectories and driving mechanisms behind land use/land cover(LULC)changes is essential for effective watershed planning and *** study quantified the net change,exchange,total change,and transfer rate of LULC in the Jinghe river basin(JRB),China using LULC data from 2000 to *** trajectory analysis,knowledge maps,chord diagrams,and standard deviation ellipse method,we examined the spatiotemporal characteristics of LULC *** further established an index system encompassing natural factors(digital elevation model(DEM),slope,aspect,and curvature),socio-economic factors(gross domestic product(GDP)and population),and accessibility factors(distance from railways,distance from highways,distance from water,and distance from residents)to investigate the driving mechanisms of LULC changes using factor detector and interaction detector in the geographical detector(Geodetector).The key findings indicate that from 2000 to 2020,the JRB experienced significant LULC changes,particularly for farmland,forest,and *** the study period,LULC change trajectories were categorized into stable,early-stage,late-stage,repeated,and continuous change *** the stable change type,the late-stage change type predominated the LULC change trajectories,comprising 83.31% of the total change *** period 2010-2020 witnessed more active LULC changes compared to the period *** LULC changes exhibited a discrete spatial expansion trend during 2000-2020,predominantly extending from southeast to northwest of the *** driving factors on LULC changes included slope,GDP,and distance from *** interaction detection results imply either bilinear or nonlinear enhancement for any two driving factors impacting the LULC changes from 2000 to *** comprehensive understanding of the spatiotemporal characteristics and driving mechanisms of LULC changes offers valuable insights for the planning and sustainable management

关键词： land use/land cover(LULC)changes driving mechanisms trajectory analysis geographical detector(Geodetector) Grain for Green Project Jinghe river basin

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