检索结果-南通市图书馆

MicroR-9c-5p and novel-mir50 co-target Akt to regulate Lasioderma serricorne reproduction

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Insect Science 2024年第1期31卷 106-118页

作者： Yi Yan Dong-Dong Qin Hong Yang Kang-Kang Xu Can Li Wen-Jia Yang provincial key laboratory for Agricultural Pest Management of Mountainous Region Institute of EntomologyGuizhou UniversityGuiyangChina Guizhou provincial key laboratory for Rare Animal and Economic Insect of the Mountainous Region College of Biology and Environmental EngineeringGuiyang UniversityGuiyangChina

High fecundity is a common characteristic of insect pests which increases the difficulty of population ***/threonine kinase Akt is an indispensable component of the insulin signaling *** of LsAkt severely hinders reproduction in Lasioderma serricorne,a stored product insect ***,the post-transcriptional pathway of LsAkt in *** remains *** study identified 2 binding sites of miR-9c-5p and novel-mir50 in the coding sequences of *** expression profiles of 2 microRNAs(miRNAs)and LsAkt displayed an opposite pattern during the adult *** reporter assay showed that novel-mir50 and miR-9c-5p could downregulate the expression of *** of miR-9c-5p and novel-mir50 by injection of mimics inhibited the expression of LsAkt and reduced oviposition,decreased egg hatchability,and blocked ovarian *** also decreased the expression of genes involved in ovarian development(LsVg and LsVgR)and the nutritional signaling pathway(LsTOR,LsS6K,and Ls4EBP),and reduced the phosphorylation of ***,injection of miR-9c-5p and novel-mir50 inhibitors induced the expressions of LsAkt,LsVg,LsVgR,LsTOR,LsS6K,and Ls4EBP,enhanced Akt phosphorylation level,and accelerated ovarian *** of bovine insulin downregulated the expression of miR-9c-5p and novel-mir50 and upregulated the LsAkt *** also rescued the reproductive development defects associated with miR-9c-5p/novel-mir50 overexpression,forming a positive regulatory loop of insulin *** results indicate that miR-9c-5p/novel-mir50 regulates the female reproduction of *** by targeting Akt in response to insulin *** data also demonstrate the effects of the insulin/miRNA/Akt regulatory axis in insect reproduction.

关键词： Akt insulin Lasioderma serricorne microRNA reproduction

High-precision alkali-atom density measurement and control methods using light absorption for dual-beam SERF magnetometers

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Optics Letters 2024年第5期22卷 41-46页

作者：刘子傲陆吉玺胡朝晖李晓昱闫一凡詹迪李建利 key laboratory of Ultra-Weak Magnetic Field Measurement Technology Ministry of EducationSchool of Instrumentation and Optoelectronic EngineeringBeihang UniversityBeijing 100191China Zhejiang provincial key laboratory of Ultra-Weak Magnetic-Field Space and Applied Technology Hangzhou Innovation InstituteBeihang UniversityHangzhou 310051China Hefei National laboratory Hefei 230088China Shen Yuan Honors College Beihang UniversityBeijing 100191China

The alkali-atom density measurement method based on light absorption is highly suitable for a spin-exchange relaxationfree(SERF)atomic magnetometer because of its high-precision measurement and complete nonmagnetic *** this study,the optical rotation angle detection system based on polarization balance detection is utilized to realize the alkali-atom density real-time measurement without affecting magnetic field *** discovered that there exists an optimal frequency detuning of the probe light,which offers the highest sensitivity in alkali-atom density measurement and the lowest susceptibility to temperature fluctuations in terms of the scale *** contrast to conventional light absorption measurements based on pump light,this method demonstrated a threefold improvement in alkali-atom density measurement sensitivity while remaining immune to ambient magnetic fields and incident light intensity ***,we utilized this method to achieve closed-loop temperature control with an accuracy of 0.04℃.

