检索结果-南通市图书馆

Zoological Research 2024年第4期45卷 821-830页

作者： Jing Zhang Yafei Chang Peng Zhang Yanqi Zhang Mengke Wei Chenyang Han Shun Wang Hui-Meng Lu Tiantian Cai Can Xie High Magnetic Field Laboratory Hefei Institutes of Physical ScienceChinese Academy of SciencesScience IslandHefeiAnhui 230031China science Island Branch of graduate School University of Science and Technology of ChinaHefeiAnhui 230036China institutes of Physical science and Information Technology Anhui UniversityHefeiAnhui 230039China School of Life sciences Key Laboratory for Space Bioscience and BiotechnologyNorthwestern Polytechnical UniversityXi’anShaanxi 710072China Institute of Quantum Sensing Zhejiang UniversityHangzhouZhejiang 310027China

Magnetic sense,or termed magnetoreception,has evolved in a broad range of taxa within the animal kingdom to facilitate orientation and ***,highly conserved A-type iron-sulfur proteins,are widely distributed across all phyla and play essential roles in both magnetoreception and iron-sulfur cluster ***,the evolutionary origins and functional diversification of MagRs from their prokaryotic ancestor remain *** this study,MagR sequences from 131 species,ranging from bacteria to humans,were selected for analysis,with 23 representative sequences covering species from prokaryotes to Mollusca,Arthropoda,Osteichthyes,Reptilia,Aves,and mammals chosen for protein expression and *** studies revealed a gradual increase in total iron content in MagRs during *** types of MagRs were identified,each with distinct iron and/or iron-sulfur cluster binding capacity and protein stability,indicating continuous expansion of the functional roles of MagRs during speciation and *** evolutionary biochemical study provides valuable insights into how evolution shapes the physical and chemical properties of biological molecules such as MagRs and how these properties influence the evolutionary trajectories of MagRs.

关键词： Magnetoreception Magnetoreceptor(MagR) Iron-sulfur cluster Stability Evolutionary biochemistry

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Rotating magnetic field inhibits Aβ protein aggregation and alleviates cognitive impairment in Alzheimer’s disease mice

引用

Zoological Research 2024年第4期45卷 924-936页

作者： Ruo-Wen Guo Wen-Jing Xie Biao Yu Chao Song Xin-Miao Ji Xin-Yu Wang Mei Zhang Xin Zhang High Magnetic Field Laboratory CAS Key Laboratory of High Magnetic Field and Ion Beam Physical BiologyHefei Institutes of Physical ScienceChinese Academy of SciencesHefeiAnhui 230031China science Island Branch of graduate School University of Science and Technology of ChinaHefeiAnhui 230036China institutes of Physical science and Information Technology Anhui UniversityHefeiAnhui 230601China School of Life sciences Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui 230026China

Amyloid beta(Aβ)monomers aggregate to form fibrils and amyloid plaques,which are critical mechanisms in the pathogenesis of Alzheimer’s disease(AD).Given the important role of Aβ1-42 aggregation in plaque formation,leading to brain lesions and cognitive impairment,numerous studies have aimed to reduce Aβaggregation and slow AD *** diphenylalanine(FF)sequence is critical for amyloid aggregation,and magnetic fields can affect peptide alignment due to the diamagnetic anisotropy of aromatic *** this study,we examined the effects of a moderate-intensity rotating magnetic field(RMF)on Aβaggregation and AD *** indicated that the RMF directly inhibited Aβamyloid fibril formation and reduced Aβ-induced cytotoxicity in neural cells in *** the AD mouse model APP/PS1,RMF restored motor abilities to healthy control levels and significantly alleviated cognitive impairments,including exploration and spatial and non-spatial memory *** examinations demonstrated that RMF reduced amyloid plaque accumulation,attenuated microglial activation,and reduced oxidative stress in the APP/PS1 mouse *** findings suggest that RMF holds considerable potential as a non-invasive,high-penetration physical approach for AD treatment.