关键词： light absorption temperature measurement and control dual-beam SERF magnetometer

Single-cell transcriptomic analysis reveals transcript enrichment in oxidative phosphorylation,fluid sheer stress,and inflammatory pathways in obesity-related glomerulopathy

在线全文

学校读者我要写书评

暂无评论

Genes & Diseases 2024年第4期11卷 314-326页

作者： Yinyin Chen Yushun Gong Jia Zou Guoli Li Fan Zhang Yiya Yang Yumei Liang Wenni Dai Liyu He Hengcheng Lu Department of Nephrology Hunan Provincial People's HospitalThe First Affliated Hospital of Hunan Normal UniversityHunan Clinical Research Center for Chronic Kidney DiseaseChangshaHunan 410000China Department of Nephrology The Second Xiangya Hospital of Central South UniversityHunan Key Laboratory of Kidney Disease and Blood PurificationChangshaHunan 410011China Cardiovascular Research Institute of jiangxi Province Jiangxi Provincial People's HospitalThe First Affiliated Hospital of Nanchang Medical CollegeNanchangJiangxi 330006China

Obesity-related glomerulopathy(ORG)is an independent risk factor for chronic kid-ney disease and even progression to end-stage renal *** have been undertaken to elucidate the mechanisms underlying the development of ORG and substantial advances have been made in the treatment of ORG,but relatively little is known about cell-specific changes in gene *** define the transcriptomic landscape at single-cell resolution,we analyzed kidney samples from four patients with ORG and three obese control subjects without kidney disease using single-cell RNA *** report for the first time that immune cells,including T cells and B cells,are decreased in ORG *** analysis indicated that SPP1 was significantly up-regulated in T cells and B *** gene is related to inflammation and cell *** of differential gene expression in glomerular cells(endothelial cells,mesangial cells,and podocytes)showed that these cell types were mainly enriched in genes related to oxidative phosphorylation,cell adhesion,thermogenesis,and inflammatory pathways(PI3K-Akt signaling,MAPK signaling).Furthermore,we found that the podocytes of ORG patients were enriched in genes related to the fluid shear stress ***,an evaluation of cell-cell communications revealed that there were interactions between glomerular parietal epithelial cells and other cells in ORG patients,with major interactions between parietal epithelial cells and ***,our identification of molecular events,cell types,and differentially expressed genes may facilitate the development of new preventive or therapeutic approaches for ORG.

关键词： Fluid shear stress Inflammation Obesity-related glomerulopathy Oxidative phosphorylation Single-cell RNA seq

Investigation on damage mechanism of compressor blades in turboshaft engine induced by ice impacts at various locations

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Mechanica Sinica 2024年第7期40卷 181-194页

作者： Hao Niu Chao Li Anhua Chen Guangfu Bin Lun Long Hunan provincial key laboratory of Health Maintenance for Mechanical Equipment Hunan University of Science and TechnologyXiangtan 411201China AECC HAPRI key laboratory of Aero-engine Vibration Technology Zhuzhou 412000China

Ice causes impact damage to different positions of the compressor blade,destroys the structural integrity of the rotor structure,and then causes unbalanced failure and even causes nonlinear vibration accidents such as collision and friction,which affects the execution of helicopter *** investigate the influence of impact position on the damage form and dynamic response of blades during ice impact,a dynamic model by finite element-smooth particle fluid dynamic coupling method is *** ice impact damage experiment of the TC4 plate based on the air gun experimental platform was carried out to verify the reliability of the simulation *** damage of compressor blades impacted by ice from different positions under static and design speed of 45000 r/min is *** research results indicate that under static conditions,the damage caused by ice impact from the leading edge blade tip to the leading edge blade root first increases and then decreases,with the maximum damage occurring at the 66.7%blade height position on the leading *** the design speed,the closer the impact locations are to the leaf tip,the greater the damage is,and the plastic damage,equivalent stress,and kinetic energy loss of the ice impact are lower than the blade static *** research conclusion can provide theoretical reference and data support for the design of structural strength and protection of compressor blades in turboshaft engines.

关键词： Turboshaft engine Compressor blade Ice Impact damage simulation Dynamic response

Miniature tunable Airy beam optical meta-device

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Opto-Electronic Advances 2024年第2期7卷 5-12页

作者： Jing Cheng Zhang Mu Ku Chen Yubin Fan Qinmiao Chen Shufan Chen Jin Yao Xiaoyuan Liu Shumin Xiao Din Ping Tsai Department of Electrical Engineering City University of Hong KongKowloonHong Kong SAR 999077China State key laboratory of Terahertz and Millimeter Waves City University of Hong KongKowloonHong Kong SAR 999077China Centre for Biosystems Neuroscienceand NanotechnologyCity University of Hong KongKowloonHong Kong SAR 999077China Ministry of Industry and Information Technology key Lab of Micro-Nano optoelectronic Information System Guangdong Provincial Key Laboratory of Semiconductor Optoelectronic Materials and Intelligent Photonic SystemsHarbin Institute of TechnologyShenzhen 518055China

Tunable Airy beams with controllable propagation trajectories have sparked interest in various fields,such as optical manipulation and laser *** research approaches encounter challenges related to insufficient compactness and integration feasibility,or they require enhanced tunability to enable real-time dynamic manipulation of the propagation *** this work,we present a novel method that utilizes a dual metasurface system to surpass these limitations,significantly enhancing the practical potential of the Airy *** approach involves encoding a cubic phase profile and two off-axis Fresnel lens phase profiles across the two *** validity of the proposed strategy has been confirmed through simulation and experimental *** proposed meta-device addresses the existing limitations and lays the foundation for broadening the applicability of Airy beams across diverse domains,encompassing light-sheet microscopy,laser fabrication,optical tweezers,etc.

关键词： metasurface miniature device tunable Airy beam tunable meta-device

Ionic liquid-assisted preparation of hydroxyapatite and its catalytic performance for decarboxylation of itaconic acid

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Engineering 2024年第3期67卷 9-15页

作者： Shutong Pang Hualiang An Xinqiang Zhao Yanji Wang Hebei provincial key laboratory of Green Chemical Technology and Efficient Energy Saving Tianjin Key Laboratory of Chemical Process SafetySchool of Chemical Engineering and TechnologyHebei University of TechnologyTianjin 300130China

The synthesis of methacrylic acid from biomass-derived itaconic acid is a green route,for it can get rid of the dependence on fossil *** order to solve the problems on this route such as use of a preciousmetal catalyst and a corrosive homogeneous alkali,we prepared a series of hydroxyapatite catalysts by an ionic liquid-assisted hydrothermal method and evaluated their catalytic *** results showed that the ionic liquid[Bmim]BF_(4) can affect the crystal growth of hydroxyapatite,provide fluoride ion for fluorination of hydroxyapatite,and adjust the surface acidity and basicity,morphology,textural properties,crystallinity,and composition of ***[Bmim]BF4 dosage and hydrothermal temperature can affect the fluoride ion concentration in the hydrothermal system,thus changing the degree of fluoridation of *** fluoride-ion concentration can lead to the formation of CaF_(2) and thus significantly decrease the catalytic performance of *** hydrothermal time mainly affects the growth of hydroxyapatite crystals on the c axis,leading to different catalytic *** suitable conditions for the preparation of this fluoridized hydroxyapatite are as follows:a mass ratio of[Bmim]BF4 to calcium salt=0.2:1,a hydrothermal time of 12 h,and a hydrothermal temperature of 130℃.A maximal methacrylic acid yield of 54.7%was obtained using the fluoridized hydroxyapatite under relatively mild reaction conditions(250℃ and 2 MPa of N_(2))in the absence of a precious-metal catalyst and a corrosive homogeneous alkali.

关键词： Ionic liquid Hydroxyapatite Itaconic acid Methacrylic Decarboxylation reaction

Broadband,Polarization-Sensitive,and Self-Powered High-Performance Photodetection of Hetero-Integrated MoS_(2)on Lithium Niobate

在线全文

学校读者我要写书评

暂无评论

Research 2024年第2期2023卷 203-212页

作者： Zhigang He Heyuan Guan Xijie Liang Junteng Chen Manyan Xie Kaiwen Luo Ran An Liang Ma Fengkai Ma Tiefeng Yang Huihui Lu Guangdong provincial key laboratory of Optical Fiber Sensing and Communications Jinan UniversityGuangzhou 510632China key laboratory of optoelectronic Information and Sensing Technologies of Guangdong Higher Education Institutes Jinan UniversityGuangzhou 510632China institute of Fluid Physics China Academy of Engineering PhysicsMianyang 621900China College of Physics and Electronic Engineering Hengyang Normal UniversityHengyang 421008China