关键词： lzheimer’s disease Rotating magnetic field Amyloid-β Cognitive function Alzheimer’s disease animal models

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Origin of the near-room temperature resistance transition in lutetium with H2/N2 gas mixture under high pressure

引用

National science Review 2024年第07期 26-32页

作者： Di Peng Qiaoshi Zeng Fujun Lan Zhenfang Xing Zhidan Zeng Xiaoxing Ke Yang Ding Ho-kwang Mao Key Laboratory of Materials Physics Institute of Solid State Physics Hefei Institutes of Physical Science(HFIPS)Chinese Academy of Sciences science Island Branch Graduate School of University of Science and Technology of China Center for High Pressure science and Technology Advanced Research Shanghai Key Laboratory of Material Frontiers Research in Extreme Environments(MFree) Shanghai Advanced Research in Physical Sciences(SHARPS) State Key Laboratory of Superhard Materials Institute of PhysicsJilin University College of Materials science&Engineering Beijing University of Technology

The recent report of room-temperature superconductivity at near-ambient pressure in nitrogen-doped lutetium hydride（Lu-H-N） by Dasenbrock-Gammon et al. [Nature 615, 244–250（2023）] has attracted tremendous attention due to its anticipated great impact on technology. However, the results could not be independently reproduced by other groups worldwide in follow-up studies, which elicited intense controversy. Here, we develop a reliable experimental protocol to minimize the extensively concerned extrinsic influences on the sample by starting the reaction from pure lutetium loaded with an H2/N2gas mixture in a diamond anvil cell under different pressures and temperatures and simultaneously monitoring the entire chemical reaction process using in situ four-probe resistance measurements. Therefore, we could repeatedly reproduce the near-room temperature upsurge of electrical resistance at a relatively early stage of the chemical reaction. However, the mechanism is suggested to be a metal-to-semiconductor/insulator transition associated with the structural modulation in the non-stoichiometric Lu-H-N, rather than superconductivity.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Detecting treeline dynamics in response to climate warming using forest stand maps and Landsat data in a temperate forest

引用

Forest Ecosystems 2018年第3期5卷 311-324页

作者： Maliheh Arekhi Ahmet Yesil Ulas Yunus Ozkan Fusun Balik Sanli institutes of graduate studies in science and enclineering Forest Ena neer haIstanbul University34452 IstanbulTurkey Faculty of Forestry Department or Forest ManagementIstanbul University34473 IstanbulTurkey Faculty of Civil Engineering Department of Geomatic EngineeringYlldlz Technical University34220 IstanbulTurkey

Background: Treeline dynamics have inevitable impacts on the forest treeline structure and composition. The present research sought to estimate treeline movement and structural shifts in response to recent warming in Cehennemdere, Turkey. After implementing an atmospheric correction, the geo-shifting of images was performed to match images together for a per pixel trend analysis. We developed a new approach based on the NDVI, LST(land surface temperature) data, air temperature data, and forest stand maps for a 43-year period. The forest treeline border was mapped on the forest stand maps for 1970, 1992, 2002, and 2013 to identify shifts in the treeline altitudes, and then profile statistics were calculated for each period. Twenty sample plots(10 × 10 pixels) were selected to estimatethe NDVI and LST shifts across the forest timberline using per-pixel trend analysis and non-parametric Spearman’s correlation analysis. In addition, the spatial and temporal shifts in treeline tree species were computed within the selected plots for four time periods on the forest stand maps to determine the pioneer tree ***: A statistically significant increasing trend in all climate variables was observed, with the highest slopein the monthly average mean July temperature(tau = 0.62, ρ < 0.00). The resultant forest stand maps showed a geographical expansion of the treeline in both the highest altitudes(22 m–45 m) and the lowest altitudes(20 m–105 m) from 1970 to 2013. The per pixel trend analysis indicated an increasing trend in the NDVI and LST values within the selected plots. Moreover, increases in the LST were highly correlated with increases in the NDVIbetween 1984 and 2017(r = 0.75, ρ < 0.05). Cedrus libani and Juniperus communis app. were two pioneer tree species that expanded and grew consistently on open lands, primarily on rocks and soil-covered areas, from 1970 to ***: The present study il ustrated that forest treeline dynamics and treeline structural

关键词： NDVI Geoshift LST Timberline Mann-Kendall Landsat Climate warming

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Study of first orbit losses of 1 MeV tritons using the Lorentz orbit code in the LHD

引用

Plasma science and Technology 2019年第2期21卷 21-25页

作者： Kunihiro OGAWA Mitsutaka ISOBE Takeo NISHITANI Sadayoshi MURAKAMI Ryosuke SEKI Hideo NUGA Neng PU Masaki OSAKABE LHD Experiment Group National Institute for Fusion science National Institutes of Natural Sciences SOKENDAI (The graduate University for Advanced studies) Kyoto University Kyoto-city

Shot-integrated measurement of the triton burnup ratio has been performed in the Large Helical Device. It was reported that the triton burnup ratio, defined as total DT neutron yield divided by total DD neutron yield, increases significantly in inward shifted configurations. To understand the magnetic configuration dependence of the triton burnup ratio, the first orbit loss fraction of 1 MeV tritons is evaluated by means of the Lorentz orbit code for various magnetic configurations. The first orbit loss of 1 MeV tritons is seen at t of less than 10-5 s and loss points of the triton are concentrated on the side of the helical coil case where the magnetic field is relatively weak. The significant decrease of the first orbit loss fraction by 15% is obtained with the inward shift of the magnetic axis position from 3.90 to 3.55 m. It is found that the decrease of first orbit loss is due to the reduction of the first orbit loss of transition and helically trapped tritons.

关键词： the Large Helical Device tritons energetic ion first orbit loss Lorentz orbit code

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Fenofibrate-promoted hepatomegaly and liver regeneration are PPARα-dependent and partially related to the YAP pathway

引用

Acta Pharmaceutica Sinica B 2024年第7期14卷 2992-3008页

作者： Shicheng Fan Yue Gao Pengfei Zhao Guomin Xie Yanying Zhou Xiao Yang Xuan Li Shuaishuai Zhang Frank JGonzalez Aijuan Qu Min Huangb Huichang Bi NMPA Key Laboratory for Research and Evaluation of Drug Metabolism&Guangdong Provincial Key Laboratory of New Drug Screening&Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening School of Pharmaceutical SciencesSouthern Medical UniversityGuangzhou 510515China Guangdong Provincial Key Laboratory of New Drug Design and Evaluation School of Pharmaceutical SciencesSun Yat-sen UniversityGuangzhou 510006China Department of Physiology and Pathophysiology School of Basic Medical SciencesCapital Medical UniversityBeijing 100069China Laboratory of Metabolism Center for Cancer ResearchNational Cancer InstituteNational Institutes of HealthBethesdaMD 20892USA The State Key Laboratory of Chemical Oncogenomics School of Chemical Biology and BiotechnologyShenzhen Graduate School of Peking UniversityShenzhen 518055China

Fenofibrate,a peroxisome proliferator-activated receptor α(PPARα)agonist,is widely prescribed for hyperlipidemia *** studies also showed that it has therapeutic potential in various liver ***,its effects on hepatomegaly and liver regeneration and the involved mechanisms remain ***,the study showed that fenofibrate significantly promoted liver enlargement and regeneration post-partial hepatectomy in mice,which was dependent on hepatocyteexpressed PPARα.Yes-associated protein(YAP)is pivotal in manipulating liver growth and *** further identified that fenofibrate activated YAP signaling by suppressing its K48-linked ubiquitination,promoting its K63-linked ubiquitination,and enhancing the interaction and transcriptional activity of the YAP-TEAD *** inhibition of YAP-TEAD interaction using verteporfin or suppression of YAP using AAV Yap shRNA in mice significantly attenuated fenofibrate-induced *** factors,such as MYC,KRT23,RAS,and RHOA,might also participate in fenofibrate-promoted hepatomegaly and liver *** studies demonstrate that fenofibratepromoted liver enlargement and regeneration are PPARα-dependent and partially through activating the YAP signaling,with clinical implications of fenofibrate as a novel therapeutic agent for promoting liver regeneration.