High-performance photodetectors hold promising potential in optical communication and imaging ***,conventional counterparts are suffering narrow detection range,high power consumption,and poor polarization *** originating from switchable polarization in ferroelectrics can be used to optimize the photo-to-electric procedure and improve the photodetection *** this regard,we constructed a configuration by integrating 2-dimensional molybdenum disulfide(MoS_(2))with ferroelectric lithium niobate(LiNbO_(3)),resulting in the MoS_(2)/LiNbO_(3)heterostructured *** from the pyroelectric effect of LiNbO_(3),the limitation of bandgap on the detection range can be broken,thus broadening the response band of the detector to 365 to 1,064 nm,as well as enabling the self-powered ***,high carrier mobility and decent light absorbance of MoS_(2)introduce robust light-matter interactions with the underlying LiNbO_(3),leading to ultrafast rise/fall times of≈150μs/250μs and switching ratios of up to≈***,the highest responsivity,specific detectivity,and external quantum efficiency achieved were 17.3 A·W^(-1),4.3×10^(11)Jones,and 4,645.78%,***,because of the anisotropy of the spontaneous-polarized LiNbO_(3)substrate,the photocurrent of the device achieved a dichroic ratio of 7.42,comparing favorably to most MoS_(2)-based *** work demonstrates the integration potential between ferroelectric LiNbO_(3)and 2-dimensional materials for high-performance photodetection.

关键词： polarization ferroelectric Polarization

Structural engineering of hard carbon through spark plasma sintering for enhanced sodium-ion storage

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rare Metals 2024年第9期43卷 4274-4285页

作者： Hao-Ming Xiao Heng Zheng Ping Yuan Jun-Hui Luo Lin-Lin Shen Jie-Feng Tan Xian-You Luo De Li Yong Chen Guangdong key laboratory for Hydrogen Energy Technologies School of Materials Science and Hydrogen EnergyFoshan University State key laboratory of Marine Resource Utilization in South China Sea Hainan Provincial Key Laboratory of Research on Utilization of Si-Zr-Ti ResourcesHainan University

Hard carbon （HC） has emerged as one of the superior anode materials for sodium-ion batteries （SIBs）,with its electrochemical performance significantly influenced by the presence of oxygen functional groups and its closed pore ***,current research on the structural adjustment of these oxygen functional groups and the closed pore architecture within HC remains ***,energy-efficient and contamination-free spark plasma sintering technology was employed to tune the structure of coconut-shell HC,resulting in significant adjustments to the content of carboxyl （decreasing from 5.71 at%to 2.12 at%） and hydroxyl groups （decreasing from 7.73 at % to 6.26 at%）.Crucially,these modifications reduced the irreversible reaction of oxygen functional groups with Na+.Simultaneously,a substantial number of closed pores with an average diameter of 1.22 nm were generated within the HC,offering an ideal environment for efficient Na+*** structural changes resulted in a remarkable improvement in the electrochemical performance of the modified *** reversible specific capacity of the modified HC surged from 73.89 mAh·g-1to an impressive 251.97 m Ah·g-1at a current density of 50 mA·*** at 400 mA·g-1,the reversible specific capacity increased significantly from 14.55 to 85.44 mAh·***,this study provides a novel perspective for designing tailored HC materials with the potential to develop high-performance SIBs.

关键词： Closed pores Hard carbon Oxygen functional groups Sodium-ion batteries Spark plasma sintering

Enhanced removal of antibiotic resistance genes during chicken manure composting after combined inoculation of Bacillus subtilis with biochar

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2024年第1期135卷 274-284页

作者： Zewen Wu Luan Zhang Hao Lin Shungui Zhou Fujian provincial key laboratory of Soil Environmental Health and Regulation College of Resources and EnvironmentFujian Agriculture and Forestry UniversityFuzhou 350002China School of Environmental Science and Engineering Hubei Key Laboratory of Mine Environmental Pollution Control and RemediationHubei Polytechnic UniversityHuangshi 435003China Fujian provincial key laboratory of Eco-Industrial Green Technology Wuyi UniversityWuyishan 354300China

This study explored the combined effects of Bacillus subtilis inoculation with biochar on the evolution of bacterial communities,antibiotic resistance genes(ARGs),and mobile genetic elements(MGEs)during the composting of chicken *** results showed that *** inoculation combined with biochar increased bacterial abundance and diversity as well as prolonged the compost thermophilic *** organic matter biodegradation and facilitated the organic waste compost humification process,reduced the proliferation of ARGs by altering the bacterial *** and Actinobacteriota were the main resistant bacteria related to ARGs and *** decrease in ARGs and MGEs was associated with the reduction in the abundance of related host *** inoculation with *** and the addition of biochar could promote nutrient transformation,reduce the increase in ARGs and MGEs,and increase the abundance of beneficial soil taxa.

关键词： Antibiotic resistance gene Bacillus subtilis Bacterial community Biochar Composting