关键词： Fenofibrate PPARa Hepatomegaly Partial hepatectomy Liver regeneration YAP TEAD Ubiquitination

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effects of gamma-ray irradiation on electronic and non-electronic equipment of Large Helical Device

引用

Plasma science and Technology 2017年第2期19卷 95-100页

作者： K OGAWA T NISHITANI M ISOBE M SATO M YOKOTA H HAYASHI T KOBUCHI T NISHIMURA National Institute for Fusion science National Institutes of Natural Sciences322-6 0roshi-choToki 509-5292Japan SOKENDAI(The graduate University for Advanced studies) School of Physical Sciences322-6 Oroshi-choTold 509-5292Japan

In a deuterium operation on the Large Helical Device, the measurement and control equipment placed in the toms hall must survive under an environment of radiation, To study the effects of gamma-ray irradiation on the equipment, an irradiation experiment is performed at the Cobalt-60 irradiation facility of Nagoya University. Transient and permanent effects on a personal computer, media converters, programmable logic controllers, isolation amplifiers, a web camera, optical flow meters, and water sealing gaskets are experimentally surveyed. Transient noise appears on the web camera. Offset of the signal increases with an increase of the integrated dose on the programmable logic controller. The DeviceNet module on the programmable logic controller is broken at the integrated dose of 72 Gy, which is the expected range of the integrated dose of the toms hall. The other equipment can survive under the gamma-ray field in the toms hall.

关键词： large helical device gamma-ray irradiation radiation effect

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Metal‐organic frameworks‐derived novel nanostructured electrocatalysts for oxygen evolution reaction

引用

Carbon Energy 2021年第1期3卷 66-100页

作者： Xinyu Qin Dongwon Kim Yuanzhe Piao Department of Transdisciplinary studies Graduate School of Convergence Science and TechnologySeoul National UniversitySuwon‐siGyeonggi‐doRepublic of Korea Advanced institutes of Convergence Technology Seoul National UniversitySuwon‐siGyeonggi‐doRepublic of Korea

Engineering cost‐effective catalysts with exceptional performance for theelectrochemical oxygen evolution reaction (OER) remains crucial for theaccelerated development of renewable energy techniques, and especially so,given the pivotal role of OER in water electrolysis. On the basis of the metalnodes (clusters) and organic linkers, metal‐organic frameworks (MOFs) andtheir derivatives are rapidly gaining ground in the fabrication of electrocatalysts,with promising catalytic activity and sound durability in OER, thanksto their controllable pore structures, abundant unsaturated active sites of metalion, extensive specific surface area, as well as easily functionalized/modifiedsurfaces. This review presents an in‐depth understanding of the establishedprogress of MOFs‐derived materials for OER electrocatalysis. The materialdesigning strategies of the pristine, monometallic, and multimetallic MOFsbasedcatalysts are summarized to indicate the infinite possibilities of themorphology and the composition of MOF‐derived materials. While emphasisis laid on the essential features of MOF‐derived materials for the electrocatalysisof the corresponding reactions, insights about the applications in OERare discussed. Finally, this paper is concluded by presenting challengesand perspectives for MOF‐derived materials’ future applications in OERelectrocatalysis.

关键词： electrocatalyst high‐performance metal‐organic frameworks oxygen evolution reaction

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

New tomographic reconstruction technique based on Laplacian eigenfunction

引用

Plasma science and Technology 2020年第10期22卷 5-9页

作者： Yasuhiro SUZUKI Shishir PUROHIT Satoshi OHDACHI Satoshi YAMAMOTO Kazunobu NAGASAKI National Institute for Fusion science Toki 509-5292Japan The graduate University for Advanced studies SOKENDAIToki 509-5292Japan Institute for Plasma Research Gandhinagar 382428India graduate School of Frontier science The University of TokyoKashiwa 277-8561.Japan Naka Fusion Institute National Institutes for Quantum and Radiological Science and TechnologyNaka 311-0193Japan Institute of Advanced Energy Kyoto UniversityUji 611-0011Japan

This letter proposes a new tomographic reconstruction procedure based on the Laplacian eigenfunction(LEF) patterns, which are independent of the plasma cross-section and do not require the flux surface information. The process is benchmarked for the experimental data of Heliotron J plasma and the results are compared with the least-squares approximation by a Phillips–Tikhonov(PT)-type regularization, which is widely used as the standard technique for tomographic reconstruction. The reconstruction based on the LEF is found to be capable of determining the magnetic axis at different time locations efficiently in comparison with the PT-type regularization.

关键词： tomography Laplacian eigenfunction Heliotron J soft x-ray

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Line identification of boron and nitrogen emissions in extreme-and vacuumultraviolet wavelength ranges in the impurity powder dropping experiments of the Large Helical Device and its application to spectroscopic diagnostics

引用

Plasma science and Technology 2021年第8期23卷 6-17页

作者： Tetsutarou OISHI Naoko ASHIKAWA Federico NESPOLI Suguru MASUZAKI Mamoru SHOJI Eric P GILSON Robert LUNSFORD Shigeru MORITA Motoshi GOTO Yasuko KAWAMOTO Chihiro SUZUKI Zhen SUN Alex NAGY David A GATES Tomohiro MORISAKI Department of Fusion science The Graduate University for Advanced StudiesSOKENDAI322-6 Oroshi-choToki 509-5292GifuJapan Princeton Plasma Physics Laboratory 100 Stellarator RoadPrincetonNJ 08540United States of America National Institute for Fusion science National Institutes of Natural Sciences322-6 Oroshi-choToki 509-5292GifuJapan

An impurity powder dropper was installed in the 21 st campaign of the Large Helical Device experiment(Oct.2019–Feb.2020)under a collaboration between the National Institute for Fusion science and the Princeton Plasma Physics Laboratory for the purposes of real-time wall conditioning and edge plasma *** order to assess the effective injection of the impurity powders,spectroscopic diagnostics were applied to observe line emission from the injected ***,extreme-ultraviolet(EUV)and vacuum-ultraviolet(VUV)emission spectra were analyzed to summarize observable impurity lines with B and BN powder *** lines released from B and N ions were identified in the EUV wavelength range of 5–300Ameasured using two grazing incidence flat-field EUV spectrometers and in the VUV wavelength range of 300–2400Ameasured using three normal incidence 20 cm VUV ***–BV and NIII–NVII emission lines were identified in the discharges with the B and BN powder injection,*** B and N emission lines which have large intensities and are isolated from other lines were successfully identified as follows:BI(1825.89,1826.40)A(blended),BII 1362.46A,BIII(677.00,677.14,677.16)A(blended),BIV 60.31A,BV 48.59A,NIII(989.79,991.51,991.58)A(blended),NIV765.15A,NV(209.27,209.31)A(blended),NVI 1896.80A,and NVII *** of the line identifications to the advanced spectroscopic diagnostics were demonstrated,such as the vertical profile measurements for the BV and NVII lines using a space-resolved EUV spectrometer and the ion temperature measurement for the BII line using a normal incidence 3 m VUV spectrometer.

关键词： plasma spectroscopy extreme ultraviolet vacuum ultraviolet magnetically confined fusion impurity seeding wall conditioning

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：